-
1
-
-
0036154959
-
Quantitative analyses of SMN1 and SMN2 based on real-time lightcycler PCR: Fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy
-
Feldkotter M, Schwarzer V, Wirth R, et al. Quantitative analyses of SMN1 and SMN2 based on real-time lightcycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy. Am J Hum Genet 2002;70(2):10
-
(2002)
Am J Hum Genet
, vol.70
, Issue.2
, pp. 10
-
-
Feldkotter, M.1
Schwarzer, V.2
Wirth, R.3
-
2
-
-
74249094999
-
Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy
-
Baumer D, Lee S, Nicholson G, et al. Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy. PLoS Genet 2009;5(12):e1000773
-
(2009)
PLoS Genet
, vol.5
, Issue.12
-
-
Baumer, D.1
Lee, S.2
Nicholson, G.3
-
3
-
-
0028797783
-
Identification and characterization of a spinal muscular atrophy-determining gene
-
Lefebvre S, Burglen L, Reboullet S, et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell 1995;80(1):10
-
(1995)
Cell
, vol.80
, Issue.1
, pp. 10
-
-
Lefebvre, S.1
Burglen, L.2
Reboullet, S.3
-
4
-
-
77953893282
-
Spinal muscular atrophy: Mechanisms and therapeutic strategies
-
Lorson CL, Rindt H, Shababi M. Spinal muscular atrophy: mechanisms and therapeutic strategies. Hum Mol Genet 2010;19(R1):R111-18
-
(2010)
Hum Mol Genet
, vol.19
, Issue.R1
-
-
Lorson, C.L.1
Rindt, H.2
Shababi, M.3
-
5
-
-
48249145306
-
Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
-
Kariya S, Park G-H, Maeno-Hikichi Y, et al. Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy. Hum Mol Genet 2008;17(16):2552-2569
-
(2008)
Hum Mol Genet
, vol.17
, Issue.16
, pp. 2552-2569
-
-
Kariya, S.1
Park, G.-H.2
Maeno-Hikichi, Y.3
-
6
-
-
37749054939
-
Induction of full-length survival motor neuron by polyphenol botanical compounds
-
Sakla M, Lorson C. Induction of full-length survival motor neuron by polyphenol botanical compounds. Hum Genet 2008;122(6):635-643
-
(2008)
Hum Genet
, vol.122
, Issue.6
, pp. 635-643
-
-
Sakla, M.1
Lorson, C.2
-
8
-
-
0345332575
-
Maturation of the acetylcholine receptor in skeletal muscle: Regulation of the AChR [gamma]-to-[epsilon] switch
-
Missias AC, Chu GC, Klocke BJ, et al. Maturation of the acetylcholine receptor in skeletal muscle: regulation of the AChR [gamma]-to-[epsilon] switch. Dev Biol 1996;179(1):223-238
-
(1996)
Dev Biol
, vol.179
, Issue.1
, pp. 223-238
-
-
Missias, A.C.1
Chu, G.C.2
Klocke, B.J.3
-
9
-
-
0029125140
-
Local neurotrophic repression of gene transcripts encoding fetal AChRs at rat neuromuscular synapses
-
Kues WA, Brenner HR, Sakmann B, Witzemann V. Local neurotrophic repression of gene transcripts encoding fetal AChRs at rat neuromuscular synapses. J Cell Biol 1995;130(4):8
-
(1995)
J Cell Biol
, vol.130
, Issue.4
, pp. 8
-
-
Kues, W.A.1
Brenner, H.R.2
Sakmann, B.3
Witzemann, V.4
-
10
-
-
77955602960
-
Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord
-
Rossi SL, Nistor G, Wyatt T, et al. Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord. PLoS ONE 2010;5(7):e11852
-
(2010)
PLoS ONE
, vol.5
, Issue.7
-
-
Rossi, S.L.1
Nistor, G.2
Wyatt, T.3
-
11
-
-
77950462859
-
To build a synapse: Signaling pathways in neuromuscular junction assembly
-
Wu H, Xiong WC, Mei L. To build a synapse: signaling pathways in neuromuscular junction assembly. Development 2010;137:1017-1033
-
(2010)
Development
, vol.137
, pp. 1017-1033
