Epigenetic regulation of adipocyte differentiation and adipogenesis

Journal of Zhejiang University: Science B

Volumn 11, Issue 10, 2010, Pages 784-791

  Li, Hong Xing ^a,b   Xiao, Lei ^a   Wang, Cheng ^c   Gao, Jia Li ^a   Zhai, Yong Gong ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Adipogenesis; Differentiation; DNA methylation; Epigenetic regulation; Histone modification

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN D1; CYCLIN D3; DNA; GLUCOSE TRANSPORTER 4; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE DEACETYLASE 3; HISTONE H3; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOBLASTOMA PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 5; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR FKHR; CCAAT ENHANCER BINDING PROTEIN ALPHA;

ADIPOCYTE; ADIPOGENESIS; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN 3T3; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; EPIGENETICS; FIBROBLAST; MESENCHYMAL STEM CELL; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; REVIEW; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WHITE ADIPOSE TISSUE; ANIMAL; CYTOLOGY; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETICS; HUMAN; PHYSIOLOGY;

ADIPOCYTES; ADIPOGENESIS; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; EPIGENESIS, GENETIC; HUMANS; PPAR GAMMA; RETINOBLASTOMA PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION, GENETIC;

EID: 77957979916     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B0900401     Document Type: Review

References (57)

