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Volumn 269, Issue 1, 2011, Pages 70-78

Mathematical modeling of allergy and specific immunotherapy: Th1-Th2-Treg interactions

Author keywords

Desensitization; Nonlinear dynamics; Regulatory T cells

Indexed keywords

ALLERGEN; CYTOKINE;

EID: 77958532494     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2010.10.013     Document Type: Article
Times cited : (40)

References (56)
  • 2
    • 34047163404 scopus 로고    scopus 로고
    • Mechanisms of allergen-specific immunotherapy
    • Akdis M., Akdis C. Mechanisms of allergen-specific immunotherapy. J. Allergy Clin. Immunol. 2007, 119(4):780-789.
    • (2007) J. Allergy Clin. Immunol. , vol.119 , Issue.4 , pp. 780-789
    • Akdis, M.1    Akdis, C.2
  • 3
    • 2942685507 scopus 로고    scopus 로고
    • Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
    • Akdis M., Verhagen J., Taylor A., Karamloo F., Karagiannidis C., Crameri R., Thunberg S., Deniz G., Valenta R., Fiebig H., et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J. Exp. Med. 2004, 199(11):1567-1575.
    • (2004) J. Exp. Med. , vol.199 , Issue.11 , pp. 1567-1575
    • Akdis, M.1    Verhagen, J.2    Taylor, A.3    Karamloo, F.4    Karagiannidis, C.5    Crameri, R.6    Thunberg, S.7    Deniz, G.8    Valenta, R.9    Fiebig, H.10
  • 4
    • 79151478290 scopus 로고    scopus 로고
    • Self-tolerance and autoimmunity in a regulatory T cell model
    • doi:
    • Alexander, H., Wahl, L., 2010. Self-tolerance and autoimmunity in a regulatory T cell model. Bull. Math. Biol. 1-39, doi:. http://10.1007/s11538-010-9519-2.
    • (2010) Bull. Math. Biol. , pp. 1-39
    • Alexander, H.1    Wahl, L.2
  • 5
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature 1998, 392(6673):245-252.
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 7
    • 0009813297 scopus 로고    scopus 로고
    • Modeling Th1-Th2 regulation, allergy and hyposensitization
    • World Scientific, Singapore, F. Bagnoli, S. Ruffo (Eds.)
    • Behn U., Dambeck H., Metzner G. Modeling Th1-Th2 regulation, allergy and hyposensitization. Dynamical Modeling in Biotechnology 2001, 227-247. World Scientific, Singapore. F. Bagnoli, S. Ruffo (Eds.).
    • (2001) Dynamical Modeling in Biotechnology , pp. 227-247
    • Behn, U.1    Dambeck, H.2    Metzner, G.3
  • 8
    • 0034974036 scopus 로고    scopus 로고
    • Th1 or Th2: how an appropriate T helper response can be made
    • Bergmann C., Van Hemmen J., Segel L. Th1 or Th2: how an appropriate T helper response can be made. Bull. Math. Biol. 2001, 63(3):405-430.
    • (2001) Bull. Math. Biol. , vol.63 , Issue.3 , pp. 405-430
    • Bergmann, C.1    Van Hemmen, J.2    Segel, L.3
  • 9
    • 77949514455 scopus 로고    scopus 로고
    • The danger is growing! A new paradigm for immune system activation and peripheral tolerance
    • Bewick S., Yang R., Zhang M. The danger is growing! A new paradigm for immune system activation and peripheral tolerance. PloS One 2009, 4(12):e8112.
    • (2009) PloS One , vol.4 , Issue.12
    • Bewick, S.1    Yang, R.2    Zhang, M.3
  • 10
    • 0031736285 scopus 로고    scopus 로고
    • Allergen immunotherapy: therapeutic vaccines for allergic diseases A WHO position paper
    • Bousquet J., Lockey R., Malling H. Allergen immunotherapy: therapeutic vaccines for allergic diseases A WHO position paper. J. Allergy Clin. Immunol. 1998, 102(4):558-562.
