Opposing and synergistic effects of cyclic mechanical stretch and α- or β-adrenergic stimulation on the cardiac gap junction protein Cx43

Pharmacological Research

Volumn 62, Issue 6, 2010, Pages 506-513

  Salameh, Aida ^a   Karl, Sebastian ^a   Djilali, Hjalmar ^a   Dhein, Stefan ^a   Janousek, Jan ^b   Daehnert, Ingo ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

AKT; Alpha adrenoceptor; Beta adrenoceptor; Cardiomyocytes; Connexin43; Cyclic mechanical stretch; ERK

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CONNEXIN 43; GAP JUNCTION PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; ISOPRENALINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENYLEPHRINE; PROTEIN KINASE B;

ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ARTICLE; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HEART CELL CULTURE; HEART MUSCLE CELL; INCUBATION TIME; LONG TERM EXPOSURE; MECHANICAL STIMULATION; MECHANICAL STRESS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ADRENERGIC AGONISTS; ANIMALS; CELLS, CULTURED; CONNEXIN 43; ISOPROTERENOL; MYOCYTES, CARDIAC; PHENYLEPHRINE; RATS; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, ADRENERGIC, BETA; RNA, MESSENGER; UP-REGULATION;

EID: 78049529230     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2010.08.002     Document Type: Article

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