-
1
-
-
12944322216
-
Anthrax toxin: The long and winding road that leads to the kill
-
Abrami, L., N. Reig, and F. G. Goot. 2005. Anthrax toxin: the long and winding road that leads to the kill. Trends Microbiol. 13:72-78.
-
(2005)
Trends Microbiol.
, vol.13
, pp. 72-78
-
-
Abrami, L.1
Reig, N.2
Goot, F.G.3
-
2
-
-
0030859761
-
Site directed mutagenesis of histidine residues in anthrax toxin lethal factor binding domain reduces toxicity
-
Arora, N. 1997. Site directed mutagenesis of histidine residues in anthrax toxin lethal factor binding domain reduces toxicity. Mol. Cell. Biochem. 177:7-14.
-
(1997)
Mol. Cell. Biochem.
, vol.177
, pp. 7-14
-
-
Arora, N.1
-
3
-
-
0027403919
-
Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides
-
Arora, N., and S. H. Leppla. 1993. Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides. J. Biol. Chem. 268:3334-3341.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 3334-3341
-
-
Arora, N.1
Leppla, S.H.2
-
4
-
-
40849102523
-
Efficient production and characterization of Bacillus anthracis lethal factor and a novel inactive mutant rLFm-Y236F
-
Cao, S., Z. Liu, A. Guo, Y. Li, C. Zhang, G. Wu, C. Feng, Y. Tan, and H. Chen. 2008. Efficient production and characterization of Bacillus anthracis lethal factor and a novel inactive mutant rLFm-Y236F. Protein Expr. Purif. 59:25-30.
-
(2008)
Protein Expr. Purif.
, vol.59
, pp. 25-30
-
-
Cao, S.1
Liu, Z.2
Guo, A.3
Li, Y.4
Zhang, C.5
Wu, G.6
Feng, C.7
Tan, Y.8
Chen, H.9
-
5
-
-
70349413068
-
Investigation of new dominant-negative inhibitors of anthrax protective antigen mutants for use in therapy and vaccination
-
Cao, S., A. Guo, Z. Liu, Y. Tan, G. Wu, C. Zhang, Y. Zhao, and H. Chen. 2009. Investigation of new dominant-negative inhibitors of anthrax protective antigen mutants for use in therapy and vaccination. Infect. Immun. 77:4679-4687.
-
(2009)
Infect. Immun.
, vol.77
, pp. 4679-4687
-
-
Cao, S.1
Guo, A.2
Liu, Z.3
Tan, Y.4
Wu, G.5
Zhang, C.6
Zhao, Y.7
Chen, H.8
-
6
-
-
0036468526
-
Quickening the pace of anthrax research: Three advances point towards possible therapies
-
Chaudry, G., J. Moayeri, M. Liu, and S. H. Leppla. 2002. Quickening the pace of anthrax research: three advances point towards possible therapies. Trends Microbiol. 10:58-62.
-
(2002)
Trends Microbiol.
, vol.10
, pp. 58-62
-
-
Chaudry, G.1
Moayeri, J.2
Liu, M.3
Leppla, S.H.4
-
7
-
-
33748350938
-
Identification of three crucial histidine residues (His115, His132 and His297) in porcine deoxyribonuclease II
-
Cheng, Y., C. Hsueh, S. Lu, and T. Liao. 2006. Identification of three crucial histidine residues (His115, His132 and His297) in porcine deoxyribonuclease II. Biochem. J. 398:177-185.
-
(2006)
Biochem. J.
, vol.398
, pp. 177-185
-
-
Cheng, Y.1
Hsueh, C.2
Lu, S.3
Liao, T.4
-
8
-
-
0038322024
-
Anthrax lethal factor proteolysis and inactivation of MAPK kinase
-
Chopra, A. P., S. A. Boone, X. Liang, and N. S. Duesbery. 2003. Anthrax lethal factor proteolysis and inactivation of MAPK kinase. J. Biol. Chem. 278:9402-9406.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9402-9406
-
-
Chopra, A.P.1
Boone, S.A.2
Liang, X.3
Duesbery, N.S.4
-
9
-
-
7944233858
-
His-404 and His-405 are essential for enzyme catalytic activities of a bacterial indole-3-acetyl-L-aspartic acid hydrolase
-
Chou, J. C., W. H. Welch, and J. D. Cohen. 2004. His-404 and His-405 are essential for enzyme catalytic activities of a bacterial indole-3-acetyl-L- aspartic acid hydrolase. Plant Cell Physiol. 45:1335-1341.
-
(2004)
Plant Cell Physiol.
, vol.45
, pp. 1335-1341
-
-
Chou, J.C.1
Welch, W.H.2
Cohen, J.D.3
-
10
-
-
0033539028
-
Anthrax
-
Dixon, T. C., M. Meselson, J. Guillemin, and P. C. Hanna. 1999. Anthrax. N. Engl. J. Med. 341:815-826.