    • (1998) J. Allergy Clin. Immunol. , vol.102 , Issue.4 , pp. 558-562
    • Bousquet, J.1    Lockey, R.2    Malling, H.3
  • 11
    • 33744534672 scopus 로고    scopus 로고
    • Regulatory T cell adjustment of quorum growth thresholds and the control of local immune responses
    • Burroughs N.J., Miguel Paz Mendes de Oliveira B., Adrego Pinto A. Regulatory T cell adjustment of quorum growth thresholds and the control of local immune responses. J. Theor. Biol. 2006, 241(1):134-141.
    • (2006) J. Theor. Biol. , vol.241 , Issue.1 , pp. 134-141
    • Burroughs, N.J.1    Miguel Paz Mendes de Oliveira, B.2    Adrego Pinto, A.3
  • 13
    • 0029102015 scopus 로고
    • The ontogeny of class-regulation of CD4+ T lymphocyte populations
    • Carneiro J., Stewart J., Coutinho A., Coutinho G. The ontogeny of class-regulation of CD4+ T lymphocyte populations. Int. Immunol. 1995, 7(8):1265-1277.
    • (1995) Int. Immunol. , vol.7 , Issue.8 , pp. 1265-1277
    • Carneiro, J.1    Stewart, J.2    Coutinho, A.3    Coutinho, G.4
  • 14
    • 0030858138 scopus 로고    scopus 로고
    • Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    • Cella M., Engering A., Pinet V., Pieters J., Lanzavecchia A. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 1997, 388(6644):782-787.
    • (1997) Nature , vol.388 , Issue.6644 , pp. 782-787
    • Cella, M.1    Engering, A.2    Pinet, V.3    Pieters, J.4    Lanzavecchia, A.5
  • 15
    • 1642373911 scopus 로고    scopus 로고
    • Tolerance mechanisms and recent progress
    • Elsevier
    • Chan C., Lechler R., George A. Tolerance mechanisms and recent progress. Transplant 2004, vol. 36:561-569. Elsevier.
    • (2004) Transplant , vol.36 , pp. 561-569
    • Chan, C.1    Lechler, R.2    George, A.3
  • 16
    • 44449096726 scopus 로고    scopus 로고
    • IL-10: the master regulator of immunity to infection
    • Couper K.N., Blount D.G., Riley E.M. IL-10: the master regulator of immunity to infection. J. Immunol. 2008, 180(9):5771-5777.
    • (2008) J. Immunol. , vol.180 , Issue.9 , pp. 5771-5777
    • Couper, K.N.1    Blount, D.G.2    Riley, E.M.3
  • 17
    • 48349128041 scopus 로고    scopus 로고
    • Advantages and disadvantages of accelerated immunotherapy schedules
    • Cox L. Advantages and disadvantages of accelerated immunotherapy schedules. J. Allergy Clin. Immunol. 2008, 122(2):432-434.
    • (2008) J. Allergy Clin. Immunol. , vol.122 , Issue.2 , pp. 432-434
    • Cox, L.1
  • 18
    • 46749126890 scopus 로고    scopus 로고
    • Adaptive Foxp3+ regulatory T cell-dependent and-independent control of allergic inflammation
    • Curotto de Lafaille M.A., Kutchukhidze N., Shen S., Ding Y., Yee H., Lafaille J.J. Adaptive Foxp3+ regulatory T cell-dependent and-independent control of allergic inflammation. Immunity 2008, 29(1):114-126.
    • (2008) Immunity , vol.29 , Issue.1 , pp. 114-126
    • Curotto de Lafaille, M.A.1    Kutchukhidze, N.2    Shen, S.3    Ding, Y.4    Yee, H.5    Lafaille, J.J.6
  • 20
    • 77954656225 scopus 로고    scopus 로고
    • Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma
    • Eftimie, R., Bramson, J.L., Earn, D.J.D., 2010. Modeling anti-tumor Th1 and Th2 immunity in the rejection of melanoma. J. Theor. Biol. 265 (3), 467-480.
    • (2010) J. Theor. Biol. , vol.265 , Issue.3 , pp. 467-480
    • Eftimie, R.1    Bramson, J.L.2    Earn, D.J.D.3
  • 21
    • 0032458655 scopus 로고    scopus 로고
    • Bee sting allergy in beekeepers
    • Eich-Wanger C., Müller U.R. Bee sting allergy in beekeepers. Clin. Exp. Allergy 1998, 28(10):1292-1298.
