-
1
-
-
77958022110
-
-
Zometa package insert. East Hanover, NJ: Novartis Pharmaceuticals Corporation
-
Zometa [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2009
-
(2009)
-
-
-
2
-
-
0042914647
-
Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial-the zoledronic acid lung cancer and other solid tumors study group
-
Rosen, L. S.; Gordon, D.; Tchekmedyian, S.; Yanagihara, R.; Hirsh, V.; Krzakowski, M.; Pawlicki, M.; de Souza, P.; Zheng, M.; Urbanowitz, G.; Reitsma, D.; Seaman, J. J. Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial-the zoledronic acid lung cancer and other solid tumors study group. J Clin Oncol 2003, 21, 3150-3157.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 3150-3157
-
-
Rosen, L.S.1
Gordon, D.2
Tchekmedyian, S.3
Yanagihara, R.4
Hirsh, V.5
Krzakowski, M.6
Pawlicki, M.7
Souza, P.8
Zheng, M.9
Urbanowitz, G.10
Reitsma, D.11
Seaman, J.J.12
-
3
-
-
2642521168
-
Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung cancer and other solid tumors: A randomized, phase III, double-blind, placebo-controlled trial
-
Rosen, L. S.; Gordon, D.; Tchekmedyian, N. S.; Yanagihara, R.; Hirsh, V.; Krzakowski, M.; Pawlicki, M.; De Souza, P.; Zheng, M.; Urbanowitz, G.; Reitsma, D.; Seaman, J. Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung cancer and other solid tumors: a randomized, phase III, double-blind, placebo-controlled trial. Cancer 2004, 100, 2613-2621.
-
(2004)
Cancer
, vol.100
, pp. 2613-2621
-
-
Rosen, L.S.1
Gordon, D.2
Tchekmedyian, N.S.3
Yanagihara, R.4
Hirsh, V.5
Krzakowski, M.6
Pawlicki, M.7
De Souza, P.8
Zheng, M.9
Urbanowitz, G.10
Reitsma, D.11
Seaman, J.12
-
4
-
-
5444242637
-
Bisphosphonates: Preclinical review
-
Green, J. R. Bisphosphonates: preclinical review. Oncologist 2004. 9 (suppl 4), S3-S13.
-
(2004)
Oncologist
, vol.9
, Issue.4 SUPPL.
-
-
Green, J.R.1
-
5
-
-
63749110469
-
The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts
-
Hirbe, A. C.; Roelofs, A. J.; Floyd, D. H.; Deng, H.; Becker, S. N.; Lanigan, L. G.; Apicelli, A. J.; Xu, Z.; Prior, J. L.; Eagleton, M. C.; Piwnica-Worms, D.; Rogers, M. J.; Weilbaecher, K. The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts. Bone 2009, 44, 908-916.
-
(2009)
Bone
, vol.44
, pp. 908-916
-
-
Hirbe, A.C.1
Roelofs, A.J.2
Floyd, D.H.3
Deng, H.4
Becker, S.N.5
Lanigan, L.G.6
Apicelli, A.J.7
Xu, Z.8
Prior, J.L.9
Eagleton, M.C.10
Piwnica-Worms, D.11
Rogers, M.J.12
Weilbaecher, K.13
-
6
-
-
3042729728
-
Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model
-
Hiraga, T.; Williams, P. J.; Ueda, A.; Tamura, D.; Yoneda, T. Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model. Clin Cancer Res 2004, 10, 4559-4567.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4559-4567
-
-
Hiraga, T.1
Williams, P.J.2
Ueda, A.3
Tamura, D.4
Yoneda, T.5
-
7
-
-
4944239035
-
An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
-
Giraudo, E.; Inoue, M.; Hanahan, D. An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J Clin Invest 2004, 114, 623-633.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 623-633
-
-
Giraudo, E.1
Inoue, M.2
Hanahan, D.3
-
8
-
-
10444274954
-
Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines
-
Matsumoto, S.; Kimura, S.; Segawa, H.; Kuroda, J.; Yuasa, T.; Sato, K.; Nogawa, M.; Tanaka, F.; Maekawa, T.; Wada, H. Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines. Lung Cancer 2005, 47, 31-39.
-
(2005)
Lung Cancer
, vol.47
, pp. 31-39
-
-
Matsumoto, S.1
Kimura, S.2
Segawa, H.3
Kuroda, J.4
Yuasa, T.5
Sato, K.6
Nogawa, M.7
Tanaka, F.8
Maekawa, T.9
Wada, H.10
-
9
-
-
28044467108
-
Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice
-
Ory, B.; Heymann, M. F.; Kamijo, A.; Gouin, F.; Heymann, D.; Redini, F. Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice. Cancer 2005, 104, 2522-2529.
-
(2005)
Cancer
, vol.104
, pp. 2522-2529
-
-
Ory, B.1
Heymann, M.F.2
Kamijo, A.3
Gouin, F.4
Heymann, D.5
Redini, F.6
-
10
-
-
33646751237
-
Bisphosphonates inhibit the growth of mesothelioma cells in vitro and in vivo
-
Wakchoure, S.; Merrell, M. A.; Aldrich, W.; Millender-Swain, T.; Harris, K. W.; Triozzi, P.; Selander, K. S. Bisphosphonates inhibit the growth of mesothelioma cells in vitro and in vivo. Clin Cancer Res 2006, 12, 2862-2868.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 2862-2868
-
-
Wakchoure, S.1
Merrell, M.A.2
Aldrich, W.3
Millender-Swain, T.4
Harris, K.W.5
Triozzi, P.6
Selander, K.S.7
-
11
-
-
37049006066
-
Amino-bisphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
-
Melani, C.; Sangaletti, S.; Barazzetta, F. M.; Werb, Z.; Colombo, M. P. Amino-bisphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res 2007, 67, 11438-11446.
-
(2007)
Cancer Res.
, vol.67
, pp. 11438-11446
-
-
Melani, C.1
Sangaletti, S.2
Barazzetta, F.M.3
Werb, Z.4
Colombo, M.P.5
-
12
-
-
46349091155
-
Zoledronic acid is effective against experimental malignant pleural effusion
-
Stathopoulos, G. T.; Moschos, C.; Loutrari, H.; Kollintza, A.; Psallidas, I.; Karabela, S.; Magkouta, S.; Zhou, Z.; Papiris, S. A.; Roussos, C.; Kalomenidis, I. Zoledronic acid is effective against experimental malignant pleural effusion. Am J Respir Crit Care Med 2008, 178, 50-59.
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, pp. 50-59
-
-
Stathopoulos, G.T.1
Moschos, C.2
Loutrari, H.3
Kollintza, A.4
Psallidas, I.5
Karabela, S.6
Magkouta, S.7
Zhou, Z.8
Papiris, S.A.9
Roussos, C.10
Kalomenidis, I.11
-
13
-
-
45949099277
-
The bisphosphonate, zoledronic acid reduces experimental neuroblastoma growth by interfering with tumor angiogenesis
-
Bäckman, U.; Svensson, A.; Christofferson, R. H.; Azarbayjani, F. The bisphosphonate, zoledronic acid reduces experimental neuroblastoma growth by interfering with tumor angiogenesis. Anticancer Res 2008, 28, 1551-1557.
-
(2008)
Anticancer Res.
, vol.28
, pp. 1551-1557
-
-
Bäckman, U.1
Svensson, A.2
Christofferson, R.H.3
Azarbayjani, F.4
-
14
-
-
38749122501
-
Zoledronic acid is unable to induce apoptosis, but slows tumor growth and prolongs survival for non-small-cell lung cancers
-
Li, Y. Y.; Chang, J. W. C.; Chou, W. C.; Liaw, C. C.; Wang, H. M.; Huang, J. S.; Wang, C. H.; Yeh, K. Y. Zoledronic acid is unable to induce apoptosis, but slows tumor growth and prolongs survival for non-small-cell lung cancers. Lung Cancer 2008, 59, 180-191.
