XRCC1 gene polymorphism for prediction of response and prognosis in the multimodality therapy of patients with locally advanced rectal cancer

Journal of Surgical Research

Volumn 164, Issue 1, 2010, Pages

  Grimminger, Peter P ^a   Brabender, Jan ^a   Warnecke Eberz, Ute ^a   Narumiya, Kosuke ^a   Wandhöfer, Christoph ^a   Drebber, Uta ^a   Bollschweiler, Elfriede ^a   Hölscher, Arnulf H ^a   Metzger, Ralf ^a   Vallböhmer, Daniel ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

biomarker; locally advanced rectal cancer; neoadjuvant radiochemotherapy; prognostic and predictive; XRCC1

Indexed keywords

FLUOROURACIL; GENOMIC DNA; XRCC1 PROTEIN;

ADULT; ADVANCED CANCER; ARTICLE; CANCER LOCALIZATION; CELL VIABILITY; CONTROLLED STUDY; DNA EXTRACTION; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; RECTUM CANCER; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR CELL;

CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; DNA-BINDING PROTEINS; FEMALE; GENOTYPE; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; PREOPERATIVE CARE; PROGNOSIS; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TUMOR MARKERS, BIOLOGICAL;

EID: 77958102412     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2010.08.002     Document Type: Article

References (43)

