-
1
-
-
18744433250
-
Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex
-
Kohmura N, et al. (1998) Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron 20:1137-1151.
-
(1998)
Neuron
, vol.20
, pp. 1137-1151
-
-
Kohmura, N.1
-
2
-
-
0033063445
-
A striking organization of a large family of human neural cadherin-like cell adhesion genes
-
Wu Q, Maniatis T (1999) A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97:779-790.
-
(1999)
Cell
, vol.97
, pp. 779-790
-
-
Wu, Q.1
Maniatis, T.2
-
3
-
-
13944269194
-
Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons
-
Esumi S, et al. (2005) Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons. Nat Genet 37:171-176.
-
(2005)
Nat Genet
, vol.37
, pp. 171-176
-
-
Esumi, S.1
-
4
-
-
33750078697
-
Allelic gene regulation of Pcdh-alpha and Pcdh-gamma clusters involving both monoallelic and biallelic expression in single Purkinje cells
-
Kaneko R, et al. (2006) Allelic gene regulation of Pcdh-alpha and Pcdh-gamma clusters involving both monoallelic and biallelic expression in single Purkinje cells. J Biol Chem 281:30551-30560.
-
(2006)
J Biol Chem
, vol.281
, pp. 30551-30560
-
-
Kaneko, R.1
-
5
-
-
18444371112
-
Promoter choice determines splice site selection in protocadherin alpha and gamma pre-mRNA splicing
-
Tasic B, et al. (2002) Promoter choice determines splice site selection in protocadherin alpha and gamma pre-mRNA splicing. Mol Cell 10:21-33.
-
(2002)
Mol Cell
, vol.10
, pp. 21-33
-
-
Tasic, B.1
-
6
-
-
0036682529
-
Molecular mechanisms governing Pcdh-gamma gene expression: Evidence for a multiple promoter and cis-alternative splicing model
-
Wang X, Su H, Bradley A (2002) Molecular mechanisms governing Pcdh-gamma gene expression: Evidence for a multiple promoter and cis-alternative splicing model. Genes Dev 16:1890-1905.
-
(2002)
Genes Dev
, vol.16
, pp. 1890-1905
-
-
Wang, X.1
Su, H.2
Bradley, A.3
-
7
-
-
0029616019
-
Protocadherin Pcdh2 shows properties similar to, but distinct from, those of classical cadherins
-
Obata S, et al. (1995) Protocadherin Pcdh2 shows properties similar to, but distinct from, those of classical cadherins. J Cell Sci 108:3765-3773.
-
(1995)
J Cell Sci
, vol.108
, pp. 3765-3773
-
-
Obata, S.1
-
8
-
-
33746826046
-
Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesion
-
Reiss K, et al. (2006) Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesion. J Biol Chem 281:21735-21744.
-
(2006)
J Biol Chem
, vol.281
, pp. 21735-21744
-
-
Reiss, K.1
-
9
-
-
10344257249
-
Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha
-
Murata Y, Hamada S, Morishita H, Mutoh T, Yagi T (2004) Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha. J Biol Chem 279:49508-49516.
-
(2004)
J Biol Chem
, vol.279
, pp. 49508-49516
-
-
Murata, Y.1
Hamada, S.2
Morishita, H.3
Mutoh, T.4
Yagi, T.5
-
10
-
-
33845949211
-
Structure of the cadherin-related neuronal receptor/protocadherin-alpha first extracellular cadherin domain reveals diversity across cadherin families
-
Morishita H, et al. (2006) Structure of the cadherin-related neuronal receptor/protocadherin-alpha first extracellular cadherin domain reveals diversity across cadherin families. J Biol Chem 281:33650-33663.
-
(2006)
J Biol Chem
, vol.281
, pp. 33650-33663
-
-
Morishita, H.1
-
11
-
-
60149108896
-
Gamma-protocadherins regulate neuronal survival but are dispensable for circuit formation in retina
-
Lefebvre JL, Zhang Y, Meister M, Wang X, Sanes JR (2008) Gamma-protocadherins regulate neuronal survival but are dispensable for circuit formation in retina. Development 135:4141-4151.
