Genetic control of differential baseline breathing pattern

Journal of Applied Physiology

Volumn 82, Issue 3, 1997, Pages 874-881

  Tankersley, Clarke G ^a,c   Fitzgerald, Robert S ^a   Levitt, Roy C ^b   Mitzner, Wayne A ^a   Ewart, Susan L ^b   Kleeberger, Steven R ^a  

^a The Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

breathing frequency; BXH recombinant inbred strains; control of ventilation; inbred mice; respiratory timing

Indexed keywords

ARTICLE; BREATHING PATTERN; BREATHING RATE; FEMALE; GENE LOCUS; GENE SEGREGATION; GENETIC REGULATION; GENETIC VARIABILITY; INSPIRATORY RESERVE VOLUME; MALE; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROGENY; RAT; STRAIN DIFFERENCE; TIDAL VOLUME;

EID: 0031002243     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.82.3.874     Document Type: Article

References (32)

1. Agostoni, E., F. F. Thimm, and W. O. Fenn. Comparative features of the mechanics of breathing. J. Appl. Physiol. 14: 679-683, 1959.
2. Bennett, F. M., and S. M. Tenney. Comparative mechanics of mammalian respiratory system. Respir. Physiol. 49: 131-140, 1982.
3. Bentivoglio, A. R., M. C. Altavista, R. Granata, and A. Albanese. Genetically determined cholinergic deficiency in the forebrain of C57BL/6 mice. Brain Res. 637: 181-189, 1994.
4. Bland, S., L. Lazerou, G. Dyck, and R. M. Cherniack. The influence of the "chest wall" on respiratory rate and depth. Respir. Physiol. 3: 47-54, 1967.
5. Crosfill, M. L., and J. G. Widdicombe. Physical characteristics of the chest and lungs and the work of breathing in different mammalian species. J. Physiol. (Lond.) 158: 1-14, 1961.
6. DiSilvestre, D., S. R. Kleeberger, J. Johns, and R. C. Levitt. Structure and DNA sequence of the mouse MnSOD gene. Mamm. Genome 6: 281-284, 1995.
7. Drorbaugh, J. E., and W. O. Fenn. A barometric method for measuring ventilation in newborn infants. Pediatrics 16: 81-86, 1955.
8. Eisele, J. H., B. Wuyam, G. Savourey, J. Eterradossi, J. H. Bittel, and G. Benchetrit. Individuality of breathing patterns during hypoxia and exercise. J. Appl. Physiol. 72: 2446-2453, 1992.
9. Elston, R. C. The genetic analysis of quantitative trait differences between two homozygous lines. Genetics 108: 733-744, 1984.
10. Epstein, M. A. F., and R. A. Epstein. A theoretical analysis of the barometric method for measurement of tidal volume. Respir. Physiol. 32: 105-120, 1978.
11. Guyton, A. C. Measurement of the respiratory volumes of laboratory animals. Am. J. Physiol. 150: 70-77, 1947.
12. Hamosh, A., and M. Corey. Correlation between genotype and phenotype in patients with cystic fibrosis. N. Engl. J. Med. 329: 1308-1313, 1993.
13. Kelsen, S. G., M. D. Altose, and N. S. Cherniack. Interaction of lung volume and chemical drive on respiratory muscle EMG and respiratory timing. J. Appl. Physiol. 42: 287-294, 1977.
14. 1 offspring. Am. Rev. Respir. Dis. 139: 1238-1243, 1989.
15. Kleeberger, S. R., R. C. Levitt, and L. Zhang. Susceptibility to ozone-induced inflammation. II. Separate loci control responses to acute and subacute exposures. Am. J. Physiol. 264 (Lung Cell. Mol. Physiol. 8): L21-L26, 1993.
16. Levitt, R. C., W. Mitzner, and S. R. Kleeberger. A genetic approach to the study of lung physiology: understanding biological variability in airway responsiveness. Am. J. Physiol. 258 (Lung Cell. Mol. Physiol. 2): L157-L164, 1990.
17. Lydic, R., H. A. Baghdoyan, and Z. Lorinc. Microdialysis of cat pons reveals enhanced acetylcholine release during state-dependent respiratory depression. Am. J. Physiol. 261 (Regulatory Integrative Comp. Physiol. 30): R766-R770, 1991.
18. Mead, J. Control of respiratory frequency. J. Appl. Physiol. 15: 325-336, 1960.
19. Otis, A. B., W. O. Fenn, and H. Rahn. Mechanics of breathing in man. J. Appl. Physiol. 2: 592-607, 1950.
20. Otis, A. B., C. B. McKerrow, R. A. Barlett, J. Mead, M. B. McIlroy, N. J. Selverstone, and E. P. Radford. Mechanical factors in distribution of pulmonary ventilation. J. Appl. Physiol. 8: 427-443, 1956.
21. Quetelet, M. A. A Treatise on Man and the Development of His Faculties. Edinburgh: Chambers, 1842, p.70-71.
22. SAGE. Statistical Analysis for Genetic Epidemiology, version 2.2. Cleveland, OH: Department of Epidemiology and Biostatistics, Case Western Reserve University, 1994.
23. Schwab, C., G. Brückner, C. Castellano, A. Oliverio, and D. Biesold. Different levels of acetylcholinesterase and choline acetyltransferase activities in C57B1/6 and DBA/2 mice are not accompanied with different density of cortical acetylcholinesterase reactive fibers. Neurochem. Res. 15: 1127-1133, 1990.
24. Shea, S. A., G. Benchetrit, T. Pham Dinh, R. D. Hamilton, and A. Guz. The breathing patterns of identical twins. Respir. Physiol. 75: 211-224, 1989.
25. Silver, J. Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains. J. Heredity 76: 436-440, 1985.
26. Smith, J. C., H. H. Ellenberger, K. Ballanyi, D. W. Richter, and J. L. Feldman. Pre-Botzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254: 726-729, 1991.
27. Stewart, J., and R. C. Elston. Biometrical genetics with one or two loci: the inheritance of physiological characters in mice. Genetics 73: 675-693, 1973.
28. Swank, R. T., and D. W. Bailey. Recombinant inbred lines: value in the genetic analysis of biochemical variants. Science 181: 1249-1252, 1973.
29. Tankersley, C. G., R. S. Fitzgerald, and S. R. Kleeberger. Differential control of ventilation among inbred mice strains. Am. J. Physiol. 267 (Regulatory Integrative Comp. Physiol. 36): R1371-R1377, 1994.
30. Tankersley, C. G., R. S. Fitzgerald, W. A. Mitzner, and S. R. Kleeberger. Hypercapnic ventilatory responses in mice differentially susceptible to acute ozone exposure. J. Appl. Physiol. 75: 2613-2619, 1993.
31. Taylor, B. A. Recombinant inbred strains. In: Genetic Variants and Strains of the Laboratory Mouse (2nd ed. ), edited by M. Lyon and A. G. Searle. New York: Oxford Univ. Press, 1989, p. 773-779.
32. Wright, S. Systems of mating. V. General considerations. Genetics 6: 167-178, 1921.