-
-
Wu, H.1
Xiong, W.C.2
Mei, L.3
-
12
-
-
33748935769
-
Development of the neuromuscular junction
-
Witzemann V. Development of the neuromuscular junction. Cell Tissue Res 2006;326(2):8
-
(2006)
Cell Tissue Res
, vol.326
, Issue.2
, pp. 8
-
-
Witzemann, V.1
-
13
-
-
18844365359
-
The acetylcholine receptor [gamma]-to-[epsilon] switch occurs in individual endplates
-
Yumoto N, Wakatsuki S, Sehara-Fujisawa A. The acetylcholine receptor [gamma]-to-[epsilon] switch occurs in individual endplates. Biochem Biophys Res Commun 2005;331(4):1522-1527
-
(2005)
Biochem Biophys Res Commun
, vol.331
, Issue.4
, pp. 1522-1527
-
-
Yumoto, N.1
Wakatsuki, S.2
Sehara-Fujisawa, A.3
-
14
-
-
49849100786
-
Implantation of human umbilical cord-derived mesenchymal stem cells as a neuroprotective therapy for ischemic stroke in rats
-
Koh S, Kim KS, Choi MR, et al. Implantation of human umbilical cord-derived mesenchymal stem cells as a neuroprotective therapy for ischemic stroke in rats. Brain Res 2008;1229:233-248
-
(2008)
Brain Res
, vol.1229
, pp. 233-248
-
-
Koh, S.1
Kim, K.S.2
Choi, M.R.3
-
15
-
-
0035899304
-
Asynchronous synapse elimination in neonatal motor units: Studies using GFP transgenic mice
-
Keller-Peck CR, Walsh MK, Gan WB, et al. Asynchronous synapse elimination in neonatal motor units: studies using GFP transgenic mice. Neuron 2001;31:13
-
(2001)
Neuron
, vol.31
, pp. 13
-
-
Keller-Peck, C.R.1
Walsh, M.K.2
Gan, W.B.3
-
16
-
-
0027462315
-
In vivo obsevations of pre- and postsynaptic changes during the transition from multiple to single innervation at developing neuromuscular junctions
-
Balice-Gordon RJ, Lichtman JW. In vivo obsevations of pre- and postsynaptic changes during the transition from multiple to single innervation at developing neuromuscular junctions. J Neurosci 1993;13:21
-
(1993)
J Neurosci
, vol.13
, pp. 21
-
-
Balice-Gordon, R.J.1
Lichtman, J.W.2
-
17
-
-
77958516191
-
Reduced expression of nicotinic AChRs in myotubes from spinal muscular atrophy i patients
-
Arnold A, Gueye M, Guettier-Sigrist S, et al. Reduced expression of nicotinic AChRs in myotubes from spinal muscular atrophy I patients. Nature 2004;84(10):7
-
(2004)
Nature
, vol.84
, Issue.10
, pp. 7
-
-
Arnold, A.1
Gueye, M.2
Guettier-Sigrist, S.3
-
18
-
-
41149113045
-
Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy
-
Murray LM, Comley LH, Thomson D, et al. Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy. Hum Mol Genet 2008;17(7):949-962
-
(2008)
Hum Mol Genet
, vol.17
, Issue.7
, pp. 949-962
-
-
Murray, L.M.1
Comley, L.H.2
Thomson, D.3
-
19
-
-
29144463310
-
Spinal muscular atrophy: A deficiency in a ubiquitous protein; A motor neuron-specific disease
-
Monani UR. Spinal muscular atrophy: a deficiency in a ubiquitous protein; a motor neuron-specific disease. Neuron 2005;48(6):885-895
-
(2005)
Neuron
, vol.48
, Issue.6
, pp. 885-895
-
-
Monani, U.R.1
-
20
-
-
0029661887
-
Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice
-
Witzemann V, Schwarz H, Koenen M, et al. Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice. Proc Natl Acad Sci USA 1996;93:5
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5
-
-
Witzemann, V.1
Schwarz, H.2
Koenen, M.3
-
21
-
-
67651083390
-
Spinal muscular atrophy: Why do low levels of survival motor neuron protein make motor neurons sick?