-
(2008)
Development
, vol.135
, pp. 4141-4151
-
-
Lefebvre, J.L.1
Zhang, Y.2
Meister, M.3
Wang, X.4
Sanes, J.R.5
-
12
-
-
18744410937
-
Gamma protocadherins are required for survival of spinal interneurons
-
DOI 10.1016/S0896-6273(02)01090-5
-
Wang X, et al. (2002) Gamma protocadherins are required for survival of spinal interneurons. Neuron 36:843-854. (Pubitemid 35447856)
-
(2002)
Neuron
, vol.36
, Issue.5
, pp. 843-854
-
-
Wang, X.1
Weiner, J.A.2
Levi, S.3
Craig, A.M.4
Bradley, A.5
Sanes, J.R.6
-
13
-
-
11844301330
-
Gamma protocadherins are required for synaptic development in the spinal cord
-
Weiner JA, Wang X, Tapia JC, Sanes JR (2005) Gamma protocadherins are required for synaptic development in the spinal cord. Proc Natl Acad Sci USA 102:8-14.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8-14
-
-
Weiner, J.A.1
Wang, X.2
Tapia, J.C.3
Sanes, J.R.4
-
14
-
-
60149105704
-
A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: Insights from genetic analyses of the protocadherin-gamma gene cluster
-
Prasad T, Wang X, Gray PA, Weiner JA (2008) A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: Insights from genetic analyses of the protocadherin-gamma gene cluster. Development 135:4153-4164.
-
(2008)
Development
, vol.135
, pp. 4153-4164
-
-
Prasad, T.1
Wang, X.2
Gray, P.A.3
Weiner, J.A.4
-
15
-
-
43049124717
-
The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse
-
Hasegawa S, et al. (2008) The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse. Mol Cell Neurosci 38:66-79.
-
(2008)
Mol Cell Neurosci
, vol.38
, pp. 66-79
-
-
Hasegawa, S.1
-
16
-
-
67651176011
-
Protocadherin-alpha family is required for serotonergic projections to appropriately innervate target brain areas
-
Katori S, et al. (2009) Protocadherin-alpha family is required for serotonergic projections to appropriately innervate target brain areas. J Neurosci 29:9137-9147.
-
(2009)
J Neurosci
, vol.29
, pp. 9137-9147
-
-
Katori, S.1
-
17
-
-
59149086069
-
Alpha- and gamma-protocadherins negatively regulate PYK2
-
Chen J, et al. (2008) Alpha- and gamma-protocadherins negatively regulate PYK2. J Biol Chem 284:2880-2890.
-
(2008)
J Biol Chem
, vol.284
, pp. 2880-2890
-
-
Chen, J.1
-
18
-
-
77956380405
-
Phosphorylation of protocadherin proteins by the receptor tyrosine kinase Ret
-
Schalm SS, Ballif BA, Buchanan SM, Phillips GR, Maniatis TM (2010) Phosphorylation of protocadherin proteins by the receptor tyrosine kinase Ret. Proc Natl Acad Sci USA 107:13894-13899.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13894-13899
-
-
Schalm, S.S.1
Ballif, B.A.2
Buchanan, S.M.3
Phillips, G.R.4
Maniatis, T.M.5
-
19
-
-
34347325154
-
Combinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processing
-
Bonn S, Seeburg PH, Schwarz MK (2007) Combinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processing. Mol Cell Biol 27:4121-4132.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4121-4132
-
-
Bonn, S.1
Seeburg, P.H.2
Schwarz, M.K.3
-
20
-
-
15744388308
-
Presenilin-dependent processing and nuclear function of gamma-protocadherins
-
Haas IG, Frank M, Véron N, Kemler R (2005) Presenilin-dependent processing and nuclear function of gamma-protocadherins. J Biol Chem 280:9313-9319.
