메뉴 건너뛰기




Volumn 284, Issue 4, 2010, Pages 231-242

Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae

Author keywords

DNA integration; Recombination; Target sites; Ty

Indexed keywords

COMPLEMENTARY DNA; DNA FRAGMENT; INTEGRASE; PROTEIN TY1; UNCLASSIFIED DRUG; FUNGAL DNA; FUNGAL RNA; PRIMER DNA; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE;

EID: 78049443006     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-010-0561-4     Document Type: Review
Times cited : (10)

References (48)
  • 1
    • 3543090451 scopus 로고    scopus 로고
    • Local definition of Ty1 target preference by long terminal repeats and clustered tRNA genes
    • Bachman N, Eby Y, Boeke JD (2004) Local definition of Ty1 target preference by long terminal repeats and clustered tRNA genes. Genome Res 14:1232-1247
    • (2004) Genome Res , vol.14 , pp. 1232-1247
    • Bachman, N.1    Eby, Y.2    Boeke, J.D.3
  • 2
    • 0037318210 scopus 로고    scopus 로고
    • Transcriptional interactions between yeast tRNA genes, flanking genes and Ty elements: A genomic point of view
    • Bolton EC, Boeke JD (2003) Transcriptional interactions between yeast tRNA genes, flanking genes and Ty elements: A genomic point of view. Genome Res 13:254-263
    • (2003) Genome Res , vol.13 , pp. 254-263
    • Bolton, E.C.1    Boeke, J.D.2
  • 3
    • 0034796243 scopus 로고    scopus 로고
    • Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing
    • Bond AT, Mangus DA, He F, Jacobson A (2001) Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing. Mol Cell Biol 21:7366-7379
    • (2001) Mol Cell Biol , vol.21 , pp. 7366-7379
    • Bond, A.T.1    Mangus, D.A.2    He, F.3    Jacobson, A.4
  • 4
    • 0028133405 scopus 로고
    • Ty1 in vitro integration: Effects of mutations in cis and trans
    • Braiterman LT, Boeke JD (1994) Ty1 in vitro integration: Effects of mutations in cis and trans. Mol Cell Biol 14:5731-5740
    • (1994) Mol Cell Biol , vol.14 , pp. 5731-5740
    • Braiterman, L.T.1    Boeke, J.D.2
  • 5
    • 0029977163 scopus 로고    scopus 로고
    • Expression of functional HIV-1 integrase in the yeast Saccharomyces cerevisiae leads to the emergence of a lethal phenotype: Potential use for inhibitor screening
    • Caumont AB, Jamieson GA, Pichuantes S, Nguyen AT, Litvak S, Dupont C (1996) Expression of functional HIV-1 integrase in the yeast Saccharomyces cerevisiae leads to the emergence of a lethal phenotype: Potential use for inhibitor screening. Curr Genet 29:503-510
    • (1996) Curr Genet , vol.29 , pp. 503-510
    • Caumont, A.B.1    Jamieson, G.A.2    Pichuantes, S.3    Nguyen, A.T.4    Litvak, S.5    Dupont, C.6
  • 6
    • 34548585254 scopus 로고    scopus 로고
    • Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae
    • Chan CY, Kiechle M, Manivasakam P, Schiestl RH (2007) Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae. Nucleic Acids Res 35:5051-5059
    • (2007) Nucleic Acids Res , vol.35 , pp. 5051-5059
    • Chan, C.Y.1    Kiechle, M.2    Manivasakam, P.3    Schiestl, R.H.4
  • 7
    • 0029879536 scopus 로고    scopus 로고
    • Integration of the yeast retrotransposon Ty1 is targeted to regions upstream of genes transcribed by RNA polymerase III
    • Devine SE, Boeke JD (1996) Integration of the yeast retrotransposon Ty1 is targeted to regions upstream of genes transcribed by RNA polymerase III. Genes Dev 10:620-633
    • (1996) Genes Dev , vol.10 , pp. 620-633
    • Devine, S.E.1    Boeke, J.D.2
  • 8
    • 0032792105 scopus 로고    scopus 로고
    • Involvement of DNA end-binding protein Ku in Ty element retrotransposition
