A new fluorogenic peptide determines proteasome activity in single cells

Journal of Medicinal Chemistry

Volumn 53, Issue 20, 2010, Pages 7452-7460

  Urru, Silvana A M ^a   Veglianese, Pietro ^a   De Luigi, Ada ^a   Fumagalli, Elena ^a   Erba, Eugenio ^a   Gonella Diaza, Rodolfo ^a   Carrà, Andrea ^a   Davoli, Enrico ^a   Borsello, Tiziana ^a   Forloni, Gianluigi ^a   Pengo, Niccolò ^b   Monzani, Enrico ^c   Cascio, Paolo ^d   Cenci, Simone ^b   Sitia, Roberto ^b   Salmona, Mario ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BORTEZOMIB; CHYMOTRYPSIN; EPOXOMICIN; FLUORESCENT DYE; PEPTIDE DERIVATIVE; PROTEASOME; PROTEASOME INHIBITOR; PEPTIDE; PROTEIN SUBUNIT; TAT-EDANS-DABCYL PEPTIDE;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; DRUG POTENCY; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SPECIFICITY; FLOW CYTOMETRY; FLUORESCENCE; FLUORESCENCE ANALYSIS; HELA CELL; HUMAN; HUMAN CELL; MOUSE; MULTIPLE MYELOMA; NONHUMAN; PROTEIN ENGINEERING; PROTEIN MOTIF; UTERINE CERVIX CARCINOMA; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; HIPPOCAMPUS; METABOLISM; NERVE CELL; PROTEIN SUBUNIT; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; FLOW CYTOMETRY; FLUORESCENT DYES; HIPPOCAMPUS; HUMANS; MICE; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; NEURONS; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS;

EID: 77958464352     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100362x     Document Type: Article

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