-
1
-
-
0033933211
-
Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology
-
Kemink S.A., Hermus A.R., Swinkels L.M., Lutterman J.A., and Smals A.G. Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology. J Endocrinol Invest 23 (2000) 295-303
-
(2000)
J Endocrinol Invest
, vol.23
, pp. 295-303
-
-
Kemink, S.A.1
Hermus, A.R.2
Swinkels, L.M.3
Lutterman, J.A.4
Smals, A.G.5
-
2
-
-
0034095301
-
Correlations between bone mineral density and circulating bone metabolic markers in diabetic patients
-
Suzuki K., Sugimoto C., Takizawa M., et al. Correlations between bone mineral density and circulating bone metabolic markers in diabetic patients. Diabetes Res Clin Pract 48 (2000) 185-191
-
(2000)
Diabetes Res Clin Pract
, vol.48
, pp. 185-191
-
-
Suzuki, K.1
Sugimoto, C.2
Takizawa, M.3
-
3
-
-
23944490347
-
Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk
-
Vestergaard P., Rejnmark L., and Mosekilde L. Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk. Diabetologia 48 (2005) 1292-1299
-
(2005)
Diabetologia
, vol.48
, pp. 1292-1299
-
-
Vestergaard, P.1
Rejnmark, L.2
Mosekilde, L.3
-
4
-
-
44349112840
-
[Osteoporosis and fractures associated with drugs]
-
Vestergaard P., Rejnmark L., and Mosekilde L. [Osteoporosis and fractures associated with drugs]. Ugeskr Laeger 170 (2008) 1550-1555
-
(2008)
Ugeskr Laeger
, vol.170
, pp. 1550-1555
-
-
Vestergaard, P.1
Rejnmark, L.2
Mosekilde, L.3
-
5
-
-
0029848593
-
Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at adipocytes
-
Muller G., and Geisen K. Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at adipocytes. Horm Metab Res 28 (1996) 469-487
-
(1996)
Horm Metab Res
, vol.28
, pp. 469-487
-
-
Muller, G.1
Geisen, K.2
-
6
-
-
0029839173
-
Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at beta-cells
-
Kramer W., Muller G., and Geisen K. Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at beta-cells. Horm Metab Res 28 (1996) 464-468
-
(1996)
Horm Metab Res
, vol.28
, pp. 464-468
-
-
Kramer, W.1
Muller, G.2
Geisen, K.3
-
7
-
-
0034327237
-
The molecular mechanism of the insulin-mimetic/sensitizing activity of the antidiabetic sulfonylurea drug Amaryl
-
Muller G. The molecular mechanism of the insulin-mimetic/sensitizing activity of the antidiabetic sulfonylurea drug Amaryl. Mol Med 6 (2000) 907-933
-
(2000)
Mol Med
, vol.6
, pp. 907-933
-
-
Muller, G.1
-
8
-
-
0842291570
-
Phosphatidylinositol 3-kinase activation is required for sulfonylurea stimulation of glucose transport in rat skeletal muscle
-
Rodriguez E., Pulido N., Romero R., et al. Phosphatidylinositol 3-kinase activation is required for sulfonylurea stimulation of glucose transport in rat skeletal muscle. Endocrinology 145 (2004) 679-685
-
(2004)
Endocrinology
, vol.145
, pp. 679-685
-
-
Rodriguez, E.1
Pulido, N.2
Romero, R.3
-
9
-
-
0035807926
-
Insulin-mimetic signaling by the sulfonylurea glimepiride and phosphoinositolglycans involves distinct mechanisms for redistribution of lipid raft components
-
Muller G., Jung C., Wied S., Welte S., and Frick W. Insulin-mimetic signaling by the sulfonylurea glimepiride and phosphoinositolglycans involves distinct mechanisms for redistribution of lipid raft components. Biochemistry 40 (2001) 14603-14620
-
(2001)
Biochemistry
, vol.40
, pp. 14603-14620
-
-
Muller, G.1
Jung, C.2
Wied, S.3
Welte, S.4
Frick, W.5
-
10
-
-
23944498083
-
Glimepiride activates eNOS with a mechanism Akt but not caveolin-1 dependent
-
Salani B., Repetto S., Cordera R., and Maggi D. Glimepiride activates eNOS with a mechanism Akt but not caveolin-1 dependent. Biochem Biophys Res Commun 335 (2005) 832-835
-
(2005)
Biochem Biophys Res Commun
, vol.335
, pp. 832-835
-
-
Salani, B.1
Repetto, S.2
Cordera, R.3
Maggi, D.4
-
11
-
-
58149327282
-
Glimepiride upregulates eNOS activity and inhibits cytokine-induced NF-kappaB activation through a phosphoinoside 3-kinase-Akt-dependent pathway
