Fluorescent-tagged sp2-iminosugars with potent β-glucosidase inhibitory activity

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 21, 2010, Pages 7439-7445

  Aguilar Moncayo, Matilde ^a   García Moreno, M Isabel ^a   Stütz, Arnold E ^b   García Fernández, José M ^c   Wrodnigg, Tanja M ^b   Mellet, Carmen Ortiz ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^c INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

Author keywords

Fluorescence resonance energy transfer (FRET); Glycosidase inhibitors; Iminosugars; Photolabeling

Indexed keywords

BETA GLUCOSIDASE; BETA GLUCOSIDASE INHIBITOR; ENZYME INHIBITOR; FLUORESCENT DYE; IMINOSUGAR; NOJIRIMYCIN; UNCLASSIFIED DRUG; 1 DEOXYNOJIRIMYCIN; DRUG DERIVATIVE; MULTIENZYME COMPLEX; NARINGINASE;

ARTICLE; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; FLUORESCENCE RESONANCE ENERGY TRANSFER; PHOTOAFFINITY LABELING; ANIMAL; CATTLE; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; SYNTHESIS;

BOVINAE;

1-DEOXYNOJIRIMYCIN; ANIMALS; BETA-GLUCOSIDASE; CATTLE; ENZYME INHIBITORS; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; IMINO SUGARS; MULTIENZYME COMPLEXES;

EID: 77957992409     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.09.003     Document Type: Article

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