-
(2008)
Lung Cancer
, vol.59
, pp. 180-191
-
-
Li, Y.Y.1
Chang, J.W.C.2
Chou, W.C.3
Liaw, C.C.4
Wang, H.M.5
Huang, J.S.6
Wang, C.H.7
Yeh, K.Y.8
-
15
-
-
51049114468
-
Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer
-
Ottewell, P. D.; Mönkkönen, H.; Jones, M.; Lefley, D. V.; Coleman, R. E.; Holen, I. Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer. J Natl Cancer Inst 2008, 100, 1167-1178.
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1167-1178
-
-
Ottewell, P.D.1
Mönkkönen, H.2
Jones, M.3
Lefley, D.V.4
Coleman, R.E.5
Holen, I.6
-
16
-
-
54549107866
-
Synergistic inhibitory activity of zoledronate and paclitaxel on bone metastasis in nude mice
-
Lu, S.; Zhang, J.; Zhou, Z.; Liao, M. L.; He, W. Z.; Zhou, X. Y.; Li, Z. M.; Xiang, J. Q.; Wang, J. J.; Chen, H. Q. Synergistic inhibitory activity of zoledronate and paclitaxel on bone metastasis in nude mice. Oncol Rep 2008, 20, 581-587.
-
(2008)
Oncol. Rep.
, vol.20
, pp. 581-587
-
-
Lu, S.1
Zhang, J.2
Zhou, Z.3
Liao, M.L.4
He, W.Z.5
Zhou, X.Y.6
Li, Z.M.7
Xiang, J.Q.8
Wang, J.J.9
Chen, H.Q.10
-
17
-
-
63449098528
-
Bisphosphonate zoledronic acid enhances the inhibitory effects of gefitinib on EGFR-mutated non-small cell lung carcinoma cells
-
Chang, J. W. C.; Hsieh, J. J.; Shen, Y. C.; Yeh, K. Y.; Wang, C. H.; Li, Y. Y.; Hsu, T. Bisphosphonate zoledronic acid enhances the inhibitory effects of gefitinib on EGFR-mutated non-small cell lung carcinoma cells. Cancer Lett 2009, 278, 17-26.
-
(2009)
Cancer Lett.
, vol.278
, pp. 17-26
-
-
Chang, J.W.C.1
Hsieh, J.J.2
Shen, Y.C.3
Yeh, K.Y.4
Wang, C.H.5
Li, Y.Y.6
Hsu, T.7
-
18
-
-
78650051896
-
Zoledronic acid repolarizes tumor-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway
-
Oct. 10 Epub ahead of print
-
Coscia, M.; Quaglino, E.; Iezzi, M.; Curcio, C.; Pantaleoni, F.; Riganti, C.; Holen, I.; Mönkkönen, H.; Boccadoro, M.; Forni, G.; Musiani, P.; Bosia, A.; Cavallo, F.; Massaia, M. Zoledronic acid repolarizes tumor-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. J Cell Mol Med. 2009 Oct. 10 [Epub ahead of print]
-
(2009)
J. Cell. Mol. Med.
-
-
Coscia, M.1
Quaglino, E.2
Iezzi, M.3
Curcio, C.4
Pantaleoni, F.5
Riganti, C.6
Holen, I.7
Mönkkönen, H.8
Boccadoro, M.9
Forni, G.10
Musiani, P.11
Bosia, A.12
Cavallo, F.13
Massaia, M.14
-
19
-
-
73549086519
-
Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model
-
Ottewell, P. D.; Lefley, D. V.; Cross, S. S.; Evans, C. A.; Coleman, R. E.; Holen, I. Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model. Int J Cancer 2009, 126, 522-532.
-
(2009)
Int. J. Cancer
, vol.126
, pp. 522-532
-
-
Ottewell, P.D.1
Lefley, D.V.2
Cross, S.S.3
Evans, C.A.4
Coleman, R.E.5
Holen, I.6
-
20
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy, G. R. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002, 2, 584-593.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
21
-
-
68549096058
-
The impact of zoledronic aid therapy in survival of lung cancer patients with bone metastasis
-
Zarogoulidis, K.; Boutsikou, E.; Zarogoulidis, P.; Eleftheriadou, E.; Kontakiotis, T.; Lithoxopoulou, H.; Tzanakakis, G.; Kanakis, I.; Karamanos, N. K. The impact of zoledronic aid therapy in survival of lung cancer patients with bone metastasis. Int J Cancer 2009, 125, 1705-1709.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 1705-1709
-
-
Zarogoulidis, K.1
Boutsikou, E.2
Zarogoulidis, P.3
Eleftheriadou, E.4
Kontakiotis, T.5
Lithoxopoulou, H.6
Tzanakakis, G.7
Kanakis, I.8
Karamanos, N.K.9
-
22
-
-
36248938315
-
Antitumor effect of zoledronic acid in previously untreated patients with multiple myeloma
-
Avilés, A.; Nambo, M. J.; Neri, N.; Castañeda, C.; Cleto, S.; Huerta-Guzmán, J. Antitumor effect of zoledronic acid in previously untreated patients with multiple myeloma. Med Oncol 2007, 24, 227-230.
-
(2007)
Med. Oncol.
, vol.24
, pp. 227-230
-
-
Avilés, A.1
Nambo, M.J.2
Neri, N.3
Castañeda, C.4
Cleto, S.5
Huerta-Guzmán, J.6
-
23
-
-
60549097419
-
ABCSG-12 Trial Investigators; Marth, C. Endocrine therapy plus zoledronic acid in premenopausal breast cancer
-
Gnant, M.; Mlineritsch, B.; Schippinger, W.; Luschin-Ebengreuth, G.; Pöstlberger, S.; Menzel, C.; Jakesz, R.; Seifert, M.; Hubalek, M.; Bjelic-Radisic, V.; Samonigg, H.; Tausch, C.; Eidtmann, H.; Steger, G.; Kwasny, W.; Dubsky, P.; Fridrik, M.; Fitzal, F.; Stierer, M.; Rücklinger, E.; Greil, R. ABCSG-12 Trial Investigators; Marth, C. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N Engl J Med 2009, 360, 679-691.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 679-691
-
-
Gnant, M.1
Mlineritsch, B.2
Schippinger, W.3
Luschin-Ebengreuth, G.4
Pöstlberger, S.5
Menzel, C.6
Jakesz, R.7
Seifert, M.8
Hubalek, M.9
Bjelic-Radisic, V.10
Samonigg, H.11
Tausch, C.12
Eidtmann, H.13
Steger, G.14
Kwasny, W.15
Dubsky, P.16
Fridrik, M.17
Fitzal, F.18
Stierer, M.19
Rücklinger, E.20
Greil, R.21
more..
-
24
-
-
0037038355
-
Development and validation of a highly sensitive RIA for zoledronic acid, a new potent heterocyclic bisphosphonate, in human serum, plasma and urine
-
Legay, F.; Gauron, S.; Deckert, F.; Gosset, G.; Pfaar, U.; Ravera, C.; Wiegand, H.; Schran, H. Development and validation of a highly sensitive RIA for zoledronic acid, a new potent heterocyclic bisphosphonate, in human serum, plasma and urine. J Pharm Biomed Anal 2002, 30, 897-911.
