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Volumn 257, Issue 1, 2007, Pages 16-35

Bisphosphonates in cancer therapy

Author keywords

Bisphosphonate; Bone; Cancer; Metastasis

Indexed keywords

2 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 1,1 ETHANEBISPHOSPHONIC ACID TETRAISOPROPYL ESTER; 4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; ALENDRONIC ACID; ALPHA INTERFERON; ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CISPLATIN; CLODRONIC ACID; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; FLUINDOSTATIN; FLUOROURACIL; GEMCITABINE; HYDROXYUREA; IBANDRONIC ACID; IMATINIB; INCADRONIC ACID; METHOTREXATE; MINODRONIC ACID; NE 6790; PACLITAXEL; PAMIDRONIC ACID; RETINOIC ACID; RISEDRONIC ACID; SIMVASTATIN; TAXANE DERIVATIVE; TIPIFARNIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZOLEDRONIC ACID;

EID: 34648828862     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2007.07.007     Document Type: Review
Times cited : (180)

References (143)
  • 1
    • 0242503684 scopus 로고    scopus 로고
    • New insights into the molecular mechanisms of action of bisphosphonates
    • Rogers M.J. New insights into the molecular mechanisms of action of bisphosphonates. Curr. Pharm. Des. 9 (2003) 2643-2658
    • (2003) Curr. Pharm. Des. , vol.9 , pp. 2643-2658
    • Rogers, M.J.1
  • 2
    • 33750733277 scopus 로고    scopus 로고
    • Molecular mechanisms of action of bisphosphonates: current status
    • Roelofs A.J., Thompson K., Gordon S., and Rogers M.J. Molecular mechanisms of action of bisphosphonates: current status. Clin. Cancer Res. 12 (2006) 6222s-6230s
    • (2006) Clin. Cancer Res. , vol.12
    • Roelofs, A.J.1    Thompson, K.2    Gordon, S.3    Rogers, M.J.4
  • 3
  • 4
    • 20444486612 scopus 로고    scopus 로고
    • Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity
    • Clezardin P., Ebetino F.H., and Fournier P.G.J. Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity. Cancer Res. 65 (2005) 4971-4974
    • (2005) Cancer Res. , vol.65 , pp. 4971-4974
    • Clezardin, P.1    Ebetino, F.H.2    Fournier, P.G.J.3
  • 7
    • 0037304115 scopus 로고    scopus 로고
    • Antitumor effects of bisphosphonates
    • Green J. Antitumor effects of bisphosphonates. Cancer 97 (2003) 840-847
    • (2003) Cancer , vol.97 , pp. 840-847
    • Green, J.1
  • 8
    • 33845659966 scopus 로고    scopus 로고
    • Differential effects of bisphosphonates on breast cancer cell lines
    • Verdijk R., Franke H.R., Wolbers F., and Vermes I. Differential effects of bisphosphonates on breast cancer cell lines. Cancer Lett. 246 (2007) 308-312
    • (2007) Cancer Lett. , vol.246 , pp. 308-312
    • Verdijk, R.1    Franke, H.R.2    Wolbers, F.3    Vermes, I.4
  • 9
    • 33751034291 scopus 로고    scopus 로고
    • A third-generation bisphosphonate (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo
    • Sato K., Yuasa T., Nogawa M., Kimura S., Segawa H., Yokota A., and Maekawa T. A third-generation bisphosphonate (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br. J. Cancer 95 (2006) 1354-1361
    • (2006) Br. J. Cancer , vol.95 , pp. 1354-1361
    • Sato, K.1    Yuasa, T.2    Nogawa, M.3    Kimura, S.4    Segawa, H.5    Yokota, A.6    Maekawa, T.7
  • 10
    • 33746107560 scopus 로고    scopus 로고
    • Inhibitory effects of bisphosphonates on the proliferation of human ovarian cancer cell lines and the mechanism
    • Hirata J., Kikuchi Y., Kudoh K., Kita T., and Seto H. Inhibitory effects of bisphosphonates on the proliferation of human ovarian cancer cell lines and the mechanism. Med. Chem. 2 (2006) 223-226
    • (2006) Med. Chem. , vol.2 , pp. 223-226
    • Hirata, J.1    Kikuchi, Y.2    Kudoh, K.3    Kita, T.4    Seto, H.5
  • 11
    • 28844486699 scopus 로고    scopus 로고
    • Pamidronate induced anti-proliferative, apoptotic, and anti-migratory effects in hepatocellular carcinoma
    • Wada A., Fukui K., Sawai Y., Imanaka K., Kiso S., Tamura S., et al. Pamidronate induced anti-proliferative, apoptotic, and anti-migratory effects in hepatocellular carcinoma. J. Hepatol. 44 (2006) 142-150
    • (2006) J. Hepatol. , vol.44 , pp. 142-150
    • Wada, A.1    Fukui, K.2    Sawai, Y.3    Imanaka, K.4    Kiso, S.5    Tamura, S.6
  • 12
    • 27644523717 scopus 로고    scopus 로고
    • Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells
    • Chuah C., Barnes D.J., Kwok M., Corbin A., Deininger M.W., Druker B.J., and Melo J.V. Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells. Leukemia 19 (2005) 1896-1904
    • (2005) Leukemia , vol.19 , pp. 1896-1904
    • Chuah, C.1    Barnes, D.J.2    Kwok, M.3    Corbin, A.4    Deininger, M.W.5    Druker, B.J.6    Melo, J.V.7
  • 13
    • 27644568995 scopus 로고    scopus 로고
    • The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NfkappaB pathway in osteosarcoma cells
    • Inoue R., Matsuki N.A., Jing G., Kanematsu T., Abe K., and Hirata M. The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NfkappaB pathway in osteosarcoma cells. Br. J. Pharmacol. 146 (2005) 633-641
    • (2005) Br. J. Pharmacol. , vol.146 , pp. 633-641
    • Inoue, R.1    Matsuki, N.A.2    Jing, G.3    Kanematsu, T.4    Abe, K.5    Hirata, M.6
  • 14
    • 9644262751 scopus 로고    scopus 로고
    • Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling
    • Yamagishi S., Abe R., Inagaki Y., Nakamura K., Sugawara H., Inokuma D., et al. Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling. Am. J. Pathol. 165 (2004) 1865-1874
    • (2004) Am. J. Pathol. , vol.165 , pp. 1865-1874
    • Yamagishi, S.1    Abe, R.2    Inagaki, Y.3    Nakamura, K.4    Sugawara, H.5    Inokuma, D.6
  • 15
    • 0037132352 scopus 로고    scopus 로고
    • The bisphosphonate zoledronic acid impairs Ras membrane localisation and induces cytochrome c release in breast cancer cells
    • Senaratne S.G., Mansi J.L., and Colston K.W. The bisphosphonate zoledronic acid impairs Ras membrane localisation and induces cytochrome c release in breast cancer cells. Br. J. Cancer 87 (2002) 1340
    • (2002) Br. J. Cancer , vol.87 , pp. 1340
    • Senaratne, S.G.1    Mansi, J.L.2    Colston, K.W.3
  • 17
    • 12144289799 scopus 로고    scopus 로고
    • p53-independent anti-tumor effects of the nitrogen-containing bisphosphonate zoledronic acid
    • Kuroda J., Kimura S., Segawa H., Sato K., Matsumoto S., Nogawa M., et al. p53-independent anti-tumor effects of the nitrogen-containing bisphosphonate zoledronic acid. Cancer Sci. 95 (2004) 186-192
    • (2004) Cancer Sci. , vol.95 , pp. 186-192
    • Kuroda, J.1    Kimura, S.2    Segawa, H.3    Sato, K.4    Matsumoto, S.5    Nogawa, M.6
  • 18
    • 33845910925 scopus 로고    scopus 로고
    • Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease
    • Ory B., Blanchard F., Battaglia S., Gouin F., Redini F., and Heymann D. Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease. Mol. Pharmacol. 71 (2007) 333-343
    • (2007) Mol. Pharmacol. , vol.71 , pp. 333-343
    • Ory, B.1    Blanchard, F.2    Battaglia, S.3    Gouin, F.4    Redini, F.5    Heymann, D.6
  • 19
    • 33644539542 scopus 로고    scopus 로고
    • A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates
    • Mönkkönen H., Auriola S., Lehenkari P., Kellinsalmi M., Hassinen I.E., Vepsäläinen J., and Mönkkönen J. A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates. Br. J. Pharmacol. 147 (2006) 437-445
    • (2006) Br. J. Pharmacol. , vol.147 , pp. 437-445
    • Mönkkönen, H.1    Auriola, S.2    Lehenkari, P.3    Kellinsalmi, M.4    Hassinen, I.E.5    Vepsäläinen, J.6    Mönkkönen, J.7
  • 20
    • 0036238837 scopus 로고    scopus 로고
    • Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite
    • Lehenkari P.P., Kellinsalmi M., Napankangas J.P., Ylitalo K.V., Mönkkönen J., Rogers M.J., et al. Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite. Mol. Pharmacol. 61 (2002) 1255-1262
    • (2002) Mol. Pharmacol. , vol.61 , pp. 1255-1262
    • Lehenkari, P.P.1    Kellinsalmi, M.2    Napankangas, J.P.3    Ylitalo, K.V.4    Mönkkönen, J.5    Rogers, M.J.6
  • 21
    • 34648874952 scopus 로고    scopus 로고
    • H. Mönkkönen, P. Ottewell, I. Holen, A. Evans, D. Lefley, J. Kuokkanen, et al., Zoledronic acid induced IPP/ApppI accumulation in different cancer cell lines and in vivo, in: VI International Conference on Cancer-Induced Bone Disease (CIBD) San Antonio, Texas, USA, December 10-14, 2006.