-
Jojima T., Suzuki K., Hirama N., Uchida K., and Hattori Y. Glimepiride upregulates eNOS activity and inhibits cytokine-induced NF-kappaB activation through a phosphoinoside 3-kinase-Akt-dependent pathway. Diabetes Obes Metab 11 (2009) 143-149
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 143-149
-
-
Jojima, T.1
Suzuki, K.2
Hirama, N.3
Uchida, K.4
Hattori, Y.5
-
12
-
-
0031903015
-
Downstream signalling events regulated by phosphatidylinositol 3-kinase activity
-
Duronio V., Scheid M.P., and Ettinger S. Downstream signalling events regulated by phosphatidylinositol 3-kinase activity. Cell Signal 10 (1998) 233-239
-
(1998)
Cell Signal
, vol.10
, pp. 233-239
-
-
Duronio, V.1
Scheid, M.P.2
Ettinger, S.3
-
13
-
-
0032143284
-
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
-
Shepherd P.R., Withers D.J., and Siddle K. Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem J 333 Pt 3 (1998) 471-490
-
(1998)
Biochem J
, vol.333
, Issue.PART 3
, pp. 471-490
-
-
Shepherd, P.R.1
Withers, D.J.2
Siddle, K.3
-
14
-
-
0033844188
-
Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha
-
Martelli A.M., Borgatti P., Bortul R., et al. Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha. J Bone Miner Res 15 (2000) 1716-1730
-
(2000)
J Bone Miner Res
, vol.15
, pp. 1716-1730
-
-
Martelli, A.M.1
Borgatti, P.2
Bortul, R.3
-
15
-
-
0034836846
-
Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways
-
Carpio L., Gladu J., Goltzman D., and Rabbani S.A. Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways. Am J Physiol Endocrinol Metab 281 (2001) E489-499
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Carpio, L.1
Gladu, J.2
Goltzman, D.3
Rabbani, S.A.4
-
16
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Vlahos C.J., Matter W.F., Hui K.Y., and Brown R.F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269 (1994) 5241-5248
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
17
-
-
16644366585
-
Follistatin restricts bone morphogenetic protein (BMP)-2 action on the differentiation of osteoblasts in fetal rat mandibular cells
-
Abe Y., Abe T., Aida Y., Hara Y., and Maeda K. Follistatin restricts bone morphogenetic protein (BMP)-2 action on the differentiation of osteoblasts in fetal rat mandibular cells. J Bone Miner Res 19 (2004) 1302-1307
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1302-1307
-
-
Abe, Y.1
Abe, T.2
Aida, Y.3
Hara, Y.4
Maeda, K.5
-
18
-
-
0033452449
-
Development of mineralized nodules in fetal rat mandibular osteogenic precursor cells: requirement for dexamethasone but not for beta-glycerophosphate
-
Abe Y., Aida Y., Abe T., et al. Development of mineralized nodules in fetal rat mandibular osteogenic precursor cells: requirement for dexamethasone but not for beta-glycerophosphate. Calcif Tissue Int 66 (2000) 66-69
-
(2000)
Calcif Tissue Int
, vol.66
, pp. 66-69
-
-
Abe, Y.1
Aida, Y.2
Abe, T.3
-
19
-
-
0027251617
-
Differentiation and mineralization in osteogenic precursor cells derived from fetal rat mandibular bone
-
Abe Y., Akamine A., Aida Y., and Maeda K. Differentiation and mineralization in osteogenic precursor cells derived from fetal rat mandibular bone. Calcif Tissue Int 52 (1993) 365-371
-
(1993)
Calcif Tissue Int
, vol.52
, pp. 365-371
-
-
Abe, Y.1
Akamine, A.2
Aida, Y.3
Maeda, K.4
-
20
-
-
0036645662
-
Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts
-
Brenneisen P., Wlaschek M., Schwamborn E., et al. Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts. Biochem J 365 (2002) 31-40
-
(2002)
Biochem J
, vol.365
, pp. 31-40
-
-
Brenneisen, P.1
Wlaschek, M.2
Schwamborn, E.3
-
21
-
-
42549158610
-
The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation
-
Ulici V., Hoenselaar K.D., Gillespie J.R., and Beier F. The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation. BMC Dev Biol 8 (2008) 40
-
(2008)
BMC Dev Biol
, vol.8
, pp. 40
-
-