    • Downs JA, Jackson SP (1999) Involvement of DNA end-binding protein Ku in Ty element retrotransposition. Mol Cell Biol 19:6260-6268
    • (1999) Mol Cell Biol , vol.19 , pp. 6260-6268
    • Downs, J.A.1    Jackson, S.P.2
  • 9
    • 2342565902 scopus 로고    scopus 로고
    • A means to a DNA end: The many roles of Ku
    • Downs JA, Jackson SP (2004) A means to a DNA end: The many roles of Ku. Nat Rev Mol Cell Biol 5:367-378
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 367-378
    • Downs, J.A.1    Jackson, S.P.2
  • 10
    • 0025218956 scopus 로고
    • A specific terminal structure is required for Ty1 transposition
    • Eichinger DJ, Boeke JD (1990) A specific terminal structure is required for Ty1 transposition. Genes Dev 4:324-330
    • (1990) Genes Dev , vol.4 , pp. 324-330
    • Eichinger, D.J.1    Boeke, J.D.2
  • 11
    • 0027288231 scopus 로고
    • A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae
    • Feldmann H, Winnacker EL (1993) A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae. J Biol Chem 268:12895-12900
    • (1993) J Biol Chem , vol.268 , pp. 12895-12900
    • Feldmann, H.1    Winnacker, E.L.2
  • 12
    • 0036864626 scopus 로고    scopus 로고
    • Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
    • Frank-Vaillant M, Marcand S (2002) Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination. Mol Cell 10:1189-1199
    • (2002) Mol Cell , vol.10 , pp. 1189-1199
    • Frank-Vaillant, M.1    Marcand, S.2
  • 13
    • 33746951472 scopus 로고    scopus 로고
    • Ku and the stability of the genome
    • Friedl AA (2002) Ku and the Stability of the Genome. J Biomed Biotechnol 2:61-65
    • (2002) J Biomed Biotechnol , vol.2 , pp. 61-65
    • Friedl, A.A.1
  • 14
    • 0031825679 scopus 로고    scopus 로고
    • Effects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cells
    • Galli A, Schiestl RH (1998) Effects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cells. Genetics 149:1235-1250
    • (1998) Genetics , vol.149 , pp. 1235-1250
    • Galli, A.1    Schiestl, R.H.2
  • 15
    • 0026055399 scopus 로고
    • Proteolytic processing of pol TYB proteins from the yeast retrotransposon Ty1
    • Garfinkel DJ, Hedge AM, Youngren SD, Copeland TD (1991) Proteolytic processing of pol TYB proteins from the yeast retrotransposon Ty1. J Virol 65:4573-4581
    • (1991) J Virol , vol.65 , pp. 4573-4581
    • Garfinkel, D.J.1    Hedge, A.M.2    Youngren, S.D.3    Copeland, T.D.4
  • 16
    • 0024266139 scopus 로고
    • New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
    • Gietz RD, Sugino A (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534
    • (1988) Gene , vol.74 , pp. 527-534
    • Gietz, R.D.1    Sugino, A.2
  • 17
    • 0026562884 scopus 로고
    • Improved method for high efficiency transformation on intact yeast cells
    • Gietz RD, St. Jean A, Woods RA, Schiestl RH (1992) Improved method for high efficiency transformation on intact yeast cells. Nucleic Acids Res 20:1425
    • (1992) Nucleic Acids Res , vol.20 , pp. 1425
    • Gietz, R.D.1    St. Jean, A.2    Woods, R.A.3    Schiestl, R.H.4
  • 18
    • 0033924953 scopus 로고    scopus 로고
    • Identifying tagged transposon insertion sites in yeast by direct genomic sequencing
    • Horecka J, Jigami Y (2000) Identifying tagged transposon insertion sites in yeast by direct genomic sequencing. Yeast 16:967-970
    • (2000) Yeast , vol.16 , pp. 967-970
    • Horecka, J.1    Jigami, Y.2
  • 19
    • 0027192351 scopus 로고