-
Burghes AHBC. Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick? Nat Rev Neurosci 2009;10(8):12
-
(2009)
Nat Rev Neurosci
, vol.10
, Issue.8
, pp. 12
-
-
Burghes, A.H.B.C.1
-
22
-
-
77249088647
-
Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice
-
Corti S, Nizzardo M, Nardini M, et al. Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice. Brain 2010;133(2):465-481
-
(2010)
Brain
, vol.133
, Issue.2
, pp. 465-481
-
-
Corti, S.1
Nizzardo, M.2
Nardini, M.3
-
23
-
-
69149108013
-
Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS
-
Karumbayaram S, Kelly TK, Paucar AA, et al. Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS. Dis Model Mechanobiol 2009;2:6
-
(2009)
Dis Model Mechanobiol
, vol.2
, pp. 6
-
-
Karumbayaram, S.1
Kelly, T.K.2
Paucar, A.A.3
-
24
-
-
69249202573
-
Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells
-
Wada T, Honda M, Minami I, et al. Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells. PLoS One 2009;4(8):e6722
-
(2009)
PLoS One
, vol.4
, Issue.8
-
-
Wada, T.1
Honda, M.2
Minami, I.3
-
25
-
-
13844271605
-
Specification of motoneurons from human embryonic stem cells
-
Li XJ, Du ZW, Zarnowska ED, et al. Specification of motoneurons from human embryonic stem cells. Nat Biotechnol 2005;23:6
-
(2005)
Nat Biotechnol
, vol.23
, pp. 6
-
-
Li, X.J.1
Du, Z.W.2
Zarnowska, E.D.3
-
26
-
-
27744438009
-
Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells
-
Roy NS, Nakano T, Xuing L, et al. Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells. Exp Neurol 2005;196:10
-
(2005)
Exp Neurol
, vol.196
, pp. 10
-
-
Roy, N.S.1
Nakano, T.2
Xuing, L.3
-
27
-
-
74949087489
-
Stem cells in human neurodegenerative disorders, Ai time for clinical translation?
-
Lindvall O, Kokaia Z. Stem cells in human neurodegenerative disorders, Ai time for clinical translation? J Clin Invest 2010;120(1):29-40
-
(2010)
J Clin Invest
, vol.120
, Issue.1
, pp. 29-40
-
-
Lindvall, O.1
Kokaia, Z.2
-
28
-
-
61449171881
-
Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient
-
Amariglio NHA, Scheithauer BW, Cohen Y, et al. Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. PLoS Med 2009;6(2):e1000029
-
(2009)
PLoS Med
, vol.6
, Issue.2
-
-
Amariglio, N.H.A.1
Scheithauer, B.W.2
Cohen, Y.3
-
29
-
-
18644384444
-
Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury
-
Keirstead HS, Nistor G, Bernal G, et al. Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury. J Neurosci 2005;25(19):4694-4705
-
(2005)
J Neurosci
, vol.25
, Issue.19
, pp. 4694-4705
-
-
Keirstead, H.S.1
Nistor, G.2
Bernal, G.3
-
30
-
-
33745686121
-
Recovery from paralysis in adult rats using embryonic stem cells
-
Deshpande DMKY, Martinez T, Carmen J, et al. Recovery from paralysis in adult rats using embryonic stem cells. Ann Neurol 2006;60(1):12
-
(2006)
Ann Neurol
, vol.60
, Issue.1
, pp. 12
-
-
Deshpande, D.M.K.Y.1
Martinez, T.2
Carmen, J.3
-
31
-
-
0037183512
-
Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery
-
Li Y, Chen J, Chen XG, et al. Human marrow stromal cell therapy for stroke in rat: neurotrophins and functional recovery. Neurology 2002;59(4):514-523
-
(2002)
Neurology
, vol.59
, Issue.4
, pp. 514-523
-
-
Li, Y.1
Chen, J.2
Chen, X.G.3
-
32
-
-
33745601099
-
Stem cells for the treatment of neurological disorders
-
Lindvall O, Kokaia Z. Stem cells for the treatment of neurological disorders. Nature 2006;441(7097):1094-1096
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1094-1096
-
-
Lindvall, O.1
Kokaia, Z.2
-
33
-
-
37849022487
-
Stem cell treatment in amyotrophic lateral sclerosis
-