-
(2002)
J. Pharm. Biomed. Anal.
, vol.30
, pp. 897-911
-
-
Legay, F.1
Gauron, S.2
Deckert, F.3
Gosset, G.4
Pfaar, U.5
Ravera, C.6
Wiegand, H.7
Schran, H.8
-
25
-
-
33646080124
-
Relative binding affinities of bisphosphonates for human bone and relationship to antiresorptive efficacy
-
Leu, C. T.; Luegmayr, E.; Freedman, L. P.; Rodan, G. A.; Reszka, A. A. Relative binding affinities of bisphosphonates for human bone and relationship to antiresorptive efficacy. Bone 2006, 38, 628-36.
-
(2006)
Bone
, vol.38
, pp. 628-636
-
-
Leu, C.T.1
Luegmayr, E.2
Freedman, L.P.3
Rodan, G.A.4
Reszka, A.A.5
-
26
-
-
18644373689
-
Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases
-
Chen, T.; Berenson, J.; Vescio, R.; Swift, R.; Gilchick, A.; Goodin, S.; LoRusso, P.; Ma, P.; Ravera, C.; Deckert, F.; Schran, H.; Seaman, J.; Skerjanec, A. Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases. J Clin Pharmacol 2002, 42, 1228-1236.
-
(2002)
J. Clin. Pharmacol.
, vol.42
, pp. 1228-1236
-
-
Chen, T.1
Berenson, J.2
Vescio, R.3
Swift, R.4
Gilchick, A.5
Goodin, S.6
LoRusso, P.7
Ma, P.8
Ravera, C.9
Deckert, F.10
Schran, H.11
Seaman, J.12
Skerjanec, A.13
-
27
-
-
52949134055
-
Biodistribution and plasma protein binding of zoledronic acid
-
Weiss, H. M.; Pfaar, U.; Schweitzer, A.; Wiegand, H.; Skerjanec, A.; Schran, H. Biodistribution and plasma protein binding of zoledronic acid. Drug Metab Dispos 2008, 36, 2043-2049.
-
(2008)
Drug Metab. Dispos
, vol.36
, pp. 2043-2049
-
-
Weiss, H.M.1
Pfaar, U.2
Schweitzer, A.3
Wiegand, H.4
Skerjanec, A.5
Schran, H.6
-
28
-
-
33646089442
-
Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite
-
Nancollas, G. H.; Tang, R.; Phipps, R. J.; Henneman, Z.; Gulde, S.; Wu, W.; Mangood, A.; Russell, R. G.; Ebetino, F. H. Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite. Bone 2006, 38, 617-627.
-
(2006)
Bone
, vol.38
, pp. 617-627
-
-
Nancollas, G.H.1
Tang, R.2
Phipps, R.J.3
Henneman, Z.4
Gulde, S.5
Wu, W.6
Mangood, A.7
Russell, R.G.8
Ebetino, F.H.9
-
29
-
-
58149086028
-
Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP
-
Roelofs, A. J.; Jauhiainen, M.; Mönkkönen, H.; Rogers, M. J.; Mönkkönen, J.; Thompson, K. Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP. Br J Haematol. 2009, 144, 245-250.
-
(2009)
Br. J. Haematol.
, vol.144
, pp. 245-250
-
-
Roelofs, A.J.1
Jauhiainen, M.2
Mönkkönen, H.3
Rogers, M.J.4
Mönkkönen, J.5
Thompson, K.6
-
30
-
-
33645814413
-
Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis
-
Thompson, K.; Rogers, M. J.; Coxon, F. P.; Crockett, J. C. Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis. Mol Pharmacol 2006, 69, 1624-1632.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 1624-1632
-
-
Thompson, K.1
Rogers, M.J.2
Coxon, F.P.3
Crockett, J.C.4
-
31
-
-
46949100735
-
Exploring the anti-tumour activity of bisphosphonates in early breast cancer
-
Winter, M. C.; Holen, I.; Coleman, R. E. Exploring the anti-tumour activity of bisphosphonates in early breast cancer. Cancer Treat Rev 2008, 34, 453-475.
-
(2008)
Cancer Treat Rev.
, vol.34
, pp. 453-475
-
-
Winter, M.C.1
Holen, I.2
Coleman, R.E.3
-
32
-
-
0037455013
-
Human T cell receptor gamma delta cells recognize endogenous mevalonate metabolites in tumor cells
-
Gober, H. J.; Kistowska, M.; Angman, L.; Jenö, P.; Mori, L.; De Libero, G. Human T cell receptor gamma delta cells recognize endogenous mevalonate metabolites in tumor cells. J Exp Med 2003, 197, 163-168.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 163-168
-
-
Gober, H.J.1
Kistowska, M.2
Angman, L.3
Jenö, P.4
Mori, L.5
De Libero, G.6
-
33
-
-
36749030025
-
Gamma delta T cells and dendritic cells: Close partners and biological adjuvants for new therapies
-
Martino, A.; Poccia, F. Gamma delta T cells and dendritic cells: close partners and biological adjuvants for new therapies. Curr Mol Med 2007, 7, 658-673.
-
(2007)
Curr. Mol. Med.
, vol.7
, pp. 658-673
-
-
Martino, A.1
Poccia, F.2
-
34
-
-
77958010352
-
Zoledronic acid-induced IPP/Apppl (phosphoantigen) accumulation in human breast cancer cells correlates with Vgamma9Vdelta2 T-cell mediated cancer cell death in vitro and in vivo [abstract S9]
-
Benzaid, I.; Mönkkönen, H.; Stresing, V.; Bonnelye, E.; Green, J.; Mönkkönen, J.; Touraine, J.; Clézardin, P. Zoledronic acid-induced IPP/Apppl (phosphoantigen) accumulation in human breast cancer cells correlates with Vgamma9Vdelta2 T-cell mediated cancer cell death in vitro and in vivo [abstract S9]. Bone 2010, 47: S266-S267.
-
(2010)
Bone
, vol.47
-
-
Benzaid, I.1
Mönkkönen, H.2
Stresing, V.3
Bonnelye, E.4
Green, J.5
Mönkkönen, J.6
Touraine, J.7
Clézardin, P.8
-
35
-
-
69749110704
-
Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro
-
Räikkönen, J.; Crockett, J. C.; Rogers, M. J.; Mönkkönen, H.; Auriola, S.; Mönkkönen, J. Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro. Br J Pharmacol 2009, 157, 427-435.
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 427-435
-
-
Räikkönen, J.1
Crockett, J.C.2
Rogers, M.J.3
Mönkkönen, H.4
Auriola, S.5
Mönkkönen, J.6
-
36
-
-
34648828862
-
Bisphosphonates in cancer therapy
-
Stresing, V.; Daubiné, F.; Benzaid, I.; Mönkkönen, H.; Clézardin, P. Bisphosphonates in cancer therapy. Cancer Lett 2007, 257, 16-35.
-
(2007)
Cancer Lett.
