메뉴 건너뛰기




Volumn , Issue , 2007, Pages 105-114

Nitric Oxide and Systemic and Renal Hemodynamic Disturbances in Cirrhosis

Author keywords

Catalysis; Cirrhosis; Neurotoxicity; Nitric oxide; Soluble guanylate cyclase (sGC)

Indexed keywords


EID: 78049482211     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470987476.ch8     Document Type: Chapter
Times cited : (5)

References (99)
  • 1
    • 0022993474 scopus 로고
    • Activation of soluble guanylate cyclase by NO-hemoproteins involves NO-heme exchange. Comparison of heme-containing and heme-defi cient enzyme forms
    • Ignarro LJ, Adams JB, Horwitz PM, Wood KS. Activation of soluble guanylate cyclase by NO-hemoproteins involves NO-heme exchange. Comparison of heme-containing and heme-defi cient enzyme forms. J Biol Chem 1986; 261:4997-5002.
    • (1986) J Biol Chem , vol.261 , pp. 4997-5002
    • Ignarro, L.J.1    Adams, J.B.2    Horwitz, P.M.3    Wood, K.S.4
  • 2
    • 0025802065 scopus 로고
    • Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase
    • Bredt DS, Hwang PM, Glatt CE, Lowenstein C, Reed RR, Snyder SH. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature 1991; 351:714-18.
    • (1991) Nature , vol.351 , pp. 714-718
    • Bredt, D.S.1    Hwang, P.M.2    Glatt, C.E.3    Lowenstein, C.4    Reed, R.R.5    Snyder, S.H.6
  • 3
    • 0026729267 scopus 로고
    • Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme
    • Lowenstein CJ, Glatt CS, Bredt DS, Snyder SH. Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proc Natl Acad Sci USA 1992; 89:6711-15.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6711-6715
    • Lowenstein, C.J.1    Glatt, C.S.2    Bredt, D.S.3    Snyder, S.H.4
  • 4
    • 0026744830 scopus 로고
    • Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line
    • Lyons CR, Orloff GJ, Cunningham JM. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J Biol Chem 1992; 267:6370-4.
    • (1992) J Biol Chem , vol.267 , pp. 6370-6374
    • Lyons, C.R.1    Orloff, G.J.2    Cunningham, J.M.3
  • 5
    • 0026623110 scopus 로고
    • Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform
    • Lamas S, Marsden PA, Li GK, Tempst P, Michel T. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc Natl Acad Sci USA 1992; 89:6348-52.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6348-6352
    • Lamas, S.1    Marsden, P.A.2    Li, G.K.3    Tempst, P.4    Michel, T.5
  • 6
    • 0026764107 scopus 로고
    • Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase
    • Sessa WC, Harrison JK, Barber CM et al. Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase. J Biol Chem 1992; 267:15274-6.
    • (1992) J Biol Chem , vol.267 , pp. 15274-15276
    • Sessa, W.C.1    Harrison, J.K.2    Barber, C.M.3
  • 7
    • 0027975453 scopus 로고
    • Nitric oxide: a physiologic messenger molecule
    • Bredt DS, Snyder SH. Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem 1994; 63:175-95.
    • (1994) Annu Rev Biochem , vol.63 , pp. 175-195
    • Bredt, D.S.1    Snyder, S.H.2
  • 9
    • 0025883342 scopus 로고
    • Nitric oxide: physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43:109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 10
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992; 6:3051-64.
    • (1992) FASEB J , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 11
    • 0037216768 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase
    • Fleming I, Busse R. Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol 2003; 284:R1-12.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284
    • Fleming, I.1    Busse, R.2
  • 12
    • 0036883907 scopus 로고    scopus 로고
    • Blocking NO synthesis: how, where and why?
    • Vallance P, Leiper J. Blocking NO synthesis: how, where and why? Nat Rev Drug Discov 2002; 1:939-50.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 939-950
    • Vallance, P.1    Leiper, J.2
  • 13
    • 0026518464 scopus 로고
    • Pathogenesis of arterial hypotension in cirrhotic rats with ascites: role of endogenous nitric oxide
    • Clària J, Jiménez W, Ros J et al. Pathogenesis of arterial hypotension in cirrhotic rats with ascites: role of endogenous nitric oxide. Hepatology 1992; 15:343-9.
    • (1992) Hepatology , vol.15 , pp. 343-349
    • Clària, J.1    Jiménez, W.2    Ros, J.3
  • 14
    • 0028829527 scopus 로고
    • Normalization of nitric oxide production corrects arterial vasodilation and hyperdynamic circulation in cirrhotic rats
    • Niederberger M, Martin PY, Ginès P et al. Normalization of nitric oxide production corrects arterial vasodilation and hyperdynamic circulation in cirrhotic rats. Gastroenterology 1995; 109:1624-30.
    • (1995) Gastroenterology , vol.109 , pp. 1624-1630
    • Niederberger, M.1    Martin, P.Y.2    Ginès, P.3
  • 15
    • 0028905429 scopus 로고
    • Nitric oxide production in arterial vessels of cirrhotic rats
    • Ros J, Jiménez W, Lamas S et al. Nitric oxide production in arterial vessels of cirrhotic rats. Hepatology 1995; 21:554-60.