Mazzini L, Mareschi K, Ferrero I, et al. Stem cell treatment in amyotrophic lateral sclerosis. J Neurol Sci 2008;265(1-2):78-83
-
(2008)
J Neurol Sci
, vol.265
, Issue.1-2
, pp. 78-83
-
-
Mazzini, L.1
Mareschi, K.2
Ferrero, I.3
-
34
-
-
0038054469
-
Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury
-
Lu P, Jones LL, Snyder EY, Tuszynski MH. Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol 2002;181:14
-
(2002)
Exp Neurol
, vol.181
, pp. 14
-
-
Lu, P.1
Jones, L.L.2
Snyder, E.Y.3
Tuszynski, M.H.4
-
36
-
-
32644451922
-
Neurotrophin signalling in health and disease
-
Chao MV, Rajagopal R, Lee FS. Neurotrophin signalling in health and disease. Clin Sci 2006;110:6
-
(2006)
Clin Sci
, vol.110
, pp. 6
-
-
Chao, M.V.1
Rajagopal, R.2
Lee, F.S.3
-
38
-
-
58849103600
-
Impaired synaptic vesicle release and immaturity of neuromuscular junctions in spinal muscular atrophy mice
-
Kong L, Wang X, Choe DW, et al. Impaired synaptic vesicle release and immaturity of neuromuscular junctions in spinal muscular atrophy mice. J Neuroscience 2009;29(3):9
-
(2009)
J Neuroscience
, vol.29
, Issue.3
, pp. 9
-
-
Kong, L.1
Wang, X.2
Choe, D.W.3
-
39
-
-
36448939830
-
Synaptic dysfunction in disease and following injury in the developing and adult nervous system: Caveats in the choice of therapeutic intervention
-
Gould TW, Oppenheim RW. Synaptic dysfunction in disease and following injury in the developing and adult nervous system: caveats in the choice of therapeutic intervention. Neurosci Biobehav Rev 2007;31(8):1073-1087
-
(2007)
Neurosci Biobehav Rev
, vol.31
, Issue.8
, pp. 1073-1087
-
-
Gould, T.W.1
Oppenheim, R.W.2
-
40
-
-
0027281189
-
Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF
-
Lohof AM, Ip NY, Poo M-M. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature 1993;363(6427):350-353
-
(1993)
Nature
, vol.363
, Issue.6427
, pp. 350-353
-
-
Lohof, A.M.1
Ip, N.Y.2
Poo, M.-M.3
-
41
-
-
14744272637
-
Neurotrophin-mediated rapid signaling in the central nervous system: Mechanisms and functions
-
Blum R, Konnerth A. Neurotrophin-mediated rapid signaling in the central nervous system: mechanisms and functions. Physiology 2005;20(1):70-78
-
(2005)
Physiology
, vol.20
, Issue.1
, pp. 70-78
-
-
Blum, R.1
Konnerth, A.2
-
42
-
-
77958488761
-
Arabidopsis thaliana, a plant model organism for the neuronal microtubule cytoskeleton?
-
[Epub ahead of print, doi 10.1093/jxb/erq278]
-
Gardiner J, Marc J. Arabidopsis thaliana, a plant model organism for the neuronal microtubule cytoskeleton? J Exp Bot 2010. [Epub ahead of print, doi: 10.1093/jxb/erq278]
-
(2010)
J Exp Bot
-
-
Gardiner, J.1
Marc, J.2
-
43
-
-
0347694856
-
Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase
-
Gao Y, Nikulina E, Mellado W, Filbin MT. Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase. J Neurosci 2003;23(37):7
-
(2003)
J Neurosci
, vol.23
, Issue.37
, pp. 7
-
-
Gao, Y.1
Nikulina, E.2
Mellado, W.3
Filbin, M.T.4
-
44
-
-
2342472526
-
Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats
-
Harper JMKC, Darman JS, Deshpande DM, et al. Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats. Proc Natl Acad Sci USA 2004;101(18):5
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.18
, pp. 5
-
-
Harper, J.M.K.C.1
Darman, J.S.2
Deshpande, D.M.3
-
45
-
-
1542754063
-
MT. A role for cAMP in regeneration of the adult mammalian CNS
-
Spencer TAF, MT. A role for cAMP in regeneration of the adult mammalian CNS. J Anat 2004;204:5
-
(2004)
J Anat
, vol.204
, pp. 5
-
-
Spencer, T.A.F.1
-
46
-
-
26244434407
-
Is spinal muscular atrophy the result of defects in motor neuron processes?
