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Volumn 535, Issue , 2009, Pages 165-186

Locked nucleic acid aptamers

Author keywords

LNA Ag LNA antigene; LNA Ap LNA aptamer; LNA As LNA antisense; LNA locked nucleic acid

Indexed keywords

APTAMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOCKED NUCLEIC ACID; OLIGONUCLEOTIDE; ORGANOPHOSPHORUS COMPOUND; PHOSPHORAMIDOUS ACID; TENASCIN; THROMBIN;

EID: 77958154053     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-557-2_10     Document Type: Article
Times cited : (23)

References (27)
  • 2
    • 6344277190 scopus 로고    scopus 로고
    • LNA (Locked Nucleic Acid): High-affinity targeting of complementary RNA and DNA
    • Vester, B. and Wengel, J. (2004) LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA. Biochemistry 43, 13233-13241. (Pubitemid 39391124)
    • (2004) Biochemistry , vol.43 , Issue.42 , pp. 13233-13241
    • Vester, B.1    Wengel, J.2
  • 3
    • 0035113736 scopus 로고    scopus 로고
    • Locked nucleic acid (LNA): Fine-tuning the recognition of DNA and RNA
    • DOI 10.1016/S1074-5521(00)00058-2, PII S1074552100000582
    • Braasch, D.A. and Corey, D.R. (2001) Locked nucleic acid (LNA): fine-tuning the recognition of DNA and RNA. Chem. Biol. 8, 1-7. (Pubitemid 32165807)
    • (2001) Chemistry and Biology , vol.8 , Issue.1 , pp. 1-7
    • Braasch, D.A.1    Corey, D.R.2
  • 4
    • 34250679056 scopus 로고    scopus 로고
    • Locked nucleic acid oligonucleotides: The next generation of antisense agents?
    • DOI 10.2165/00063030-200721040-00004
    • Grunweller, A. and Hartmann, R.K. (2007) Locked nucleic Acid oligonucleotides: the next generation of antisense agents? Bio-Drugs 21, 235-243. (Pubitemid 47104979)
    • (2007) BioDrugs , vol.21 , Issue.4 , pp. 235-243
    • Grunweller, A.1    Hartmann, R.K.2
  • 5
    • 36849035783 scopus 로고    scopus 로고
    • Perspective on chemistry and therapeutic applications of locked nucleic acid (LNA)
    • DOI 10.1021/cr050266u
    • Kaur, H., Babu, B.R. and Maiti, S. (2007) Perspectives on chemistry and therapeutic applications of Locked Nucleic Acid (LNA). Chem. Rev. 107, 4672-4697. (Pubitemid 350225863)
    • (2007) Chemical Reviews , vol.107 , Issue.11 , pp. 4672-4697
    • Kaur, H.1    Babu, B.R.2    Maiti, S.3
  • 6
    • 0037310844 scopus 로고    scopus 로고
    • LNA: A versatile tool for therapeutics and genomics
    • DOI 10.1016/S0167-7799(02)00038-0
    • Petersen, M. and Wengel, J. (2003) LNA: a versatile tool for therapeutics and genomics. Trends Biotechnol. 21, 74-81. (Pubitemid 36165007)
    • (2003) Trends in Biotechnology , vol.21 , Issue.2 , pp. 74-81
    • Petersen, M.1    Wengel, J.2
  • 7
    • 0036567147 scopus 로고    scopus 로고
    • Design of antisense oligonucleotides stabilized by locked nucleic acids
    • Kurreck, J., Wyszko, E., Gillen, C. and Erd-mann, V.A. (2002) Design of antisense oli-gonucleotides stabilized by locked nucleic acids. Nucleic Acids Res. 30, 1911-1918. (Pubitemid 34537585)
    • (2002) Nucleic Acids Research , vol.30 , Issue.9 , pp. 1911-1918
    • Kurreck, J.1    Wyszko, E.2    Gillen, C.3    Erdmann, V.A.4
  • 8
    • 35148869236 scopus 로고    scopus 로고
    • The structure of LNA:DNA hybrids from molecular dynamics simulations: The effect of locked nucleotides
    • DOI 10.1021/jp073198j
    • Ivanova, A. and Rosch, N. (2007) The structure of LNA:DNA hybrids from molecular dynamics simulations: the effect of locked nucleotides. J. Phys. Chem. 111, 9307-9319. (Pubitemid 47548319)
    • (2007) Journal of Physical Chemistry A , vol.111 , Issue.38 , pp. 9307-9319
    • Ivanova, A.1    Rosch, N.2
  • 9
    • 10044269637 scopus 로고    scopus 로고