    • (1998) Clin. Exp. Allergy , vol.28 , Issue.10 , pp. 1292-1298
    • Eich-Wanger, C.1    Müller, U.R.2
  • 22
    • 46249122835 scopus 로고    scopus 로고
    • Optimality analysis of Th1/Th2 immune responses during microparasite-macroparasite co-infection, with epidemiological feedbacks
    • Fenton A., Lamb T., Graham A.L. Optimality analysis of Th1/Th2 immune responses during microparasite-macroparasite co-infection, with epidemiological feedbacks. Parasitology 2008, 135(7):841-853.
    • (2008) Parasitology , vol.135 , Issue.7 , pp. 841-853
    • Fenton, A.1    Lamb, T.2    Graham, A.L.3
  • 24
    • 0032989752 scopus 로고    scopus 로고
    • Th1/Th2 differentiation and cross-regulation
    • Fishman M.A., Perelson A.S. Th1/Th2 differentiation and cross-regulation. Bull. Math. Biol. 1999, 61(3):403-436.
    • (1999) Bull. Math. Biol. , vol.61 , Issue.3 , pp. 403-436
    • Fishman, M.A.1    Perelson, A.S.2
  • 25
    • 0030293835 scopus 로고    scopus 로고
    • Modeling immunotherapy for allergy
    • Fishman M.A., Segel L.A. Modeling immunotherapy for allergy. Bull. Math. Biol. 1996, 58(6):1099-1121.
    • (1996) Bull. Math. Biol. , vol.58 , Issue.6 , pp. 1099-1121
    • Fishman, M.A.1    Segel, L.A.2
  • 26
    • 48449104143 scopus 로고    scopus 로고
    • A population dynamics analysis of the interaction between adaptive regulatory T cells and antigen presenting cells
    • Fouchet D., Regoes R. A population dynamics analysis of the interaction between adaptive regulatory T cells and antigen presenting cells. PLoS One 2008, 3(5):e2306.
    • (2008) PLoS One , vol.3 , Issue.5
    • Fouchet, D.1    Regoes, R.2
  • 27
    • 47949107183 scopus 로고    scopus 로고
    • The development of allergic inflammation
    • Galli S., Tsai M., Piliponsky A. The development of allergic inflammation. Nature 2008, 454(7203):445-454.
    • (2008) Nature , vol.454 , Issue.7203 , pp. 445-454
    • Galli, S.1    Tsai, M.2    Piliponsky, A.3
  • 28
    • 18144408736 scopus 로고    scopus 로고
    • Cell fates as high-dimensional attractor states of a complex gene regulatory network
    • Huang S., Eichler G., Bar-Yam Y., Ingber D.E. Cell fates as high-dimensional attractor states of a complex gene regulatory network. Phys. Rev. Lett. 2005, 94(12):128701.1-128701.4.
    • (2005) Phys. Rev. Lett. , vol.94 , Issue.12
    • Huang, S.1    Eichler, G.2    Bar-Yam, Y.3    Ingber, D.E.4
  • 29
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin 10-producing: nonproliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • Jonuleit H., Schmitt E., Schuler G., Knop J., Enk A. Induction of interleukin 10-producing: nonproliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 2000, 192(9):1213-1222.
    • (2000) J. Exp. Med. , vol.192 , Issue.9 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.5
  • 30
    • 77952672188 scopus 로고    scopus 로고
    • Emergent group dynamics governed by regulatory cells produce a robust primary T cell response
    • Kim P.S., Lee P.P., Levy D. Emergent group dynamics governed by regulatory cells produce a robust primary T cell response. Bull. Math. Biol. 2010, 72(3):611-644.
    • (2010) Bull. Math. Biol. , vol.72 , Issue.3 , pp. 611-644
    • Kim, P.S.1    Lee, P.P.2    Levy, D.3
  • 31
    • 0035838981 scopus 로고    scopus 로고
    • Regulation of T cell immunity by dendritic cells
    • Lanzavecchia A., Sallusto F. Regulation of T cell immunity by dendritic cells. Cell 2001, 106(3):263-266.
    • (2001) Cell , vol.106 , Issue.3 , pp. 263-266
    • Lanzavecchia, A.1    Sallusto, F.2
  • 32
    • 17044454394 scopus 로고    scopus 로고
    • Inverse correlation between the incidences of autoimmune disease and infection predicted by a model of T cell mediated tolerance
    • León K., Faro J., Lage A., Carneiro J. Inverse correlation between the incidences of autoimmune disease and infection predicted by a model of T cell mediated tolerance. J. Autoimmun. 2004, 22(1):31-42.