    • (1995) Hepatology , vol.21 , pp. 554-560
    • Ros, J.1    Jiménez, W.2    Lamas, S.3
  • 16
    • 0027946525 scopus 로고
    • Increased nitric oxidedependent vasorelaxation in aortic rings of cirrhotic rats with ascites
    • Clària J, Jiménez W, Ros J et al. Increased nitric oxidedependent vasorelaxation in aortic rings of cirrhotic rats with ascites. Hepatology 1994; 20:1615-21.
    • (1994) Hepatology , vol.20 , pp. 1615-1621
    • Clària, J.1    Jiménez, W.2    Ros, J.3
  • 17
    • 0029786248 scopus 로고    scopus 로고
    • Comparison of vascular nitric oxide production and systemic hemodynamics in cirrhosis versus prehepatic portal hypertension in rats
    • Niederberger M, Ginès P, Martin PY et al. Comparison of vascular nitric oxide production and systemic hemodynamics in cirrhosis versus prehepatic portal hypertension in rats. Hepatology 1996; 24:947-51.
    • (1996) Hepatology , vol.24 , pp. 947-951
    • Niederberger, M.1    Ginès, P.2    Martin, P.Y.3
  • 18
    • 0027178984 scopus 로고
    • Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide
    • Castro A, Jiménez W, Clària J et al. Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide. Hepatology 1993; 18:367-72.
    • (1993) Hepatology , vol.18 , pp. 367-372
    • Castro, A.1    Jiménez, W.2    Clària, J.3
  • 19
    • 0027236198 scopus 로고
    • Role of nitric oxide in the in vitro splanchnic vascular hyporeactivity in ascitic cirrhotic rats
    • Sieber CC, López-Talavera JC, Groszmann RJ. Role of nitric oxide in the in vitro splanchnic vascular hyporeactivity in ascitic cirrhotic rats. Gastroenterology 1993; 104:1750-4.
    • (1993) Gastroenterology , vol.104 , pp. 1750-1754
    • Sieber, C.C.1    López-Talavera, J.C.2    Groszmann, R.J.3
  • 20
    • 0026708176 scopus 로고
    • Vitro hyporeactivity to methoxamine in portal hypertensive rats: reversal by nitric oxide blockade
    • Sieber CC, Groszmann RJ. In vitro hyporeactivity to methoxamine in portal hypertensive rats: reversal by nitric oxide blockade. Am J Physiol 1992; 262:G996-1001.
    • (1992) Am J Physiol , vol.262
    • Sieber, C.C.1    Groszmann, R.J.2
  • 21
    • 0026737603 scopus 로고
    • The role of nitric oxide in the vascular hyporesponsiveness to methoxamine in portal hypertensive rats
    • Lee FY, Albillos A, Colombato LA, Groszmann RJ. The role of nitric oxide in the vascular hyporesponsiveness to methoxamine in portal hypertensive rats. Hepatology 1992; 16:1043-8.
    • (1992) Hepatology , vol.16 , pp. 1043-1048
    • Lee, F.Y.1    Albillos, A.2    Colombato, L.A.3    Groszmann, R.J.4
  • 23
    • 0029965368 scopus 로고    scopus 로고
    • Upregulation of endothelial constitutive NOS: a major role in the increased NO production in cirrhotic rats
    • Martin PY, Xu DL, Niederberger M et al. Upregulation of endothelial constitutive NOS: a major role in the increased NO production in cirrhotic rats. Am J Physiol 1996; 270: F494-F499.
    • (1996) Am J Physiol , vol.270
    • Martin, P.Y.1    Xu, D.L.2    Niederberger, M.3
  • 24
    • 0029967901 scopus 로고    scopus 로고
    • Increased nitric oxide synthase expression in arterial vessels of cirrhotic rats with ascites
    • Morales-Ruiz M, Jiménez W, Pérez-Sala D et al. Increased nitric oxide synthase expression in arterial vessels of cirrhotic rats with ascites. Hepatology 1996; 24:1481-6.
    • (1996) Hepatology , vol.24 , pp. 1481-1486
    • Morales-Ruiz, M.1    Jiménez, W.2    Pérez-Sala, D.3
  • 25
    • 0034538057 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase and systemic vasodilation in rats with cirrhosis
    • Xu L, Carter EP, Ohara M et al. Neuronal nitric oxide synthase and systemic vasodilation in rats with cirrhosis. Am J Physiol Renal Physiol 2000; 279:F1110-F1115.
    • (2000) Am J Physiol Renal Physiol , vol.279
    • Xu, L.1    Carter, E.P.2    Ohara, M.3
  • 27
    • 0030248313 scopus 로고    scopus 로고
    • Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats
    • Cahill PA, Redmond EM, Hodges R, Zhang S, Sitzmann JV. Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats. J Hepatol 1996; 25:370-8.