    • Locked nucleic acids (LNA): Versatile tools for designing oligonucleotide decoys with high stability and affinity
    • DOI 10.2174/1389450043345083
    • Crinelli, R., Bianchi, M., Gentilini, L., Palma, L. and Magnani, M. (2004) Locked nucleic acids (LNA): versatile tools for designing oligonucleotide decoys with high stability and affinity. Curr. Drug Targets 5, 745-752. (Pubitemid 39600012)
    • (2004) Current Drug Targets , vol.5 , Issue.8 , pp. 745-752
    • Crinelli, R.1    Bianchi, M.2    Gentilini, L.3    Palma, L.4    Magnani, M.5
  • 10
    • 35148840942 scopus 로고    scopus 로고
    • Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy
    • DOI 10.1021/cr0306743
    • Famulok, M., Hartig, J.S. and Mayer, G. (2007) Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy. Chem. Rev. 107, 3715-3743. (Pubitemid 47534316)
    • (2007) Chemical Reviews , vol.107 , Issue.9 , pp. 3715-3743
    • Famulok, M.1    Hartig, J.S.2    Mayer, G.3
  • 11
    • 12344306475 scopus 로고    scopus 로고
    • Intramers and aptamers: Applications in protein-function analyses and potential for drug screening
    • DOI 10.1002/cbic.200400299
    • Famulok, M. and Mayer, G. (2005) Intra-mers and aptamers: applications in protein-function analyses and potential for drug screening. ChemBioChem 6, 19-26. (Pubitemid 40128630)
    • (2005) ChemBioChem , vol.6 , Issue.1 , pp. 19-26
    • Famulok, M.1    Mayer, G.2
  • 12
    • 34447129727 scopus 로고    scopus 로고
    • Five- and six-membered conformationally locked 2′,4′- carbocyclic ribo-thymidines: Synthesis, structure, and biochemical studies
    • DOI 10.1021/ja071106y
    • Srivastava, P., Barman, J., Pathmasiri, W., Plashkevych, O., Wenska, M. and Chatto-padhyaya, J. (2007) Five-and six-membered conformationally locked 2,4-carbocyclic ribo-thymidines: synthesis, structure, and biochemical studies. J. Am. Chem. Soc. 129, 8362-8379. (Pubitemid 47035147)
    • (2007) Journal of the American Chemical Society , vol.129 , Issue.26 , pp. 8362-8379
    • Srivastava, P.1    Barman, J.2    Pathmasiri, W.3    Plashkevych, O.4    Wenska, M.5    Chattopadhyaya, J.6
  • 13
    • 34547619754 scopus 로고    scopus 로고
    • A chemical synthesis of LNA-2,6-diaminopurine riboside, and the influence of 2′-O-2,6-diaminopurine and LNA-2,6-diaminopurine ribosides on the thermodynamic properties of 2′O-methyl RNA/RNA heteroduplexes
    • DOI 10.1093/nar/gkm421
    • Pasternak, A., Kierzek, E., Pasternak, K., Turner, D.H. and Kierzek, R. (2007) A chemical synthesis of LNA-2,6-diaminopurine riboside, and the influence of 2'-O-methyl-2,6-diaminopurine and LNA-2,6-diamino-purine ribosides on the thermodynamic properties of 2-O-methyl RNA/RNA het-eroduplexes. Nucleic Acids Res. 35, 4055-4063. (Pubitemid 47244626)
    • (2007) Nucleic Acids Research , vol.35 , Issue.12 , pp. 4055-4063
    • Pasternak, A.1    Kierzek, E.2    Pasternak, K.3    Turner, D.H.4    Kierzek, R.5
  • 17
    • 35649014422 scopus 로고    scopus 로고
    • NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamer
    • DOI 10.1093/nar/gkm655
    • Lebars, I., Richard, T., Di Primo, C. and Toulmé, J.J. (2007) NMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified apta-mer. Nucleic Acids Res. 35, 6103-6114. (Pubitemid 350019242)
    • (2007) Nucleic Acids Research , vol.35 , Issue.18 , pp. 6103-6114
    • Lebars, I.1    Richard, T.2    Di Primo, C.3    Toulme, J.-J.4
  • 18
    • 33846821787 scopus 로고    scopus 로고
    • Systematic screening of LNA/2′-O-methyl chimeric derivatives of a TAR RNA aptamer
    • DOI 10.1016/j.febslet.2007.01.047, PII S0014579307000890