-
Briese M, Esmaeili B, Sattelle DB. Is spinal muscular atrophy the result of defects in motor neuron processes? BioEssays 2005;27(9):946-957
-
(2005)
BioEssays
, vol.27
, Issue.9
, pp. 946-957
-
-
Briese, M.1
Esmaeili, B.2
Sattelle, D.B.3
-
47
-
-
0029020311
-
Neurotrophins promote maturation of developing neuromuscular synapses
-
Wang T, Xie K, Lu B. Neurotrophins promote maturation of developing neuromuscular synapses. J Neurosci 1995;15(7):4796-4805
-
(1995)
J Neurosci
, vol.15
, Issue.7
, pp. 4796-4805
-
-
Wang, T.1
Xie, K.2
Lu, B.3
-
48
-
-
3042622278
-
Neurotrophic regulation of the development and function of the neuromuscular synapses
-
Lu B, Je HS. Neurotrophic regulation of the development and function of the neuromuscular synapses. J Neurocytol 2003;32:931-941
-
(2003)
J Neurocytol
, vol.32
, pp. 931-941
-
-
Lu, B.1
Je, H.S.2
-
49
-
-
68249134222
-
Neurotrophic factors improve motoneuron survival and function of muscle reinnervated by embryonic neurons
-
Grumbles RM, Sesodia S, Wood PM, Thomas CK. Neurotrophic factors improve motoneuron survival and function of muscle reinnervated by embryonic neurons. J Neuropathol Exp Neurol 2009;68(7):736-746
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, Issue.7
, pp. 736-746
-
-
Grumbles, R.M.1
Sesodia, S.2
Wood, P.M.3
Thomas, C.K.4
-
50
-
-
0033118385
-
Expression of neurotrophins in the adult spinal cord in vivo
-
Dreyfus CF, Dai X, Lercher LD, et al. Expression of neurotrophins in the adult spinal cord in vivo. J Neurosci Res 1999;56:7
-
(1999)
J Neurosci Res
, vol.56
, pp. 7
-
-
Dreyfus, C.F.1
Dai, X.2
Lercher, L.D.3
-
51
-
-
16644391766
-
CNS neurotrophins are biologically active and expressed by multiple cell types
-
Riley CP, Cope TC, Buck CR. CNS neurotrophins are biologically active and expressed by multiple cell types. J Mol Histol 2004;35(8-9):771-783
-
(2004)
J Mol Histol
, vol.35
, Issue.8-9
, pp. 771-783
-
-
Riley, C.P.1
Cope, T.C.2
Buck, C.R.3
-
52
-
-
41249086987
-
Combining growth factor and stem cell therapy for amyotrophic lateral sclerosis
-
Suzuki M, Svendsen CN. Combining growth factor and stem cell therapy for amyotrophic lateral sclerosis. Trends Neurosci 2008;31(4):6
-
(2008)
Trends Neurosci
, vol.31
, Issue.4
, pp. 6
-
-
Suzuki, M.1
Svendsen, C.N.2
-
53
-
-
0023257693
-
Control of end-plate channel properties by neurotrophic effects and by muscle activity in rats
-
Brenner HR, Lomo T, Williamson R. Control of end-plate channel properties by neurotrophic effects and by muscle activity in rats. J Physiol 1987;388:367-381
-
(1987)
J Physiol
, vol.388
, pp. 367-381
-
-
Brenner, H.R.1
Lomo, T.2
Williamson, R.3
-
54
-
-
0025783907
-
Functional adult acetylcholine receptor develops independently of motor innervation in Sol 8 mouse muscle cell line
-
Pinset C, Mulle C, Benoit P, et al. Functional adult acetylcholine receptor develops independently of motor innervation in Sol 8 mouse muscle cell line. EMBO J 1991;10(9):7
-
(1991)
EMBO J
, vol.10
, Issue.9
, pp. 7
-
-
Pinset, C.1
Mulle, C.2
Benoit, P.3
-
55
-
-
77949889554
-
Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy
-
Murray LMLS, Baumer D, Parson SH, et al. Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy. Hum Mol Genet 2010;19(3):13
-
(2010)
Hum Mol Genet
, vol.19
, Issue.3
, pp. 13
-
-
Murray, L.M.L.S.1
Baumer, D.2
Parson, S.H.3
-
56
-
-
0027180752
-
Possible consequences of disruption of neuromuscular contacts in early development for motoneurone survival
-
Greensmith L, Sieradzan K, Vrbova G. Possible consequences of disruption of neuromuscular contacts in early development for motoneurone survival. Acta Neurobiol Exp (Wars) 1993;53:319-324
-
(1993)
Acta Neurobiol Exp (Wars)
, vol.53
, pp. 319-324
-
-
Greensmith, L.1
Sieradzan, K.2
Vrbova, G.3
-
57
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert AD, Yu J, Rose FF, et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009;457(7227):277-280
-
(2009)
Nature
, vol.457
, Issue.7227
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, F.F.3
-
58
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park I-H, Zhao R, West JA, et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008;451(7175):141-146