Ulici, V.1
Hoenselaar, K.D.2
Gillespie, J.R.3
Beier, F.4
-
22
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies S.P., Reddy H., Caivano M., and Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351 (2000) 95-105
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
23
-
-
0031955215
-
Glimepiride. A review of its use in the management of type 2 diabetes mellitus
-
Langtry H.D., and Balfour J.A. Glimepiride. A review of its use in the management of type 2 diabetes mellitus. Drugs 55 (1998) 563-584
-
(1998)
Drugs
, vol.55
, pp. 563-584
-
-
Langtry, H.D.1
Balfour, J.A.2
-
24
-
-
0031023661
-
Inhibition of MG-63 cell proliferation and PDGF-stimulated cellular processes by inhibitors of phosphatidylinositol 3-kinase
-
Thomas J.E., Venugopalan M., Galvin R., et al. Inhibition of MG-63 cell proliferation and PDGF-stimulated cellular processes by inhibitors of phosphatidylinositol 3-kinase. J Cell Biochem 64 (1997) 182-195
-
(1997)
J Cell Biochem
, vol.64
, pp. 182-195
-
-
Thomas, J.E.1
Venugopalan, M.2
Galvin, R.3
-
25
-
-
23044506069
-
Bone morphogenetic protein regulation of early osteoblast genes in human marrow stromal cells is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase signaling
-
Osyczka A.M., and Leboy P.S. Bone morphogenetic protein regulation of early osteoblast genes in human marrow stromal cells is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase signaling. Endocrinology 146 (2005) 3428-3437
-
(2005)
Endocrinology
, vol.146
, pp. 3428-3437
-
-
Osyczka, A.M.1
Leboy, P.S.2
-
26
-
-
58649098207
-
Ultrasound increased BMP-2 expression via PI3K, Akt, c-Fos/c-Jun, and AP-1 pathways in cultured osteoblasts
-
Hou C.H., Hou S.M., and Tang C.H. Ultrasound increased BMP-2 expression via PI3K, Akt, c-Fos/c-Jun, and AP-1 pathways in cultured osteoblasts. J Cell Biochem 106 (2009) 7-15
-
(2009)
J Cell Biochem
, vol.106
, pp. 7-15
-
-
Hou, C.H.1
Hou, S.M.2
Tang, C.H.3
-
27
-
-
34250348437
-
Stimulatory effect of puerarin on bone formation through activation of PI3K/Akt pathway in rat calvaria osteoblasts
-
Zhang Y., Zeng X., Zhang L., and Zheng X. Stimulatory effect of puerarin on bone formation through activation of PI3K/Akt pathway in rat calvaria osteoblasts. Planta Med 73 (2007) 341-347
-
(2007)
Planta Med
, vol.73
, pp. 341-347
-
-
Zhang, Y.1
Zeng, X.2
Zhang, L.3
Zheng, X.4
-
28
-
-
40949128686
-
Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways
-
Raucci A., Bellosta P., Grassi R., Basilico C., and Mansukhani A. Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways. J Cell Physiol 215 (2008) 442-451
-
(2008)
J Cell Physiol
, vol.215
, pp. 442-451
-
-
Raucci, A.1
Bellosta, P.2
Grassi, R.3
Basilico, C.4
Mansukhani, A.5
-
29
-
-
0027939430
-
Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002
-
Sanchez-Margalet V., Goldfine I.D., Vlahos C.J., and Sung C.K. Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002. Biochem Biophys Res Commun 204 (1994) 446-452
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 446-452
-
-
Sanchez-Margalet, V.1
Goldfine, I.D.2
Vlahos, C.J.3
Sung, C.K.4
-
30
-
-
34247567909
-
Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway
-
Dey A., and Cederbaum A.I. Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway. Arch Biochem Biophys 461 (2007) 275-286
-
(2007)
Arch Biochem Biophys
, vol.461
, pp. 275-286
-
-
Dey, A.1
Cederbaum, A.I.2
-
31
-
-
28544442352
-
Enhancement of mouse sperm motility by the PI3-kinase inhibitor LY294002 does not result in toxic effects on preimplantation embryo development
-
Luconi M., Torcia S., Grillo D., et al. Enhancement of mouse sperm motility by the PI3-kinase inhibitor LY294002 does not result in toxic effects on preimplantation embryo development. Hum Reprod 20 (2005) 3500-3504
-
(2005)
Hum Reprod
, vol.20
, pp. 3500-3504
-
-
Luconi, M.1
Torcia, S.2
Grillo, D.3
-
32
-
-
0041672472
-
Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells
-
Shingu T., Yamada K., Hara N., et al. Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells. Cancer Res 63 (2003) 4044-4047
-
(2003)
Cancer Res
, vol.63
, pp. 4044-4047
-
-
Shingu, T.1
Yamada, K.2
Hara, N.3
-
33
-
-
0032127953
-
Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium
-
Jun S.S., Chen Z., Pace M.C., and Shaul P.W. Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium. J Clin Invest 102 (1998) 176-183
-
(1998)
J Clin Invest
, vol.102
, pp. 176-183
-
-
Jun, S.S.1
Chen, Z.2
Pace, M.C.3
Shaul, P.W.4
-
34
-
-
0031732762
-
Estrogen upregulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells
-
Armour K.E., and Ralston S.H. Estrogen upregulates endothelial constitutive nitric oxide synthase expression in human osteoblast-like cells. Endocrinology 139 (1998) 799-802
-
(1998)
Endocrinology
, vol.139
, pp. 799-802
-
-
Armour, K.E.1
Ralston, S.H.2
-
35
-
-
0024312556
-
Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones
-
Ernst M., Heath J.K., and Rodan G.A. Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones. Endocrinology 125 (1989) 825-833
-
(1989)
Endocrinology
, vol.125
, pp. 825-833
-
-
Ernst, M.1
Heath, J.K.2
Rodan, G.A.3
-
36
-
-
0025838316
-
Modulation of transforming growth factor-beta production in normal human osteoblast-like cells by 17 beta-estradiol and parathyroid hormone
-
Oursler M.J., Cortese C., Keeting P., et al. Modulation of transforming growth factor-beta production in normal human osteoblast-like cells by 17 beta-estradiol and parathyroid hormone. Endocrinology 129 (1991) 3313-3320
-
(1991)
Endocrinology
, vol.129
, pp. 3313-3320
-
-
Oursler, M.J.1
Cortese, C.2
Keeting, P.3
-
37
-
-
0034727094
-
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
-
Simoncini T., Hafezi-Moghadam A., Brazil D.P., et al. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 407 (2000) 538-541
-
(2000)
Nature
, vol.407
, pp. 538-541
-
-
Simoncini, T.1
Hafezi-Moghadam, A.2
Brazil, D.P.3
-
38
-
-
0034736065
-
Insulin stimulates production of nitric oxide via ERK in osteoblast cells
-
Kim S.J., Chun J.Y., and Kim M.S. Insulin stimulates production of nitric oxide via ERK in osteoblast cells. Biochem Biophys Res Commun 278 (2000) 712-718
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 712-718
-
-
Kim, S.J.1
Chun, J.Y.2
Kim, M.S.3
-
39
-
-
33947150636
-
Insulin-like effects of visfatin on human osteoblasts
-
Xie H., Tang S.Y., Luo X.H., et al. Insulin-like effects of visfatin on human osteoblasts. Calcif Tissue Int 80 (2007) 201-210
-
(2007)
Calcif Tissue Int
, vol.80
, pp. 201-210
-
-
Xie, H.1
Tang, S.Y.2
Luo, X.H.3
-
40
-
-
0032898954
-
Hydroxyapatite coated with insulin-like growth factor 1 (IGF1) stimulates human osteoblast activity in vitro
-
Zambonin G., Grano M., Greco G., Oreffo R.O., and Triffit J.T. Hydroxyapatite coated with insulin-like growth factor 1 (IGF1) stimulates human osteoblast activity in vitro. Acta Orthop Scand 70 (1999) 217-220
-
(1999)
Acta Orthop Scand
, vol.70
, pp. 217-220
-
-
Zambonin, G.1
Grano, M.2
Greco, G.3
Oreffo, R.O.4
Triffit, J.T.5
-
41
-
-
0021229954
-
Insulin-like growth factor I supports differentiation of cultured osteoblast-like cells
-
Schmid C., Steiner T., and Froesch E.R. Insulin-like growth factor I supports differentiation of cultured osteoblast-like cells. FEBS Lett 173 (1984) 48-52
-
(1984)
FEBS Lett
, vol.173
, pp. 48-52
-
-
Schmid, C.1
Steiner, T.2
Froesch, E.R.3
-
42
-
-
0025763692
-
Simulated weightlessness and bone metabolism: impairment of insulin effect on alkaline phosphatase activity in bone tissue
-
Yamaguchi M., Ozaki K., and Hoshi T. Simulated weightlessness and bone metabolism: impairment of insulin effect on alkaline phosphatase activity in bone tissue. Res Exp Med (Berl) 191 (1991) 113-119
-
(1991)
Res Exp Med (Berl)
, vol.191
, pp. 113-119
-
-
Yamaguchi, M.1
Ozaki, K.2
Hoshi, T.3
|