    • (2004) J. Autoimmun. , vol.22 , Issue.1 , pp. 31-42
    • León, K.1    Faro, J.2    Lage, A.3    Carneiro, J.4
  • 33
    • 0034700299 scopus 로고    scopus 로고
    • Modelling T-cell-mediated suppression dependent on interactions in multicellular conjugates
    • León K., Perez R., Lage A., Jorge A. Modelling T-cell-mediated suppression dependent on interactions in multicellular conjugates. J. Theor. Biol. 2000, 207(2):231-254.
    • (2000) J. Theor. Biol. , vol.207 , Issue.2 , pp. 231-254
    • León, K.1    Perez, R.2    Lage, A.3    Jorge, A.4
  • 34
    • 0035702380 scopus 로고    scopus 로고
    • Modeling the influence of TH1-and TH2-type cells in autoimmune diseases
    • Louzoun Y., Atlan H., Cohen I.R. Modeling the influence of TH1-and TH2-type cells in autoimmune diseases. J. Autoimmun. 2001, 17(4):311-321.
    • (2001) J. Autoimmun. , vol.17 , Issue.4 , pp. 311-321
    • Louzoun, Y.1    Atlan, H.2    Cohen, I.R.3
  • 35
    • 33745666983 scopus 로고    scopus 로고
    • Ultra-rush venom immunotherapy induces differential T cell activation and regulatory patterns according to the severity of allergy
    • Mamessier E., Birnbaum J., Dupuy P., Vervloet D., Magnan A. Ultra-rush venom immunotherapy induces differential T cell activation and regulatory patterns according to the severity of allergy. Clin. Exp. Allergy 2006, 36(6):704-713.
    • (2006) Clin. Exp. Allergy , vol.36 , Issue.6 , pp. 704-713
    • Mamessier, E.1    Birnbaum, J.2    Dupuy, P.3    Vervloet, D.4    Magnan, A.5
  • 36
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann T.R., Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol. Today 1996, 17(3):138-146.
    • (1996) Immunol. Today , vol.17 , Issue.3 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 39
    • 1542376710 scopus 로고    scopus 로고
    • Mosquito allergy: immune mechanisms and recombinant salivary allergens
    • Peng Z., Simons F.E.R. Mosquito allergy: immune mechanisms and recombinant salivary allergens. Int. Arch. Allergy Immunol. 2004, 133(2):198-209.
    • (2004) Int. Arch. Allergy Immunol. , vol.133 , Issue.2 , pp. 198-209
    • Peng, Z.1    Simons, F.E.R.2
  • 40
    • 0036325921 scopus 로고    scopus 로고
    • Mathematical modelling of venom immunotherapy
    • Richter J., Metzner G., Behn U. Mathematical modelling of venom immunotherapy. J. Theor. Med. 2002, 4(2):119-132.
    • (2002) J. Theor. Med. , vol.4 , Issue.2 , pp. 119-132
    • Richter, J.1    Metzner, G.2    Behn, U.3
  • 41
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • Romagnani S. The Th1/Th2 paradigm. Immunol. Today 1997, 18(6):263-266.
    • (1997) Immunol. Today , vol.18 , Issue.6 , pp. 263-266
    • Romagnani, S.1
  • 42
    • 0033949795 scopus 로고    scopus 로고
    • The antigen dose determines T helper subset development by regulation of CD40 ligand
    • Ruedl C., Bachmann M.F., Kopf M. The antigen dose determines T helper subset development by regulation of CD40 ligand. Eur. J. Immunol. 2000, 30(7):2056-2064.
    • (2000) Eur. J. Immunol. , vol.30 , Issue.7 , pp. 2056-2064
    • Ruedl, C.1    Bachmann, M.F.2    Kopf, M.3
  • 44
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells key controllers of immunologic self-tolerance
    • Sakaguchi S. Regulatory T cells key controllers of immunologic self-tolerance. Cell 2000, 101(5):455-458.
