Critical Functions of Rpa3/Ssb3 in S-Phase DNA Damage Responses in Fission Yeast

PLoS Genetics

Volumn 6, Issue 9, 2010, Pages

  Cavero, Santiago ^a,b   Limbo, Oliver ^a   Russell, Paul ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MESYLIC ACID METHYL ESTER; NUCLEIC ACID BINDING PROTEIN; RAD11 PROTEIN; RAD22 PROTEIN; REPLICATION FACTOR A; REPLICATION PROTEIN A3; SINGLE STRANDED DNA BINDING PROTEIN; SINGLE STRANDED DNA BINDING PROTEIN 3; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CELL CYCLE S PHASE; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GENE DISRUPTION; GENE INTERACTION; HOLLIDAY JUNCTION; INTRACELLULAR SIGNALING; MEIOSIS; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SCHIZOSACCHAROMYCES POMBE;

SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

EID: 78049416983     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1001138     Document Type: Article

References (48)

1. Binz SK, Sheehan AM, Wold MS (2004) Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair 3: 1015-1024.
2. Richard DJ, Bolderson E, Khanna KK (2009) Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis. Crit Rev Biochem Mol Biol. pp 1-19.
3. Wold MS (1997) Replication protein A: a heterotrimeric, single-stranded DNAbinding protein required for eukaryotic DNA metabolism. Annu Rev Biochem 66: 61-92.
4. Iftode C, Daniely Y, Borowiec JA (1999) Replication protein A (RPA): the eukaryotic SSB. Crit Rev Biochem Mol Biol 34: 141-180.
5. Wobbe CR, Weissbach L, Borowiec JA, Dean FB, Murakami Y, et al. (1987) Replication of simian virus 40 origin-containing DNA in vitro with purified proteins. Proc Natl Acad Sci U S A 84: 1834-1838.
6. Fairman MP, Stillman B (1988) Cellular factors required for multiple stages of SV40 DNA replication in vitro. EMBO J 7: 1211-1218.
7. Wold MS, Kelly T (1988) Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA. Proc Natl Acad Sci U S A 85: 2523-2527.
8. He Z, Henricksen LA, Wold MS, Ingles CJ (1995) RPA involvement in the damage-recognition and incision steps of nucleotide excision repair. Nature 374: 566-569.
9. Lin YL, Shivji MK, Chen C, Kolodner R, Wood RD, et al. (1998) The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair. J Biol Chem 273: 1453-1461.
10. Bastin-Shanower SA, Brill SJ (2001) Functional analysis of the four DNA binding domains of replication protein A. The role of RPA2 in ssDNA binding. J Biol Chem 276: 36446-36453.
11. Bochkarev A, Bochkareva E (2004) From RPA to BRCA2: lessons from singlestranded DNA binding by the OB-fold. Curr Opin Struct Biol 14: 36-42.
12. Henricksen LA, Umbricht CB, Wold MS (1994) Recombinant replication protein A: expression, complex formation, and functional characterization. J Biol Chem 269: 11121-11132.
13. Stigger E, Dean FB, Hurwitz J, Lee SH (1994) Reconstitution of functional human single-stranded DNA-binding protein from individual subunits expressed by recombinant baculoviruses. Proc Natl Acad Sci U S A 91: 579-583.
14. Brill SJ, Stillman B (1991) Replication factor-A from Saccharomyces cerevisiae is encoded by three essential genes coordinately expressed at S phase. Genes Dev 5: 1589-1600.
15. Zou L, Elledge SJ (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300: 1542-1548.
16. Ball HL, Ehrhardt MR, Mordes DA, Glick GG, Chazin WJ, et al. (2007) Function of a conserved checkpoint recruitment domain in ATRIP proteins. Mol Cell Biol 27: 3367-3377.
17. Maniar HS, Wilson R, Brill SJ (1997) Roles of replication protein-A subunits 2 and 3 in DNA replication fork movement in Saccharomyces cerevisiae. Genetics 145: 891-902.
18. Pommier Y (2006) Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 6: 789-802.
19. Koster DA, Palle K, Bot ES, Bjornsti MA, Dekker NH (2007) Antitumour drugs impede DNA uncoiling by topoisomerase I. Nature 448: 213-217.
20. Roseaulin L, Yamada Y, Tsutsui Y, Russell P, Iwasaki H, et al. (2008) Mus81 is essential for sister chromatid recombination at broken replication forks. Embo J 27: 1378-1387.
21. Boddy MN, Gaillard PH, McDonald WH, Shanahan P, Yates JR, 3rd, et al. (2001) Mus81-Eme1 are essential components of a Holliday junction resolvase. Cell 107: 537-548.