, vol.257
, pp. 16-35
-
-
Stresing, V.1
Daubiné, F.2
Benzaid, I.3
Mönkkönen, H.4
Clézardin, P.5
-
37
-
-
0035146537
-
Structure-activity relationships for inhibition of farnesyl disphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates
-
Dunford, J. E.; Thompson, K.; Coxon, F. P.; Luckman, S. P.; Hahn, F. M.; Poulter, C. D.; Ebetino, F. H.; Rogers, M. J. Structure-activity relationships for inhibition of farnesyl disphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. J Pharmacol Exp Ther 2001, 296, 235-242.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 235-242
-
-
Dunford, J.E.1
Thompson, K.2
Coxon, F.P.3
Luckman, S.P.4
Hahn, F.M.5
Poulter, C.D.6
Ebetino, F.H.7
Rogers, M.J.8
-
38
-
-
41849123834
-
Structureactivity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: Time-dependent inhibition of human farnesyl pyrophosphate synthase
-
Dunford, J. E.; Kwaasi, A. A.; Rogers, M. J.; Barnett, B. L.; Ebetino, F. H.; Russell, R. G.; Oppermann, U.; Kavanagh, K. L. Structureactivity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase. J Med Chem 2008, 51, 2187-2195.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 2187-2195
-
-
Dunford, J.E.1
Kwaasi, A.A.2
Rogers, M.J.3
Barnett, B.L.4
Ebetino, F.H.5
Russell, R.G.6
Oppermann, U.7
Kavanagh, K.L.8
-
39
-
-
34547231214
-
Bisphosphonates target multiple sites in both cis-and trans-prenyltransferases
-
Guo, R. T.; Cao, R.; Liang, P. H.; Ko, T. P.; Chang, T. H.; Hudock, M. P.; Jeng, W. Y.; Chen, C. K.; Zhang, Y.; Song, Y.; Kuo, C. J.; Yin, F.; Oldfield, E.; Wang, A. H. Bisphosphonates target multiple sites in both cis-and trans-prenyltransferases. Proc Natl Acad Sci U S A 2007, 104, 10022-10027.
-
(2007)
Proc. Natl. Acad. Sci. U S A
, vol.104
, pp. 10022-10027
-
-
Guo, R.T.1
Cao, R.2
Liang, P.H.3
Ko, T.P.4
Chang, T.H.5
Hudock, M.P.6
Jeng, W.Y.7
Chen, C.K.8
Zhang, Y.9
Song, Y.10
Kuo, C.J.11
Yin, F.12
Oldfield, E.13
Wang, A.H.14
-
40
-
-
76249119723
-
Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection
-
Bivi, N.; Romanello, M.; Harrison, R.; Clarke, I.; Hoyle, D. C.; Moro, L.; Ortolani, F.; Bonetti, A.; Quadrifoglio, F.; Tell, G.; Delneri, D. Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection. Genome Biol 2009, 10, R93.
-
(2009)
Genome Biol.
, vol.10
-
-
Bivi, N.1
Romanello, M.2
Harrison, R.3
Clarke, I.4
Hoyle, D.C.5
Moro, L.6
Ortolani, F.7
Bonetti, A.8
Quadrifoglio, F.9
Tell, G.10
Delneri, D.11
-
41
-
-
47949090189
-
Bisphosphonateinduced ATP analog formation and its effect on inhibition of cancer cell growth
-
Mönkkönen, H.; Kuokkanen, J.; Holen, I.; Evans, A.; Lefley, D. V.; Jauhiainen, M.; Auriola, S.; Mönkkönen, J. Bisphosphonateinduced ATP analog formation and its effect on inhibition of cancer cell growth. Anticancer Drugs 2008, 19, 391-399.
-
(2008)
Anticancer Drugs
, vol.19
, pp. 391-399
-
-
Mönkkönen, H.1
Kuokkanen, J.2
Holen, I.3
Evans, A.4
Lefley, D.V.5
Jauhiainen, M.6
Auriola, S.7
Mönkkönen, J.8
-
42
-
-
0033783227
-
Bisphosphonates induce breast cancer cell death in vitro
-
Fromigue, O.; Lagneaux, L.; Body, J. J. Bisphosphonates induce breast cancer cell death in vitro. J Bone Miner Res 2000, 15, 2211-2221.
-
(2000)
J. Bone Miner. Res.
, vol.15
, pp. 2211-2221
-
-
Fromigue, O.1
Lagneaux, L.2
Body, J.J.3
-
43
-
-
0034107048
-
Bisphosphonates induce apoptosis in human breast cancer cell lines
-
Senaratne, S. G.; Pirianov, G.; Mansi, J. L.; Arnett, T. R.; Colston, K. W. Bisphosphonates induce apoptosis in human breast cancer cell lines. Br J Cancer 2000, 82, 1459-1468.
-
(2000)
Br. J. Cancer
, vol.82
, pp. 1459-1468
-
-
Senaratne, S.G.1
Pirianov, G.2
Mansi, J.L.3
Arnett, T.R.4
Colston, K.W.5
-
44
-
-
0035917560
-
The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: Evidence for synergy with paclitaxel
-
Jagdev, S. P.; Coleman, R. E.; Shipman, C. M.; Rostami, H. A.; Croucher, P. I. The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel. Br J Cancer 2001, 84, 1126-1134.
-
(2001)
Br. J. Cancer
, vol.84
, pp. 1126-1134
-
-
Jagdev, S.P.1
Coleman, R.E.2
Shipman, C.M.3
Rostami, H.A.4
Croucher, P.I.5
-
45
-
-
33845659966
-
Differential effects of bisphosphonates on breast cancer cell lines
-
Verdijk, R.; Franke, H. R.; Wolbers, F.; Vermes, I. Differential effects of bisphosphonates on breast cancer cell lines. Cancer Lett 2007, 246, 308-312.
-
(2007)
Cancer Lett.
, vol.246
, pp. 308-312
-
-
Verdijk, R.1
Franke, H.R.2
Wolbers, F.3
Vermes, I.4
-
46
-
-
61349126550
-
Zoledronic acid induces caspase-dependent apoptosis in renal cancer cell lines
-
Ullén, A.; Schwarz, S.; Lennartsson, L.; Kalkner, K. M.; Sandstrom, P.; Costa, F.; Lennernas, B.; Linder, S.; Nilsson, S. Zoledronic acid induces caspase-dependent apoptosis in renal cancer cell lines. Scand J Urol Nephrol 2009, 43, 98-103.
-
(2009)
Scand. J. Urol. Nephrol.
, vol.43
, pp. 98-103
-
-
Ullén, A.1
Schwarz, S.2
Lennartsson, L.3
Kalkner, K.M.4
Sandstrom, P.5
Costa, F.6
Lennernas, B.7
Linder, S.8
Nilsson, S.9
-
47
-
-
58749100624
-
Docetaxel/zoledronic acid combination triggers apoptosis synergistically through downregulating antiapoptotic Bcl-2 protein level in hormone-refractory prostate cancer cells
-
Karabulut, B.; Erten, C.; Gul, M. K.; Cengiz, E.; Karaca, B.; Kucukzeybek, Y.; Gorumlu, G.; Atmaca, H.; Uzunoglu, S.; Sanli, U. A.; Baran, Y.; Uslu, R. Docetaxel/zoledronic acid combination triggers apoptosis synergistically through downregulating antiapoptotic Bcl-2 protein level in hormone-refractory prostate cancer cells. Cell Biol Int 2009, 33, 239-246.
-
(2009)
Cell. Biol. Int.
, vol.33
, pp. 239-246
-
-
Karabulut, B.1
Erten, C.2
Gul, M.K.3
Cengiz, E.4
Karaca, B.5
Kucukzeybek, Y.6
Gorumlu, G.7
Atmaca, H.8
Uzunoglu, S.9
Sanli, U.A.10
Baran, Y.11
Uslu, R.12
-
48
-
-
12544258728
-
Zoledronic acid inhibits adhesion of breast cancer cells to protein matrices in a caspase dependent manner
-
abstr
-
Pickering, L. M.; Macdonald, C. D.; Coxon, J. P.; Mansi, J. L.; Colston, K. W. Zoledronic acid inhibits adhesion of breast cancer cells to protein matrices in a caspase dependent manner. Bone 2004, 34 (suppl 1, abstr 38), S68-S69
-
(2004)
Bone
, vol.34
, Issue.1-38 SUPPL.