    • (1996) J Hepatol , vol.25 , pp. 370-378
    • Cahill, P.A.1    Redmond, E.M.2    Hodges, R.3    Zhang, S.4    Sitzmann, J.V.5
  • 28
    • 0032821921 scopus 로고    scopus 로고
    • Abnormal regulation of aortic NOS2 and NOS3 activity and expression from portal vein-stenosed rats after lipopolysaccharide administration
    • Heller J, Sogni P, Tazi KA et al. Abnormal regulation of aortic NOS2 and NOS3 activity and expression from portal vein-stenosed rats after lipopolysaccharide administration. Hepatology 1999; 30:698-704.
    • (1999) Hepatology , vol.30 , pp. 698-704
    • Heller, J.1    Sogni, P.2    Tazi, K.A.3
  • 29
    • 0033515873 scopus 로고    scopus 로고
    • Increased nitric oxide synthase expression in aorta of cirrhotic rats
    • Liu H, Song D, Lee SS. Increased nitric oxide synthase expression in aorta of cirrhotic rats. Life Sci 1999; 64:1753-9.
    • (1999) Life Sci , vol.64 , pp. 1753-1759
    • Liu, H.1    Song, D.2    Lee, S.S.3
  • 30
    • 0036080028 scopus 로고    scopus 로고
    • Role of shear stress in aortic eNOS up-regulation in rats with biliary cirrhosis
    • Tazi KA, Barriere E, Moreau R et al. Role of shear stress in aortic eNOS up-regulation in rats with biliary cirrhosis. Gastroenterology 2002; 122:1869-77.
    • (2002) Gastroenterology , vol.122 , pp. 1869-1877
    • Tazi, K.A.1    Barriere, E.2    Moreau, R.3
  • 31
    • 0036903724 scopus 로고    scopus 로고
    • Endothelial, but not the inducible, nitric oxide synthase is detectable in normal and portal hypertensive rats
    • Stumm MM, D'Orazio D, Sumanovski LT, Martin PY, Reichen J, Sieber CC. Endothelial, but not the inducible, nitric oxide synthase is detectable in normal and portal hypertensive rats. Liver 2002; 22:441-50.
    • (2002) Liver , vol.22 , pp. 441-450
    • Stumm, M.M.1    D'Orazio, D.2    Sumanovski, L.T.3    Martin, P.Y.4    Reichen, J.5    Sieber, C.C.6
  • 32
  • 33
    • 0037621928 scopus 로고    scopus 로고
    • The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice
    • Theodorakis NG, Wang YN, Skill NJ et al. The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice. Gastroenterology 2003; 124:1500-8.
    • (2003) Gastroenterology , vol.124 , pp. 1500-1508
    • Theodorakis, N.G.1    Wang, Y.N.2    Skill, N.J.3
  • 34
    • 0028956293 scopus 로고
    • Enhanced endotheliumdependent vasodilation in patients with cirrhosis
    • Albillos A, Rossi I, Cacho G et al. Enhanced endotheliumdependent vasodilation in patients with cirrhosis. Am J Physiol 1995; 268:G459-G464.
    • (1995) Am J Physiol , vol.268
    • Albillos, A.1    Rossi, I.2    Cacho, G.3
  • 35
    • 0027438813 scopus 로고
    • Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia
    • Guarner C, Soriano G, Tomás A et al. Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia. Hepatology 1993; 18:1139-43.
    • (1993) Hepatology , vol.18 , pp. 1139-1143
    • Guarner, C.1    Soriano, G.2    Tomás, A.3
  • 36
  • 37
    • 0031036533 scopus 로고    scopus 로고
    • Hyperdynamic circulation in patients with cirrhosis: direct measurement of nitric oxide levels in hepatic and portal veins
    • Battista S, Bar F, Mengozzi G, Zanon E, Grosso M, Molino G. Hyperdynamic circulation in patients with cirrhosis: direct measurement of nitric oxide levels in hepatic and portal veins. J Hepatol 1997; 26:75-80.
    • (1997) J Hepatol , vol.26 , pp. 75-80
    • Battista, S.1    Bar, F.2    Mengozzi, G.3    Zanon, E.4    Grosso, M.5    Molino, G.6
  • 38
    • 0034793892 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in the splanchnic vasculature of patients with cirrhosis: relationship with hemodynamic disturbances
    • Albornoz L, Motta A, Alvarez D et al. Nitric oxide synthase activity in the splanchnic vasculature of patients with cirrhosis: relationship with hemodynamic disturbances. J Hepatol 2001; 35:452-6.
    • (2001) J Hepatol , vol.35 , pp. 452-456
    • Albornoz, L.1    Motta, A.2    Alvarez, D.3
  • 39
    • 0029152084 scopus 로고
    • Increased nitric oxide in the exhaled air of patients with decompensated liver cirrhosis
    • Matsumoto A, Ogura K, Hirata Y et al. Increased nitric oxide in the exhaled air of patients with decompensated liver cirrhosis. Ann Intern Med 1995; 123:110-13.
    • (1995) Ann Intern Med , vol.123 , pp. 110-113
    • Matsumoto, A.1    Ogura, K.2    Hirata, Y.3
  • 40
    • 0028990525 scopus 로고
    • Endogenous pulmonary nitric oxide production measured from exhaled air is increased in patients with severe cirrhosis
    • Sogni P, Garnier P, Gadano A et al. Endogenous pulmonary nitric oxide production measured from exhaled air is increased in patients with severe cirrhosis. J Hepatol 1995; 23:471-3.
