Zona pellucida-induced acrosome reaction in human spermatozoa is potentiated by glycodelin-A via down-regulation of extracellular signal-regulated kinases and up-regulation of zona pellucida-induced calcium influx

Human Reproduction

Volumn 25, Issue 11, 2010, Pages 2721-2733

  Chiu, Philip C N ^a   Wong, Ben S T ^a   Lee, Cheuk Lun ^a   Lam, Kevin K W ^a   Chung, Man Kin ^b   Lee, Kai Fai ^a   Koistinen, Riitta ^c   Koistinen, Hannu ^c   Gupta, Satish K ^d   Seppälä, Markku ^c   Yeung, William S B ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

ERK; glycodelin; intracellular calcium; sperm acrosome reaction; zona pellucida

Indexed keywords

ADENYLATE CYCLASE; CALCIUM; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PLACENTA PROTEIN 14;

ACROSOME REACTION; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MALE; MALE INFERTILITY; PROTEIN PURIFICATION; SPERMATOZOON; UPREGULATION; ZONA PELLUCIDA;

PISUM SATIVUM;

EID: 77958140629     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deq243     Document Type: Article

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