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 815-826
-
-
Dixon, T.C.1
Meselson, M.2
Guillemin, J.3
Hanna, P.C.4
-
11
-
-
18244414803
-
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor
-
Duesbery, N. S., C. P. Webb, S. H. Leppla, V. M. Gordon, K. R. Klimpel, T. D. Copeland, N. G. Ahn, M. K. Oskarsson, K. Fukasawa, K. D. Paull, and G. V. Woude. 1998. Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science 280:734-737.
-
(1998)
Science
, vol.280
, pp. 734-737
-
-
Duesbery, N.S.1
Webb, C.P.2
Leppla, S.H.3
Gordon, V.M.4
Klimpel, K.R.5
Copeland, T.D.6
Ahn, N.G.7
Oskarsson, M.K.8
Fukasawa, K.9
Paull, K.D.10
Woude, G.V.11
-
12
-
-
11844262754
-
Mutation analysis of the histidine residues in the glycylglycine endopeptidase ALE-1
-
DOI 10.1128/JB.187.2.480-487.2005
-
Fujiwara, T., S. Aoki, H. Komatsuzawa, T. Nishida, M. Ohara, H. Suginaka, and M. Sugai. 2005. Mutation analysis of the histidine residues in the glycylglycine endopeptidase ALE-1. J. Bacteriol. 187:480-487. (Pubitemid 40096236)
-
(2005)
Journal of Bacteriology
, vol.187
, Issue.2
, pp. 480-487
-
-
Fujiwara, T.1
Aoki, S.2
Komatsuzawa, H.3
Nishida, T.4
Ohara, M.5
Suginaka, H.6
Sugai, M.7
-
13
-
-
0031946979
-
Lethal factor active-site mutations affect catalytic activity in vitro
-
Hammond, S. E., and P. C. Hanna. 1998. Lethal factor active-site mutations affect catalytic activity in vitro. Infect. Immun. 66:2374-2378.
-
(1998)
Infect. Immun.
, vol.66
, pp. 2374-2378
-
-
Hammond, S.E.1
Hanna, P.C.2
-
14
-
-
0035098034
-
Effect of His1992 mutation on the activity of alginate lyase A1-III from sphingomonas species A1
-
Hye-jin, Y., Y. J. Choi, O. Miyake, W. Hashimoto, K. Mutata, and B. Mikami. 2001. Effect of His1992 mutation on the activity of alginate lyase A1-III from sphingomonas species A1. J. Microbiol. Biotechnol. 11:118-123.
-
(2001)
J. Microbiol. Biotechnol.
, vol.11
, pp. 118-123
-
-
Hye-jin, Y.1
Choi, Y.J.2
Miyake, O.3
Hashimoto, W.4
Mutata, K.5
Mikami, B.6
-
15
-
-
0348111399
-
Implication of pH in the catalytic properties of anthrax lethal factor
-
Kim, J., Y. G. Chai, and M. Y. Yoon. 2004. Implication of pH in the catalytic properties of anthrax lethal factor. Biochem. Biophys. Res. Commun. 313:217-222.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.313
, pp. 217-222
-
-
Kim, J.1
Chai, Y.G.2
Yoon, M.Y.3
-
16
-
-
77953718004
-
Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization
-
Kintzer, A. F., H. J. Sterling, L. I. Tang, A. Abdul-Gader, A. J. Miles, B. A. Wallance, E. R. Williams, and B. A. Krantz. 2010. Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization. J. Mol. Biol. 399:741-758.
-
(2010)
J. Mol. Biol.
, vol.399
, pp. 741-758
-
-
Kintzer, A.F.1
Sterling, H.J.2
Tang, L.I.3
Abdul-Gader, A.4
Miles, A.J.5
Wallance, B.A.6
Williams, E.R.7
Krantz, B.A.8
-
17
-
-
69349098830
-
The protective antigen component of anthrax toxin forms functional octameric complexes
-
Kintzer, A. F., K. L. Thoren, H. J. Sterling, K. C. Dong, G. K. Feld, I. I. Tang, E. R. Williams, J. M. Berger, and B. A. Krantz. 2009. The protective antigen component of anthrax toxin forms functional octameric complexes. J. Mol. Biol. 392:614-629.
-
(2009)
J. Mol. Biol.
, vol.392
, pp. 614-629
-
-
Kintzer, A.F.1
Thoren, K.L.2
Sterling, H.J.3
Dong, K.C.4
Feld, G.K.5
Tang, I.I.6
Williams, E.R.7
Berger, J.M.8
Krantz, B.A.9
-
18
-
-
0028088404
-
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
-
Klimpel, K. R., N. Arora, and S. H. Leppla. 1994. Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity. Mol. Microbiol. 13:1093-1100.