    • (1995) J Hepatol , vol.23 , pp. 471-473
    • Sogni, P.1    Garnier, P.2    Gadano, A.3
  • 42
    • 0028841506 scopus 로고
    • Increased production of nitric oxide by neutrophils and monocytes from cirrhotic patients with ascites and hyperdynamic circulation
    • Laffi G, Foschi M, Masini E et al. Increased production of nitric oxide by neutrophils and monocytes from cirrhotic patients with ascites and hyperdynamic circulation. Hepatology 1995; 22:1666-73.
    • (1995) Hepatology , vol.22 , pp. 1666-1673
    • Laffi, G.1    Foschi, M.2    Masini, E.3
  • 43
    • 0032842338 scopus 로고    scopus 로고
    • Nitric oxide production and inducible nitric oxide synthase expression in peritoneal macrophages of cirrhotic patients
    • Jiménez W, Ros J, Morales-Ruiz M et al. Nitric oxide production and inducible nitric oxide synthase expression in peritoneal macrophages of cirrhotic patients. Hepatology 1999; 30:670-6.
    • (1999) Hepatology , vol.30 , pp. 670-676
    • Jiménez, W.1    Ros, J.2    Morales-Ruiz, M.3
  • 44
    • 0030898224 scopus 로고    scopus 로고
    • Nitric oxide production by peritoneal macrophages of cirrhotic rats: a host response against bacterial peritonitis
    • Morales-Ruiz M, Jimenez W, Ros J et al. Nitric oxide production by peritoneal macrophages of cirrhotic rats: a host response against bacterial peritonitis. Gastroenterology 1997; 112:2056-64.
    • (1997) Gastroenterology , vol.112 , pp. 2056-2064
    • Morales-Ruiz, M.1    Jimenez, W.2    Ros, J.3
  • 45
    • 0028868632 scopus 로고
    • Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis
    • Campillo B, Chabrier PE, Pelle G et al. Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis. Hepatology 1995; 22:1423-9.
    • (1995) Hepatology , vol.22 , pp. 1423-1429
    • Campillo, B.1    Chabrier, P.E.2    Pelle, G.3
  • 46
    • 0034957736 scopus 로고    scopus 로고
    • Hemodynamic, renal, and endocrine effects of acute inhibition of nitric oxide synthase in compensated cirrhosis
    • La Villa G, Barletta G, Pantaleo P et al. Hemodynamic, renal, and endocrine effects of acute inhibition of nitric oxide synthase in compensated cirrhosis. Hepatology 2001; 34:19-27.
    • (2001) Hepatology , vol.34 , pp. 19-27
    • La Villa, G.1    Barletta, G.2    Pantaleo, P.3
  • 47
    • 0037259561 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition does not improve renal function in cirrhotic patients with ascites
    • Thiesson HC, Skott O, Jespersen B, Schaffalitzky de Muckadell OB. Nitric oxide synthase inhibition does not improve renal function in cirrhotic patients with ascites. Am J Gastroenterol 2003; 98:180-6.
    • (2003) Am J Gastroenterol , vol.98 , pp. 180-186
    • Thiesson, H.C.1    Skott, O.2    Jespersen, B.3    Schaffalitzky De Muckadell, O.B.4
  • 48
    • 0037568328 scopus 로고    scopus 로고
    • Nitric oxide synthase 3-dependent vascular remodeling and circulatory dysfunction in cirrhosis
    • Fernández-Varo G, Ros J, Morales-Ruiz M et al. Nitric oxide synthase 3-dependent vascular remodeling and circulatory dysfunction in cirrhosis. Am J Pathol 2003; 162:1985-93.
    • (2003) Am J Pathol , vol.162 , pp. 1985-1993
    • Fernández-Varo, G.1    Ros, J.2    Morales-Ruiz, M.3
  • 49
    • 0030794209 scopus 로고    scopus 로고
    • NO-mediated vasodilation in the rat liver. Role of hepatocytes and liver endothelial cells
    • Zhang B, Borderie D, Sogni P, Soubrane O, Houssin D, Calmus Y. NO-mediated vasodilation in the rat liver. Role of hepatocytes and liver endothelial cells. J Hepatol 1997; 26:1348-55.
    • (1997) J Hepatol , vol.26 , pp. 1348-1355
    • Zhang, B.1    Borderie, D.2    Sogni, P.3    Soubrane, O.4    Houssin, D.5    Calmus, Y.6
  • 50
    • 0030729890 scopus 로고    scopus 로고
    • Role of nitric oxide in the regulation of the hepatic microcirculation in vivo
    • Bauer C, Walcher F, Kalweit U, Larsen R, Marzi I. Role of nitric oxide in the regulation of the hepatic microcirculation in vivo. J Hepatol 1997; 27:1089-95.
    • (1997) J Hepatol , vol.27 , pp. 1089-1095
    • Bauer, C.1    Walcher, F.2    Kalweit, U.3    Larsen, R.4    Marzi, I.5
  • 52
    • 0031442394 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids
    • Shah V, Haddad FG, Garcia-Cardena G et al. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids. J Clin Invest 1997; 100:2923-30.