-
(2008)
Nature
, vol.451
, Issue.7175
, pp. 141-146
-
-
Park, I.-H.1
Zhao, R.2
West, J.A.3
-
59
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
Jaenisch R, Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 2008;132(4):567-582
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
60
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131(5):861-872
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
61
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007;318(5858):1917-1920
-
(2007)
Science
, vol.318
, Issue.5858
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
62
-
-
77954113167
-
Therapy development in spinal muscular atrophy
-
Sendtner M. Therapy development in spinal muscular atrophy. Nat Neurosci 2010;13(7):795-799
-
(2010)
Nat Neurosci
, vol.13
, Issue.7
, pp. 795-799
-
-
Sendtner, M.1
-
63
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008;321(5893):1218-1221
-
(2008)
Science
, vol.321
, Issue.5893
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
-
64
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
Park I-H, Arora N, Huo H, et al. Disease-specific induced pluripotent stem cells. Cell 2008;134(5):877-886
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 877-886
-
-
Park, I.-H.1
Arora, N.2
Huo, H.3
-
65
-
-
72849144528
-
Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells
-
Pick M, Stelzer Y, Bar-Nur O, et al. Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells. Stem Cells 2009;27(11):2686-2690
-
(2009)
Stem Cells
, vol.27
, Issue.11
, pp. 2686-2690
-
-
Pick, M.1
Stelzer, Y.2
Bar-Nur, O.3
-
66
-
-
77953879152
-
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseses
-
Marchetto MCN, Winner B, Gage FH. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseses. Hum Mol Genet 2010;19(R1):5
-
(2010)
Hum Mol Genet
, vol.19
, Issue.R1
, pp. 5
-
-
Marchetto, M.C.N.1
Winner, B.2
Gage, F.H.3
-
67
-
-
77953623111
-
Stem cell model of spinal muscular atrophy
-
Ebert AD, Svendsen CN. Stem cell model of spinal muscular atrophy. Arch Neurol 2010;67(6):665-669
-
(2010)
Arch Neurol
, vol.67
, Issue.6
, pp. 665-669
-
-
Ebert, A.D.1
Svendsen, C.N.2
-
68
-
-
77949909934
-
Review: Neuromuscular synaptic vulnerability in motor neurone disease: Amyotrophic lateral sclerosis and spinal muscular atrophy
-
Murray LM, Talbot K, Gillingwater TH. Review: neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy. Neuropathol Appl Neurobiol 2010;36(2):133-156
-
(2010)
Neuropathol Appl Neurobiol
, vol.36
, Issue.2
, pp. 133-156
-
-
Murray, L.M.1
Talbot, K.2
Gillingwater, T.H.3
-
69
-
-
34548157546
-
Animal models of spinal muscular atrophy
-
DiDonato CJ, Schmid A. Animal models of spinal muscular atrophy. J Child Neurol 2007;22:8
-
(2007)
J Child Neurol
, vol.22
, pp. 8
-
-
Didonato, C.J.1
Schmid, A.2
-
70
-
-
77958497676
-
Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy
-
Butchbach ME, Singh J, Thorsteinsdottir M, et al. Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy. Hum Mol Genet 2010;14:15
-
Hum Mol Genet
, vol.2010
, Issue.14
, pp. 15
-
-
Butchbach, M.E.1
Singh, J.2
Thorsteinsdottir, M.3
-
71
-
-
33847358736
-
Trichostatin A incrases SMN expression and survival in a mouse model of spinal muscular atrophy
-
Avila AM, Burnett BG, Taye AA, et al. Trichostatin A incrases SMN expression and survival in a mouse model of spinal muscular atrophy. J Clin Invest 2007;117:12
-
(2007)
J Clin Invest
, vol.117
, pp. 12
-
-
Avila, A.M.1
Burnett, B.G.2
Taye, A.A.3
-
72
-
-
77952295831
-
SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy
-
Riessland M, Ackermann B, Forster B, et al. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy. Hum Mol Genet 2010;19:14
-
Hum Mol Genet
, vol.2010
, Issue.19
, pp. 14
-
-
Riessland, M.1
Ackermann, B.2
Forster, B.3
-
73
-
-
70350749543
-
LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate
-
Garbes L, Riessland M, Holker I, et al. LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate. Hum Mol Genet 2009;18:13
-
(2009)
Hum Mol Genet
, vol.18
, pp. 13
-
-
Garbes, L.1
Riessland, M.2
Holker, I.3
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