Expression of functional HIV-1 integrase in the yeast Saccharomyces cerevisiae leads to the emergence of a lethal phenotype: Potential use for inhibitor screening

Current Genetics

Volumn 29, Issue 6, 1996, Pages 503-510

  Caumont, Anne B ^a   Jamieson, Gordon A ^a   Pichuantes, Sergio ^b   Nguyen, Anton Tien ^b   Litvak, Simon ^a   Dupont, Charles Henri ^a  

^a Institut de Biochimie et Genetique Cellulaires   (France)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

AIDS; HIV 1; Integrase; Yeast

Indexed keywords

DNA; ENZYME INHIBITOR; GLUCOSE; INTEGRASE; VIRUS ENZYME;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME SYNTHESIS; EXPRESSION VECTOR; GENE DISRUPTION; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS 1; LETHALITY; MISSENSE MUTATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECOMBINANT GENE; SACCHAROMYCES CEREVISIAE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE VIRUS L-A (L1);

EID: 0029977163     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02426953     Document Type: Article

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