    • (1997) J Clin Invest , vol.100 , pp. 2923-2930
    • Shah, V.1    Haddad, F.G.2    Garcia-Cardena, G.3
  • 53
    • 0031682956 scopus 로고    scopus 로고
    • Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats
    • Gupta TK, Toruner M, Chung MK, Groszmann RJ. Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats. Hepatology 1998; 28:926-31.
    • (1998) Hepatology , vol.28 , pp. 926-931
    • Gupta, T.K.1    Toruner, M.2    Chung, M.K.3    Groszmann, R.J.4
  • 54
    • 0031941122 scopus 로고    scopus 로고
    • Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension
    • Rockey DC, Chung JJ. Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension. Gastroenterology 1998; 114:344-51.
    • (1998) Gastroenterology , vol.114 , pp. 344-351
    • Rockey, D.C.1    Chung, J.J.2
  • 56
    • 0032738990 scopus 로고    scopus 로고
    • Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat
    • Shah V, Toruner M, Haddad F et al. Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat. Gastroenterology 1999; 117:1222-8.
    • (1999) Gastroenterology , vol.117 , pp. 1222-1228
    • Shah, V.1    Toruner, M.2    Haddad, F.3
  • 58
    • 0036274032 scopus 로고    scopus 로고
    • Enhanced expression of endothelial nitric oxide synthase and caveolin-1 in human cirrhosis
    • Yokomori H, Oda M, Ogi M, Sakai K, Ishii H. Enhanced expression of endothelial nitric oxide synthase and caveolin-1 in human cirrhosis. Liver 2002; 22:150-8.
    • (2002) Liver , vol.22 , pp. 150-158
    • Yokomori, H.1    Oda, M.2    Ogi, M.3    Sakai, K.4    Ishii, H.5
  • 59
    • 0042666939 scopus 로고    scopus 로고
    • Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats
    • Morales-Ruiz M, Cejudo-Martin P, Fernández-Varo G et al. Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats. Gastroenterology 2003; 125:522-31.
    • (2003) Gastroenterology , vol.125 , pp. 522-531
    • Morales-Ruiz, M.1    Cejudo-Martin, P.2    Fernández-Varo, G.3
  • 60
    • 0035192750 scopus 로고    scopus 로고
    • Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough?
    • Fulton D, Gratton JP, Sessa WC. Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther 2001; 299:818-24.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 818-824
    • Fulton, D.1    Gratton, J.P.2    Sessa, W.C.3
  • 61
    • 12644262388 scopus 로고    scopus 로고
    • Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis
    • Rolla G, Brussino L, Colagrande P et al. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrhosis. Hepatology 1997; 26:842-7.
    • (1997) Hepatology , vol.26 , pp. 842-847
    • Rolla, G.1    Brussino, L.2    Colagrande, P.3
  • 62
    • 0028799812 scopus 로고
    • Elevated exhaled nitric oxide in patients with hepatopulmonary syndrome
    • Cremona G, Higenbottam TW, Mayoral V et al. Elevated exhaled nitric oxide in patients with hepatopulmonary syndrome. Eur Respir J 1995; 8:1883-5.
    • (1995) Eur Respir J , vol.8 , pp. 1883-1885
    • Cremona, G.1    Higenbottam, T.W.2    Mayoral, V.3
  • 63
    • 0036469044 scopus 로고    scopus 로고
    • Increased nitric oxide output from alveolar origin during liver cirrhosis versus bronchial source during asthma
    • Delclaux C, Mahut B, Zerah-Lancner F et al. Increased nitric oxide output from alveolar origin during liver cirrhosis versus bronchial source during asthma. Am J Resp Crit Care Med 2002; 165:332-7.
    • (2002) Am J Resp Crit Care Med , vol.165 , pp. 332-337
    • Delclaux, C.1    Mahut, B.2    Zerah-Lancner, F.3
  • 64
    • 0028109096 scopus 로고
    • Mixed expired nitric oxide in primary pulmonary hypertension in relation to lung diffusion capacity
    • Cremona G, Higenbottam T, Borland C, Mist B. Mixed expired nitric oxide in primary pulmonary hypertension in relation to lung diffusion capacity. Q J Med 1994; 87:547-51.
    • (1994) Q J Med , vol.87 , pp. 547-551
    • Cremona, G.1    Higenbottam, T.2    Borland, C.3    Mist, B.4
  • 65
    • 15644370478 scopus 로고    scopus 로고
    • Exhaled nitric oxide and impaired oxygenation in cirrhotic patients before and after liver transplantation
    • Rolla G, Brussino L, Colagrande P et al. Exhaled nitric oxide and impaired oxygenation in cirrhotic patients before and after liver transplantation. Ann Intern Med 1998; 129: 375-8.
    • (1998) Ann Intern Med , vol.129 , pp. 375-378
    • Rolla, G.1    Brussino, L.2    Colagrande, P.3
  • 66
    • 0030877449 scopus 로고    scopus 로고
    • The role of endothelial nitric oxide synthase in the pathogenesis of a rat model of hepatopulmonary syndrome
    • Fallon MB, Abrams GA, Luo B, Hou Z, Dai J, Ku DD. The role of endothelial nitric oxide synthase in the pathogenesis of a rat model of hepatopulmonary syndrome. Gastroenterology 1997; 113:606-14.