    • Hotspots for unselected Ty1 transposition events on yeast chromosome III are near tRNA genes and LTR sequences
    • Ji H, Moore DP, Blomberg MA, Braiterman LT, Voytas DF, Natsoulis G, Boeke JD (1993) Hotspots for unselected Ty1 transposition events on yeast chromosome III are near tRNA genes and LTR sequences. Cell 73:1007-1018
    • (1993) Cell , vol.73 , pp. 1007-1018
    • Ji, H.1    Moore, D.P.2    Blomberg, M.A.3    Braiterman, L.T.4    Voytas, D.F.5    Natsoulis, G.6    Boeke, J.D.7
  • 20
    • 0031883282 scopus 로고    scopus 로고
    • Invading the yeast nucleus: A nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo
    • Kenna MA, Brachmann CB, Devine SE, Boeke JD (1998) Invading the yeast nucleus: A nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo. Mol Cell Biol 18:1115-1124
    • (1998) Mol Cell Biol , vol.18 , pp. 1115-1124
    • Kenna, M.A.1    Brachmann, C.B.2    Devine, S.E.3    Boeke, J.D.4
  • 23
    • 0031832807 scopus 로고    scopus 로고
    • Transposable elements and genome organization: A comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence
    • Kim JM, Vanguri S, Boeke JD, Gabriel A, Voytas DF (1998) Transposable elements and genome organization: A comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res 8:464-478
    • (1998) Genome Res , vol.8 , pp. 464-478
    • Kim, J.M.1    Vanguri, S.2    Boeke, J.D.3    Gabriel, A.4    Voytas, D.F.5
  • 24
    • 16244382514 scopus 로고    scopus 로고
    • The Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair
    • Koike M, Koike A (2005) The Ku70-binding site of Ku80 is required for the stabilization of Ku70 in the cytoplasm, for the nuclear translocation of Ku80, and for Ku80-dependent DNA repair. Exp Cell Res 305:266-276
    • (2005) Exp Cell Res , vol.305 , pp. 266-276
    • Koike, M.1    Koike, A.2
  • 25
    • 0030776187 scopus 로고    scopus 로고
    • Plus-strand strong-stop DNA transfer in yeast Ty retrotransposons
    • Lauermann V, Boeke JD (1997) Plus-strand strong-stop DNA transfer in yeast Ty retrotransposons. EMBO J 16:6603-6612
    • (1997) EMBO J , vol.16 , pp. 6603-6612
    • Lauermann, V.1    Boeke, J.D.2
  • 26
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee SE, Moore JK, Holmes A, Umezu K, Kolodner RD, Haber JE (1998) Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94:399-409
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 27
    • 18944382213 scopus 로고    scopus 로고
    • Happy together: The life and times of Ty retrotransposons and their hosts
    • Lesage P, Todeschini AL (2005) Happy together: The life and times of Ty retrotransposons and their hosts. Cytogenet Genome Res 110:70-90
    • (2005) Cytogenet Genome Res , vol.110 , pp. 70-90
    • Lesage, P.1    Todeschini, A.L.2
  • 28
    • 0031888689 scopus 로고    scopus 로고
    • Nonhomologous end-joining during restriction enzyme-mediated DNA integration in Saccha-romyces cerevisiae
    • Manivasakam P, Schiestl RH (1998) Nonhomologous end-joining during restriction enzyme-mediated DNA integration in Saccha-romyces cerevisiae. Mol Cell Biol 18:1736-1745
    • (1998) Mol Cell Biol , vol.18 , pp. 1736-1745
    • Manivasakam, P.1    Schiestl, R.H.2
  • 29
    • 0035172108 scopus 로고    scopus 로고
    • Ty1 proteolytic cleavage sites are required for transposition: All sites are not created equal
    • Merkulov GV, Lawler JF, Eby Y, Boeke JD (2001) Ty1 proteolytic cleavage sites are required for transposition: All sites are not created equal. J Virol 75:638-644
    • (2001) J Virol , vol.75 , pp. 638-644