-
-
Pickering, L.M.1
Macdonald, C.D.2
Coxon, J.P.3
Mansi, J.L.4
Colston, K.W.5
-
49
-
-
77957982537
-
Prevention of breast cancer cell adhesion to bone in vitro by bisphosphonates is mediated by their inhibitory effect on protein prenylation
-
abstr 45
-
Garrioch, S.; Roelofs, A. J.; Ebetino, F. H.; Rogers, M. J. Prevention of breast cancer cell adhesion to bone in vitro by bisphosphonates is mediated by their inhibitory effect on protein prenylation. Bone 2006, 38 (3 suppl 1, abstr 45), S59-S60.
-
(2006)
Bone
, vol.38
, Issue.1-3 SUPPL.
-
-
Garrioch, S.1
Roelofs, A.J.2
Ebetino, F.H.3
Rogers, M.J.4
-
50
-
-
0034214362
-
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
-
Boissier, S.; Ferreras, M.; Peyruchaud, O.; Magnetto, S.; Ebetino, F. H.; Colombel, M.; Delmas, P.; Delaissé, J. M.; Clézardin, P. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. Cancer Res 2000, 60, 2949-2954.
-
(2000)
Cancer Res.
, vol.60
, pp. 2949-2954
-
-
Boissier, S.1
Ferreras, M.2
Peyruchaud, O.3
Magnetto, S.4
Ebetino, F.H.5
Colombel, M.6
Delmas, P.7
Delaissé, J.M.8
Clézardin, P.9
-
51
-
-
58149296145
-
Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastases in a murine osteosarcoma model
-
Koto, K.; Horie, N.; Kumura, S.; Murata, H.; Sakabe, T.; Matsui, T.; Watanabe, M.; Adachi, S.; Maekawa, T.; Fushiki, S.; Kubo, T. Clinically relevant dose of zoledronic acid inhibits spontaneous lung metastases in a murine osteosarcoma model. Cancer Lett 2009, 274, 271-278.
-
(2009)
Cancer Lett.
, vol.274
, pp. 271-278
-
-
Koto, K.1
Horie, N.2
Kumura, S.3
Murata, H.4
Sakabe, T.5
Matsui, T.6
Watanabe, M.7
Adachi, S.8
Maekawa, T.9
Fushiki, S.10
Kubo, T.11
-
52
-
-
0038792653
-
New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by duel RhoA-dependent and-independent effects
-
Denoyelle, C.; Hong, L.; Vannier, J.-P.; Soria, J.; Soria, C. New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by duel RhoA-dependent and-independent effects. Br J Cancer 2003, 88, 1631-1640.
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1631-1640
-
-
Denoyelle, C.1
Hong, L.2
Vannier, J.-P.3
Soria, J.4
Soria, C.5
-
53
-
-
0036721078
-
Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid
-
Wood, J.; Bonjean, K.; Ruetz, S.; Bellahcène, A.; Devy, L.; Foidart, J. M.; Castronovo, V.; Green, J. R. Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid. J Pharmacol Exp Ther 2002, 302, 1055-1061.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 1055-1061
-
-
Wood, J.1
Bonjean, K.2
Ruetz, S.3
Bellahcène, A.4
Devy, L.5
Foidart, J.M.6
Castronovo, V.7
Green, J.R.8
-
54
-
-
57149098821
-
Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation
-
Yamada, J.; Tsuno, N. H.; Kitayama, J.; Tsuchiya, T.; Yoneyama, S.; Asakage, M.; Okaji, Y.; Shuno, Y.; Nishikawa, T.; Tanaka, J.; Takahashi, K.; Nagawa, H. Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation. J Surg Res 2009, 151, 115-120.
-
(2009)
J. Surg. Res.
, vol.151
, pp. 115-120
-
-
Yamada, J.1
Tsuno, N.H.2
Kitayama, J.3
Tsuchiya, T.4
Yoneyama, S.5
Asakage, M.6
Okaji, Y.7
Shuno, Y.8
Nishikawa, T.9
Tanaka, J.10
Takahashi, K.11
Nagawa, H.12
-
55
-
-
33845524204
-
Role of tumor-associated macrophages in tumor progression and invasion
-
Mantovani, A.; Schioppa, T.; Porta, C.; Allavena, P.; Sica, A. Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev 2006, 25, 315-322.
-
(2006)
Cancer Metastasis Rev.
, vol.25
, pp. 315-322
-
-
Mantovani, A.1
Schioppa, T.2
Porta, C.3
Allavena, P.4
Sica, A.5
-
56
-
-
77955066398
-
Activation of gammadelta T cells by bisphosphonates
-
Thompson, K.; Roelofs, A. J.; Jauhiainen, M.; Mönkkönen, H.; Mönkkönen, J.; Rogers, M. J. Activation of gammadelta T cells by bisphosphonates. Adv Exp Med Biol 2010, 658, 11-20.
-
(2010)
Adv. Exp. Med. Biol.
, vol.658
, pp. 11-20
-
-
Thompson, K.1
Roelofs, A.J.2
Jauhiainen, M.3
Mönkkönen, H.4
Mönkkönen, J.5
Rogers, M.J.6
-
57
-
-
35348839555
-
Zoledronic acid-a multiplicity of anti-cancer action
-
Yuasa, T.; Kimura, S.; Ashihara, E.; Habuchi, T.; Maekawa, T. Zoledronic acid-a multiplicity of anti-cancer action. Curr Med Chem 2007, 14, 2126-2135.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 2126-2135
-
-
Yuasa, T.1
Kimura, S.2
Ashihara, E.3
Habuchi, T.4
Maekawa, T.5
-
58
-
-
1642526540
-
Statins prevent bisphosphonateinduced gamma, delta-T-cell proliferation and activation in vitro
-
Thompson, K.; Rogers, M. J. Statins prevent bisphosphonateinduced gamma, delta-T-cell proliferation and activation in vitro. J Bone Miner Res 2004, 19, 278-288.
-
(2004)
J. Bone Miner. Res.
, vol.19
, pp. 278-288
-
-
Thompson, K.1
Rogers, M.J.2
-
59
-
-
0141567513
-
Induction of gamma, delta T-lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo
-
Dieli, F.; Gebbia, N.; Poccia, F.; Caccamo, N.; Montesano, C.; Fulfaro, F.; Arcara, C.; Valerio, M. R.; Meraviglia, S.; Di Sano, C.; Sireci, G.; Salerno, A. Induction of gamma, delta T-lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo. Blood 2003, 102, 2310-2311.
-
(2003)
Blood
, vol.102
, pp. 2310-2311
-
-
Dieli, F.1
Gebbia, N.2
Poccia, F.3
Caccamo, N.4
Montesano, C.5
Fulfaro, F.6
Arcara, C.7
Valerio, M.R.8
Meraviglia, S.9
Di Sano, C.10
Sireci, G.11
Salerno, A.12
-
60
-
-
70449720530
-
Modulation of innate immunity by IL-18
-
Li, W.; Yamamoto, H.; Kubo, S.; Okamura, H. Modulation of innate immunity by IL-18. J Reprod Immunol 2009, 83, 101-105.
-
(2009)
J. Reprod. Immunol.
, vol.83
, pp. 101-105
-
-
Li, W.1
Yamamoto, H.2
Kubo, S.3
Okamura, H.4
-
61
-
-
20444445149
-
Cytotoxic effects of gamma, delta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy
-
Sato, K.; Kimura, S.; Segawa, H.; Yokota, A.; Matsumoto, S.; Kuroda, J.; Nogawa, M.; Yuasa, T.; Kiyono, Y.; Wada, H.; Maekawa, T. Cytotoxic effects of gamma, delta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy. Int J Cancer 2005, 116, 94-99.
