메뉴 건너뛰기




Volumn 19, Issue 11, 2010, Pages 987-993

Modulation of metallothionein isoforms is associated with collagen deposition in proliferating keloid fibroblasts in vitro

Author keywords

Keloid pathogenesis; Metallothionein isoforms; Proliferation; Silencing MT 2A gene; Ultrastructure

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; METALLOTHIONEIN; METALLOTHIONEIN I; METALLOTHIONEIN II; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77958546489     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2010.01124.x     Document Type: Article
Times cited : (19)

References (46)
  • 2
    • 33751100885 scopus 로고    scopus 로고
    • Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways
    • Zhang Q, Kelly A P, Wang L et al. Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways. J Invest Dermatol 2006: 126: 2607-2613.
    • (2006) J Invest Dermatol , vol.126 , pp. 2607-2613
    • Zhang, Q.1    Kelly, A.P.2    Wang, L.3
  • 3
    • 44949206532 scopus 로고    scopus 로고
    • Genetic susceptibility to keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans
    • Brown J J, Ollier W, Arscott G et al. Genetic susceptibility to keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans. Exp Dermatol 2008: 17: 610-613.
    • (2008) Exp Dermatol , vol.17 , pp. 610-613
    • Brown, J.J.1    Ollier, W.2    Arscott, G.3
  • 4
    • 67349158299 scopus 로고    scopus 로고
    • Keloid scarring: bench and bedside
    • Seifert O, Mrowietz U. Keloid scarring: bench and bedside. Arch Dermatol Res 2009: 301: 259-272.
    • (2009) Arch Dermatol Res , vol.301 , pp. 259-272
    • Seifert, O.1    Mrowietz, U.2
  • 5
    • 77958568419 scopus 로고    scopus 로고
    • Mechanisms of MAPK pathway mediating TGF-beta(1)/Smad signal in keloid fibroblasts
    • He S, Liu X, Yang Y et al. Mechanisms of MAPK pathway mediating TGF-beta(1)/Smad signal in keloid fibroblasts. Br J Dermatol 2010: 162: 533-546.
    • (2010) Br J Dermatol , vol.162 , pp. 533-546
    • He, S.1    Liu, X.2    Yang, Y.3
  • 6
    • 70549087922 scopus 로고    scopus 로고
    • Telomere shortening may be associated with human keloids
    • De Felice B, Wilson R R, Nacca M. Telomere shortening may be associated with human keloids. BMC Med Genet 2009: 10: 110.
    • (2009) BMC Med Genet , vol.10 , pp. 110
    • De Felice, B.1    Wilson, R.R.2    Nacca, M.3
  • 7
    • 70349498670 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in keloids: a clinicopathologic study
    • Salem A, Assaf M, Helmy A et al. Role of vascular endothelial growth factor in keloids: a clinicopathologic study. Int J Dermatol 2009: 48: 1071-1077.
    • (2009) Int J Dermatol , vol.48 , pp. 1071-1077
    • Salem, A.1    Assaf, M.2    Helmy, A.3
  • 8
    • 0029980524 scopus 로고    scopus 로고
    • Increased proliferation in keloid fibroblasts wounded in vitro
    • Calderon M, Lawrence W T, Banes A J. Increased proliferation in keloid fibroblasts wounded in vitro. J Surg Res 1996: 61: 343-347.
    • (1996) J Surg Res , vol.61 , pp. 343-347
    • Calderon, M.1    Lawrence, W.T.2    Banes, A.J.3
  • 9
    • 0031598567 scopus 로고    scopus 로고
    • p53 and apoptosis alterations in keloids and keloid fibroblasts
    • Ladin D A, Hou Z, Patel D et al. p53 and apoptosis alterations in keloids and keloid fibroblasts. Wound Repair Regen 1998: 6: 28-37.
    • (1998) Wound Repair Regen , vol.6 , pp. 28-37
    • Ladin, D.A.1    Hou, Z.2    Patel, D.3
  • 10
  • 11
    • 0008434168 scopus 로고    scopus 로고
    • Nuclear localization of metallothionein during cell proliferation and differentiation
    • Cherian M G, Apostolova M D. Nuclear localization of metallothionein during cell proliferation and differentiation. Cell Mol Biol (Noisy-le-grand) 2000: 46: 347-356.