-
(1994)
Mol. Microbiol.
, vol.13
, pp. 1093-1100
-
-
Klimpel, K.R.1
Arora, N.2
Leppla, S.H.3
-
19
-
-
0028046607
-
Zinc content of the Bacillus anthracis lethal factor
-
Kochi, S. K., G. Schiavo, M. Mock, and C. Montecucco. 1994. Zinc content of the Bacillus anthracis lethal factor. FEMS Microbiol. Lett. 124:343-348.
-
(1994)
FEMS Microbiol. Lett.
, vol.124
, pp. 343-348
-
-
Kochi, S.K.1
Schiavo, G.2
Mock, M.3
Montecucco, C.4
-
20
-
-
0034833135
-
Purification of anthrax edema factor from Escherichia coli and identification of residues required for binding to anthrax protective antigen
-
Kumar, P., N. Ahuja, and R. Bhatnagar. 2001. Purification of anthrax edema factor from Escherichia coli and identification of residues required for binding to anthrax protective antigen. Infect. Immun. 69:6532-6536.
-
(2001)
Infect. Immun.
, vol.69
, pp. 6532-6536
-
-
Kumar, P.1
Ahuja, N.2
Bhatnagar, R.3
-
21
-
-
4444267311
-
Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
-
Lacy, D. B., D. J. Wigelsworth, R. A. Melnyk, S. C. Harrison, and R. J. Collier. 2004. Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. Proc. Natl. Acad. Sci. U. S. A. 101:13147-13151.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 13147-13151
-
-
Lacy, D.B.1
Wigelsworth, D.J.2
Melnyk, R.A.3
Harrison, S.C.4
Collier, R.J.5
-
22
-
-
0037169549
-
Mapping the anthrax protective antigen binding site on the lethal and edema factors
-
Lacy, D. B., M. Mourez, A. Fouassier, and R. J. Collier. 2002. Mapping the anthrax protective antigen binding site on the lethal and edema factors. J. Biol. Chem. 277:3006-3010.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3006-3010
-
-
Lacy, D.B.1
Mourez, M.2
Fouassier, A.3
Collier, R.J.4
-
23
-
-
0001616921
-
Anthrax toxin fusion proteins for intracellular delivery of macromolecules
-
Leppla, S. H., N. Arora, and M. Varughese. 1999. Anthrax toxin fusion proteins for intracellular delivery of macromolecules. J. Appl. Microbiol. 87:284.
-
(1999)
J. Appl. Microbiol.
, vol.87
, pp. 284
-
-
Leppla, S.H.1
Arora, N.2
Varughese, M.3
-
25
-
-
0035097284
-
Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin
-
Mogridge, J., M. Mourez, and R. J. Collier. 2001. Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin. J. Bacteriol. 183:2111-2116.
-
(2001)
J. Bacteriol.
, vol.183
, pp. 2111-2116
-
-
Mogridge, J.1
Mourez, M.2
Collier, R.J.3
-
26
-
-
3242804491
-
Stop the killer: How to inhibit the anthrax lethal factor metalloprotease
-
Montecucco, C., F. Tonello, and G. Zanotti. 2004. Stop the killer: how to inhibit the anthrax lethal factor metalloprotease. Trends Biochem. Sci. 29:282-285.
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 282-285
-
-
Montecucco, C.1
Tonello, F.2
Zanotti, G.3
-
27
-
-
0036603521
-
2001: A year of major advances in anthrax toxin research
-
Mourez, M., D. B. Lacy, K. Cunningham, R. Legmann, B. R. Sellman, J. Mogridge, and R. J. Collier. 2002. 2001: a year of major advances in anthrax toxin research. Trends Microbiol. 10:287-293.
-
(2002)
Trends Microbiol.
, vol.10
, pp. 287-293
-
-
Mourez, M.1
Lacy, D.B.2
Cunningham, K.3
Legmann, R.4
Sellman, B.R.5
Mogridge, J.6
Collier, R.J.7
-
28
-
-
0035829518
-
Crystal structure of the anthrax lethal factor
-
Pannifer, A. D., T. Y. Wong, R. Schwarzenbacher, M. Renatus, C. Petosa, J. Bienkowska, D. B. Lacy, R. J. Collier, S. Park, S. H. Leppla, P. Hanna, and R. C. Liddington. 2001. Crystal structure of the anthrax lethal factor. Nature 414:229-233.
-
(2001)
Nature
, vol.414
, pp. 229-233
-
-
Pannifer, A.D.1
Wong, T.Y.2
Schwarzenbacher, R.3
Renatus, M.4
Petosa, C.5
Bienkowska, J.6
Lacy, D.B.7
Collier, R.J.8
Park, S.9
Leppla, S.H.10
Hanna, P.11
Liddington, R.C.12
-
29
-
-
0037144590
-
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition
-
Park, J. M., F. R. Greten, Z. W. Li, and M. Karin. 2002. Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition. Science 297:2048-2051.