-
(2005)
Int. J. Cancer
, vol.116
, pp. 94-99
-
-
Sato, K.1
Kimura, S.2
Segawa, H.3
Yokota, A.4
Matsumoto, S.5
Kuroda, J.6
Nogawa, M.7
Yuasa, T.8
Kiyono, Y.9
Wada, H.10
Maekawa, T.11
-
62
-
-
41949092083
-
Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells
-
Coxon, F. P.; Thompson, K.; Roelofs, A. J.; Ebetino, F. H.; Rogers, M. J. Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells. Bone 2008, 42, 848-860.
-
(2008)
Bone
, vol.42
, pp. 848-860
-
-
Coxon, F.P.1
Thompson, K.2
Roelofs, A.J.3
Ebetino, F.H.4
Rogers, M.J.5
-
63
-
-
34249338002
-
Tumor-associated macrophage: Its role in cancer invasion and metastasis
-
Shih, J. Y.; Yuan, A.; Chen, J. J. W.; Yang, P. C. Tumor-associated macrophage: its role in cancer invasion and metastasis. J Cancer Mol 2006, 2, 101-106.
-
(2006)
J. Cancer Mol.
, vol.2
, pp. 101-106
-
-
Shih, J.Y.1
Yuan, A.2
Chen, J.J.W.3
Yang, P.C.4
-
64
-
-
33847771427
-
Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis
-
Daubiné, F.; Le Gall, C.; Gasser, J.; Green, J.; Clézardin, P. Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis. J Natl Cancer Inst 2007, 99, 322-330.
-
(2007)
J. Natl. Cancer Inst.
, vol.99
, pp. 322-330
-
-
Daubiné, F.1
Gall, C.2
Gasser, J.3
Green, J.4
Clézardin, P.5
-
65
-
-
11144254409
-
Sequence-and schedule-dependent enhancement of zoledronic acid induced by apoptosis by doxorubicin in breast and prostate cancer cells
-
Neville-Webbe, H. L.; Rostami-Hodjegan, A.; Evans, C. A.; Coleman, R. E.; Holen, I. Sequence-and schedule-dependent enhancement of zoledronic acid induced by apoptosis by doxorubicin in breast and prostate cancer cells. Int J Cancer 2005, 113, 364-371.
-
(2005)
Int. J. Cancer
, vol.113
, pp. 364-371
-
-
Neville-Webbe, H.L.1
Rostami-Hodjegan, A.2
Evans, C.A.3
Coleman, R.E.4
Holen, I.5
-
66
-
-
33646107396
-
Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro
-
Neville-Webbe, H. L.; Evans, C. A.; Coleman, R. E.; Holen, I. Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro. Tumor Biol 2006, 27, 92-103.
-
(2006)
Tumor Biol.
, vol.27
, pp. 92-103
-
-
Neville-Webbe, H.L.1
Evans, C.A.2
Coleman, R.E.3
Holen, I.4
-
67
-
-
77949541181
-
Combined effects of the bisphosphonate zoledronic acid and the aromatase inhibitor letrozole on breast cancer cells in vitro: Evidence of synergistic interaction
-
Neville-Webbe, H. L.; Coleman, R. E.; Holen, L. Combined effects of the bisphosphonate zoledronic acid and the aromatase inhibitor letrozole on breast cancer cells in vitro: evidence of synergistic interaction. Br J Cancer 2010, 102, 1010-1017.
-
(2010)
Br. J. Cancer
, vol.102
, pp. 1010-1017
-
-
Neville-Webbe, H.L.1
Coleman, R.E.2
Holen, L.3
-
68
-
-
77649178985
-
Increased anti-tumour effects of doxorubicin and zoledronic acid in prostate cancer cells in vitro: Supporting the benefits of combination therapy
-
Clyburn, R. D.; Reid, P.; Evans, C. A.; Lefley, D. V.; Holen, I. Increased anti-tumour effects of doxorubicin and zoledronic acid in prostate cancer cells in vitro: supporting the benefits of combination therapy. Cancer Chemother Pharmacol 2010, 65, 969-978.
-
(2010)
Cancer Chemother. Pharmacol.
, vol.65
, pp. 969-978
-
-
Clyburn, R.D.1
Reid, P.2
Evans, C.A.3
Lefley, D.V.4
Holen, I.5
-
69
-
-
0043075946
-
Effect of the combination of docetaxel, zoledronic acid, and a COX-2 inhibitor on the growth of human breast cancer cell lines
-
Witters, L. M.; Crispino, J.; Fraterrigo, T.; Green, J.; Lipton, A. Effect of the combination of docetaxel, zoledronic acid, and a COX-2 inhibitor on the growth of human breast cancer cell lines. Am J Clin Oncol 2003, 26, S92-S97.
-
(2003)
Am. J. Clin. Oncol.
, vol.26
-
-
Witters, L.M.1
Crispino, J.2
Fraterrigo, T.3
Green, J.4
Lipton, A.5
-
70
-
-
16544379650
-
Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/methotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid
-
Vogt, U.; Bielawski, K. P.; Bosse, U.; Schlotter, C. M. Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/ methotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid. Oncol Rep 2004, 12, 1109-1114.
-
(2004)
Oncol. Rep.
, vol.12
, pp. 1109-1114
-
-
Vogt, U.1
Bielawski, K.P.2
Bosse, U.3
Schlotter, C.M.4
-
71
-
-
29144521942
-
Zoledronic acid cooperates with a cyclooxygenase-2 inhibitor and gefitinib in inhibiting breast and prostate cancer
-
Melisi, D.; Caputo, R.; Damiano, V.; Bianco, R.; Veneziani, B. M.; Bianco, A. R.; De Placido, S.; Ciardiello, F.; Tortora, G. Zoledronic acid cooperates with a cyclooxygenase-2 inhibitor and gefitinib in inhibiting breast and prostate cancer. Endocr Relat Cancer 2005, 12, 1051-1058.
-
(2005)
Endocr Relat. Cancer
, vol.12
, pp. 1051-1058
-
-
Melisi, D.1
Caputo, R.2
Damiano, V.3
Bianco, R.4
Veneziani, B.M.5
Bianco, A.R.6
De Placido, S.7
Ciardiello, F.8
Tortora, G.9
-
72
-
-
70350234896
-
Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone
-
Ottewell, P. D.; Woodward, J. K.; Lefley, D. V.; Evans, C. A.; Coleman, R. E.; Holen, I. Anticancer mechanisms of doxorubicin and zoledronic acid in breast cancer tumor growth in bone. Mol Cancer Ther 2009, 8, 2821-2832.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2821-2832
-
-
Ottewell, P.D.1
Woodward, J.K.2
Lefley, D.V.3
Evans, C.A.4
Coleman, R.E.5
Holen, I.6
-
73
-
-
63549119635
-
Zoledronic acid-induced regression of multiple metastases at nonskeletal sites
-
Okamoto, K.; Tsurutani, J.; Terashima, M.; Okamoto, I.; Nakagawa, K. Zoledronic acid-induced regression of multiple metastases at nonskeletal sites. Ann Oncol 2009, 20796-797.
-
(2009)
Ann. Oncol.
, pp. 20796-20797
-
-
Okamoto, K.1
Tsurutani, J.2
Terashima, M.3
Okamoto, I.4
Nakagawa, K.5
-
74
-
-
67349188865
-
Regression of melanoma metastases following treatment with the n-bisphosphonate zoledronate and localised radiotherapy
-
Laggner, U.; Lopez, J. S.; Perera, G.; Warbey, V. S.; Sita-Lumsden, A.; O'Doherty, M. J.; Hayday, A.; Harries, M.; Nestle, F. O. Regression of melanoma metastases following treatment with the n-bisphosphonate zoledronate and localised radiotherapy. Clin Immunol 2009, 131, 367-373.
