Induction of γδ T-lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo [3]

Blood

Volumn 102, Issue 6, 2003, Pages 2310-2311

  Dieli, Francesco ^a   Gebbia, Nicola ^b   Poccia, Fabrizio ^b   Caccamo, Nadia ^b   Montesano, Carla ^b   Fulfaro, Fabio ^b   Arcara, Carlo ^b   Valerio, Maria R ^b   Meraviglia, Serena ^b   Di Sano, Caterina ^b   Sireci, Guido ^b   Salerno, Alfredo ^b  

^a UNIVERSITY OF PALERMO   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; INTERLEUKIN 2; ZOLEDRONIC ACID; IMIDAZOLE DERIVATIVE; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AGED; ANTINEOPLASTIC ACTIVITY; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; EFFECTOR CELL; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LETTER; LYMPHOCYTE FUNCTION; MALE; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; PILOT STUDY; PRIORITY JOURNAL; T LYMPHOCYTE; DRUG EFFECT; IMMUNOLOGY; METABOLISM;

DIPHOSPHONATES; HUMANS; IMIDAZOLES; LYMPHOMA, NON-HODGKIN; MULTIPLE MYELOMA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES;

EID: 0141567513     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-05-1655     Document Type: Letter

References (6)

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2. Kunzmann V, Bauer E, Feurle J, Weissinger F, Tony HP, Wilhelm M. Stimulation of gammadelta T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma. Blood. 2000;96:384-392.
3. Wilhelm M, Kunzmann V, Eckstein S, et al. γδ T cells for immune therapy of patients with lymphoid malignancies. Blood. 2003;102:200-206.
4. + T cell effectors in immunocompromised hosts and during active pulmonary tuberculosis. J Immunol. 2002;168:1484-1489.
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6. Ueta C, Kawasumi H, Fujiwara H, et al. Interleukin-12 activates human γδ T cells: synergistic effect of tumor necrosis factor-α. Eur J Immunol. 1996;26:3066-3073.