  • 22
    • 0034595077 scopus 로고    scopus 로고
    • The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol
    • Flach J., Antoni I., Villemin P., Bentzen C.L., and Niesor E.J. The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol. Biochem. Biophys. Res. Commun. 270 (2000) 240-246
    • (2000) Biochem. Biophys. Res. Commun. , vol.270 , pp. 240-246
    • Flach, J.1    Antoni, I.2    Villemin, P.3    Bentzen, C.L.4    Niesor, E.J.5
  • 23
    • 14644422221 scopus 로고    scopus 로고
    • Induction of apoptosis in breast cancer cells by apomine is mediated by caspase and p38 mitogen activated protein kinase activation
    • Lowe L.C., Senaratne S.G., and Colston K.W. Induction of apoptosis in breast cancer cells by apomine is mediated by caspase and p38 mitogen activated protein kinase activation. Biochem. Biophys. Res. Commun. 329 (2005) 772-779
    • (2005) Biochem. Biophys. Res. Commun. , vol.329 , pp. 772-779
    • Lowe, L.C.1    Senaratne, S.G.2    Colston, K.W.3
  • 24
    • 33845910395 scopus 로고    scopus 로고
    • Cytotoxic activity of apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma call line
    • Pourpak A., Dorr R.T., Meyers R.O., Powell M.B., and Stratton S.P. Cytotoxic activity of apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma call line. Invest. New Drugs 25 (2007) 107-114
    • (2007) Invest. New Drugs , vol.25 , pp. 107-114
    • Pourpak, A.1    Dorr, R.T.2    Meyers, R.O.3    Powell, M.B.4    Stratton, S.P.5
  • 25
  • 26
    • 0037723835 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway
    • Iguchi T., Miyakawa Y., Yamamoto K., Kizaki M., and Ikeda Y. Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway. Cell. Signal. 15 (2003) 719-727
    • (2003) Cell. Signal. , vol.15 , pp. 719-727
    • Iguchi, T.1    Miyakawa, Y.2    Yamamoto, K.3    Kizaki, M.4    Ikeda, Y.5
  • 27
    • 0035135687 scopus 로고    scopus 로고
    • Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation
    • Reszka A.A., Halasy-Nagy J., and Rodan G.A. Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation. Mol. Pharmacol. 59 (2001) 193-202
    • (2001) Mol. Pharmacol. , vol.59 , pp. 193-202
    • Reszka, A.A.1    Halasy-Nagy, J.2    Rodan, G.A.3
  • 28
    • 0019941487 scopus 로고
    • Biological diversity in metastatic neoplasms, origins and implications
    • Fidler I.J., and Hart I.R. Biological diversity in metastatic neoplasms, origins and implications. Science 217 (1982) 998-1003
    • (1982) Science , vol.217 , pp. 998-1003
    • Fidler, I.J.1    Hart, I.R.2
  • 29
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 0034094341 scopus 로고    scopus 로고
    • Interactions between cancer cells and the endothelium in metastasis
    • Orr F.W., Wang H.H., Lafrenie R.M., Scherbarth S., and Nance D.M. Interactions between cancer cells and the endothelium in metastasis. J. Pathol. 190 (2000) 310-329
    • (2000) J. Pathol. , vol.190 , pp. 310-329
    • Orr, F.W.1    Wang, H.H.2    Lafrenie, R.M.3    Scherbarth, S.4    Nance, D.M.5
  • 31
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermark J., and Kähäri V.M. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J. 13 (1999) 781-792
    • (1999) FASEB J. , vol.13 , pp. 781-792
    • Westermark, J.1    Kähäri, V.M.2
  • 33
    • 0030826872 scopus 로고    scopus 로고
    • Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices
    • Boissier S., Magnetto S., Frappart L., Cuzin B., Ebetino F.H., Delmas P.D., and Clezardin P. Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices. Cancer Res. 57 (1997) 3890-3894
    • (1997) Cancer Res. , vol.57 , pp. 3890-3894
    • Boissier, S.1    Magnetto, S.2    Frappart, L.3    Cuzin, B.4    Ebetino, F.H.5    Delmas, P.D.6    Clezardin, P.7
  • 34
    • 3242771333 scopus 로고    scopus 로고
    • Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenylation
    • Coxon J.P., Oades G.M., Kirby R.S., and Colston K.W. Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenylation. BJU Int. 94 (2004) 164-170
    • (2004) BJU Int. , vol.94 , pp. 164-170
    • Coxon, J.P.1    Oades, G.M.2    Kirby, R.S.3    Colston, K.W.4
  • 35
    • 0037329747 scopus 로고    scopus 로고
    • Cellular functions of Rap1 GTP-binding protein: a pattern emerges
    • Caron E. Cellular functions of Rap1 GTP-binding protein: a pattern emerges. J. Cell Sci. 116 (2003) 435-440
    • (2003) J. Cell Sci. , vol.116 , pp. 435-440
    • Caron, E.1
  • 36
    • 20544473523 scopus 로고    scopus 로고
    • Zoledronic acid down-regulates adhesion molecules of bone marrow stromal cells in multiple myeloma
    • Corso A., Ferretti E., Lunghi M., Zappasodi P., Mangiacavalli S., De Amici M., et al. Zoledronic acid down-regulates adhesion molecules of bone marrow stromal cells in multiple myeloma. Cancer 104 (2005) 118-125
    • (2005) Cancer , vol.104 , pp. 118-125
    • Corso, A.1    Ferretti, E.2    Lunghi, M.3    Zappasodi, P.4    Mangiacavalli, S.5    De Amici, M.6
  • 37
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: bidirectional, allosteric signaling machines
    • Hynes R.O. Integrins: bidirectional, allosteric signaling machines. Cell 110 (2002) 673-687
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 38
    • 25444529945 scopus 로고    scopus 로고
    • The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer
    • Miwa S., Mizokami A., Keller E.T., Taichman R., Zhang J., and Namiki M. The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer. Cancer Res. 65 (2005) 8818-8825
    • (2005) Cancer Res. , vol.65 , pp. 8818-8825
    • Miwa, S.1    Mizokami, A.2    Keller, E.T.3    Taichman, R.4    Zhang, J.5    Namiki, M.6
  • 39
    • 22944434893 scopus 로고    scopus 로고
    • Alendronate inhibits proliferation and invasion of epidermoid carcinoma cells in vitro
    • Muller S., Migianu E., Lecouvey M., Kraemer M., and Oudar O. Alendronate inhibits proliferation and invasion of epidermoid carcinoma cells in vitro. Anticancer Res. 25 (2005) 2655-2660
    • (2005) Anticancer Res. , vol.25 , pp. 2655-2660
    • Muller, S.1    Migianu, E.2    Lecouvey, M.3    Kraemer, M.4    Oudar, O.5
  • 40
    • 0038792653 scopus 로고    scopus 로고
    • New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects
    • Denoyelle C., Hong L., Vannier J.P., Soria J., and Soria C. New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects. Br. J. Cancer 88 (2003) 1631-1640