1. M. Armoni C. Harel S. Karni H. Chen F. Yoseph R. Marel M.J. Quon E. Karnieli 2006 FoxO1 represses peroxisome proliferator-activated receptor-γ1 and -γ2 gene promoters in primary adipocytes J. Biol. Chem. 281 29 19881 19891 10.1074/jbc.M600320200 16670091
2. R.R. Bowers J.W. Kim T.C. Otto M.D. Lane 2006 Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: role of the BMP-4 gene PNAS 103 35 13022 13027 10.1073/pnas.0605789103 16916928
3. A. Cederberg L.M. Gronning B. Ahren K. Tasken P. Carlsson S. Enerback 2001 FoxC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance Cell 106 5 563 573 10.1016/S0092-8674(01)00474-3 11551504
4. M.C. Cho K. Lee S.G. Paik D.Y. Yoon 2008 Peroxisome proliferators- activated receptor (PPAR) modulators and metabolic disorders PPAR Res. 2008 1 14 10.1155/2008/679137
5. Y.W. Cho S.H. Hong Q. Jin L.F. Wang J.E. Lee O. Gavrilova K. Ge 2009 Histone methylation regulator PTIP Is required for PPARγ and C/EBPα expression and adipogenesis Cell Metab. 10 1 27 39 10.1016/j.cmet.2009.05.010 19583951
6. P. Cornelius O.A. MacDougald M.D. Lane 1994 Regulation of adipocyte development Annu. Rev. Nutr. 14 1 99 129 10.1146/annurev.nu.14.070194.000531 7946535
7. A.C. D'Alessio I.C. Weaver M. Szyf 2007 Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes Mol. Cell. Biol. 27 7462 7474 10.1128/MCB.01120-07 17709385
8. G.J. Darlington S.E. Ross O.A. MacDougald 1998 The role of C/EBP genes in adipocyte differentiation J. Biol. Chem. 273 46 30057 30060 10.1074/jbc.273.46.30057 9804754
9. D.C. Dolinoy R.L. Jirtle 2008 Environmental epigenomics in human health and disease Environ. Mol. Mutagen. 49 1 4 8 10.1002/em.20366 18172876
10. S.R. Farmer 2006 Transcriptional control of adipocyte formation Cell Metabolism 4 4 263 273 10.1016/j.cmet.2006.07.001 17011499
11. J.N. Feige J. Auwerx 2007 Transcriptional coregulators in the control of energy homeostasis Trends Cell Biol. 17 6 292 301 10.1016/j.tcb.2007.04.001 17475497
12. K.E. Fox L.A. Colto P.F. Erickson J.E. Friedman H.C. Cha P. Keller O.A. MacDougald D.J. Klemm 2008 Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation J. Biol. Chem. 283 50 35096 35105 10.1074/jbc.M806423200 18957421
13. M. Fu M. Rao T. Bouras C. Wang K. Wu X. Zhang Z.P. Li T. Yao R.G. Pestell 2005 Cyclin D1 inhibits PPARγ-mediated adipogenesis through histone deacetylase recruitment J. Biol. Chem. 280 17 16934 16941 10.1074/jbc.M500403200 15713663
14. K. Fujiki F. Kano K. Shiota M. Murata 2009 Expression of the peroxisome proliferator activated receptor γ gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes BMC Biology 7 38 10.1186/1741-7007-7-38 19589179
15. V. Giandomenico M. Simonsson E. Gronroos J. Ericsson 2003 Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors Mol. Cell. Biol. 23 7 2587 2599 10.1128/MCB.23.7.2587- 2599.2003 12640139
16. H. Green O. Kehinde 1974 Sublines of mouse 3T3 cells that accumulate lipid Cell 1 3 113 116 10.1016/0092-8674(74)90126-3
17. H. Green O. Kehinde 1975 An established preadipose cell line and its differentiation in culture II Factors affecting the adipose conversion. Cell 5 1 19 27
18. H. Green O. Kehinde 1976 Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells Cell 7 1 105 113 10.1016/0092-8674(76) 90260-9 949738
19. H.P. Guan T. Ishizuka P.C. Chui M. Lehrke M.A. Lazar 2005 Corepressors selectively control the transcriptional activity of PPARγ in adipocytes Genes Dev. 19 4 453 461 10.1101/gad.1263305 15681609
20. W. Guo K.M. Zhang K. Tu Y.X. Li L. Zhu H.S. Xiao Y. Yang J.R. Wu 2009 Adipogenesis licensing and execution are disparately linked to cell proliferation Cell Res. 19 2 216 223 10.1038/cr.2008.319 19065151
21. J.B. Hansen C. Jorgensen R.K. Petersen P. Hallenborg R. de Matteis H.A. Boye N. Petrovic S. Enerback J. Nedergaard S. Cinti, et al. 2004 Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation PNAS 101 12 4112 4117 10.1073/pnas.0301964101 15024128
22. T. Horii S. Morita M. Kimura I. Hatada 2009 Epigenetic regulation of adipocyte differentiation by a Rho guanine nucleotide exchange factor, WGEF PLoS ONE 4 6 e5809 10.1371/journal.pone.0005809 19503838
23. H.J. Huang J.T. Donald 2007 Dynamic FoxO transcription factors J. Cell. Sci. 120 15 2479 2487 10.1242/jcs.001222 17646672
24. P.F. Johnson 2005 Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors J. Cell Sci. 118 12 2545 2555 10.1242/jcs.02459 15944395
25. S. Kajimura P. Seale T. Tomaru H. Erdjument-Bromage M.P. Cooper J.L. Ruas S. Chin P. Tempst M.A. Lazar B.M. Spiegelman 2008 Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex Genes Dev. 22 10 1397 1409 10.1101/gad.1666108 18483224
26. E.E. Kershaw J.S. Flier 2004 Adipose tissue as an endocrine organ J. Clin. Endocrinol. Metab. 89 6 2548 2556 10.1210/jc.2004-0395 15181022
27. T. Kouzarides 2007 Chromatin modifications and their function Cell 128 4 693 705 10.1016/j.cell.2007.02.005 17320507
28. Y.S. Lee D.H. Sohn D. Han H.W. Lee R.H. Seong J.B. Kim 2007 Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression Mol. Cell. Biol. 27 2 438 452 10.1128/MCB.00490-06 17074803
29. L. Liu Y.Y. Li T. Tollefsbol 2008 Gene-environment interactions and epigenetic basis of human diseases Curr. Issues Mol. Biol. 10 1 25 36 18525104
