Up regulation of nitric oxide production by interferon-γ in cultured peritoneal macrophages from patients with cirrhosis

Clinical Science

Volumn 97, Issue 4, 1999, Pages 399-406

  Bories, P N ^a   Campillo, B ^a   Scherman, E ^a  

^a Hopital Albert Chenevier   (France)

Author keywords

Diaphorase activity; Immunoperoxidase cytochemistry; Inducible NO synthase; Protein expression; Western blot analysis

Indexed keywords

GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ADULT; AGED; ARTICLE; ASCITES FLUID; BACTERIAL PERITONITIS; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LIVER CIRRHOSIS; MALE; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASODILATATION;

ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; INTERFERON-GAMMA, RECOMBINANT; LIVER CIRRHOSIS, ALCOHOLIC; MACROPHAGES, PERITONEAL; MALE; MIDDLE AGED; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; UP-REGULATION;

EID: 0032852648     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS19980415     Document Type: Article

References (29)

1. 1 Nathan, C. (1992) Nitric oxide as a secretory product of mammalian cells. FASEB J. 6, 3051-3064
2. 2 Nussler, A. K., Di Silvio, M., Billiar, T. R. et al. (1992) Stimulation of the nitric oxide synthase pathway in human hepatocytcs by cytokines and endotoxin. J. Exp. Med. 176, 261-264
3. 3 Palmer, R. M., Hickery, M. S., Charles, I. G., Moncada, S. and Bayliss, M. T. (1993) Induction of nitric oxide synthase in human chondrocytes. Biochem. Biophys. Res. Commun. 193, 398-405
4. 4 Denis, M. (1994) Human monocytes/macrophages: NO or no NO? J. Leukocyte Biol. 55, 682-684
5. 5 Weinberg, J. B. (1998) Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: a review. Mol. Med. 4, 557-591
6. 6 Sogni, P., Garnier, P., Gadano, A. et al. (1995) Endogenous pulmonary nitric oxide production measured from exhaled air is increased in patients with severe cirrhosis. J. Hepatol. 23, 471-473
7. 7 Matsumoto, A., Ogura, K., Hirata, Y. et al. (1995) Increased nitric oxide in the exhaled air of patients with decompensated liver cirrhosis. Ann. Intern. Med. 123, 110-113
8. 8 Guarner, C., Soriano, G., Tomas, A. et al. (1993) Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to enclotoxemia. Hepatology 18, 1139-1143
9. 9 Bird, G., Severn, A., Danesh, B. J. and Liew, F. Y. (1993) Nitric oxide in alcohol-induced liver failure. J. Hepatol. 19, 316-317
10. 10 Campillo, B., Bories, P. N., Benvenutti, C. and Dupeyron, C. (1996) Serum and urinary nitrate levels in liver cirrhosis: relationship with endotoxemia, renal function and hyperdynamic circulation. J. Hepatol. 24, 707-714
11. 11 Campillo, B., Chabrier, P. E., Pelle, G. et al. (1995) Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis. Hepatology 22, 1423-1429
12. 12 Bories, P. N., Campillo, B., Azaou, L. and Scherman, E. (1997) Long-lasting NO overproduction in cirrhotic patients with spontaneous bacterial peritonitis. Hepatology 25, 1328-1333
13. 13 Hope, B. T., Michael, G. J., Knigge, K. M. and Vincent, S. R. (1991) Neuronal NADPH diaphorase is a nitric oxide synthase. Proc. Natl, Acad. Sci. U.S.A. 88, 2811-2814
14. 14 Dawson, T. M., Bredt, D. S., Fotuhi, J., Hwang, P. M. and Snyder, S. H. (1991) Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc. Natl. Acad. Sci. U.S.A. 88, 7797-7801
15. 15 Pugh, R. N. H., Murray-Lyon, I. M., Dawson, J. L., Piectroni, M. C. and Williams, R. (1973) Transsection of the oesophagus for bleeding oesophageal varices. Br. J. Surg. 60, 646-649
16. 16 Bories, P. N. and Bories, C. (1995) Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase. Clin. Chem. 41, 904-907
17. 17 Nicholson, S., Bonecini-Almeida, M. G., Lapa e Silva, J. R. et al. (1996) Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis. J. Exp. Med. 183, 2293-2302
18. 18 Nichols, K., Staines, W. and Krantis, A, (1993) Nitric oxide synthase distribution in the rat intestine: a histochemical analysis. Gastroenterology 105, 1651-1661
19. 19 Morales-Ruiz, M., Jimenez, W., Ros, J. et al. (1997) Nitric oxide production by peritoneal macrophages of cirrhotic rats: a host response against bacterial peritonitis. Gastroenterology 112, 2056-2064
20. 20 Severn, A., Xu, D., Doyle, J. et la. (1993) Pre-exposure of murine macrophages to lipopolysaccharide inhibits the induction of nitric oxide synthase and reduces leishmanicidal activity. Eur. J. Immunol. 23, 1711-1714
21. 21 Bogdan, C., Vodovotz, Y., Paik, J., Xie, Q. W. and Nathan, C. (1993) Traces of bacterial lipopolysaccharide suppress IFN-gamma-induced nitric oxide synthase gene expression in primary mouse macrophages. J. Immunol. 151, 301-309
22. 22 Vodovotz, Y., Kwon, N. S., Pospischil, M., Manning, J., Paik, J. and Nathan, C. (1994) Inactivation of nitric oxide synthase after prolonged incubation of mouse macrophages with IFN-gamma and bacterial lipopolysaccharide. J. Immunol. 152, 4110-4118
23. 23 Weinberg, J. B., Misukonis, M. A., Shami, P. J. et al. (1995) Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages. Blood 86, 1184-1195
24. 24 St. Clair, E. W., Wilkinson, W. E., Lang, T. et al. (1996) Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients. J. Exp. Med. 184, 1173-1178
25. 25 Sakurai, H., Kohsaka, H., Liu, M. F. et al. (1995) Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides. J. Clin. Invest. 96, 2357-2363
26. 26 Nunokawa, Y., Oikawa, S. and Tanaka, S. (1996) Human inducible nitric oxide synthase gene is transcriptionally regulated by nuclear factor-KB dependent mechanism. Biochem. Biophys. Res. Commun. 223, 347-352
27. 27 Denis, M. (1991) Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium. J. Leukocyte Biol. 49, 380-387
28. 28 Stenger, S., Thuring, H., Rollinghoff, M. and Bogdan, C. (1994) Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J. Exp. Med. 180, 783-793
29. 29 Norris, K. A., Schrimpf, J. E., Flynn, J. and Morris, S. M. (1995) Enhancement of macrophage microbicidal activity: supplemental arginine and citrulline augment nitric oxide production in murine peritoneal macrophages and promote intracellular killing of Trypanosoma cruzi. Infect. Immun. 63, 2793-2796