    • (2003) Br. J. Cancer , vol.88 , pp. 1631-1640
    • Denoyelle, C.1    Hong, L.2    Vannier, J.P.3    Soria, J.4    Soria, C.5
  • 41
    • 1942454714 scopus 로고    scopus 로고
    • Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines
    • Cheng Y.Y., Huang L., Lee K.M., Li K., and Kumta S.M. Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines. Pediatr. Blood Cancer 42 (2004) 410-415
    • (2004) Pediatr. Blood Cancer , vol.42 , pp. 410-415
    • Cheng, Y.Y.1    Huang, L.2    Lee, K.M.3    Li, K.4    Kumta, S.M.5
  • 42
    • 12544258226 scopus 로고    scopus 로고
    • Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model
    • Hashimoto K., Morishige K., Sawada K., Tahara M., Kawagishi R., Ikebuchi Y., et al. Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model. Cancer Res. 65 (2005) 540-545
    • (2005) Cancer Res. , vol.65 , pp. 540-545
    • Hashimoto, K.1    Morishige, K.2    Sawada, K.3    Tahara, M.4    Kawagishi, R.5    Ikebuchi, Y.6
  • 43
    • 4043072703 scopus 로고    scopus 로고
    • Differential inhibition of invasion and proliferation by bisphosphonates: anti-metastatic potential of zoledronic acid in prostate cancer
    • Montague R., Hart C., George N., Ramani V., Brown M., and Clarke N. Differential inhibition of invasion and proliferation by bisphosphonates: anti-metastatic potential of zoledronic acid in prostate cancer. Eur. Urol. 46 (2004) 389-402
    • (2004) Eur. Urol. , vol.46 , pp. 389-402
    • Montague, R.1    Hart, C.2    George, N.3    Ramani, V.4    Brown, M.5    Clarke, N.6
  • 44
    • 0034980406 scopus 로고    scopus 로고
    • Preclinical studies with zoledronic acid and other bisphosphonates: impact on the bone microenvironment
    • Mundy G.R., Yoneda T., and Hiraga T. Preclinical studies with zoledronic acid and other bisphosphonates: impact on the bone microenvironment. Semin. Oncol. 28 (2001) 35-44
    • (2001) Semin. Oncol. , vol.28 , pp. 35-44
    • Mundy, G.R.1    Yoneda, T.2    Hiraga, T.3
  • 45
    • 34648877896 scopus 로고    scopus 로고
    • The role of bisphosphonates in breast and prostate cancer
    • Brown J.E., Neville-Webbe H., and Coleman R.E. The role of bisphosphonates in breast and prostate cancer. J. Clin. Oncol. 18 (2004) 1378-1391
    • (2004) J. Clin. Oncol. , vol.18 , pp. 1378-1391
    • Brown, J.E.1    Neville-Webbe, H.2    Coleman, R.E.3
  • 46
    • 0037236978 scopus 로고    scopus 로고
    • Zoledronic acid exhibits inhibitory effects on osteoblastic and osteolytic metastases of prostate cancer
    • Corey E., Brown L.G., and Quinn J.E. Zoledronic acid exhibits inhibitory effects on osteoblastic and osteolytic metastases of prostate cancer. Clin. Cancer Res. 9 (2003) 295-306
    • (2003) Clin. Cancer Res. , vol.9 , pp. 295-306
    • Corey, E.1    Brown, L.G.2    Quinn, J.E.3
  • 47
    • 0036181668 scopus 로고    scopus 로고
    • Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity
    • Yaccoby S., Pearse R.N., Johnson C.L., Barlogie B., Choi Y., and Epstein J. Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity. Br. J. Haematol. 116 (2002) 278-290
    • (2002) Br. J. Haematol. , vol.116 , pp. 278-290
    • Yaccoby, S.1    Pearse, R.N.2    Johnson, C.L.3    Barlogie, B.4    Choi, Y.5    Epstein, J.6
  • 48
    • 0242308942 scopus 로고    scopus 로고
    • Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival
    • Croucher P.I., de Hendrik R., Perry M.J., Hijzen A., Shipman C.M., Lippitt J., et al. Zoledronic acid treatment of 5T2MM-bearing mice inhibits the development of myeloma bone disease: evidence for decreased osteolysis, tumor burden and angiogenesis, and increased survival. J. Bone Miner. Res. 18 (2003) 482-492
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 482-492
    • Croucher, P.I.1    de Hendrik, R.2    Perry, M.J.3    Hijzen, A.4    Shipman, C.M.5    Lippitt, J.6
  • 49
    • 26444574115 scopus 로고    scopus 로고
    • Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma
    • Zhou Z., Guan H., Duan X., and Kleinerman E.S. Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma. Cancer 104 (2005) 1713-1720
    • (2005) Cancer , vol.104 , pp. 1713-1720
    • Zhou, Z.1    Guan, H.2    Duan, X.3    Kleinerman, E.S.4
  • 50
    • 28044467108 scopus 로고    scopus 로고
    • Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice
    • Ory B., Heymann M.F., Kamijo A., Gouin F., Heymann D., and Redini F. Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice. Cancer 104 (2005) 2522-2529
    • (2005) Cancer , vol.104 , pp. 2522-2529
    • Ory, B.1    Heymann, M.F.2    Kamijo, A.3    Gouin, F.4    Heymann, D.5    Redini, F.6
  • 51
    • 33746337357 scopus 로고    scopus 로고
    • Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival
    • Gouin F., Ory B., Redini F., and Heymann D. Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival. Int. J. Cancer 119 (2006) 980-984
    • (2006) Int. J. Cancer , vol.119 , pp. 980-984
    • Gouin, F.1    Ory, B.2    Redini, F.3    Heymann, D.4
  • 52
    • 33847771427 scopus 로고    scopus 로고
    • Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis
    • Daubiné F., Le Gall C., Gasser J., Green J., and Clezardin P. Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis. J. Natl. Cancer Inst. 99 (2007) 322-330
    • (2007) J. Natl. Cancer Inst. , vol.99 , pp. 322-330
    • Daubiné, F.1    Le Gall, C.2    Gasser, J.3    Green, J.4    Clezardin, P.5
  • 53
    • 4944239035 scopus 로고    scopus 로고
    • An aminobisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
    • Giraudo E., Inoue M., and Hanahan D. An aminobisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis. J. Clin. Invest. 114 (2004) 623-633
    • (2004) J. Clin. Invest. , vol.114 , pp. 623-633
    • Giraudo, E.1    Inoue, M.2    Hanahan, D.3
  • 54
    • 10444274954 scopus 로고    scopus 로고
    • Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines
    • Matsumoto S., Kimura S., Segawa H., Kuroda J., Yuasa T., Sato K., et al. Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines. Lung Cancer 47 (2005) 31-39
    • (2005) Lung Cancer , vol.47 , pp. 31-39
    • Matsumoto, S.1    Kimura, S.2    Segawa, H.3    Kuroda, J.4    Yuasa, T.5    Sato, K.6
  • 56
    • 33847024021 scopus 로고    scopus 로고