    • Di Primo, C., Rudloff, I., Reigadas, S., Arzumanov, A.A., Gait, M.J. and Toulmé, J.J. (2007) Systematic screening of LNA/2'-O-methyl chimeric derivatives of a TAR RNA aptamer. FEBS Lett. 581, 771-774. (Pubitemid 46216303)
    • (2007) FEBS Letters , vol.581 , Issue.4 , pp. 771-774
    • Di Primo, C.1    Rudloff, I.2    Reigadas, S.3    Arzumanov, A.A.4    Gait, M.J.5    Toulme, J.-J.6
  • 19
    • 34047151422 scopus 로고    scopus 로고
    • LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1
    • DOI 10.1016/j.bcmd.2006.11.008, PII S1079979606005638
    • Lebars, I., Richard, T., Di Primo, C. and Toulmé, J.J. (2007) LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element ofHIV-1. Blood Cells Mol. Dis. 38, 204-209. (Pubitemid 46518173)
    • (2007) Blood Cells, Molecules, and Diseases , vol.38 , Issue.3 , pp. 204-209
    • Lebars, I.1    Richard, T.2    Di Primo, C.3    Toulme, J.-J.4
  • 20
    • 33749359169 scopus 로고    scopus 로고
    • Aptamers targeted to an RNA hairpin show improved specificity compared to that of complementary oligonucleotides
    • DOI 10.1021/bi0606344
    • Darfeuille, F., Reigadas, S., Hansen, J.B., Orum, H., Di Primo, C. and Toulmé, J.J. (2006) Aptamers targeted to an RNA hairpin show improved specificity compared to that of complementary oligonucleotides. Biochemistry 45, 12076-12082. (Pubitemid 44497833)
    • (2006) Biochemistry , vol.45 , Issue.39 , pp. 12076-12082
    • Darfeuille, F.1    Reigadas, S.2    Hansen, J.B.3    Orum, H.4    Di Primo, C.5    Toulme, J.-J.6
  • 21
    • 0036606669 scopus 로고    scopus 로고
    • Design and characterization of decoy oligonucleotides containing locked nucleic acids
    • Crinelli, R., Bianchi, M., Gentilini, L. and Magnani, M. (2002) Design and characterization of decoy oligonucleotides containing locked nucleic acids. Nucleic Acids Res. 30, 2435-2443. (Pubitemid 34618995)
    • (2002) Nucleic Acids Research , vol.30 , Issue.11 , pp. 2435-2443
    • Crinelli, R.1    Bianchi, M.2    Gentilini, L.3    Magnani, M.4
  • 22
    • 3042651091 scopus 로고    scopus 로고
    • Transcription factor decoy oligonucleotides modified with locked nucleic acids: An in vitro study to reconcile biostability with binding affinity
    • DOI 10.1093/nar/gkh503
    • Crinelli, R., Bianchi, M., Gentilini, L., Palma, L., Sørensen, M.D., Bryld, T., Babu, R.B., Arar, K., Wengel, J. and Magnani, M. (2004) Transcription factor decoy oligonu-cleotides modified with locked nucleic acids: an in vitro study to reconcile biostability with binding affinity. Nucleic Acids Res. 32, 1874-1885. (Pubitemid 38842534)
    • (2004) Nucleic Acids Research , vol.32 , Issue.6 , pp. 1874-1885
    • Crinnelli, R.1    Bianchi, M.2    Gentilini, L.3    Palma, L.4    Sorensen, M.D.5    Bryld, T.6    Babu, R.B.7    Arar, K.8    Wengel, J.9    Magnani, M.10
  • 24
    • 0003955032 scopus 로고
    • Oli-gonucleotides and analogues
    • Eckstein, F. (Ed.), IRL, Oxford
    • Brown, T. and Brown, D. J. S. (1991) Oli-gonucleotides and analogues. A Practical Approach, Eckstein, F. (Ed.), IRL, Oxford, 1-24.
    • (1991) A Practical Approach , pp. 1-24
    • Brown, T.1    Brown, D.J.S.2
  • 25
    • 0002291648 scopus 로고    scopus 로고
    • Beaucage, S.L., Bergstrom, D.E., Herdewijn, P., and Matsuda, A. (Eds.). John Wiley, New York
    • Beaucage, S.L. and Caruthers, M.H. (2000) Current protocols in nucleic acid chemistry, Beaucage, S.L., Bergstrom, D.E., Herde-wijn, P., and Matsuda, A. (Eds.). John Wiley, New York, pp. 3.3.1-3.3.20.
    • (2000) Current Protocols in Nucleic Acid Chemistry , pp. 331-3320
    • Beaucage, S.L.1    Caruthers, M.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.