1. A. Jemal, R. Siegel, and E. Ward Cancer statistics, 2009 CA Cancer J Clin 59 2009 225
2. L.L. Gunderson, D.J. Sargent, and J.E. Tepper Impact of T and N substage on survival and disease relapse in adjuvant rectal cancer: A pooled analysis Int J Radiat Oncol Biol Phys 54 2002 386
3. M. Mohiuddin, J. Marks, and G. Marks Management of rectal cancer: Short- vs. long-course preoperative radiation Int J Radiat Oncol Biol Phys 72 2008 636
4. T.E. Read, M.S. McNevin, and E.K. Gross Neoadjuvant therapy for adenocarcinoma of the rectum: Tumor response and acute toxicity Dis Colon Rectum 44 2001 513
5. N.A. Janjan, V.S. Khoo, and J. Abbruzzese Tumor downstaging and sphincter preservation with preoperative chemoradiation in locally advanced rectal cancer: The M.D. Anderson Cancer Center experience Int J Radiat Oncol Biol Phys 44 1999 1027
6. J.S. Kim, J.S. Kim, and M.J. Cho Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer Int J Radiat Oncol Biol Phys 54 2002 403
7. R. Sauer, H. Becker, and W. Hohenberger Preoperative versus postoperative chemoradiotherapy for rectal cancer N Engl J Med 351 2004 1731
8. H.J. Chang, K.H. Jung, and D.Y. Kim Bax, a predictive marker for therapeutic response to preoperative chemoradiotherapy in patients with rectal carcinoma Hum Pathol 36 2005 364
9. G. Esposito, S. Pucciarelli, and R. Alaggio P27kip1 expression is associated with tumor response to preoperative chemoradiotherapy in rectal cancer Ann Surg Oncol 8 2001 311
10. J. Giralt, M. de las Heras, and L. Cerezo The expression of epidermal growth factor receptor results in a worse prognosis for patients with rectal cancer treated with preoperative radiotherapy: A multicenter, retrospective analysis Radiother Oncol 74 2005 101
11. H.J. Lenz, K.D. Danenberg, and C.G. Leichman p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site Clin Cancer Res 4 1998 1227
12. A.J. McIlwrath, P.A. Vasey, and G.M. Ross Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity Cancer Res 54 1994 3718
13. B. Rau, I. Sturm, and H. Lage Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy J Clin Oncol 21 2003 3391
14. D. Salonga, K.D. Danenberg, and M. Johnson Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase Clin Cancer Res 6 2000 1322
15. R.P. Saw, M. Morgan, and D. Koorey p53, deleted in colorectal cancer gene, and thymidylate synthase as predictors of histopathologic response and survival in low, locally advanced rectal cancer treated with preoperative adjuvant therapy Dis Colon Rectum 46 2003 192
16. K.L. Spindler, J.N. Nielsen, and J. Lindebjerg Germline polymorphisms may act as predictors of response to preoperative chemoradiation in locally advanced T3 rectal tumors Dis Colon Rectum 50 2007 1363
17. J. Stoehlmacher, E. Goekkurt, and U. Mogck Thymidylate synthase genotypes and tumor regression in stage II/III rectal cancer patients after neoadjuvant fluorouracil-based chemoradiation Cancer Lett 272 2008 221
18. J.S. Kim, J.M. Kim, and S. Li Epidermal growth factor receptor as a predictor of tumor downstaging in locally advanced rectal cancer patients treated with preoperative chemoradiotherapy Int J Radiat Oncol Biol Phys 66 2006 195
19. K.L. Spindler, J.N. Nielsen, and J. Lindebjerg Prediction of response to chemoradiation in rectal cancer by a gene polymorphism in the epidermal growth factor receptor promoter region Int J Radiat Oncol Biol Phys 66 2006 500
20. R.D. Wood, M. Mitchell, and J. Sgouros Human DNA repair genes Science 291 2001 1284
21. Z. Yu, J. Chen, and B.N. Ford Human DNA repair systems: An overview Environ Mol Mutagen 33 1999 3
22. J.H. Hoeijmakers Genome maintenance mechanisms for preventing cancer Nature 411 2001 366
23. M. Masson, C. Niedergang, and V. Schreiber XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage Mol Cell Biol 18 1998 3563
24. L.H. Thompson, and M.G. West XRCC1 keeps DNA from getting stranded Mutat Res 459 2000 1
25. M.R. Shen, I.M. Jones, and H. Mohrenweiser Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans Cancer Res 58 1998 604
26. U. Warnecke-Eberz, D. Vallbohmer, and H. Alakus ERCC1 and XRCC1 gene polymorphisms predict response to neoadjuvant radiochemotherapy in esophageal cancer J Gastrointest Surg 13 2009 1411
27. M. Fernet, and J. Hall Genetic biomarkers of therapeutic radiation sensitivity DNA Repair (Amst) 3 2004 1237
28. P.M. Schneider, S.E. Baldus, and R. Metzger Histomorphologic tumor regression and lymph node metastases determine prognosis following neoadjuvant radiochemotherapy for esophageal cancer: Implications for response classification Ann Surg 242 2005 684
29. M. Thomas, C. Rube, and M. Semik Impact of preoperative bimodality induction including twice-daily radiation on tumor regression and survival in stage III non-small-cell lung cancer J Clin Oncol 17 1999 1185
30. K. Junker, K. Langner, and F. Klinke Grading of tumor regression in non-small-cell lung cancer: Morphology and prognosis Chest 120 2001 1584
31. K. Becker, J.D. Mueller, and C. Schulmacher Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy Cancer 98 2003 1521
32. E. Bollschweiler Benefits and limitations of Kaplan-Meier calculations of survival chance in cancer surgery Langenbecks Arch Surg 388 2003 239
33. E. Kaplan, and P. Meier Nonparametric estimation from incomplete observations J Am Stat Assoc 53 1958 457
34. S.J. Pocock, T.C. Clayton, and D.G. Altman Survival plots of time-to-event outcomes in clinical trials: Good practice and pitfalls Lancet 359 2002 1686
35. D. Sebag-Montefiore, R.J. Stephens, and R. Steele Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): A multicenter, randomized trial Lancet 373 2009 811
36. X.D. Cheng, W.G. Lu, and F. Ye The association of XRCC1 gene single nucleotide polymorphisms with response to neoadjuvant chemotherapy in locally advanced cervical carcinoma J Exp Clin Cancer Res 28 2009 91
37. H.H. Chung, M.K. Kim, and J.W. Kim P. XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer Gynecol Oncol 103 2006 1031
38. N. Moullan, D.G. Cox, and S. Angele Polymorphisms in the DNA repair gene XRCC1, breast cancer risk, and response to radiotherapy Cancer Epidemiol Biomarkers Prev 12 2003 1168
39. Y.A. Park, S.K. Sohn, and J. Seong Serum CEA as a predictor for the response to preoperative chemoradiation in rectal cancer J Surg Oncol 93 2006 145
40. G.L. Cascini, A. Avallone, and P. Delrio 18F-FDG PET is an early predictor of pathologic tumor response to preoperative radiochemotherapy in locally advanced rectal cancer J Nucl Med 47 2006 1241
41. P. Das, J.M. Skibber, and M.A. Rodriguez-Bigas Predictors of tumor response and downstaging in patients who receive preoperative chemoradiation for rectal cancer Cancer 109 2007 1750
42. F.M. Smith, J.V. Reynolds, and E.W. Kay COX-2 overexpression in pretreatment biopsies predicts response of rectal cancers to neoadjuvant radiochemotherapy Int J Radiat Oncol Biol Phys 64 2006 466
43. B.M. Ghadimi, M. Grade, and M.J. Difilippantonio Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy J Clin Oncol 23 2005 1826