    • Differential effects of Ca(2+) on bisphosphonate-induced growth inhibition in breast cancer and mesothelioma cells
    • Merrell M.A., Wakchoure S., Ilvesaro J.M., Zinn K., Gehrs B., Lehenkari P.P., et al. Differential effects of Ca(2+) on bisphosphonate-induced growth inhibition in breast cancer and mesothelioma cells. Eur. J. Pharmacol. 559 (2007) 21-31
    • (2007) Eur. J. Pharmacol. , vol.559 , pp. 21-31
    • Merrell, M.A.1    Wakchoure, S.2    Ilvesaro, J.M.3    Zinn, K.4    Gehrs, B.5    Lehenkari, P.P.6
  • 57
    • 0030078149 scopus 로고    scopus 로고
    • Accumulation of bisphosphonates in the aorta and some other tissues of healthy and atherosclerotic rabbits
    • Ylitalo R., Mönkkönen J., Urtti A., and Ylitalo P. Accumulation of bisphosphonates in the aorta and some other tissues of healthy and atherosclerotic rabbits. J. Lab. Clin. Med. 127 (1996) 200-206
    • (1996) J. Lab. Clin. Med. , vol.127 , pp. 200-206
    • Ylitalo, R.1    Mönkkönen, J.2    Urtti, A.3    Ylitalo, P.4
  • 58
    • 0029101805 scopus 로고
    • Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice
    • Sasaki A., Boyce B.F., Story B., Wright K.R., Chapman M., Boyce R., et al. Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice. Cancer Res. 55 (1995) 3551-3557
    • (1995) Cancer Res. , vol.55 , pp. 3551-3557
    • Sasaki, A.1    Boyce, B.F.2    Story, B.3    Wright, K.R.4    Chapman, M.5    Boyce, R.6
  • 59
    • 0035360867 scopus 로고    scopus 로고
    • The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231human breast cancer cells in bone metastases
    • Hiraga T., Williams P.J., Mundy G.R., and Yoneda T. The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231human breast cancer cells in bone metastases. Cancer Res. 61 (2001) 4418-4424
    • (2001) Cancer Res. , vol.61 , pp. 4418-4424
    • Hiraga, T.1    Williams, P.J.2    Mundy, G.R.3    Yoneda, T.4
  • 60
    • 0037249302 scopus 로고    scopus 로고
    • A novel bisphosphonate minodronate (YM529) specifically inhibits osteolytic bone metastasis produced by human small-cell lung-cancer cells in NK-cell depleted SCID mice
    • Zhang H., Yano S., Miki T., Goto H., Kanematsu T., Muguruma H., et al. A novel bisphosphonate minodronate (YM529) specifically inhibits osteolytic bone metastasis produced by human small-cell lung-cancer cells in NK-cell depleted SCID mice. Clin. Exp. Metastasis 20 (2003) 153-159
    • (2003) Clin. Exp. Metastasis , vol.20 , pp. 153-159
    • Zhang, H.1    Yano, S.2    Miki, T.3    Goto, H.4    Kanematsu, T.5    Muguruma, H.6
  • 61
    • 0036777368 scopus 로고    scopus 로고
    • The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs
    • Michigami T., Hiraga T., and Williams P.J. The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs. Breast Cancer Res. Treat. 75 (2002) 249-258
    • (2002) Breast Cancer Res. Treat. , vol.75 , pp. 249-258
    • Michigami, T.1    Hiraga, T.2    Williams, P.J.3
  • 62
    • 3042729728 scopus 로고    scopus 로고
    • Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model
    • Hiraga T., Williams P.J., Ueda A., Tamura D., and Yoneda T. Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model. Clin. Cancer Res. 10 (2004) 4559-4677
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4559-4677
    • Hiraga, T.1    Williams, P.J.2    Ueda, A.3    Tamura, D.4    Yoneda, T.5
  • 63
    • 0033914013 scopus 로고    scopus 로고
    • Angiogenesis and cancer metastasis
    • Fidler IJ. Angiogenesis and cancer metastasis. Cancer J. Suppl. 2 (2000) 134-141
    • (2000) Cancer J. Suppl. , vol.2 , pp. 134-141
    • Fidler, IJ.1
  • 64
    • 0035160312 scopus 로고    scopus 로고
    • Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
    • Lyden D., Koichi H., Diass S., Costas C., Blaikie P., Butrosi L., et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat. Med. 7 (2001) 1194-1201
    • (2001) Nat. Med. , vol.7 , pp. 1194-1201
    • Lyden, D.1    Koichi, H.2    Diass, S.3    Costas, C.4    Blaikie, P.5    Butrosi, L.6
  • 65
    • 0037112368 scopus 로고    scopus 로고
    • Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats
    • Fournier P., Boissier S., Filleur S., Guglielmi J., Cabon F., Colombel M., and Clezardin P. Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats. Cancer Res. 62 (2002) 6538-6544
    • (2002) Cancer Res. , vol.62 , pp. 6538-6544
    • Fournier, P.1    Boissier, S.2    Filleur, S.3    Guglielmi, J.4    Cabon, F.5    Colombel, M.6    Clezardin, P.7
  • 67
    • 0242353251 scopus 로고    scopus 로고
    • Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death
    • Bezzi M., Hasmim M., Bieler G., Dormond O., and Rüegg C. Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death. J. Biol. Chem. 278 (2003) 43603-43614
    • (2003) J. Biol. Chem. , vol.278 , pp. 43603-43614
    • Bezzi, M.1    Hasmim, M.2    Bieler, G.3    Dormond, O.4    Rüegg, C.5
  • 69
    • 10744227993 scopus 로고    scopus 로고
    • Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients
    • Santini D., Vincenzi B., Dicuonzo G., Avvisati G., Massacesi C., Battistoni F., et al. Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients. Clin. Cancer Res. 9 (2003) 2893-2897
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2893-2897
    • Santini, D.1    Vincenzi, B.2    Dicuonzo, G.3    Avvisati, G.4    Massacesi, C.5    Battistoni, F.6
  • 71
    • 0034660687 scopus 로고    scopus 로고
    • Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma
    • Kunzmann V., Bauer E., Feurle J., Weißinger F., Tony H.P., and Wilhelm M. Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma. Blood 96 (2000) 384-392
    • (2000) Blood , vol.96 , pp. 384-392
    • Kunzmann, V.1    Bauer, E.2    Feurle, J.3    Weißinger, F.4    Tony, H.P.5    Wilhelm, M.6
  • 72
    • 0035339933 scopus 로고    scopus 로고
    • Essential requirement of antigen presentation by monocyte lineage cells for the activation of primary human γδT cells by aminobisphosphonate antigen
    • Miyagawa F., Tanaka Y., Yamashita S., and Minato N. Essential requirement of antigen presentation by monocyte lineage cells for the activation of primary human γδT cells by aminobisphosphonate antigen. J. Immunol. 166 (2001) 5508-5514
    • (2001) J. Immunol. , vol.166 , pp. 5508-5514
    • Miyagawa, F.1    Tanaka, Y.2    Yamashita, S.3    Minato, N.4