    • (2000) Cell Mol Biol (Noisy-le-grand) , vol.46 , pp. 347-356
    • Cherian, M.G.1    Apostolova, M.D.2
  • 12
    • 0028836796 scopus 로고
    • Cell cycle regulation of metallothionein in human colonic cancer cells
    • Nagel W W, Vallee B L. Cell cycle regulation of metallothionein in human colonic cancer cells. Proc Natl Acad Sci U S A 1995: 92: 579-583.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 579-583
    • Nagel, W.W.1    Vallee, B.L.2
  • 13
    • 0030711622 scopus 로고    scopus 로고
    • Metallothionein accretion in human hepatic cells is linked to cellular proliferation
    • Studer R, Vogt C P, Cavigelli M, Hunziker P E, Kagi J H. Metallothionein accretion in human hepatic cells is linked to cellular proliferation. Biochem J 1997: 328: 63-67.
    • (1997) Biochem J , vol.328 , pp. 63-67
    • Studer, R.1    Vogt, C.P.2    Cavigelli, M.3    Hunziker, P.E.4    Kagi, J.H.5
  • 14
    • 33644851283 scopus 로고    scopus 로고
    • Up-regulation of metallothionein isoforms in keloid keratinocytes
    • Lim D, Phan T T, Yip G W, Bay B H. Up-regulation of metallothionein isoforms in keloid keratinocytes. Int J Mol Med 2006: 17: 385-389.
    • (2006) Int J Mol Med , vol.17 , pp. 385-389
    • Lim, D.1    Phan, T.T.2    Yip, G.W.3    Bay, B.H.4
  • 16
    • 33947463103 scopus 로고
    • A cadmium protein from equine kidney cortex
    • Margoshes M, Vallee B L. A cadmium protein from equine kidney cortex. J Am Chem Soc 1957: 79: 4813-4814.
    • (1957) J Am Chem Soc , vol.79 , pp. 4813-4814
    • Margoshes, M.1    Vallee, B.L.2
  • 17
    • 0029060897 scopus 로고
    • The function of metallothionein
    • Vallee B L. The function of metallothionein. Neurochem Int 1995: 27: 23-33.
    • (1995) Neurochem Int , vol.27 , pp. 23-33
    • Vallee, B.L.1
  • 19
    • 0038406726 scopus 로고    scopus 로고
    • Metallothioneins: new functional and structural insights
    • Vasak M, Hasler D W. Metallothioneins: new functional and structural insights. Curr Opin Chem Biol 2000: 4: 177-183.
    • (2000) Curr Opin Chem Biol , vol.4 , pp. 177-183
    • Vasak, M.1    Hasler, D.W.2
  • 20
    • 0345276580 scopus 로고    scopus 로고
    • Metallothioneins in human tumors and potential roles in carcinogenesis
    • Cherian M G, Jayasurya A, Bay B H. Metallothioneins in human tumors and potential roles in carcinogenesis. Mutat Res 2003: 533: 201-209.
    • (2003) Mutat Res , vol.533 , pp. 201-209
    • Cherian, M.G.1    Jayasurya, A.2    Bay, B.H.3
  • 21
    • 0033782829 scopus 로고    scopus 로고
    • Proliferative potential in nasopharyngeal carcinoma: correlations with metallothionein expression and tissue zinc levels
    • Jayasurya A, Bay B H, Yap W M, Tan N G, Tan B K. Proliferative potential in nasopharyngeal carcinoma: correlations with metallothionein expression and tissue zinc levels. Carcinogenesis 2000: 21: 1809-1812.
    • (2000) Carcinogenesis , vol.21 , pp. 1809-1812
    • Jayasurya, A.1    Bay, B.H.2    Yap, W.M.3    Tan, N.G.4    Tan, B.K.5
  • 22
    • 0036200075 scopus 로고    scopus 로고
    • Metallothionein 2A expression is associated with cell proliferation in breast cancer
    • Jin R, Chow V T, Tan P H, Dheen S T, Duan W, Bay B H. Metallothionein 2A expression is associated with cell proliferation in breast cancer. Carcinogenesis 2002: 23: 81-86.
    • (2002) Carcinogenesis , vol.23 , pp. 81-86
    • Jin, R.1    Chow, V.T.2    Tan, P.H.3    Dheen, S.T.4    Duan, W.5    Bay, B.H.6
  • 23
    • 0032903908 scopus 로고    scopus 로고
    • The transcriptional program in the response of human fibroblasts to serum
    • Iyer V R, Eisen M B, Ross D T et al. The transcriptional program in the response of human fibroblasts to serum. Science 1999: 283: 83-87.