30. C. Luo Y. Yao R.J. Wang F.M. Yan D.X. Hu X.L. Zhang 2002 The use of mitochondrial cytochrome oxidase I (mtCOI) gene sequences for the identification of biotypes of Bemisia tabaci (Gennadius) in China Acta Entomol. Sin. 45 6 759 763
31. A. Marcos A. Montero S. Lopez-Varela G. Morande 2001 Eating disorders (obesity, anorexia nervosa, bulimia nervosa), immunity, and infection Nutr. Immun. Infect. Infants Child. 45 243 262
32. C. Martin Y. Zhang 2005 The diverse functions of histone lysine methylation Nat. Rev. Mol. Cell Biol. 6 11 838 849 10.1038/nrm1761 16261189
33. C. Müller C.F. Calkhoven X. Sha A. Leutz 2004 C/EBPα requires a SWI/SNF complex for proliferation arrest J. Biol. Chem. 279 8 7353 7358 10.1074/jbc.M312709200 14660596
34. M.M. Musri H. Corominola R. Casamitjana R. Gomis M. Parrizas 2006 Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes J. Biol. Chem. 281 25 17180 17188 10.1074/jbc.M601295200 16613853
35. M.M. Musri R. Gomis M. Párrizas 2007 Chromatin and chromatin-modifying proteins in adipogenesis Cell Biol. 85 4 397 410
36. G.J. Narlikar H.Y. Fan R.E. Kingston 2002 Cooperation between complexes that regulate chromatin structure and transcription Cell 108 4 475 487 10.1016/S0092-8674(02)00654-2 11909519
37. C. Nerlov 2008 C/EBPs: recipients of extracellular signals through proteome modulation Curr. Opin. Cell Biol. 20 2 180 185 10.1016/j.ceb.2008.02. 002 18358708
38. A. Noer A.L. Sorensen A.C. Boquest P. Collas 2006 Stable CpG hypomethylation of adipogenic promoters in freshly isolated, cultured, and differentiated mesenchymal stem cells from adipose tissue Mol. Biol. Cell 17 8 3543 3556 10.1091/mbc.E06-04-0322 16760426
39. Y. Okada H. Sakaue T. Nagare M. Kasuga 2009 Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation Kobe J. Med. Sci. 54 5 241 249
40. J. Qiu 2009 Cellular differentiation: a two-stage procedure Cell Res. 19 216 223 10.1038/cr.2009.93
41. A.S. Quina M. Buschbeck L.D. Croce 2007 Chromatin structure and epigenetics Biol. Reprod 72 11 1563 1569
42. D.P. Ramji P. Foka 2002 CCAAT/enhancer-binding proteins: structure, function and regulation Biochem. J. 365 561 575 12006103
43. E.D. Rosen O.A. MacDougald 2006 Adipocyte differentiation from the inside out Nat. Rev. Mol. Cell Biol. 7 12 885 896 10.1038/nrm2066 17139329
44. N. Rotman H.T. Zofia S. Lucke J. Feige L. Gelman B. Desvergne W. Wahli 2008 PPAR disruption: cellular mechanisms and physiological consequences Chimia 62 5 340 344 10.2533/chimia.2008.340
45. H. Sakamoto Y. Kogo J. Ohgane N. Hattori S. Yagi S. Tanaka K. Shiota 2008 Sequential changes in genome-wide DNA methylation status during adipocyte differentiation Biochem. Biophys. Res. Commun. 366 2 360 366 10.1016/j.bbrc.2007.11.137 18062916
46. N. Salma H. Xiao E. Mueller A.N. Imbalzano 2004 Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the PPARγ nuclear hormone receptor Mol. Cell. Biol. 24 11 4651 4663 10.1128/MCB.24.11.4651-4663.2004 15143161
47. N. Salma H. Xiao A.N. Imbalzano 2006 Temporal recruitment of C/EBPs to early and late adipogenic promoters in vivo J. Mol. Endocrinol. 36 1 139 151 10.1677/jme.1.01918 16461934
48. D.A. Sarruf I. Iankova A. Abella S. Assou S. Miard L. Fajas 2005 Cyclin D3 promotes adipogenesis through activation of PPARγ Mol. Cell. Biol. 25 22 9985 9995 10.1128/MCB.25.22.9985-9995.2005 16260612
49. A. Scimè G. Grenier M.S. Huh M.A. Gillespie L. Bevilacqua M.E. Harper M. Rudnicki 2005 Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1α Cell Metab. 2 5 283 295 10.1016/j.cmet.2005.10.002 16271529
50. Q.Q. Tang T.C. Otto M.D. Lane 2003 CCAAT/enhancer-binding protein β is required for mitotic clonal expansion during adipogenesis PNAS 100 3 850 855 10.1073/pnas.0337434100 12525691
51. Q.Q. Tang M. Gronborg H. Huang J.W. Kim T.C. Otto A. Pandey M.D. Lane 2005 Sequential phosphorylation of C/EBPβ by MAPK and GSK3β is required for adipogenesis PNAS 102 28 9766 9771 10.1073/pnas.0503891102 15985551
52. G.L. Wang X. Shi E. Salisbury Y. Sun J.H. Albrecht R.G. Smith N.A. Timchenko 2006 Cyclin D3 maintains growth-inhibitory activity of C/EBPα by stabilizing C/EBPα-cdk2 and C/EBPα-Brm complexes Mol. Cell. Biol. 26 7 2570 2582 10.1128/MCB.26.7.2570-2582.2006 16537903
53. Y. Xie X.P. Zhou Z.K. Zhang Y.J. Qi 2002 Tobacco curly shoot virus isolated in Yunnan is a distinct species of Begomovirus Chin. Sci. Bull. 47 3 197 200 10.1360/02tb9047
54. L.H. Yang T.M. Chen S.T. Yu Y.R. Chen 2007 Olanzapine induces SREBP-1-related adipogenesis in 3T3-L1 cells Pharmacol. Res. 56 3 202 208 10.1016/j.phrs.2007.05.007 17651982
55. N. Yokomori M. Tawata T. Onaya 2002 DNA demethylation modulates mouse leptin promoter activity during the differentiation of 3T3-L1 cells Diabetologia 45 1 140 148 10.1007/s125-002-8255-4 11845234
56. C. Yu K. Markan K.A. Temple D. Deplewski M.J. Brady R.N. Cohen 2005 The nuclear receptor corepressors NCoR and SMRT decrease PPARγ transcriptional activity and repress 3T3-L1 adipogenesis J. Biol. Chem. 280 14 13600 13605 10.1074/jbc.M409468200 15691842
57. Y. Zuo L. Qiang S.R. Farmer 2006 Activation of C/EBPα expression by C/EBPβ during adipogenesis requires a PPARγ-associated repression of HDAC1 at the C/EBPα gene promoter J. Biol. Chem. 281 12 7960 7967 10.1074/jbc.M510682200 16431920