  • 73
    • 0141567513 scopus 로고    scopus 로고
    • Induction of γδT-lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo
    • Dieli F., Gebbia N., Poccia F., Caccamo N., Montesano C., Fulfaro F., et al. Induction of γδT-lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo. Blood 102 (2003) 2310-2311
    • (2003) Blood , vol.102 , pp. 2310-2311
    • Dieli, F.1    Gebbia, N.2    Poccia, F.3    Caccamo, N.4    Montesano, C.5    Fulfaro, F.6
  • 75
    • 12944334190 scopus 로고    scopus 로고
    • From molds and macrophages to mevalonate: a decade of progress in understanding the molecular mode of action of bisphosphonates
    • Rogers M.J. From molds and macrophages to mevalonate: a decade of progress in understanding the molecular mode of action of bisphosphonates. Calcif. Tissue Int. 75 (2004) 451-461
    • (2004) Calcif. Tissue Int. , vol.75 , pp. 451-461
    • Rogers, M.J.1
  • 76
    • 9144228037 scopus 로고    scopus 로고
    • Quantitative structure-activity relationships for T cell activation by bisphosphonates
    • Sanders J.M., Ghosh S., Chan J.M.W., Meints G., Wang H., Raker A.M., et al. Quantitative structure-activity relationships for T cell activation by bisphosphonates. J. Med. Chem. 47 (2004) 375-384
    • (2004) J. Med. Chem. , vol.47 , pp. 375-384
    • Sanders, J.M.1    Ghosh, S.2    Chan, J.M.W.3    Meints, G.4    Wang, H.5    Raker, A.M.6
  • 77
    • 0036007415 scopus 로고    scopus 로고
    • Human γδ T cells: a nonredundant system in the immune-surveillance against cancer
    • Ferrarini M., Ferrero E., Dagna L., Poggi A., and Zocchi M.R. Human γδ T cells: a nonredundant system in the immune-surveillance against cancer. Trends Immunol. 23 (2002) 14-18
    • (2002) Trends Immunol. , vol.23 , pp. 14-18
    • Ferrarini, M.1    Ferrero, E.2    Dagna, L.3    Poggi, A.4    Zocchi, M.R.5
  • 78
    • 0037379291 scopus 로고    scopus 로고
    • Requirement of species-specific interactions for the activation of human gamma delta T cells by pamidronate
    • Kato Y., Tanaka Y., Tanaka H., Yamashita S., and Minato N. Requirement of species-specific interactions for the activation of human gamma delta T cells by pamidronate. J. Immunol. 170 (2003) 3608-3613
    • (2003) J. Immunol. , vol.170 , pp. 3608-3613
    • Kato, Y.1    Tanaka, Y.2    Tanaka, H.3    Yamashita, S.4    Minato, N.5
  • 79
    • 0035161195 scopus 로고    scopus 로고
    • Synthetic phosphoantigens enhance human Vgamma9Vdelta2 T lymphocytes killing of non-Hodgkin's B lymphoma
    • Sicard H., Al Saati T., Delsol G., and Fournie J.J. Synthetic phosphoantigens enhance human Vgamma9Vdelta2 T lymphocytes killing of non-Hodgkin's B lymphoma. Mol. Med. 7 (2001) 711-722
    • (2001) Mol. Med. , vol.7 , pp. 711-722
    • Sicard, H.1    Al Saati, T.2    Delsol, G.3    Fournie, J.J.4
  • 80
    • 0028977873 scopus 로고
    • V gamma 2V delta TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer
    • Bukowski J.F., Morita C.T., Tanaka Y., Bloom B.R., Brenner M.B., and Band H. V gamma 2V delta TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer. J. Immunol. 154 (1995) 998-1006
    • (1995) J. Immunol. , vol.154 , pp. 998-1006
    • Bukowski, J.F.1    Morita, C.T.2    Tanaka, Y.3    Bloom, B.R.4    Brenner, M.B.5    Band, H.6
  • 81
    • 20444445149 scopus 로고    scopus 로고
    • Cytotoxic effects of γδ T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy
    • Sato K., Kimura S., Segawa H., Yokota A., Matsumoto S., Kuroda J., et al. Cytotoxic effects of γδ T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy. Int. J. Cancer 116 (2005) 94-99
    • (2005) Int. J. Cancer , vol.116 , pp. 94-99
    • Sato, K.1    Kimura, S.2    Segawa, H.3    Yokota, A.4    Matsumoto, S.5    Kuroda, J.6
  • 82
    • 9144241718 scopus 로고    scopus 로고
    • Characterization of tumor reactivity of human Vγ9Vδ2 T cells in vitro and in SCID mice in vivo
    • Kabelitz D., Wesch D., Pitters E., and Zöller M. Characterization of tumor reactivity of human Vγ9Vδ2 T cells in vitro and in SCID mice in vivo. J. Immunol. 173 (2004) 6767-6776
    • (2004) J. Immunol. , vol.173 , pp. 6767-6776
    • Kabelitz, D.1    Wesch, D.2    Pitters, E.3    Zöller, M.4
  • 83
    • 9144261113 scopus 로고    scopus 로고
    • Effect of human natural killer and γδ T cells on the growth of human antologous melanoma xenografts in SCID mice
    • Lozupone F., Pende D., Burgio V.L., Castelli C., Spada M., Venditti M., et al. Effect of human natural killer and γδ T cells on the growth of human antologous melanoma xenografts in SCID mice. Cancer Res. 64 (2004) 378-385
    • (2004) Cancer Res. , vol.64 , pp. 378-385
    • Lozupone, F.1    Pende, D.2    Burgio, V.L.3    Castelli, C.4    Spada, M.5    Venditti, M.6
  • 84
    • 0035342534 scopus 로고    scopus 로고
    • Anti-tumor effects of human peripheral gammadelta T cells in a mouse tumor model
    • Zheng B.J., Chan K.W., Im S., Chua D., Sham J.S., Tin P.C., et al. Anti-tumor effects of human peripheral gammadelta T cells in a mouse tumor model. Int. J. Cancer 92 (2001) 421-425
    • (2001) Int. J. Cancer , vol.92 , pp. 421-425
    • Zheng, B.J.1    Chan, K.W.2    Im, S.3    Chua, D.4    Sham, J.S.5    Tin, P.C.6
  • 85
    • 33748804427 scopus 로고    scopus 로고
    • The effect of zoledronic acid on the function and differentiation of myeloid cells
    • Wolf A.M., Rumpold H., Tilg H., Gastl G., and Gunsilius E. The effect of zoledronic acid on the function and differentiation of myeloid cells. Haematologica 91 (2006) 1165-1171
    • (2006) Haematologica , vol.91 , pp. 1165-1171
    • Wolf, A.M.1    Rumpold, H.2    Tilg, H.3    Gastl, G.4    Gunsilius, E.5
  • 86
    • 29844445611 scopus 로고    scopus 로고
    • Peripheral gammadelta T-lymphocytes as an innovative tool in immunotherapy for metastatic renal cell carcinoma
    • Viey E., Laplace C., and Escudier B. Peripheral gammadelta T-lymphocytes as an innovative tool in immunotherapy for metastatic renal cell carcinoma. Expert Rev. Anticancer Ther. 5 (2005) 973-986
    • (2005) Expert Rev. Anticancer Ther. , vol.5 , pp. 973-986
    • Viey, E.1    Laplace, C.2    Escudier, B.3
  • 87
    • 33846454363 scopus 로고    scopus 로고
    • Perspectives of γδ T cells in tumor immunology
    • Kabelitz D., Wesch D., and He W. Perspectives of γδ T cells in tumor immunology. Cancer Res. 67 (2007) 5-8
