Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 1, 2010, Pages 267-273

  Scherpenzeel, Monique van ^a   van den Berg, Richard J B H N ^b   Donker Koopman, Wilma E ^c   Liskamp, Rob M J ^a   Aerts, Johannes M F G ^c   Overkleeft, Herman S ^b   Pieters, Roland J ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Glucosidases; Photolabeling; Proteomics probes

Indexed keywords

1 DEOXYNOJIRIMYCIN; BETA GLUCOSIDASE; GLUCOSE; GLUCOSYLCERAMIDASE;

ALKYLATION; ARTICLE; CELL LYSATE; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ASSAY; ENZYME BINDING; ENZYME INHIBITION; HUMAN; HUMAN CELL; SYNTHESIS;

BACTERIA; GLUCOSE; GLUCOSYLCERAMIDASE; HELA CELLS; HUMANS; IMINO SUGARS; LYSOSOMES; PHOTOCHEMISTRY; PROTEIN BINDING;

EID: 72049120645     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.10.060     Document Type: Article

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