    • (1999) Science , vol.283 , pp. 83-87
    • Iyer, V.R.1    Eisen, M.B.2    Ross, D.T.3
  • 24
    • 0036086236 scopus 로고    scopus 로고
    • Fibroblasts cocultured with keloid keratinocytes: normal fibroblasts secrete collagen in a keloidlike manner
    • Lim I J, Phan T T, Bay B H et al. Fibroblasts cocultured with keloid keratinocytes: normal fibroblasts secrete collagen in a keloidlike manner. Am J Physiol Cell Physiol 2002: 283: C212-C222.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Lim, I.J.1    Phan, T.T.2    Bay, B.H.3
  • 25
    • 0029877578 scopus 로고    scopus 로고
    • Isoform-specific expression of metallothionein mRNA in the developing and adult human kidney
    • Mididoddi S, McGuirt J P, Sens M A, Todd J H, Sens D A. Isoform-specific expression of metallothionein mRNA in the developing and adult human kidney. Toxicol Lett 1996: 85: 17-27.
    • (1996) Toxicol Lett , vol.85 , pp. 17-27
    • Mididoddi, S.1    McGuirt, J.P.2    Sens, M.A.3    Todd, J.H.4    Sens, D.A.5
  • 26
    • 50149094483 scopus 로고    scopus 로고
    • Specific inhibitor of MEK-mediated cross-talk between ERK and p38 MAPK during differentiation of human osteosarcoma cells
    • Shimo T, Matsumura S, Ibaragi S et al. Specific inhibitor of MEK-mediated cross-talk between ERK and p38 MAPK during differentiation of human osteosarcoma cells. J Cell Commun Signal 2007: 1: 103-111.
    • (2007) J Cell Commun Signal , vol.1 , pp. 103-111
    • Shimo, T.1    Matsumura, S.2    Ibaragi, S.3
  • 27
    • 40349091710 scopus 로고    scopus 로고
    • Differential effects of hyaluronan and its fragments on fibroblasts: relation to wound healing
    • David-Raoudi M, Tranchepain F, Deschrevel B et al. Differential effects of hyaluronan and its fragments on fibroblasts: relation to wound healing. Wound Repair Regen 2008: 16: 274-287.
    • (2008) Wound Repair Regen , vol.16 , pp. 274-287
    • David-Raoudi, M.1    Tranchepain, F.2    Deschrevel, B.3
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak K J, Schmittgen T D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001: 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 31
    • 4344682543 scopus 로고    scopus 로고
    • Activation of NFkappaB signal pathways in keloid fibroblasts
    • Messadi D V, Doung H S, Zhang Q et al. Activation of NFkappaB signal pathways in keloid fibroblasts. Arch Dermatol Res 2004: 296: 125-133.
    • (2004) Arch Dermatol Res , vol.296 , pp. 125-133
    • Messadi, D.V.1    Doung, H.S.2    Zhang, Q.3
  • 32
    • 0035955458 scopus 로고    scopus 로고
    • Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells
    • Garrett S H, Belcastro M, Sens M A, Somji S, Sens D A. Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells. J Toxicol Environ Health A 2001: 64: 343-355.
    • (2001) J Toxicol Environ Health A , vol.64 , pp. 343-355
    • Garrett, S.H.1    Belcastro, M.2    Sens, M.A.3    Somji, S.4    Sens, D.A.5
  • 33
    • 0344496708 scopus 로고    scopus 로고
    • The changes of hepatic metallothionein synthesis and the hepatic damage induced by starvation in mice
    • Sogawa N, Sogawa C A, Fukuoka H et al. The changes of hepatic metallothionein synthesis and the hepatic damage induced by starvation in mice. Methods Find Exp Clin Pharmacol 2003: 25: 601-606.
    • (2003) Methods Find Exp Clin Pharmacol , vol.25 , pp. 601-606
    • Sogawa, N.1    Sogawa, C.A.2    Fukuoka, H.3
  • 34
    • 0031759474 scopus 로고    scopus 로고
    • Characterization of horse kidney metallothionein isoforms by electrospray MS and reversed-phase HPLC-electrospray MS
    • Chassaigne H, Lobinski R. Characterization of horse kidney metallothionein isoforms by electrospray MS and reversed-phase HPLC-electrospray MS. Analyst 1998: 123: 2125-2130.