    • (2007) Cancer Res. , vol.67 , pp. 5-8
    • Kabelitz, D.1    Wesch, D.2    He, W.3
  • 88
    • 2542568696 scopus 로고    scopus 로고
    • Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin
    • Green A.E., Lissina A., Hutchinson S.L., Hewitt R.E., Temple B., James D., et al. Recognition of nonpeptide antigens by human V gamma 9V delta 2 T cells requires contact with cells of human origin. Clin. Exp. Immunol. 136 (2004) 472-482
    • (2004) Clin. Exp. Immunol. , vol.136 , pp. 472-482
    • Green, A.E.1    Lissina, A.2    Hutchinson, S.L.3    Hewitt, R.E.4    Temple, B.5    James, D.6
  • 89
    • 33644779729 scopus 로고    scopus 로고
    • Immunosurveillance and immunoregulation by gammadelta T cells
    • Girardi M. Immunosurveillance and immunoregulation by gammadelta T cells. J. Invest. Dermatol. 126 (2006) 25-31
    • (2006) J. Invest. Dermatol. , vol.126 , pp. 25-31
    • Girardi, M.1
  • 90
    • 0037455013 scopus 로고    scopus 로고
    • Human T cell receptor γδ T cells γδ recognize endogenous mevalonate metabolites in tumor cells
    • Gober H.J., Kistowska M., Angman L., Jeno P., Mori L., and De Libero G. Human T cell receptor γδ T cells γδ recognize endogenous mevalonate metabolites in tumor cells. J. Exp. Med. 197 (2003) 163-168
    • (2003) J. Exp. Med. , vol.197 , pp. 163-168
    • Gober, H.J.1    Kistowska, M.2    Angman, L.3    Jeno, P.4    Mori, L.5    De Libero, G.6
  • 91
    • 0034689029 scopus 로고    scopus 로고
    • Selfrecognition of CD1 by gamma/delta T cells: implications for innate immunity
    • Spada F.M., Grant E.P., Peters P.J., Sugita M., Melian M., and Leslie D.S. Selfrecognition of CD1 by gamma/delta T cells: implications for innate immunity. J. Exp. Med. 191 (2000) 937-948
    • (2000) J. Exp. Med. , vol.191 , pp. 937-948
    • Spada, F.M.1    Grant, E.P.2    Peters, P.J.3    Sugita, M.4    Melian, M.5    Leslie, D.S.6
  • 92
    • 23844514335 scopus 로고    scopus 로고
    • MICA expressed by multiple myeloma and monoclonal gammopathy of undetermined significance plasma cells costimulates pamidronate-activated gammadelta lymphocytes
    • Girlanda S., Fortis C., Belloni D., Ferrero E., Ticozzi P., Sciorati C., et al. MICA expressed by multiple myeloma and monoclonal gammopathy of undetermined significance plasma cells costimulates pamidronate-activated gammadelta lymphocytes. Cancer Res. 65 (2005) 7502-7508
    • (2005) Cancer Res. , vol.65 , pp. 7502-7508
    • Girlanda, S.1    Fortis, C.2    Belloni, D.3    Ferrero, E.4    Ticozzi, P.5    Sciorati, C.6
  • 95
    • 19944432463 scopus 로고    scopus 로고
    • Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-released structure and apolipoprotein A-I
    • Scotet E., Martinez L.O., Grant E., Barbaras R., Jeno P., Guiraud M., et al. Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-released structure and apolipoprotein A-I. Immunity 22 (2005) 71-80
    • (2005) Immunity , vol.22 , pp. 71-80
    • Scotet, E.1    Martinez, L.O.2    Grant, E.3    Barbaras, R.4    Jeno, P.5    Guiraud, M.6
  • 96
    • 33748131230 scopus 로고    scopus 로고
    • Human Vgamma9Vdelta2 T cells: promising new leads for immunotherapy of infections and tumors
    • Bonneville M., and Scotet E. Human Vgamma9Vdelta2 T cells: promising new leads for immunotherapy of infections and tumors. Curr. Opin. Immunol. 18 (2006) 539-546
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 539-546
    • Bonneville, M.1    Scotet, E.2
  • 97
    • 0034663731 scopus 로고    scopus 로고
    • Cell surface receptors and their ligands: in vitro analysis of CD6-CD166 interactions
    • Bowen M.A., Aruffo A.A., and Bajorath J. Cell surface receptors and their ligands: in vitro analysis of CD6-CD166 interactions. Proteins 40 (2000) 420-428
    • (2000) Proteins , vol.40 , pp. 420-428
    • Bowen, M.A.1    Aruffo, A.A.2    Bajorath, J.3
  • 98
    • 0033898112 scopus 로고    scopus 로고
    • Activated leukocyte cell adhesion molecule/CD166, a marker of tumor progression in primary malignant melanoma of the skin
    • van Kempen L.C., van den Oord J.J., van Muijen G.N., et al. Activated leukocyte cell adhesion molecule/CD166, a marker of tumor progression in primary malignant melanoma of the skin. Am. J. Pathol. 156 (2000) 769-774
    • (2000) Am. J. Pathol. , vol.156 , pp. 769-774
    • van Kempen, L.C.1    van den Oord, J.J.2    van Muijen, G.N.3
  • 99
    • 8444241199 scopus 로고    scopus 로고
    • ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival
    • Weichert W., Knosel T., Bellach J., Dietel M., and Kristiansen G. ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival. J. Clin. Pathol. 57 (2004) 1160-1164
    • (2004) J. Clin. Pathol. , vol.57 , pp. 1160-1164
    • Weichert, W.1    Knosel, T.2    Bellach, J.3    Dietel, M.4    Kristiansen, G.5
  • 100
    • 13844253776 scopus 로고    scopus 로고
    • Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival
    • Kristiansen G., Pilarsky C., Wissmann C., et al. Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival. J. Pathol. 205 (2005) 359-376
    • (2005) J. Pathol. , vol.205 , pp. 359-376
    • Kristiansen, G.1    Pilarsky, C.2    Wissmann, C.3
  • 101
  • 102
    • 0034719507 scopus 로고    scopus 로고
    • Coordinate recruitment of E-cadherin and ALCAM to cell-cell contacts by alpha-catenin
    • Tomita K., van Bokhoven A., Jansen C.F., et al. Coordinate recruitment of E-cadherin and ALCAM to cell-cell contacts by alpha-catenin. Biochem. Biophys. Res. Commun. 267 (2000) 870-874
    • (2000) Biochem. Biophys. Res. Commun. , vol.267 , pp. 870-874
    • Tomita, K.1    van Bokhoven, A.2    Jansen, C.F.3
  • 103
    • 33745852256 scopus 로고    scopus 로고
    • Involvement of CD166 in the activation of human gamma delta t cells by tumor cells sensitized with nonpeptide antigens
    • Kato Y., Tanaka Y., Hayashi M., Okawa K., and Minato N. Involvement of CD166 in the activation of human gamma delta t cells by tumor cells sensitized with nonpeptide antigens. J. Immunol. 177 (2006) 877-884
    • (2006) J. Immunol. , vol.177 , pp. 877-884
    • Kato, Y.1    Tanaka, Y.2    Hayashi, M.3    Okawa, K.4    Minato, N.5
  • 105
    • 0036467422 scopus 로고    scopus 로고
    • Lack of CD45RA-CD27-Vγ9Vδ2+ T cell effectors in immunocompromised hosts and during active pulmonary tuberculosis