22. Boddy MN, Lopez-Girona A, Shanahan P, Interthal H, Heyer WD, et al. (2000) Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1. Mol Cell Biol 20: 8758-8766.
23. Doe CL, Ahn JS, Dixon J, Whitby MC (2002) Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks. J Biol Chem 277: 32753-32759.
24. Yokoyama M, Inoue H, Ishii C, Murakami Y (2007) The novel gene mus7+ is involved in the repair of replication-associated DNA damage in fission yeast. DNA Repair 6: 770-780.
25. Dovey CL, Russell P (2007) Mms22 preserves genomic integrity during DNA replication in Schizosaccharomyces pombe. Genetics 177: 47-61.
26. Duro E, Vaisica JA, Brown GW, Rouse J (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair 7: 811-818.
27. Zaidi IW, Rabut G, Poveda A, Scheel H, Malmstrom J, et al. (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9: 1034-1040.
28. Dovey CL, Aslanian A, Sofueva S, Yates JR, 3rd, Russell P (2009) Mms1- Mms22 complex protects genome integrity in Schizosaccharomyces pombe. DNA Repair 8: 1390-1399.
29. Deshpande GP, Hayles J, Hoe KL, Kim DU, Park HO, et al. (2009) Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance. DNA Repair 8: 672-679.
30. Parker AE, Clyne RK, Carr AM, Kelly TJ (1997) The Schizosaccharomyces pombe rad11+ gene encodes the large subunit of replication protein A. Mol Cell Biol 17: 2381-2390.
31. Smith GR, Boddy MN, Shanahan P, Russell P (2003) Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion. Genetics 165: 2289-2293.
32. Rhind N, Russell P (2000) Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways. J Cell Sci 113: 3889-3896.
33. Walworth NC, Bernards R (1996) rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science 271: 353-356.
34. Noguchi E, Noguchi C, Du LL, Russell P (2003) Swi1 prevents replication fork collapse and controls checkpoint kinase Cds1. Mol Cell Biol 23: 7861-7874.
35. Meister P, Poidevin M, Francesconi S, Tratner I, Zarzov P, et al. (2003) Nuclear factories for signalling and repairing DNA double strand breaks in living fission yeast. Nucleic Acids Res 31: 5064-5073.
36. Du LL, Nakamura TM, Moser BA, Russell P (2003) Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes. Mol Cell Biol 23: 6150-6158.
37. Noguchi E, Noguchi C, McDonald WH, Yates JR, 3rd, Russell P (2004) Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol 24: 8342-8355.
38. Ansbach AB, Noguchi C, Klansek IW, Heidlebaugh M, Nakamura TM, et al. (2008) RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe. Mol Biol Cell 19: 595-607.
39. Shimada M, Okuzaki D, Tanaka S, Tougan T, Tamai KK, et al. (1999) Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints. Mol Biol Cell 10: 3991-4003.
40. Khasanov FK, Savchenko GV, Bashkirova EV, Korolev VG, Heyer WD, et al. (1999) A new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli RecA. Genetics 152: 1557-1572.
41. Sheedy DM, Dimitrova D, Rankin JK, Bass KL, Lee KM, et al. (2005) Brc1- mediated DNA repair and damage tolerance. Genetics 171: 457-468.
42. Williams JS, Williams RS, Dovey CL, Guenther G, Tainer JA, et al. (2010) gammaH2A binds Brc1 to maintain genome integrity during S-phase. EMBO J 29: 1136-1148.
43. Gaillard PH, Noguchi E, Shanahan P, Russell P (2003) The endogenous Mus81- Eme1 complex resolves Holliday junctions by a nick and counternick mechanism. Mol Cell 12: 747-759.
44. Cromie GA, Hyppa RW, Taylor AF, Zakharyevich K, Hunter N, et al. (2006) Single Holliday junctions are intermediates of meiotic recombination. Cell 127: 1167-1178.
45. Sung P (1997) Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes Dev 11: 1111-1121.
46. Akamatsu Y, Tsutsui Y, Morishita T, Siddique MS, Kurokawa Y, et al. (2007) Fission yeast Swi5/Sfr1 and Rhp55/Rhp57 differentially regulate Rhp51- dependent recombination outcomes. EMBO J 26: 1352-1362.
47. Kurokawa Y, Murayama Y, Haruta-Takahashi N, Urabe I, Iwasaki H (2008) Reconstitution of DNA strand exchange mediated by Rhp51 recombinase and two mediators. PLoS Biol 6: e88. doi:10.1371/journal.pbio.0060088.
48. Forsburg SL, Rhind N (2006) Basic methods for fission yeast. Yeast 23: 173-183.