    • (2000) Cell , vol.101 , Issue.5 , pp. 455-458
    • Sakaguchi, S.1
  • 45
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+ CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+ CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 2005, 6(4):345-352.
    • (2005) Nat. Immunol. , vol.6 , Issue.4 , pp. 345-352
    • Sakaguchi, S.1
  • 47
    • 0028931038 scopus 로고
    • Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type
    • Secrist H., DeKruyff R., Umetsu D. Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type. J. Exp. Med. 1995, 181(3):1081-1089.
    • (1995) J. Exp. Med. , vol.181 , Issue.3 , pp. 1081-1089
    • Secrist, H.1    DeKruyff, R.2    Umetsu, D.3
  • 48
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of foxp3+ T regulatory cell-mediated suppression
    • Shevach E.M. Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 2009, 30(5):636-645.
    • (2009) Immunity , vol.30 , Issue.5 , pp. 636-645
    • Shevach, E.M.1
  • 49
    • 33645023639 scopus 로고    scopus 로고
    • Mechanisms of immune suppression by interleukin-10 and transforming growth factor-Β: the role of T regulatory cells
    • Taylor A., Verhagen J., Blaser K., Akdis M., Akdis C.A. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-Β: the role of T regulatory cells. Immunology 2006, 117(4):433-442.
    • (2006) Immunology , vol.117 , Issue.4 , pp. 433-442
    • Taylor, A.1    Verhagen, J.2    Blaser, K.3    Akdis, M.4    Akdis, C.A.5
  • 50
    • 52949116490 scopus 로고    scopus 로고
    • From the two-dimensional Th1 and Th2 phenotypes to high-dimensional models for gene regulation
    • Van Den Ham H., De Boer R. From the two-dimensional Th1 and Th2 phenotypes to high-dimensional models for gene regulation. Int. Immunol. 2008, 20(10):1269-1277.
    • (2008) Int. Immunol. , vol.20 , Issue.10 , pp. 1269-1277
    • Van Den Ham, H.1    De Boer, R.2
  • 51
    • 78650284721 scopus 로고    scopus 로고
    • Th1-Th2 regulation and allergy: bifurcation analysis of the non-autonomous system
    • Birkhäuser, Boston, A. Deutsch (Ed.)
    • Vogel R., Behn U. Th1-Th2 regulation and allergy: bifurcation analysis of the non-autonomous system. Mathematical Modeling of Biological Systems 2007, 155-157. Birkhäuser, Boston. A. Deutsch (Ed.).
    • (2007) Mathematical Modeling of Biological Systems , pp. 155-157
    • Vogel, R.1    Behn, U.2
  • 52
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G., Wei L., Zhu J., Zang C., Hu-Li J., Yao Z., Cui K., Kanno Y., Roh T.Y., Watford W.T., et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009, 30(1):155-167.
    • (2009) Immunity , vol.30 , Issue.1 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3    Zang, C.4    Hu-Li, J.5    Yao, Z.6    Cui, K.7    Kanno, Y.8    Roh, T.Y.9    Watford, W.T.10
  • 53
    • 0035495857 scopus 로고    scopus 로고
    • The germless theory of allergic disease: revisiting the hygiene hypothesis
    • Wills-Karp M., Santeliz J., Karp C.L. The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat. Rev. Immunol. 2001, 1(1):69-75.
    • (2001) Nat. Rev. Immunol. , vol.1 , Issue.1 , pp. 69-75
    • Wills-Karp, M.1    Santeliz, J.2    Karp, C.L.3
  • 55
    • 0037134046 scopus 로고    scopus 로고
    • Allergy, parasites, and the hygiene hypothesis
    • Yazdanbakhsh M., Kremsner P.G., van Ree R. Allergy, parasites, and the hygiene hypothesis. Science 2002, 296(5567):490-494.
    • (2002) Science , vol.296 , Issue.5567 , pp. 490-494
    • Yazdanbakhsh, M.1    Kremsner, P.G.2    van Ree, R.3
  • 56
    • 73849110167 scopus 로고    scopus 로고
    • Heterogeneity plasticity of T helper cells
    • Zhu J., Paul W.E. Heterogeneity plasticity of T helper cells. Cell Res. 2009, 20:4-12.
    • (2009) Cell Res. , vol.20 , pp. 4-12
    • Zhu, J.1    Paul, W.E.2


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