    • Gioia C., Agrati C., Casetti R., et al. Lack of CD45RA-CD27-Vγ9Vδ2+ T cell effectors in immunocompromised hosts and during active pulmonary tuberculosis. J. Immunol. 168 (2002) 1484-1489
    • (2002) J. Immunol. , vol.168 , pp. 1484-1489
    • Gioia, C.1    Agrati, C.2    Casetti, R.3
  • 107
    • 30444431620 scopus 로고    scopus 로고
    • Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway
    • Thompson K., Rojas-Navea J., and Rogers M.J. Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway. Blood 107 (2006) 651-654
    • (2006) Blood , vol.107 , pp. 651-654
    • Thompson, K.1    Rojas-Navea, J.2    Rogers, M.J.3
  • 108
    • 0035917560 scopus 로고    scopus 로고
    • The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel
    • Jagdev S.P., Coleman R.E., Shipman C.M., Rostami H.A., and Croucher P.I. The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel. Br. J. Cancer 84 (2001) 1126-1134
    • (2001) Br. J. Cancer , vol.84 , pp. 1126-1134
    • Jagdev, S.P.1    Coleman, R.E.2    Shipman, C.M.3    Rostami, H.A.4    Croucher, P.I.5
  • 109
    • 11144254409 scopus 로고    scopus 로고
    • Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells
    • Neville-Webbe H.L., Rostami-Hodjegan A., Evans C.A., Coleman R.E., and Holen I. Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells. Int. J. Cancer 113 (2005) 364-371
    • (2005) Int. J. Cancer , vol.113 , pp. 364-371
    • Neville-Webbe, H.L.1    Rostami-Hodjegan, A.2    Evans, C.A.3    Coleman, R.E.4    Holen, I.5
  • 110
    • 33646107396 scopus 로고    scopus 로고
    • Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro
    • Neville-Webbe H.L., Evans C.A., Coleman R.E., and Holen I. Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro. Tumour Biol. 27 (2006) 92-103
    • (2006) Tumour Biol. , vol.27 , pp. 92-103
    • Neville-Webbe, H.L.1    Evans, C.A.2    Coleman, R.E.3    Holen, I.4
  • 111
    • 24044553904 scopus 로고    scopus 로고
    • Combined effects of zoledronic acid and doxorubicin on breast cancer cell invasion in vitro
    • Woodward J.K.L., Neville-Webbe H.L., Coleman R.E., and Holen I. Combined effects of zoledronic acid and doxorubicin on breast cancer cell invasion in vitro. Anticancer Drugs 16 (2005) 845-854
    • (2005) Anticancer Drugs , vol.16 , pp. 845-854
    • Woodward, J.K.L.1    Neville-Webbe, H.L.2    Coleman, R.E.3    Holen, I.4
  • 112
    • 33644534205 scopus 로고    scopus 로고
    • Taxanes and COX-2 inhibitors: from molecular pathways to clinical practice
    • Olsen S.R. Taxanes and COX-2 inhibitors: from molecular pathways to clinical practice. Biomed. Pharmacother. 59 Suppl 2 (2005) 306-310
    • (2005) Biomed. Pharmacother. , vol.59 , Issue.SUPPL. 2 , pp. 306-310
    • Olsen, S.R.1
  • 113
    • 0043075946 scopus 로고    scopus 로고
    • Effect of the combination of docetaxel, zoledronic acid, and a COX-2 inhibitor on the growth of human breast cancer cells
    • Witters L.M., Crispino J., Fraterrigo T., Green J., and Lipton A. Effect of the combination of docetaxel, zoledronic acid, and a COX-2 inhibitor on the growth of human breast cancer cells. Am. J. Clin. Oncol. 26 (2003) 92-97
    • (2003) Am. J. Clin. Oncol. , vol.26 , pp. 92-97
    • Witters, L.M.1    Crispino, J.2    Fraterrigo, T.3    Green, J.4    Lipton, A.5
  • 114
    • 33846523379 scopus 로고    scopus 로고
    • Combined effects of a third-generation bisphosphonate, zoledronic acid with other anticancer agents against murine osteosarcoma
    • Horie N., Murata H., Kimura S., Takeshita H., Sakabe T., Matsui T., et al. Combined effects of a third-generation bisphosphonate, zoledronic acid with other anticancer agents against murine osteosarcoma. Br. J. Cancer 96 (2007) 255-261
    • (2007) Br. J. Cancer , vol.96 , pp. 255-261
    • Horie, N.1    Murata, H.2    Kimura, S.3    Takeshita, H.4    Sakabe, T.5    Matsui, T.6
  • 115
    • 34047129164 scopus 로고    scopus 로고
    • Growth inhibition and sensitization to cisplatin by zoledronic acid in osteosarcoma cells
    • Benassi M.S., Chiechi A., Ponticelli F., Pazzaglia L., Gamberi G., and Zanella L. Growth inhibition and sensitization to cisplatin by zoledronic acid in osteosarcoma cells. Cancer Lett. 250 (2007) 194-205
    • (2007) Cancer Lett. , vol.250 , pp. 194-205
    • Benassi, M.S.1    Chiechi, A.2    Ponticelli, F.3    Pazzaglia, L.4    Gamberi, G.5    Zanella, L.6
  • 116
    • 0012371180 scopus 로고    scopus 로고
    • Synergistic growth inhibition of YM529 with biologic response modifiers (BRMs) in myeloma cells
    • Yata K., Otsuki T., Yamada O., Wada H., Yawata Y., and Sugihara T. Synergistic growth inhibition of YM529 with biologic response modifiers (BRMs) in myeloma cells. Int. J. Hematol. 75 (2002) 534-539
    • (2002) Int. J. Hematol. , vol.75 , pp. 534-539
    • Yata, K.1    Otsuki, T.2    Yamada, O.3    Wada, H.4    Yawata, Y.5    Sugihara, T.6
  • 117
    • 16544368557 scopus 로고    scopus 로고
    • Effects of an HMG-CoA reductase inhibitor, simvastatin, on human myeloma cells
    • Otsuki T., Sakaguchi H., Hatayama T., Fujii T., Tsujioka T., Sugihara T., et al. Effects of an HMG-CoA reductase inhibitor, simvastatin, on human myeloma cells. Oncol. Rep. 11 (2004) 1053-1058
    • (2004) Oncol. Rep. , vol.11 , pp. 1053-1058
    • Otsuki, T.1    Sakaguchi, H.2    Hatayama, T.3    Fujii, T.4    Tsujioka, T.5    Sugihara, T.6
  • 118
    • 19844367157 scopus 로고    scopus 로고
    • Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells
    • Cafforio P., Dammacco F., Gernone A., and Silvestris F. Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells. Carcinogenesis 26 (2005) 883-891
    • (2005) Carcinogenesis , vol.26 , pp. 883-891
    • Cafforio, P.1    Dammacco, F.2    Gernone, A.3    Silvestris, F.4
  • 120
    • 0141790853 scopus 로고    scopus 로고
    • The third-generation bisphosphonate zoledronate synergistically augments the anti-Ph+ leukemia activity of imatinib mesylate
    • Kuroda J., Kimura S., Segawa H., Kobayashi Y., Yoshikawa T., Urasaki Y., et al. The third-generation bisphosphonate zoledronate synergistically augments the anti-Ph+ leukemia activity of imatinib mesylate. Blood 102 (2003) 2229-2235
    • (2003) Blood , vol.102 , pp. 2229-2235
    • Kuroda, J.1    Kimura, S.2    Segawa, H.3    Kobayashi, Y.4    Yoshikawa, T.5    Urasaki, Y.6