    • Merkulov, G.V.1    Lawler, J.F.2    Eby, Y.3    Boeke, J.D.4
  • 30
    • 12544250956 scopus 로고    scopus 로고
    • Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening
    • Minic J, Persuy MA, Godel E, Aioun J, Connerton I, Salesse R, Pajot-Augy E (2005) Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening. FEBS J 272:524-537
    • (2005) FEBS J , vol.272 , pp. 524-537
    • Minic, J.1    Persuy, M.A.2    Godel, E.3    Aioun, J.4    Connerton, I.5    Salesse, R.6    Pajot-Augy, E.7
  • 31
    • 0028201743 scopus 로고
    • Expression and partial purification of enzymatically active recombinant Ty1 integrase in Saccharo-myces cerevisiae
    • Moore SP, Garfinkel DJ (1994) Expression and partial purification of enzymatically active recombinant Ty1 integrase in Saccharo-myces cerevisiae. Proc Natl Acad Sci USA 91:1843-1847
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1843-1847
    • Moore, S.P.1    Garfinkel, D.J.2
  • 32
    • 0034468810 scopus 로고    scopus 로고
    • Correct integration of model substrates by Ty1 integrase
    • Moore SP, Garfinkel DJ (2000) Correct integration of model substrates by Ty1 integrase. J Virol 74:11522-11530
    • (2000) J Virol , vol.74 , pp. 11522-11530
    • Moore, S.P.1    Garfinkel, D.J.2
  • 33
    • 0029023845 scopus 로고
    • Substrate specificity of Ty1 integrase
    • Moore SP, Powers M, Garfinkel DJ (1995) Substrate specificity of Ty1 integrase. J Virol 69:4683-4692
    • (1995) J Virol , vol.69 , pp. 4683-4692
    • Moore, S.P.1    Powers, M.2    Garfinkel, D.J.3
  • 34
    • 0031883281 scopus 로고    scopus 로고
    • A Ty1 integrase nuclear localization signal required for retrotransposition
    • Moore SP, Rinckel LA, Garfinkel DJ (1998) A Ty1 integrase nuclear localization signal required for retrotransposition. Mol Cell Biol 18:1105-1114
    • (1998) Mol Cell Biol , vol.18 , pp. 1105-1114
    • Moore, S.P.1    Rinckel, L.A.2    Garfinkel, D.J.3
  • 35
    • 0031878384 scopus 로고    scopus 로고
    • In vivo Ty1 reverse transcription can generate replication intermediates with untidy ends
    • Mules EH, Uzun O, Gabriel A (1998) In vivo Ty1 reverse transcription can generate replication intermediates with untidy ends. J Virol 72:6490-6503
    • (1998) J Virol , vol.72 , pp. 6490-6503
    • Mules, E.H.1    Uzun, O.2    Gabriel, A.3
  • 37
    • 0034733594 scopus 로고    scopus 로고
    • The yeast Ty virus-like particles
    • Roth JF (2000) The yeast Ty virus-like particles. Yeast 16:785-795
    • (2000) Yeast , vol.16 , pp. 785-795
    • Roth, J.F.1
  • 38
    • 0025777047 scopus 로고
    • Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae
    • Schiestl RH, Petes TD (1991) Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 88:7585-7589
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7585-7589
    • Schiestl, R.H.1    Petes, T.D.2
  • 39
    • 0027266927 scopus 로고
    • Transformation of Saccharomyces cerevisiae with nonhomologous DNA: Illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial sequences
    • Schiestl RH, Dominska M, Petes TD (1993) Transformation of Saccharomyces cerevisiae with nonhomologous DNA: Illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial sequences. Mol Cell Biol 13:2697-2705
    • (1993) Mol Cell Biol , vol.13 , pp. 2697-2705
    • Schiestl, R.H.1    Dominska, M.2    Petes, T.D.3
  • 40
    • 0028246091 scopus 로고
    • Effect of mutations in genes affecting homologous recombination on restriction-enzyme mediated and illegitimate recombination in Saccharomyces cerevisiae