-
(2002)
Science
, vol.297
, pp. 2048-2051
-
-
Park, J.M.1
Greten, F.R.2
Li, Z.W.3
Karin, M.4
-
30
-
-
0036295213
-
Lethal toxin of Bacillus anthracis causes apoptosis of macrophages
-
Popov, S. G., R. Villasmil, J. Bernardi, E. Grene, J. Cardwell, A. Wu, D. Alibek, C. Bailey, and K. Alibek. 2002. Lethal toxin of Bacillus anthracis causes apoptosis of macrophages. Biochem. Biophys. Res. Commun. 283:349-355.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.283
, pp. 349-355
-
-
Popov, S.G.1
Villasmil, R.2
Bernardi, J.3
Grene, E.4
Cardwell, J.5
Wu, A.6
Alibek, D.7
Bailey, C.8
Alibek, K.9
-
31
-
-
1642385648
-
Anthrax toxin: Can a little be a good thing?
-
Sanchez, A. M., and K. A. Bradley. 2004. Anthrax toxin: can a little be a good thing? Trends Microbiol. 12:143-145.
-
(2004)
Trends Microbiol.
, vol.12
, pp. 143-145
-
-
Sanchez, A.M.1
Bradley, K.A.2
-
32
-
-
0346433832
-
Tyrosine-728 and glutamic acid-735 are essential for the metalloproteolytic activity of the lethal factor of Bacillus anthracis
-
Tonello, F., L. Naletto, V. Romanello, F. D. Molin, and C. Montecucco. 2004. Tyrosine-728 and glutamic acid-735 are essential for the metalloproteolytic activity of the lethal factor of Bacillus anthracis. Biochem. Biophys. Res. Commun. 313:496-502.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.313
, pp. 496-502
-
-
Tonello, F.1
Naletto, L.2
Romanello, V.3
Molin, F.D.4
Montecucco, C.5
-
33
-
-
0037173617
-
Screening inhibitors of anthrax lethal factor
-
DOI 10.1038/418386a
-
Tonello, F., M. Seveso, O. Marin, M. Mock, and C. Montecucco. 2002. Screening inhibitors of anthrax lethal factor. Nature 418:386. (Pubitemid 34826833)
-
(2002)
Nature
, vol.418
, Issue.6896
, pp. 386
-
-
Tonello, F.1
Seveso, M.2
Marin, O.3
Mock, M.4
Montecucco, C.5
-
34
-
-
0141994729
-
The metalloproteolytic activity of the anthrax lethal factor is substrate-inhibited
-
Tonello, F., P. Ascenzi, and C. Montecucco. 2003. The metalloproteolytic activity of the anthrax lethal factor is substrate-inhibited. J. Biol. Chem. 278:40075-40078.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40075-40078
-
-
Tonello, F.1
Ascenzi, P.2
Montecucco, C.3
-
35
-
-
0034672216
-
Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor
-
DOI 10.1042/0264-6021:3520739
-
Vitale, G., L. Bernardi, G. Napolitani, M. Mock, and C. Montecucco. 2000. Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor. Biochem. J. 3:739-745. (Pubitemid 32015030)
-
(2000)
Biochemical Journal
, vol.352
, Issue.3
, pp. 739-745
-
-
Vitale, G.1
Bernardi, L.2
Napolitani, G.3
Mock, M.4
Montecucco, C.5
-
36
-
-
0032581369
-
Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages
-
Vitale, G., R. Pellizzari, C. Recchi, G. Napolitani, M. Mock, and C. Montecucco. 1998. Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages. Biochem. Biophys. Res. Commun. 248:706-711.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.248
, pp. 706-711
-
-
Vitale, G.1
Pellizzari, R.2
Recchi, C.3
Napolitani, G.4
Mock, M.5
Montecucco, C.6
-
37
-
-
0037868151
-
Characterization of dominant-negative forms of anthrax protective antigen
-
Yan, M., and R. J. Collier. 2003. Characterization of dominant-negative forms of anthrax protective antigen. Mol. Med. 9:46-51.
-
(2003)
Mol. Med.
, vol.9
, pp. 46-51
-
-
Yan, M.1
Collier, R.J.2
-
38
-
-
38649141825
-
Selection and evaluation of the immunogenicity of protective antigen mutants as anthrax vaccine candidates
-
Yan, M., M. H. Roehrl, E. Basar, and J. Y. Wang. 2008. Selection and evaluation of the immunogenicity of protective antigen mutants as anthrax vaccine candidates. Vaccine 26:947-955.
-
(2008)
Vaccine
, vol.26
, pp. 947-955
-
-
Yan, M.1
Roehrl, M.H.2
Basar, E.3
Wang, J.Y.4
|