    • (1997) Gastroenterology , vol.113 , pp. 606-614
    • Fallon, M.B.1    Abrams, G.A.2    Luo, B.3    Hou, Z.4    Dai, J.5    Ku, D.D.6
  • 67
    • 0033681862 scopus 로고    scopus 로고
    • Inhibition of K(Ca) channels restores blunted hypoxic pulmonary vasoconstriction in rats with cirrhosis
    • Carter EP, Sato K, Morio Y, McMurtry IF. Inhibition of K(Ca) channels restores blunted hypoxic pulmonary vasoconstriction in rats with cirrhosis. Am J Physiol Lung Cell Mol Physiol 2000; 279:L903-L910.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Carter, E.P.1    Sato, K.2    Morio, Y.3    McMurtry, I.F.4
  • 68
    • 0031194063 scopus 로고    scopus 로고
    • NO as an indicator of portal hemodynamics and the role of iNOS in increased NO production in CCl4-induced liver cirrhosis
    • Mizumoto M, Arii S, Furutani M et al. NO as an indicator of portal hemodynamics and the role of iNOS in increased NO production in CCl4-induced liver cirrhosis. J Surg Res 1997; 70:124-33.
    • (1997) J Surg Res , vol.70 , pp. 124-133
    • Mizumoto, M.1    Arii, S.2    Furutani, M.3
  • 69
    • 0035050742 scopus 로고    scopus 로고
    • Role of nitric oxide (NO) in pulmonary dysfunction associated with experimental cirrhosis
    • Nelson RS, Eichinger MR. Role of nitric oxide (NO) in pulmonary dysfunction associated with experimental cirrhosis. Respir Physiol 2001; 126:65-74.
    • (2001) Respir Physiol , vol.126 , pp. 65-74
    • Nelson, R.S.1    Eichinger, M.R.2
  • 70
    • 0035447978 scopus 로고    scopus 로고
    • Role of nitric oxide in hepatopulmonary syndrome in cirrhotic rats
    • Nunes H, Lebrec D, Mazmanian M et al. Role of nitric oxide in hepatopulmonary syndrome in cirrhotic rats. Am J Resp Crit Care Med 2001; 164:879-85.
    • (2001) Am J Resp Crit Care Med , vol.164 , pp. 879-885
    • Nunes, H.1    Lebrec, D.2    Mazmanian, M.3
  • 71
    • 0033755748 scopus 로고    scopus 로고
    • Is there a cirrhotic cardiomyopathy?
    • Blendis L, Wong F. Is there a cirrhotic cardiomyopathy? Am J Gastroenterol 2000; 95:3026-8.
    • (2000) Am J Gastroenterol , vol.95 , pp. 3026-3028
    • Blendis, L.1    Wong, F.2
  • 72
    • 0030880931 scopus 로고    scopus 로고
    • Altered cardiovascular responsiveness to active tilting in nonalcoholic cirrhosis
    • Laffi G, Barletta G, La Villa G et al. Altered cardiovascular responsiveness to active tilting in nonalcoholic cirrhosis. Gastroenterology 1997; 113:891-8.
    • (1997) Gastroenterology , vol.113 , pp. 891-898
    • Laffi, G.1    Barletta, G.2    La Villa, G.3
  • 73
    • 0029145769 scopus 로고
    • Decreased right heart blood volume determined by magnetic resonance imaging: evidence of central underfi lling in cirrhosis
    • Moller S, Sondergaard L, Mogelvang J, Henriksen O, Henriksen JH. Decreased right heart blood volume determined by magnetic resonance imaging: evidence of central underfi lling in cirrhosis. Hepatology 1995; 22: 472-8.
    • (1995) Hepatology , vol.22 , pp. 472-478
    • Moller, S.1    Sondergaard, L.2    Mogelvang, J.3    Henriksen, O.4    Henriksen, J.H.5
  • 74
    • 0021210773 scopus 로고
    • Cardiac performance in patients with asymptomatic alcoholic cirrhosis of the liver
    • Kelbaek H, Eriksen J, Brynjolf I et al. Cardiac performance in patients with asymptomatic alcoholic cirrhosis of the liver. Am J Cardiol 1984; 54:852-5.
    • (1984) Am J Cardiol , vol.54 , pp. 852-855
    • Kelbaek, H.1    Eriksen, J.2    Brynjolf, I.3
  • 75
    • 0029778989 scopus 로고    scopus 로고
    • Cirrhotic cardiomyopathy: getting to the heart of the matter
    • Ma Z, Lee SS. Cirrhotic cardiomyopathy: getting to the heart of the matter. Hepatology 1996; 24:451-9.
    • (1996) Hepatology , vol.24 , pp. 451-459
    • Ma, Z.1    Lee, S.S.2
  • 76
    • 12644271202 scopus 로고    scopus 로고
    • Evidence of functional and structural cardiac abnormalities in cirrhotic patients with and without ascites
    • Pozzi M, Carugo S, Boari G et al. Evidence of functional and structural cardiac abnormalities in cirrhotic patients with and without ascites. Hepatology 1997; 26:1131-7.
