FTO genotype and weight gain in obese and normal weight adults from a norwegian population based cohort (the HUNT study)

Experimental and Clinical Endocrinology and Diabetes

Volumn 118, Issue 9, 2010, Pages 649-652

  Wangensteen, T ^a,b   Egeland, T ^b,c   Akselsen, H ^a   Holmen, J ^d   Undlien, D ^a,b   Retterstol L ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO METROPOLITAN UNIVERSITY   (Norway)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

FTO; genetics; longitudinal; obesity; rs1421085; weight gain

Indexed keywords

FAT MASS AND OBESITY ASSOCIATED PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BODY MASS; BODY WEIGHT; COHORT ANALYSIS; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NORWAY; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WAIST CIRCUMFERENCE; WEIGHT CONTROL; WEIGHT GAIN;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; GENOTYPE; HUMANS; IDEAL BODY WEIGHT; MALE; MIDDLE AGED; NORWAY; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; WEIGHT GAIN;

EID: 77958149766     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0030-1249636     Document Type: Article

References (14)

1. Cecil JE, Tavendale R, Watt P, et al. An obesity-associated FTO gene variant and increased energy intake in children. New England Journal of Medicine 2008 359 24 2558-2566
2. Dina C, Meyre D, Gallina S, et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nature Genetics 2007 39 6 724-726
3. Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007 316 5826 889-894
4. Hinney A, Nguyen TT, Scherag A, et al. Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS.ONE 2007 2 12 e1361
5. Holmen J, Midthjell K, Kruger O, et al. The Nord-Trøndelag Health Study 199597 (HUNT2): objectives, contents, methods and participation. Norw J Epidemiol 2003 13 1 19-32
6. Hunt SC, Stone S, Xin Y, et al. Association of the FTO gene with BMI. Obesity (Silver.Spring) 2008 16 4 902-904
7. Jess T, Zimmermann E, Kring SI, et al. Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study. Int J Obes (Lond) 2008 32 9 1388-1394
8. Marvelle AF, Lange LA, Qin L, et al. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. Diabetes 2008 57 7 1987-1991
9. Peeters A, Beckers S, Verrijken A, et al. Variants in the FTO gene are associated with common obesity in the Belgian population. Mol Genet Metab 2008 93 4 481-484
10. Price RA, Li WD, Zhao H. FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs. BMC Med Genet 2008 9 4
11. Qi L, Kang K, Zhang C, et al. Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test. Diabetes 2008 57 11 3145-3151
12. Rampersaud E, Mitchell BD, Pollin TI, et al. Physical activity and the association of common FTO gene variants with body mass index and obesity. Archives of Internal Medicine 2008 168 16 1791-1797
13. Scuteri A, Sanna S, Chen WM, et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS.Genet 2007 3 7 e115
14. Tabara Y, Osawa H, Guo H, et al. Prognostic significance of FTO genotype in the development of obesity in Japanese: the J-SHIPP study. Int J Obes (Lond) 2009