    • Schiestl RH, Zhu J, Petes TD (1994) Effect of mutations in genes affecting homologous recombination on restriction-enzyme mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol Cell Biol 14:4493-4500
    • (1994) Mol Cell Biol , vol.14 , pp. 4493-4500
    • Schiestl, R.H.1    Zhu, J.2    Petes, T.D.3
  • 41
    • 0027939848 scopus 로고
    • Efficient homologous recombination of Ty1 element cDNA when integration is blocked
    • Sharon G, Burkett TJ, Garfinkel DJ (1994) Efficient homologous recombination of Ty1 element cDNA when integration is blocked. Mol Cell Biol 14:6540-6551
    • (1994) Mol Cell Biol , vol.14 , pp. 6540-6551
    • Sharon, G.1    Burkett, T.J.2    Garfinkel, D.J.3
  • 43
    • 23844479763 scopus 로고    scopus 로고
    • Yeast system as a model to study Moloney murine leukemia virus integrase: Expression, mutagenesis and search for eukaryotic partners
    • Vera J, Parissi V, Garcia A, Zuniga R, Andreola ML, Caumont-Sarcos A, Tarrago-Litvak L, Leon O (2005) Yeast system as a model to study Moloney murine leukemia virus integrase: Expression, mutagenesis and search for eukaryotic partners. J Gen Virol 86:2481-2488
    • (2005) J Gen Virol , vol.86 , pp. 2481-2488
    • Vera, J.1    Parissi, V.2    Garcia, A.3    Zuniga, R.4    Andreola, M.L.5    Caumont-Sarcos, A.6    Tarrago-Litvak, L.7    Leon, O.8
  • 44
    • 33750349866 scopus 로고    scopus 로고
    • Cooperation between reverse transcriptase and integrase during reverse transcription and formation of the preintegrative complex of Ty1
    • Wilhelm M, Wilhelm FX (2006) Cooperation between reverse transcriptase and integrase during reverse transcription and formation of the preintegrative complex of Ty1. Eukaryotic Cell 5:1760-1769
    • (2006) Eukaryotic Cell , vol.5 , pp. 1760-1769
    • Wilhelm, M.1    Wilhelm, F.X.2
  • 45
    • 0033486025 scopus 로고    scopus 로고
    • A sequence immediately upstream of the plus-strand primer is essential for plus-strand synthesis of the Saccharomyces cere-visiae Ty1 retrotransposon
    • Wilhelm M, Heyman T, Boutabout M, Wilhelm FX (1999) A sequence immediately upstream of the plus-strand primer is essential for plus-strand synthesis of the Saccharomyces cere-visiae Ty1 retrotransposon. Nucleic Acids Res 27:4547-4552
    • (1999) Nucleic Acids Res , vol.27 , pp. 4547-4552
    • Wilhelm, M.1    Heyman, T.2    Boutabout, M.3    Wilhelm, F.X.4
  • 46
    • 23844526483 scopus 로고    scopus 로고
    • Reverse transcriptase and integrase of the Saccharomyces cerevisiae Ty1 element
    • DOI 10.1159/000084960
    • Wilhelm FX, Wilhelm M, Gabriel A (2005) Reverse transcriptase and integrase of the Saccharomyces cerevisiae Ty1 element. Cytogenet Genome Res 110:269-287 (Pubitemid 41159905)
    • (2005) Cytogenetic and Genome Research , vol.110 , Issue.1-4 , pp. 269-287
    • Wilhelm, F.-X.1    Wilhelm, M.2    Gabriel, A.3
  • 47
    • 0028806426 scopus 로고
    • Nature of abortive transformation in Saccharomyces cerevisiae
    • Yap WY, Schiestl RH (1995) Nature of abortive transformation in Saccharomyces cerevisiae. Curr Genet 28:517-520
    • (1995) Curr Genet , vol.28 , pp. 517-520
    • Yap, W.Y.1    Schiestl, R.H.2
  • 48
    • 0029960067 scopus 로고    scopus 로고
    • Topoisomerase i involvement in illegitimate recombination in Saccharomyces cerevisiae
    • Zhu J, Schiestl RH (1996) Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae. Mol Cell Biol 16:1805-1812
    • (1996) Mol Cell Biol , vol.16 , pp. 1805-1812
    • Zhu, J.1    Schiestl, R.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.