    • (1997) Hepatology , vol.26 , pp. 1131-1137
    • Pozzi, M.1    Carugo, S.2    Boari, G.3
  • 77
    • 0030158339 scopus 로고    scopus 로고
    • Cardiac modifi cations occurring in the ascitic rat with biliary cirrhosis are nitric oxide related
    • Van Obbergh L, Vallieres Y, Blaise G. Cardiac modifi cations occurring in the ascitic rat with biliary cirrhosis are nitric oxide related. J Hepatol 1996; 24:747-52.
    • (1996) J Hepatol , vol.24 , pp. 747-752
    • Van Obbergh, L.1    Vallieres, Y.2    Blaise, G.3
  • 78
    • 0034058877 scopus 로고    scopus 로고
    • Contribution of nitric oxide to the pathogenesis of cirrhotic cardiomyopathy in bile ductligated rats
    • Liu H, Ma Z, Lee SS. Contribution of nitric oxide to the pathogenesis of cirrhotic cardiomyopathy in bile ductligated rats. Gastroenterology 2000; 118:937-44.
    • (2000) Gastroenterology , vol.118 , pp. 937-944
    • Liu, H.1    Ma, Z.2    Lee, S.S.3
  • 79
    • 13444283154 scopus 로고    scopus 로고
    • Renal function in liver disease
    • In: Greenberg A, Coffman TM, eds., 3rd edn. San Diego, CA: Academic Press
    • Arroyo V, Jiménez W. Renal function in liver disease. In: Greenberg A, Coffman TM, eds. Primer on Kidney Diseases, 3rd edn. San Diego, CA: Academic Press, 2001; 188-94.
    • (2001) Primer on Kidney Diseases , pp. 188-194
    • Arroyo, V.1    Jiménez, W.2
  • 81
    • 0029080711 scopus 로고
    • Role of nitric oxide and prostacyclin in the control of renal perfusion in experimental cirrhosis
    • Ros J, Clària J, Jiménez W et al. Role of nitric oxide and prostacyclin in the control of renal perfusion in experimental cirrhosis. Hepatology 1995; 22:915-20.
    • (1995) Hepatology , vol.22 , pp. 915-920
    • Ros, J.1    Clària, J.2    Jiménez, W.3
  • 82
    • 0028566440 scopus 로고
    • Efectos de la inhibición de la síntesis de oxido nítrico en la hemodinámica y excreción renal de ratas con cirrosis biliar primaria
    • Ramírez A, Atucha NM, Pérez MC et al. Efectos de la inhibición de la síntesis de oxido nítrico en la hemodinámica y excreción renal de ratas con cirrosis biliar primaria. Nefrología 1994; 14:656-62.
    • (1994) Nefrología , vol.14 , pp. 656-662
    • Ramírez, A.1    Atucha, N.M.2    Pérez, M.C.3
  • 83
    • 0031975181 scopus 로고    scopus 로고
    • Nitric oxide synthase (NOS) inhibition for one week improves renal sodium and water excretion in cirrhotic rats with ascites
    • Martin PY, Ohara M, Ginès P et al. Nitric oxide synthase (NOS) inhibition for one week improves renal sodium and water excretion in cirrhotic rats with ascites. J Clin Invest 1998; 101:235-42.
    • (1998) J Clin Invest , vol.101 , pp. 235-242
    • Martin, P.Y.1    Ohara, M.2    Ginès, P.3
  • 84
    • 0030549949 scopus 로고    scopus 로고
    • Intrarenal alterations in experimental liver cirrhosis
    • Atucha NM, Garcia-Estan J. Intrarenal alterations in experimental liver cirrhosis. News Physiol Sci 1996; 11:48-52.
    • (1996) News Physiol Sci , vol.11 , pp. 48-52
    • Atucha, N.M.1    Garcia-Estan, J.2
  • 85
    • 0030198615 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in portal-hypertensive and cirrhotic rats
    • Kanwar S, Kubes P, Tepperman BL, Lee SS. Nitric oxide synthase activity in portal-hypertensive and cirrhotic rats. J Hepatol 1996; 25:85-9.
    • (1996) J Hepatol , vol.25 , pp. 85-89
    • Kanwar, S.1    Kubes, P.2    Tepperman, B.L.3    Lee, S.S.4
  • 86
    • 0030757973 scopus 로고    scopus 로고
    • Elevated glomerular and blood mononuclear lymphocyte nitric oxide production in rats with chronic bile duct ligation: role of inducible nitric oxide synthase activation
    • Criado M, Flores O, Ortiz MC et al. Elevated glomerular and blood mononuclear lymphocyte nitric oxide production in rats with chronic bile duct ligation: role of inducible nitric oxide synthase activation. Hepatology 1997; 26:268-76.
    • (1997) Hepatology , vol.26 , pp. 268-276
    • Criado, M.1    Flores, O.2    Ortiz, M.C.3
  • 88
    • 17344370671 scopus 로고    scopus 로고
    • Increased renal expression of nitric oxide synthase type III in cirrhotic rats with ascites
    • Bosch-Marcé M, Morales-Ruiz M, Jiménez W et al. Increased renal expression of nitric oxide synthase type III in cirrhotic rats with ascites. Hepatology 1998; 27:1191-9.