    • (1998) Analyst , vol.123 , pp. 2125-2130
    • Chassaigne, H.1    Lobinski, R.2
  • 35
    • 0033659306 scopus 로고    scopus 로고
    • Metallothionein biosynthesis in human RBC precursors
    • Rahman M T, Vandingenen A, De L M. Metallothionein biosynthesis in human RBC precursors. Cell Physiol Biochem 2000: 10: 237-242.
    • (2000) Cell Physiol Biochem , vol.10 , pp. 237-242
    • Rahman, M.T.1    Vandingenen, A.2    De, L.M.3
  • 36
    • 33846556197 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)-beta1-induced collagen synthesis
    • Sandulache V C, Parekh A, Li-Korotky H, Dohar J E, Hebda P A. Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)-beta1-induced collagen synthesis. Wound Repair Regen 2007: 15: 122-133.
    • (2007) Wound Repair Regen , vol.15 , pp. 122-133
    • Sandulache, V.C.1    Parekh, A.2    Li-Korotky, H.3    Dohar, J.E.4    Hebda, P.A.5
  • 39
    • 34548321204 scopus 로고    scopus 로고
    • NF-ΚB and the hepatic inflammation- fibrosis-cancer axis
    • Elsharkawy A M, Mann D A. NF-ΚB and the hepatic inflammation- fibrosis-cancer axis. Hepatology 2007: 46: 590-597.
    • (2007) Hepatology , vol.46 , pp. 590-597
    • Elsharkawy, A.M.1    Mann, D.A.2
  • 40
    • 0037081794 scopus 로고    scopus 로고
    • Metallothionein modulates lipopolysaccharide-stimulated tumor necrosis factor expression in mouse peritoneal macrophages
    • Kanekiyo M, Itoh N, Kawasaki A et al. Metallothionein modulates lipopolysaccharide-stimulated tumor necrosis factor expression in mouse peritoneal macrophages. Biochem J 2002: 361: 363-369.
    • (2002) Biochem J , vol.361 , pp. 363-369
    • Kanekiyo, M.1    Itoh, N.2    Kawasaki, A.3
  • 41
    • 33845966735 scopus 로고    scopus 로고
    • Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells
    • Chen F, Lu Y, Castranova V, Li Z, Karin M. Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells. J Biol Chem 2006: 281: 37142-37149.
    • (2006) J Biol Chem , vol.281 , pp. 37142-37149
    • Chen, F.1    Lu, Y.2    Castranova, V.3    Li, Z.4    Karin, M.5
  • 42
    • 32244433433 scopus 로고    scopus 로고
    • Metallothionein and liver cell regeneration
    • Cherian M G, Kang Y J. Metallothionein and liver cell regeneration. Exp Biol Med (Maywood) 2006: 231: 138-144.
    • (2006) Exp Biol Med (Maywood) , vol.231 , pp. 138-144
    • Cherian, M.G.1    Kang, Y.J.2
  • 43
    • 0021827463 scopus 로고
    • Biochemical composition of the connective tissue in keloids and analysis of collagen metabolism in keloid fibroblast cultures
    • Abergel R P, Pizzurro D, Meeker C A et al. Biochemical composition of the connective tissue in keloids and analysis of collagen metabolism in keloid fibroblast cultures. J Invest Dermatol 1985: 84: 384-390.
    • (1985) J Invest Dermatol , vol.84 , pp. 384-390
    • Abergel, R.P.1    Pizzurro, D.2    Meeker, C.A.3
  • 45
    • 0033635399 scopus 로고    scopus 로고
    • Distribution of zinc-binding metallothionein in cirrhotic liver of rats administered zinc
    • Sato S, Shimizu M, Hosokawa T et al. Distribution of zinc-binding metallothionein in cirrhotic liver of rats administered zinc. Pharmacol Toxicol 2000: 87: 292-296.
    • (2000) Pharmacol Toxicol , vol.87 , pp. 292-296
    • Sato, S.1    Shimizu, M.2    Hosokawa, T.3
  • 46
    • 85047692717 scopus 로고    scopus 로고
    • Alcohol-induced myocardial fibrosis in metallothionein-null mice: prevention by zinc supplementation
    • Wang L, Zhou Z, Saari J T, Kang Y J. Alcohol-induced myocardial fibrosis in metallothionein-null mice: prevention by zinc supplementation. Am J Pathol 2005: 167: 337-344.
    • (2005) Am J Pathol , vol.167 , pp. 337-344
    • Wang, L.1    Zhou, Z.2    Saari, J.T.3    Kang, Y.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.