-
(2009)
Clin. Immunol.
, vol.131
, pp. 367-373
-
-
Laggner, U.1
Lopez, J.S.2
Perera, G.3
Warbey, V.S.4
Sita-Lumsden, A.5
O'Doherty, M.J.6
Hayday, A.7
Harries, M.8
Nestle, F.O.9
-
75
-
-
4043073394
-
Zoledronate-induced remission of actue panmyelosis with myelofibrosis
-
Español, I.; Romagosa, V.; Berlanga, J.; Domingo, A.; Losa, F.; Heras, L.; Janáriz, J. Zoledronate-induced remission of actue panmyelosis with myelofibrosis. Eur J Haematol 2004, 73, 215-218.
-
(2004)
Eur. J. Haematol.
, vol.73
, pp. 215-218
-
-
Español, I.1
Romagosa, V.2
Berlanga, J.3
Domingo, A.4
Losa, F.5
Heras, L.6
Janáriz, J.7
-
76
-
-
77954572691
-
Effect of zoledronate on persisting isolated tumour cells in patients with early breast cancer
-
Rack, B.; Jückstock, J.; Genss, E. M.; Schoberth, A.; Schindlbeck, C.; Strobl, B.; Heinrigs, M.; Rammael, G.; Zwingers, T.; Sommer, H.; Friese, K.; Janni, W. Effect of zoledronate on persisting isolated tumour cells in patients with early breast cancer. Anticancer Res 2010, 30(5):1807-1813.
-
(2010)
Anticancer Res.
, vol.30
, Issue.5
, pp. 1807-1813
-
-
Rack, B.1
Jückstock, J.2
Genss, E.M.3
Schoberth, A.4
Schindlbeck, C.5
Strobl, B.6
Heinrigs, M.7
Rammael, G.8
Zwingers, T.9
Sommer, H.10
Friese, K.11
Janni, W.12
-
77
-
-
77952305169
-
Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: An open label, randomised, phase 2 trial
-
Aft, R.; Naughton, M.; Trinkaus, K.; Watson, M.; Ylagan, L.; Chavez-MacGregor, M.; Zhai, J.; Kuo, S.; Shannon, W.; Diemer, K.; Hermann, V.; Dietz, J.; Ali, A.; Ellis, M.; Weiss, P.; Eberlein, T.; Ma, C.; Fracasso, P. M.; Zoberi, I.; Taylor, M.; Gillanders, W.; Pluard, T.; Mortimer, J.; Weilbaecher, K. Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial. Lancet Oncol 2010, 11(5):421-428.
-
(2010)
Lancet Oncol.
, vol.11
, Issue.5
, pp. 421-428
-
-
Aft, R.1
Naughton, M.2
Trinkaus, K.3
Watson, M.4
Ylagan, L.5
Chavez-MacGregor, M.6
Zhai, J.7
Kuo, S.8
Shannon, W.9
Diemer, K.10
Hermann, V.11
Dietz, J.12
Ali, A.13
Ellis, M.14
Weiss, P.15
Eberlein, T.16
Ma, C.17
Fracasso, P.M.18
Zoberi, I.19
Taylor, M.20
Gillanders, W.21
Pluard, T.22
Mortimer, J.23
Weilbaecher, K.24
more..
-
78
-
-
77958019182
-
Effect of adjuvant zoledronic acid (ZOL) on disseminated tumor cells (DTC) in the bone marrow (BM) of women with early-stage breast cancer (ESBC): Updated results [abstract 1002]
-
Presented at, Chicago, IL, June
-
Greenberg, S.; Park, J. W.; Melisko, M. E.; Goga, A.; Moasser, M. M.; Anderson, M.; Scott, J. H.; Petrillo, L. A.; Moore, D. H.; Rugo, H. S. Effect of adjuvant zoledronic acid (ZOL) on disseminated tumor cells (DTC) in the bone marrow (BM) of women with early-stage breast cancer (ESBC): Updated results [abstract 1002]. Presented at the 46th American Society of Clinical Oncology Meeting, Chicago, IL, June 4-8, 2010.
-
(2010)
The 46th American Society of Clinical Oncology Meeting
, pp. 4-8
-
-
Greenberg, S.1
Park, J.W.2
Melisko, M.E.3
Goga, A.4
Moasser, M.M.5
Anderson, M.6
Scott, J.H.7
Petrillo, L.A.8
Moore, D.H.9
Rugo, H.S.10
-
79
-
-
78649267109
-
Influence of zoledronic acid on disseminated tumor cells (DTC) in primary breast cancer patients
-
Presented at, San Antonio, TX, December, abstr 2048
-
Solomayer, E. F.; Gebauer, G.; Hirnle, P.; Janni, W.; Lück, H.-J.; Becker, S.; Huober, J.; Kraemer, B.; Wackwitz, B.; Fehm, T. Influence of zoledronic acid on disseminated tumor cells (DTC) in primary breast cancer patients. Presented at the 31st Annual San Antonio Breast Cancer Symposium, San Antonio, TX, December 10-14, 2008 (abstr 2048).
-
(2008)
The 31st Annual San Antonio Breast Cancer Symposium
, pp. 10-14
-
-
Solomayer, E.F.1
Gebauer, G.2
Hirnle, P.3
Janni, W.4
Lück, H.-J.5
Becker, S.6
Huober, J.7
Kraemer, B.8
Wackwitz, B.9
Fehm, T.10
-
80
-
-
67650032911
-
γδ T cell-based immunotherapy for patients with multiple myeloma
-
γδ T cell-based immunotherapy for patients with multiple myeloma. Exp Hematol 2009, 37, 956-968.
-
(2009)
Exp. Hematol
, vol.37
, pp. 956-968
-
-
Abe, Y.1
Muto, M.2
Nieda, M.3
Nakagawa, Y.4
Nicol, A.5
Kaneko, T.6
Goto, S.7
Yokokawa, K.8
Suzuki, K.9
-
81
-
-
54849441655
-
In vivo effects of zoledronic acid on peripheral gammadelta T lymphocytes in early breast cancer patients
-
Santini, D.; Martini, F.; Fratto, M. E.; Galluzzo, S.; Vincenzi, B.; Agrati, C.; Turchi, F.; Piacentini, P.; Rocci, L.; Manavalan, J. S.; Tonini, G.; Poccia, F. In vivo effects of zoledronic acid on peripheral gammadelta T lymphocytes in early breast cancer patients. Cancer Immunol Immunother 2009, 58, 31-38.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 31-38
-
-
Santini, D.1
Martini, F.2
Fratto, M.E.3
Galluzzo, S.4
Vincenzi, B.5
Agrati, C.6
Turchi, F.7
Piacentini, P.8
Rocci, L.9
Manavalan, J.S.10
Tonini, G.11
Poccia, F.12
-
82
-
-
77955560932
-
The effect of zoledronic acid on aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: The Z-FAST study 5-year final follow-up
-
Presented at, San Antonio, TX, December, abstr 4083
-
nd Annual San Antonio Breast Cancer Symposium, San Antonio, TX, December 10-13, 2009 (abstr 4083).
-
(2009)
nd Annual San Antonio Breast Cancer Symposium
, pp. 10-13
-
-
Brufsky, A.1
Harker, W.G.2
Beck, J.T.3
Carroll, R.4
Jin, L.5
Warsi, G.6
Argonza-Aviles, E.7
Ericson, S.8
Perez, E.A.9
-
83
-
-
67649804881
-
Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST study 36-month follow-up results
-
Brufsky, A.; Bosserman, L.; Caradonna, R.; Haley, B. B.; Jones, C. M.; Moore, H. C.; Jin, L.; Warsi, G. M.; Ericson, S. G.; Perez, E. A. Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST study 36-month follow-up results. Clin Breast Cancer 2009, 9, 77-85.
