A 96-well plate assay for CYP4503A induction using cryopreserved human hepatocytes

Drug Metabolism and Disposition

Volumn 38, Issue 11, 2010, Pages 1912-1916

  Kamiguchi, Naomi ^a   Aoyama, Eiji ^a   Okuda, Teruaki ^a   Moriwaki, Toshiya ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AVASIMIBE; CARBAMAZEPINE; CIMETIDINE; CYTOCHROME P450 3A; EFAVIRENZ; FUROSEMIDE; MODAFINIL; NIFEDIPINE; PHENOBARBITAL; PHENYTOIN; RIFAMPICIN; RITONAVIR; SULFINPYRAZONE;

ARTICLE; BASEMENT MEMBRANE; CYTOTOXICITY; DRUG ANTAGONISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER CELL; PRIORITY JOURNAL;

BIOLOGICAL ASSAY; CARBAMAZEPINE; CELL CULTURE TECHNIQUES; CELL MEMBRANE; CELLS, CULTURED; CRYOPRESERVATION; CYTOCHROME P-450 CYP3A; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; HUMANS; PHARMACEUTICAL PREPARATIONS; PHENYTOIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIFAMPIN;

EID: 78049359694     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.028613     Document Type: Article

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