Regulation of hepatic eNOS by caveolin and calmodulin after bile duct ligation in rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 280, Issue 6 43-6, 2001, Pages

  Shah, Vijay ^a   Cao, Sheng ^a   Hendrickson, Helen ^a   Yao, Janet ^a   Katusic, Zvonimir S ^a  

^a MAYO CLINIC   (United States)

Author keywords

Cholesterol; Endothelial nitric oxide synthase; Portal hypertension; Protein interactions

Indexed keywords

CALMODULIN; CAVEOLIN; CAVEOLIN 1; CHOLESTEROL; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; BINDING COMPETITION; CELLULAR DISTRIBUTION; CHOLESTASIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME REGULATION; IMMUNOPEROXIDASE STAINING; LIVER CIRRHOSIS; MALE; NONHUMAN; PORTAL HYPERTENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VASODILATATION; WESTERN BLOTTING;

EID: 0034973581     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2001.280.6.g1209     Document Type: Article

References (34)

1. Nonuniformity of endothelial constitutive nitric oxide synthase distribution in cardiac endothelium
2. ET-1 induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action
3. Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol
4. Caveolin-1 in normal and human cirrhotic liver
5. Hypercholesterolemia decreases nitric oxide production by promoting the interactions of caveolin and endothelial nitric oxide synthase
6. Dynamic regulation of endothelial nitric oxide synthase: Complementary roles of dual acylation and caveolin interactions
7. The endothelial nitric-oxide synthase-caveolin regulatory cycle
8. Intracellular cholesterol transport
9. Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: Implications for nitric oxide signaling
10. Altered expression of caveolin-1 and increased cholesterol in detergent insoluble membrane fractions from liver in mice with Niemann-Pick disease type C
11. Reconstitution of an endothelial nitric oxide synthase, hsp 90, and caveolin-1 complex in vitro: Evidence that hsp 90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1
12. Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats
13. Regulation of caveolin and caveolae by cholesterol in MDCK cells
14. Endothelin-1 modulates intrahepatic resistance in a rat model of noncirrhotic portal hypertension
15. Plasma lipoprotein pattern in relation to liver histology after toxic hepatitis and experimental biliary obstruction in rabbits
16. Endothelin-1-induced vasoconstriction causes a significant increase in portal pressure of rat liver: Localized constrictive effect on the distal segment of preterminal portal venules as revealed by light and electron microscopy and serial reconstruction
17. Isolation and characterization of Kupffer and endothelial cells from the rat liver
18. Fat-storing cells of the rat liver: Their isolation and purification
19. VIP21, a 21-kD membrane protein is an integral component of trans-golgi-network-derived transport vesicles
20. Lipoic acid prevents development of the hyperdynamic circulation in anesthetized rats with biliary cirrhosis
21. 2+-calmodulin and caveolin
22. Caveolin versus calmodulin. Counterbalancing allosteric modulators of endothelial nitric oxide synthase
23. Dynamin at the neck of caveolae mediates their budding to form transport vesicles by GTP-driven fission from the plasma membrane of endothelium
24. Molecular control of nitric oxide synthases in the cardiovascular system
25. The "early-sorting" endocytic compartment of rat hepatocytes is involved in the intracellular pathway of caveolin-1 (VIP-21)
26. Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility
27. Regulation of inducible nitric oxide synthase and nitric oxide during hepatic injury and fibrogenesis
28. Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: Endothelial dysfunction in portal hypertension
29. Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo
30. Gene transfer of recombinant endothelial nitric oxide synthase to liver in vivo and in vitro
31. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of hepatic resistance
32. Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental liver cirrhosis
33. Caveolins, liquid-ordered domains, and signal transduction
34. Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes