-
2
-
-
49849103726
-
Aneuploidy: Cells losing their balance
-
Torres EM, Williams BR, Amon A. Aneuploidy: cells losing their balance. Genetics 2008; 179:737-46.
-
(2008)
Genetics
, vol.179
, pp. 737-746
-
-
Torres, E.M.1
Williams, B.R.2
Amon, A.3
-
3
-
-
67649522162
-
Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis
-
Holland AJ, Cleveland DW. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol 2009; 10:478-87.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 478-487
-
-
Holland, A.J.1
Cleveland, D.W.2
-
4
-
-
35948943082
-
Aneuploidy: Instigator and inhibitor of tumorigenesis
-
Weaver BA, Cleveland DW. Aneuploidy: instigator and inhibitor of tumorigenesis. Cancer Res 2007; 67:10103-5.
-
(2007)
Cancer Res
, vol.67
, pp. 10103-10105
-
-
Weaver, B.A.1
Cleveland, D.W.2
-
5
-
-
69849107380
-
The life and miracles of kinetochores
-
Santaguida S, Musacchio A. The life and miracles of kinetochores. EMBO J 2009; 28:2511-31.
-
(2009)
EMBO J
, vol.28
, pp. 2511-2531
-
-
Santaguida, S.1
Musacchio, A.2
-
6
-
-
23744443826
-
Aneuploidy a matter of bad connections
-
Cimini D, Degrassi F. Aneuploidy a matter of bad connections. Trends Cell Biol 2005; 15:442-51.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 442-451
-
-
Cimini, D.1
Degrassi, F.2
-
7
-
-
27544434899
-
The kinetochore and cancer: What's the connection?
-
Yuen KW, Montpetit B, Hieter P. The kinetochore and cancer: what's the connection? Curr Op Cell Biol 2005; 17:576-82.
-
(2005)
Curr Op Cell Biol
, vol.17
, pp. 576-582
-
-
Yuen, K.W.1
Montpetit, B.2
Hieter, P.3
-
8
-
-
0030864009
-
HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis
-
Chen Y, Riley DJ, Chen PL, Lee WH. HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis. Mol Cell Biol 1997; 17:6049-56. (Pubitemid 27411113)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.10
, pp. 6049-6056
-
-
Chen, Y.1
Riley, D.J.2
Chen, P.-L.3
Lee, W.-H.4
-
9
-
-
34250006846
-
The Ndc80 complex: Hub of kinetochore activity
-
DOI 10.1016/j.febslet.2007.05.012, PII S0014579307005364, Vienna Special Issue: Molecular Machines
-
Ciferri C, Musacchio A, Petrovic A. The Ndc80 complex: hub of kinetochore activity. FEBS Lett 2007; 581:2862-9. (Pubitemid 46881153)
-
(2007)
FEBS Letters
, vol.581
, Issue.15
, pp. 2862-2869
-
-
Ciferri, C.1
Musacchio, A.2
Petrovic, A.3
-
11
-
-
0037183886
-
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2
-
Martin-Lluesma S, Stucke VM, Nigg EA. Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science 2002; 297:2267-70.
-
(2002)
Science
, vol.297
, pp. 2267-2270
-
-
Martin-Lluesma, S.1
Stucke, V.M.2
Nigg, E.A.3
-
12
-
-
0345526410
-
Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores
-
DeLuca J, Howell BJ, Canman JC, Hickey JM, Fang G, Salmon ED. Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores. Curr Biol 2003; 13:2103-9.
-
(2003)
Curr Biol
, vol.13
, pp. 2103-2109
-
-
DeLuca, J.1
Howell, B.J.2
Canman, J.C.3
Hickey, J.M.4
Fang, G.5
Salmon, E.D.6
-
13
-
-
1842529261
-
Identification of Two Novel Components of the Human NDC80 Kinetochore Complex
-
DOI 10.1074/jbc.M310224200
-
Bharadwaj R, Qi W, Yu H. Identification of two novel components of the human NDC80 kinetochore complex. J Biol Chem 2004; 279:13076-85. (Pubitemid 38445885)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.13
, pp. 13076-13085
-
-
Bharadwaj, R.1
Qi, W.2
Yu, H.3
-
14
-
-
4344610852
-
Timing and checkpoints in the regulation of mitotic progression
-
DOI 10.1016/j.devcel.2004.06.006, PII S1534580704002096
-
Meraldi P, Draviam VM, Sorger PK. Timing and checkpoints in the regulation of mitotic progression. Dev Cell 2004; 7:45-60. (Pubitemid 39172687)
-
(2004)
Developmental Cell
, vol.7
, Issue.1
, pp. 45-60
-
-
Meraldi, P.1
Draviam, V.M.2
Sorger, P.K.3
-
15
-
-
34447094967
-
A census of mitotic cancer genes: New insights into tumor cell biology and cancer therapy
-
DOI 10.1093/carcin/bgm019
-
Pèrez de Castro I, de Càrcer G, Malumbres M. A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy. Carcinogenesis 2007; 28:899-912. (Pubitemid 47072171)
-
(2007)
Carcinogenesis
, vol.28
, Issue.5
, pp. 899-912
-
-
Perez De Castro, I.1
De Carcer, G.2
Malumbres, M.3
-
16
-
-
77249101801
-
-
Oncomine™. Research Platform [https://www.oncomine.org].
-
Research Platform
-
-
-
17
-
-
20444457518
-
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
-
DOI 10.1172/JCI23412
-
Glinsky GV, Berezovska O, Glinskii AB. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005; 115:1503-21. (Pubitemid 40814659)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.6
, pp. 1503-1521
-
-
Glinsky, G.V.1
Berezovska, O.2
Glinskii, A.B.3
-
18
-
-
33751278753
-
Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis
-
DOI 10.1158/0008-5472.CAN-06-2137
-
Hayama S, Daigo Y, Kato T, Ishikawa N, Yamabuki T, Miyamoto M, et al. Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis. Cancer Res 2006; 66:10339-48. (Pubitemid 44799753)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10339-10348
-
-
Hayama, S.1
Daigo, Y.2
Kato, T.3
Ishikawa, N.4
Yamabuki, T.5
Miyamoto, M.6
Ito, T.7
Tsuchiya, E.8
Kondo, S.9
Nakamura, Y.10
-
19
-
-
70450278741
-
siRNA-mediated knockdown against CDCA1 and KNTC2, both frequently overexpressed in colorectal and gastric cancers, suppresses cell proliferation and induces apoptosis
-
Kaneko N, Miura K, Gu Z, Karasawa H, Ohnuma S, Sasaki H, et al. siRNA-mediated knockdown against CDCA1 and KNTC2, both frequently overexpressed in colorectal and gastric cancers, suppresses cell proliferation and induces apoptosis. Biochem Biophys Res Commun 2009; 390:1235-40.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 1235-1240
-
-
Kaneko, N.1
Miura, K.2
Gu, Z.3
Karasawa, H.4
Ohnuma, S.5
Sasaki, H.6
-
20
-
-
2342439525
-
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
-
DOI 10.1242/jcs.01006
-
Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS. Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2 and chromosome congression. J Cell Sci 2004; 117:1577-89. (Pubitemid 38559832)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.8
, pp. 1577-1589
-
-
Johnson, V.L.1
Scott, M.I.F.2
Holt, S.V.3
Hussein, D.4
Taylor, S.S.5
-
21
-
-
0029924241
-
Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites
-
Knudsen ES, Wang JY. Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites. J Biol Chem 1996; 271:8313-20.
-
(1996)
J Biol Chem
, vol.271
, pp. 8313-8320
-
-
Knudsen, E.S.1
Wang, J.Y.2
-
22
-
-
34547230356
-
Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria
-
Fu NY, Sukumaran SK, Yu VC. Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria. Proc Natl Acad Sci USA 2007; 104:10051-6.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10051-10056
-
-
Fu, N.Y.1
Sukumaran, S.K.2
Yu, V.C.3
-
23
-
-
0037157197
-
Degradation of human Aurora-A protein kinase is mediated by hCdh1
-
DOI 10.1016/S0014-5793(02)02711-4, PII S0014579302027114
-
Taguchi S, Honda K, Sugiura K, Yamaguchi A, Furukawa K, Urano T. Degradation of human Aurora-A protein kinase is mediated by hCdh1. FEBS Lett 2002; 519:59-65. (Pubitemid 34521992)
-
(2002)
FEBS Letters
, vol.519
, Issue.1-3
, pp. 59-65
-
-
Taguchi, S.-I.1
Honda, K.2
Sugiura, K.3
Yamaguchi, A.4
Furukawa, K.5
Urano, T.6
-
24
-
-
20344405716
-
Mechanism of aurora-B degradation and its dependency on intact KEN and A-boxes: Identification of an aneuploidy-promoting property
-
DOI 10.1128/MCB.25.12.4977-4992.2005
-
Nguyen HG, Chinnappan D, Urano T, Ravid K. Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property. Mol Cell Biol 2005; 25:4977-92. (Pubitemid 40781099)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.12
, pp. 4977-4992
-
-
Nguyen, H.G.1
Chinnappan, D.2
Urano, T.3
Ravid, K.4
-
25
-
-
30444449969
-
Mitosis: A matter of getting rid of the right protein at the right time
-
DOI 10.1016/j.tcb.2005.11.006, PII S0962892405003016
-
Pines J. Mitosis: a matter of getting rid of the right protein at the right time. Trends Cell Biol 2006; 16:55-63. (Pubitemid 43077095)
-
(2006)
Trends in Cell Biology
, vol.16
, Issue.1
, pp. 55-63
-
-
Pines, J.1
-
26
-
-
0042887146
-
Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells
-
DOI 10.1242/jcs.00645
-
Hori T, Haraguchi T, Hiraoka Y, Kimura H, Fukagawa T. Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J Cell Sci 2003; 116:3347-62. (Pubitemid 37038983)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.16
, pp. 3347-3362
-
-
Hori, T.1
Haraguchi, T.2
Hiraoka, Y.3
Kimura, H.4
Fukagawa, T.5
-
27
-
-
44149083326
-
Molecular architecture of the kinetochore-microtubule attachment site is conserved between point and regional centromeres
-
DOI 10.1083/jcb.200803027
-
Joglekar A, Bouck D, Finley K, Liu X, Wan Y, Berman J, et al. Molecular architecture of the kinetochore-microtubule attachment site is conserved between point and regional centromeres. J Cell Biol 2008; 181:587-94. (Pubitemid 351717506)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.4
, pp. 587-594
-
-
Joglekar, A.P.1
Bouck, D.2
Finley, K.3
Liu, X.4
Wan, Y.5
Berman, J.6
He, X.7
Salmon, E.D.8
Bloom, K.S.9
-
28
-
-
34247891773
-
The outer plate in vertebrate kinetochores is a flexible network with multiple microtubule interactions
-
DOI 10.1038/ncb1576, PII NCB1576
-
Dong Y, Vanden Beldt KJ, Meng X, Khodjakov A, McEwen BF. The outer plate in vertebrate kinetochores is a flexible network with multiple microtubule interactions. Nat Cell Biol 2007; 9:516-22. (Pubitemid 46696532)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.5
, pp. 516-522
-
-
Dong, Y.1
Vanden Beldt, K.J.2
Meng, X.3
Khodjakov, A.4
McEwen, B.F.5
-
29
-
-
65549149069
-
Protein architecture of the human kinetochore microtubule attachment site
-
Wan X, O'Quinn RP, Pierce HL, Joglekar AP, Gall WE, DeLuca JG, et al. Protein architecture of the human kinetochore microtubule attachment site. Cell 2009; 137:672-84.
-
(2009)
Cell
, vol.137
, pp. 672-684
-
-
Wan, X.1
O'Quinn, R.P.2
Pierce, H.L.3
Joglekar, A.P.4
Gall, W.E.5
DeLuca, J.G.6
-
30
-
-
32044443208
-
The retinoblastoma protein is required for Ras-induced oncogenic transformation
-
DOI 10.1128/MCB.26.4.1170-1182.2006
-
Williams JP, Stewart T, Li B, Mulloy R, Dimova D, Classon M. The retinoblastoma protein is required for Ras-induced oncogenic transformation. Mol Cell Biol 2006; 26:1170-82. (Pubitemid 43202547)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.4
, pp. 1170-1182
-
-
Williams, J.P.1
Stewart, T.2
Li, B.3
Mulloy, R.4
Dimova, D.5
Classon, M.6
-
31
-
-
34249109173
-
Evolutionarily Conserved Multisubunit RBL2/p130 and E2F4 Protein Complex Represses Human Cell Cycle-Dependent Genes in Quiescence
-
DOI 10.1016/j.molcel.2007.04.015, PII S1097276507002511
-
Litovchick L, Sadasivam S, Florens L, Zhu X, Swanson S, Velmurugan S, et al. Evolutionarily Conserved Multisubunit RBL2/p130 and E2F4 Protein Complex Represses Human Cell Cycle-Dependent Genes in Quiescence. Molecular Cell 2007; 26:539-51. (Pubitemid 46779093)
-
(2007)
Molecular Cell
, vol.26
, Issue.4
, pp. 539-551
-
-
Litovchick, L.1
Sadasivam, S.2
Florens, L.3
Zhu, X.4
Swanson, S.K.5
Velmurugan, S.6
Chen, R.7
Washburn, M.P.8
Liu, X.S.9
DeCaprio, J.A.10
-
32
-
-
34547457538
-
Identification of genes associated with tumorigenesis of retinoblastoma by microarray analysis
-
Chakraborty S, Khare S, Dorairaj SK, Prabhakaran VC, Prakash DR, Kumar A. Identification of genes associated with tumorigenesis of retinoblastoma by microarray analysis. Genomics 2007; 90:344-53.
-
(2007)
Genomics
, vol.90
, pp. 344-353
-
-
Chakraborty, S.1
Khare, S.2
Dorairaj, S.K.3
Prabhakaran, V.C.4
Prakash, D.R.5
Kumar, A.6
-
33
-
-
33750220492
-
RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
-
DOI 10.1186/1476-4598-5-38
-
Iovino F, Lentini L, Amato A, Di Leonardo A. RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol Cancer 2006; 5:38. (Pubitemid 44604825)
-
(2006)
Molecular Cancer
, vol.5
, pp. 38
-
-
Iovino, F.1
Lentini, L.2
Amato, A.3
Di Leonardo, A.4
-
34
-
-
70749128701
-
RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation
-
Amato A, Lentini L, Schillaci T, Iovino F, Di Leonardo A. RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation. BMC Cell Biol 2009; 10:79.
-
(2009)
BMC Cell Biol
, vol.10
, pp. 79
-
-
Amato, A.1
Lentini, L.2
Schillaci, T.3
Iovino, F.4
Di Leonardo, A.5
-
35
-
-
4043093341
-
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
-
DOI 10.1038/nature02820
-
Hernando E, Nahlé Z, Juan G, Diaz-Rodriguez E, Alaminos M, Hemann M, et al. Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature 2004; 430:797-802. (Pubitemid 39071352)
-
(2004)
Nature
, vol.430
, Issue.7001
, pp. 797-802
-
-
Hernando, E.1
Nahle, Z.2
Juan, G.3
Diaz-Rodriguez, E.4
Alaminos, M.5
Hemann, M.6
Michel, L.7
Mittal, V.8
Gerald, W.9
Benezra, R.10
Lowe, S.W.11
Cordon-Cardo, C.12
-
36
-
-
33646250688
-
The retinoblastoma protein regulates pericentric heterochromatin
-
Isaac CE, Francis SM, Martens AL, Julian LM, Seifried LA, Erdmann N, et al. The retinoblastoma protein regulates pericentric heterochromatin. Mol Cell Biol 2006; 26:3659-71.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3659-3671
-
-
Isaac, C.E.1
Francis, S.M.2
Martens, A.L.3
Julian, L.M.4
Seifried, L.A.5
Erdmann, N.6
-
37
-
-
77954498022
-
Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive
-
Coschi CH, Martens AL, Ritchie K, Francis SM, Chakrabarti S, Berube NG, et al. Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive. Genes Dev 2010; 24:1351-63.
-
(2010)
Genes Dev
, vol.24
, pp. 1351-1363
-
-
Coschi, C.H.1
Martens, A.L.2
Ritchie, K.3
Francis, S.M.4
Chakrabarti, S.5
Berube, N.G.6
-
38
-
-
77954522274
-
Loss of pRB causes centromere dysfunction and chromosomal instability
-
Manning AL, Longworth MS, Dyson NJ. Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev 2010; 24:1364-76.
-
(2010)
Genes Dev
, vol.24
, pp. 1364-1376
-
-
Manning, A.L.1
Longworth, M.S.2
Dyson, N.J.3
-
39
-
-
0035972237
-
Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells
-
Cimini D, Howell B, Maddox P, Khodjakov A, Degrassi F, Salmon ED. Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells. J Cell Biol 2001; 153:517-27.
-
(2001)
J Cell Biol
, vol.153
, pp. 517-527
-
-
Cimini, D.1
Howell, B.2
Maddox, P.3
Khodjakov, A.4
Degrassi, F.5
Salmon, E.D.6
-
41
-
-
60749109846
-
Cell cycle, CDKs and cancer: A changing paradigm
-
Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009; 9:153-66.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
42
-
-
17244363408
-
Molecular organization of the Ndc80 complex, an essential kinetochore component
-
Wei RR, Sorger PK, Harrison SC. Molecular organization of the Ndc80 complex, an essential kinetochore component. Proc Natl Acad Sci USA 2005; 102:5363-7.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5363-5367
-
-
Wei, R.R.1
Sorger, P.K.2
Harrison, S.C.3
-
43
-
-
23844460843
-
Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore
-
DOI 10.1074/jbc.M504070200
-
Ciferri C, De Luca J, Monzani S, Ferrari KJ, Ristic D, Wyman C, et al. Architecture of the human ndc80-Hec 1 complex, a critical constituent of the outer kinetochore. J Biol Chem 2005; 280:29088-95. (Pubitemid 41161359)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.32
, pp. 29088-29095
-
-
Ciferri, C.1
De Lucall, J.2
Monzani, S.3
Ferrari, K.J.4
Ristic, D.5
Wyman, C.6
Stark, H.7
Kilmartin, J.8
Salmon, E.D.9
Musacchio, A.10
-
44
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
|