-
(2009)
Clin. Breast Cancer
, vol.9
, pp. 77-85
-
-
Brufsky, A.1
Bosserman, L.2
Caradonna, R.3
Haley, B.B.4
Jones, C.M.5
Moore, H.C.6
Jin, L.7
Warsi, G.M.8
Ericson, S.G.9
Perez, E.A.10
-
84
-
-
77954580167
-
Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study
-
May 5. Epub ahead of print
-
Eidtmann, H.; de Boer, R.; Bundred, N.; Llombart-Cussac, A.; Davidson, N.; Neven, P.; von Micnkwitz, G.; Miller, J.; Schenk, N.; Coleman, R. Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study. Ann Oncol 2010 May 5. [Epub ahead of print].
-
(2010)
Ann. Oncol.
-
-
Eidtmann, H.1
De Boer, R.2
Bundred, N.3
Llombart-Cussac, A.4
Davidson, N.5
Neven, P.6
Von Micnkwitz, G.7
Miller, J.8
Schenk, N.9
Coleman, R.10
-
85
-
-
45749089797
-
Integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole
-
DOI 10.1634/theoncologist.2007-0206
-
Brufsky, A.; Bundred, N.; Coleman, R.; Lambert-Falls, R.; Mena, R.; Hadji, P.; Jin, L.; Schenk, N.; Ericson, S.; Perez, E. A.; Z-FAST and ZO-FAST Study Groups. Integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole. Oncologist 2008, 13, 503-514. (Pubitemid 351872868)
-
(2008)
Oncologist
, vol.13
, Issue.5
, pp. 503-514
-
-
Brufsky, A.1
Bundred, N.2
Coleman, R.3
Lambert-Falls, R.4
Mena, R.5
Hadji, P.6
Jin, L.7
Schenk, N.8
Ericson, S.9
Perez, E.A.10
-
86
-
-
77953376340
-
The effect of zoledronic acid on aromatase inhibitor (AI) associated bone loss (AIBL) in postmenopausal women (PMW) with early breast cancer (EBC) receiving adjuvant letrozole: 24 months (MOS) integrated follow-up of the Z-FAST/ZO-FAST trials
-
abstr 185PD
-
Frassoldati, A.; Brufsky, A.; Bundred, N.; Lambert-Falls, R.; Hadji, P.; Coleman, R. The effect of zoledronic acid on aromatase inhibitor (AI) associated bone loss (AIBL) in postmenopausal women (PMW) with early breast cancer (EBC) receiving adjuvant letrozole: 24 months (MOS) integrated follow-up of the Z-FAST/ZO-FAST trials. Ann Oncol 2008, 19 (suppl 8, abstr 185PD), viii78.
-
(2008)
Ann. Oncol.
, vol.19
, Issue.8 SUPPL.
-
-
Frassoldati, A.1
Brufsky, A.2
Bundred, N.3
Lambert-Falls, R.4
Hadji, P.5
Coleman, R.6
-
87
-
-
77950370156
-
The effects of adding zoledronic acid to neoadjuvant chemotherapy on tumour response; exploratory revidence for direct anti-tumour activity in breast cancer
-
on behalf of the AZURE BIG01/04 Investigators
-
Coleman, R. E.; Winter, M. C.; Cameron, D.; Bell, R.; Dodwell, D.; Keane, M. M.; Gil, M.; Ritchie, D.; Passos-Coelho, J. L.; Wheatley, D.; Burkinshaw, R.; Marshall, S. J.; Thorpe, H. on behalf of the AZURE (BIG01/04) Investigators. The effects of adding zoledronic acid to neoadjuvant chemotherapy on tumour response; exploratory revidence for direct anti-tumour activity in breast cancer. Br J Cancer 2010, 102, 1099-1105.
-
(2010)
Br. J. Cancer
, vol.102
, pp. 1099-1105
-
-
Coleman, R.E.1
Winter, M.C.2
Cameron, D.3
Bell, R.4
Dodwell, D.5
Keane, M.M.6
Gil, M.7
Ritchie, D.8
Passos-Coelho, J.L.9
Wheatley, D.10
Burkinshaw, R.11
Marshall, S.J.12
Thorpe, H.13
-
88
-
-
77958010351
-
Anti-angiogenic potential of ZOL combined with neoadjuvant chemotherapy in invasive BC (ANZAC)
-
Presented at, Arlington, VA, October, abstr P67
-
Winter, M. C.; Evans, A.; Holen, I.; Coleman, R. E. Anti-angiogenic potential of ZOL combined with neoadjuvant chemotherapy in invasive BC (ANZAC). Presented at the IX International Meeting on Cancer Induced Bone Disease, Arlington, VA, October 28-31, 2009 (abstr P67).
-
(2009)
The IX International Meeting on Cancer Induced Bone Disease
, pp. 28-31
-
-
Winter, M.C.1
Evans, A.2
Holen, I.3
Coleman, R.E.4
-
89
-
-
77958003385
-
Evaluating the efficacy of zoledronic acid for the prevention of disease progression in patients with non-small cell lung cancer
-
Presented at, Berlin, Germany, September, abstr P-9056
-
Scagliotti, G.; Manegold, C.; de Marinis, F.; Engel-Riedel, W.; Albert, I.; Sallo, V.; Chen, Y. M.; Perez, J. R.; Kosmidis, P. Evaluating the efficacy of zoledronic acid for the prevention of disease progression in patients with non-small cell lung cancer. Presented at the joint 15th Congress of the European Cancer Organisation and 34th Congress of the European Society for Medical Oncology, Berlin, Germany, September 20-24, 2009 (abstr P-9056).
-
(2009)
The Joint 15th Congress of the European Cancer Organisation and 34th Congress of the European Society for Medical Oncology
, pp. 20-24
-
-
Scagliotti, G.1
Manegold, C.2
De Marinis, F.3
Engel-Riedel, W.4
Albert, I.5
Sallo, V.6
Chen, Y.M.7
Perez, J.R.8
Kosmidis, P.9
-
90
-
-
52349113945
-
-
ClinicalTrials.gov, Accessed August 26, 2010
-
ClinicalTrials.gov. Clinical Trials. Gov List Results. http://clinicaltrials.gov/ct2/results?intr=%22zoledronic+acid%22. Accessed August 26, 2010.
-
Clinical Trials. Gov List Results
-
-
-
91
-
-
77957356000
-
Evaluating the effects of zoledronic acid (ZOL) on overall survival (OS) in patients (Pts) with multiple myeloma (MM): Results of the Medical Research Council (MRC) Myeloma IX study [abstract 8021]
-
Presented at:, Chicago, IL, June
-
Morgan, G.; Davies, F.; Gregory, W.; Bell, S. E.; Szubert, A.; Navarro Coy, N.; Drayson, M.; Owen, R. G.; Jackson, G. H.; Child, J. A. Evaluating the effects of zoledronic acid (ZOL) on overall survival (OS) in patients (Pts) with multiple myeloma (MM): Results of the Medical Research Council (MRC) Myeloma IX study [abstract 8021]. Presented at: 46th Annual Meeting of the American Society of Clinical Oncology, Chicago, IL, June 4-8, 2010
-
(2010)
46th Annual Meeting of the American Society of Clinical Oncology
, pp. 4-8
-
-
Morgan, G.1
Davies, F.2
Gregory, W.3
Bell, S.E.4
Szubert, A.5
Coy, N.N.6
Drayson, M.7
Owen, R.G.8
Jackson, G.H.9
Child, J.A.10
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