-
(2005)
J Biol Chem
, vol.280
, pp. 9313-9319
-
-
Haas, I.G.1
Frank, M.2
Véron, N.3
Kemler, R.4
-
21
-
-
18144427413
-
Gamma-protocadherins, presenilin-mediated release of C-terminal fragment promotes locus expression
-
Hambsch B, Grinevich V, Seeburg PH, Schwarz MK (2005) Gamma-protocadherins, presenilin-mediated release of C-terminal fragment promotes locus expression. J Biol Chem 280:15888-15897.
-
(2005)
J Biol Chem
, vol.280
, pp. 15888-15897
-
-
Hambsch, B.1
Grinevich, V.2
Seeburg, P.H.3
Schwarz, M.K.4
-
22
-
-
0036727125
-
Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling
-
Fortini ME (2002) Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling. Nat Rev Mol Cell Biol 3:673-684.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 673-684
-
-
Fortini, M.E.1
-
23
-
-
0141429160
-
A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations
-
Marambaud P, et al. (2003) A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations. Cell 114:635-645.
-
(2003)
Cell
, vol.114
, pp. 635-645
-
-
Marambaud, P.1
-
24
-
-
0033639117
-
Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins
-
Struhl G, Adachi A (2000) Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. Mol Cell 6:625-636.
-
(2000)
Mol Cell
, vol.6
, pp. 625-636
-
-
Struhl, G.1
Adachi, A.2
-
25
-
-
0031036380
-
Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation
-
Qi Y, Wang JK, McMillian M, Chikaraishi DM (1997) Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation. J Neurosci 17:1217-1225.
-
(1997)
J Neurosci
, vol.17
, pp. 1217-1225
-
-
Qi, Y.1
Wang, J.K.2
McMillian, M.3
Chikaraishi, D.M.4
-
26
-
-
34547212309
-
The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing
-
DOI 10.1016/j.molcel.2007.07.015, PII S1097276507004881
-
Makeyev EV, Zhang J, Carrasco MA, Maniatis T (2007) The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 27:435-448. (Pubitemid 47126944)
-
(2007)
Molecular Cell
, vol.27
, Issue.3
, pp. 435-448
-
-
Makeyev, E.V.1
Zhang, J.2
Carrasco, M.A.3
Maniatis, T.4
-
27
-
-
0038790311
-
Gamma-protocadherins are targeted to subsets of synapses and intracellular organelles in neurons
-
Phillips GR, et al. (2003) Gamma-protocadherins are targeted to subsets of synapses and intracellular organelles in neurons. J Neurosci 23:5096-5104.
-
(2003)
J Neurosci
, vol.23
, pp. 5096-5104
-
-
Phillips, G.R.1
-
28
-
-
49049096465
-
Inhibition of protocadherin-alpha function results in neuronal death in the developing zebrafish
-
Emond MR, Jontes JD (2008) Inhibition of protocadherin-alpha function results in neuronal death in the developing zebrafish. Dev Biol 321:175-187.
-
(2008)
Dev Biol
, vol.321
, pp. 175-187
-
-
Emond, M.R.1
Jontes, J.D.2
-
29
-
-
60149106363
-
Gamma-protocadherin homophilic interaction and intracellular trafficking is controlled by the cytoplasmic domain in neurons
-
Fernández-Monreal M, Kang S, Phillips GR (2009) Gamma-protocadherin homophilic interaction and intracellular trafficking is controlled by the cytoplasmic domain in neurons. Mol Cell Neurosci 40:344-353.
-
(2009)
Mol Cell Neurosci
, vol.40
, pp. 344-353
-
-
Fernández-Monreal, M.1
Kang, S.2
Phillips, G.R.3
-
30
-
-
0022997931
-
In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64
-
Tamai M, et al. (1986) In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64. J Pharmacobiodyn 9:672-677.
-
(1986)
J Pharmacobiodyn
, vol.9
, pp. 672-677
-
-
Tamai, M.1
-
31
-
-
3142704315
-
Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor
-
Gupta-Rossi N, et al. (2004) Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor. J Cell Biol 166:73-83.
-
(2004)
J Cell Biol
, vol.166
, pp. 73-83
-
-
Gupta-Rossi, N.1
-
32
-
-
34147179336
-
TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain
-
Urra S, et al. (2007) TrkA receptor activation by nerve growth factor induces shedding of the p75 neurotrophin receptor followed by endosomal gamma-secretase-mediated release of the p75 intracellular domain. J Biol Chem 282:7606-7615.
-
(2007)
J Biol Chem
, vol.282
, pp. 7606-7615
-
-
Urra, S.1
-
33
-
-
33646892646
-
Dynasore, a cell-permeable inhibitor of dynamin
-
Macia E, et al. (2006) Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell 10:839-850.
-
(2006)
Dev Cell
, vol.10
, pp. 839-850
-
-
Macia, E.1
-
34
-
-
0020352681
-
Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts
-
Maxfield FR (1982) Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol 95:676-681.
-
(1982)
J Cell Biol
, vol.95
, pp. 676-681
-
-
Maxfield, F.R.1
-
35
-
-
27644593284
-
Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth
-
Moberg KH, Schelble S, Burdick SK, Hariharan IK (2005) Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth. Dev Cell 9:699-710.
-
(2005)
Dev Cell
, vol.9
, pp. 699-710
-
-
Moberg, K.H.1
Schelble, S.2
Burdick, S.K.3
Hariharan, I.K.4
-
36
-
-
27644498439
-
Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila
-
Thompson BJ, et al. (2005) Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev Cell 9:711-720.
-
(2005)
Dev Cell
, vol.9
, pp. 711-720
-
-
Thompson, B.J.1
-
37
-
-
27644568520
-
The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking
-
Vaccari T, Bilder D (2005) The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking. Dev Cell 9:687-698.
-
(2005)
Dev Cell
, vol.9
, pp. 687-698
-
-
Vaccari, T.1
Bilder, D.2
-
38
-
-
40849114907
-
Endosomal entry regulates Notch receptor activation in Drosophila melanogaster
-
Vaccari T, Lu H, Kanwar R, Fortini ME, Bilder D (2008) Endosomal entry regulates Notch receptor activation in Drosophila melanogaster. J Cell Biol 180:755-762.
-
(2008)
J Cell Biol
, vol.180
, pp. 755-762
-
-
Vaccari, T.1
Lu, H.2
Kanwar, R.3
Fortini, M.E.4
Bilder, D.5
-
39
-
-
0026646604
-
Amyloid beta-peptide is produced by cultured cells during normal metabolism
-
Haass C, et al. (1992) Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature 359:322-325.
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
-
40
-
-
11144350287
-
Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation
-
Sakata T, et al. (2004) Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation. Curr Biol 14:2228-2236.
-
(2004)
Curr Biol
, vol.14
, pp. 2228-2236
-
-
Sakata, T.1
-
41
-
-
19944389530
-
Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins
-
Wilkin MB, et al. (2004) Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins. Curr Biol 14:2237-2244.
-
(2004)
Curr Biol
, vol.14
, pp. 2237-2244
-
-
Wilkin, M.B.1
-
42
-
-
34447510955
-
Ligand binding and calcium influx induce distinct ectodomain/gamma- secretase-processing pathways of EphB2 receptor
-
Litterst C, et al. (2007) Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor. J Biol Chem 282:16155-16163.
-
(2007)
J Biol Chem
, vol.282
, pp. 16155-16163
-
-
Litterst, C.1
-
43
-
-
0034644836
-
Regulation of APP cleavage by alpha-, beta- and gamma-secretases
-
Nunan J, Small DH (2000) Regulation of APP cleavage by alpha-, beta- and gamma-secretases. FEBS Lett 483:6-10.
-
(2000)
FEBS Lett
, vol.483
, pp. 6-10
-
-
Nunan, J.1
Small, D.H.2
|