    • (1998) Hepatology , vol.27 , pp. 1191-1199
    • Bosch-Marcé, M.1    Morales-Ruiz, M.2    Jiménez, W.3
  • 90
    • 0030922914 scopus 로고    scopus 로고
    • Spontaneous bacterial peritonitis
    • Guarner C, Soriano G. Spontaneous bacterial peritonitis. Semin Liver Dis 1997; 17:203-17.
    • (1997) Semin Liver Dis , vol.17 , pp. 203-217
    • Guarner, C.1    Soriano, G.2
  • 91
    • 0002698278 scopus 로고    scopus 로고
    • Infections in liver disease
    • In: Bircher J, Benhamou JP, McIntyre N, Rizzetto M, Rodes J, eds., Oxford: Oxford University Press
    • Rimola A, Navasa M. Infections in liver disease. In: Bircher J, Benhamou JP, McIntyre N, Rizzetto M, Rodes J, eds. Oxford Textbook of Clinical Hepatology. Oxford: Oxford University Press, 1999; 1862-74.
    • (1999) Oxford Textbook of Clinical Hepatology , pp. 1862-1874
    • Rimola, A.1    Navasa, M.2
  • 92
    • 0031980857 scopus 로고    scopus 로고
    • Tumor necrosis factor and interleukin-6 in spontaneous bacterial peritonitis in cirrhosis: relationship with the development of renal impairment and mortality
    • Navasa M, Follo A, Filella X et al. Tumor necrosis factor and interleukin-6 in spontaneous bacterial peritonitis in cirrhosis: relationship with the development of renal impairment and mortality. Hepatology 1998; 27:1227-32.
    • (1998) Hepatology , vol.27 , pp. 1227-1232
    • Navasa, M.1    Follo, A.2    Filella, X.3
  • 93
    • 0035081881 scopus 로고    scopus 로고
    • Serum and ascitic fl uid nitrate levels in patients with cirrhosis
    • Coskun U, Ozenirler S, Sancak B, Bukan N. Serum and ascitic fl uid nitrate levels in patients with cirrhosis. Clin Chim Acta 2001; 306:127-32.
    • (2001) Clin Chim Acta , vol.306 , pp. 127-132
    • Coskun, U.1    Ozenirler, S.2    Sancak, B.3    Bukan, N.4
  • 94
    • 0030945861 scopus 로고    scopus 로고
    • Long-lasting NO overproduction in cirrhotic patients with spontaneous bacterial peritonitis
    • Bories PN, Campillo B, Azaou L, Scherman E. Long-lasting NO overproduction in cirrhotic patients with spontaneous bacterial peritonitis. Hepatology 1997; 25:1328-33.
    • (1997) Hepatology , vol.25 , pp. 1328-1333
    • Bories, P.N.1    Campillo, B.2    Azaou, L.3    Scherman, E.4
  • 95
    • 0032852648 scopus 로고    scopus 로고
    • Up-regulation of nitric oxide production by interferon-gamma in cultured peritoneal macrophages from patients with cirrhosis
    • Bories PN, Campillo B, Scherman E. Up-regulation of nitric oxide production by interferon-gamma in cultured peritoneal macrophages from patients with cirrhosis. Clin Sci (Lond) 1999; 97:399-406.
    • (1999) Clin Sci (Lond) , vol.97 , pp. 399-406
    • Bories, P.N.1    Campillo, B.2    Scherman, E.3
  • 96
    • 0030775671 scopus 로고    scopus 로고
    • Beta-adrenergic blockers and nitrovasodilators for the treatment of portal hypertension: the good, the bad, the ugly
    • Groszmann RJ. Beta-adrenergic blockers and nitrovasodilators for the treatment of portal hypertension: the good, the bad, the ugly. Gastroenterology 1997; 113:1794-7.
    • (1997) Gastroenterology , vol.113 , pp. 1794-1797
    • Groszmann, R.J.1
  • 97
    • 0035902558 scopus 로고    scopus 로고
    • NCX-1000, a NOreleasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension
    • Fiorucci S, Antonelli E, Morelli O et al. NCX-1000, a NOreleasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension. Proc Natl Acad Sci USA 2001; 98:8897-902.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8897-8902
    • Fiorucci, S.1    Antonelli, E.2    Morelli, O.3
  • 98
    • 0034121518 scopus 로고    scopus 로고
    • Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension
    • Yu Q, Shao R, Qian HS, George SE, Rockey DC. Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension. J Clin Invest 2000; 105:741-8.
    • (2000) J Clin Invest , vol.105 , pp. 741-748
    • Yu, Q.1    Shao, R.2    Qian, H.S.3    George, S.E.4    Rockey, D.C.5
  • 99
    • 0036719232 scopus 로고    scopus 로고
    • Vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats
    • Van de Casteele M, Omasta A, Janssens S et al. In vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats. Gut 2002; 51:440-5.
    • (2002) Gut , vol.51 , pp. 440-445
    • Van de Casteele, M.1    Omasta, A.2    Janssens, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.