  • 121
    • 0842278680 scopus 로고    scopus 로고
    • Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines
    • Kimura S., Kuroda J., Segawa H., Sato K., Nogawa M., Yuasa T., Ottmann O.G., and Maekawa T. Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines. Int. J. Hematol. 79 (2004) 37-43
    • (2004) Int. J. Hematol. , vol.79 , pp. 37-43
    • Kimura, S.1    Kuroda, J.2    Segawa, H.3    Sato, K.4    Nogawa, M.5    Yuasa, T.6    Ottmann, O.G.7    Maekawa, T.8
  • 122
    • 4644228513 scopus 로고    scopus 로고
    • The farnesyl transferase inhibitor R115777 (Zarnestras) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate
    • Caraglia M., D'Alessandro A.M., Marra M., Giuberti G., Vitale G., Viscomi C., et al. The farnesyl transferase inhibitor R115777 (Zarnestras) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate. Oncogene 23 (2004) 6900-6913
    • (2004) Oncogene , vol.23 , pp. 6900-6913
    • Caraglia, M.1    D'Alessandro, A.M.2    Marra, M.3    Giuberti, G.4    Vitale, G.5    Viscomi, C.6
  • 123
    • 0034777538 scopus 로고    scopus 로고
    • Protein farnesylation in mammalian cells: effects of farnesyltransferase inhibitors on cancer cells
    • Tamanoi F., Gau C.-L., Jiang C., Edamatsu H., and Kato-Stankiewicz J. Protein farnesylation in mammalian cells: effects of farnesyltransferase inhibitors on cancer cells. Cell. Mol. Life Sci. 58 (2001) 1636-1649
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 1636-1649
    • Tamanoi, F.1    Gau, C.-L.2    Jiang, C.3    Edamatsu, H.4    Kato-Stankiewicz, J.5
  • 124
    • 0042338751 scopus 로고    scopus 로고
    • Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer
    • Hiraga T., Ueda A., Tamura D., Hata K., Ikeda F., Williams P.J., et al. Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer. Int. J. Cancer 106 (2003) 973-979
    • (2003) Int. J. Cancer , vol.106 , pp. 973-979
    • Hiraga, T.1    Ueda, A.2    Tamura, D.3    Hata, K.4    Ikeda, F.5    Williams, P.J.6
  • 125
    • 10744227995 scopus 로고    scopus 로고
    • Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases
    • Uehara H., Kim S.J., Karashima T., Shepherd D.L., Fan D., Tsan R., et al. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. J. Natl. Cancer Inst. 95 (2003) 558-570
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 558-570
    • Uehara, H.1    Kim, S.J.2    Karashima, T.3    Shepherd, D.L.4    Fan, D.5    Tsan, R.6
  • 126
    • 18144394677 scopus 로고    scopus 로고
    • Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer
    • Kim S.J., Uehara H., Yazici S., He J., Langley R.R., Mathew P., et al. Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer. Cancer Res. 65 (2005) 3707-3715
    • (2005) Cancer Res. , vol.65 , pp. 3707-3715
    • Kim, S.J.1    Uehara, H.2    Yazici, S.3    He, J.4    Langley, R.R.5    Mathew, P.6
  • 127
    • 20544442197 scopus 로고    scopus 로고
    • Enhanced tumor regression and tissue repair when zoledronic acid is combined with ifosfamide in rat osteosarcoma
    • Heymann D., Ory B., Blanchard F., Heymann M.F., Coipeau P., Charrier C., et al. Enhanced tumor regression and tissue repair when zoledronic acid is combined with ifosfamide in rat osteosarcoma. Bone 37 (2005) 74-86
    • (2005) Bone , vol.37 , pp. 74-86
    • Heymann, D.1    Ory, B.2    Blanchard, F.3    Heymann, M.F.4    Coipeau, P.5    Charrier, C.6
  • 128
    • 25144456440 scopus 로고    scopus 로고
    • Effect of combination therapy with a novel bisphosphonate, minodronate (YM529), and docetaxel on a model of bone metastasis by human transitional cell carcinoma
    • Inoue K., Karashima T., Fukata S., Nomura A., Kawada C., Kurabayashi A., et al. Effect of combination therapy with a novel bisphosphonate, minodronate (YM529), and docetaxel on a model of bone metastasis by human transitional cell carcinoma. Clin. Cancer Res. 11 (2005) 6669-6677
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6669-6677
    • Inoue, K.1    Karashima, T.2    Fukata, S.3    Nomura, A.4    Kawada, C.5    Kurabayashi, A.6
  • 129
    • 29144521942 scopus 로고    scopus 로고
    • Zoledronic acid cooperates with a cyclooxygenase-2 inhibitor and gefitinib in inhibiting breast and prostate cancer
    • Melisi D., Caputo R., Damiano V., Bianco R., Veneziani B.M., Bianco A.R., et al. Zoledronic acid cooperates with a cyclooxygenase-2 inhibitor and gefitinib in inhibiting breast and prostate cancer. Endocr. Relat. Cancer 12 (2005) 1051-1058
    • (2005) Endocr. Relat. Cancer , vol.12 , pp. 1051-1058
    • Melisi, D.1    Caputo, R.2    Damiano, V.3    Bianco, R.4    Veneziani, B.M.5    Bianco, A.R.6
  • 130
    • 0037386939 scopus 로고    scopus 로고
    • Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect
    • Tortora G., Caputo R., Damiano V., Melisi D., Bianco R., Fontanini G., et al. Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect. Clin. Cancer Res. 9 (2003) 1566-1572
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1566-1572
    • Tortora, G.1    Caputo, R.2    Damiano, V.3    Melisi, D.4    Bianco, R.5    Fontanini, G.6
  • 131
    • 24944565348 scopus 로고    scopus 로고
    • Zoledronate synergises with imatinib mesylate to inhibit Ph+ primary leukaemic cell growth
    • Segawa H., Kimura S., Kuroda J., Sato K., Yokota A., Kawata E., et al. Zoledronate synergises with imatinib mesylate to inhibit Ph+ primary leukaemic cell growth. Br. J. Haematol. 130 (2005) 558-560
    • (2005) Br. J. Haematol. , vol.130 , pp. 558-560
    • Segawa, H.1    Kimura, S.2    Kuroda, J.3    Sato, K.4    Yokota, A.5    Kawata, E.6
  • 132
    • 34648866352 scopus 로고    scopus 로고
    • Synergistic effects of cytotoxic drugs and anti-resorptive agents in vitro and in vivo
    • Ottewell P.D., Jones M., Coleman R.E., and Holen I. Synergistic effects of cytotoxic drugs and anti-resorptive agents in vitro and in vivo. Breast Cancer Res. 100 S1 (2006) 5290
    • (2006) Breast Cancer Res. , vol.100 , Issue.SUPPL.1 , pp. 5290
    • Ottewell, P.D.1    Jones, M.2    Coleman, R.E.3    Holen, I.4
  • 133
    • 0034062815 scopus 로고    scopus 로고
    • American society of clinical oncology guideline on the role of bisphosphonates in breast cancer
    • Hillner B.E., Ingle J.N., Berenson J.R., Janjan N.A., Albain K.S., Lipton A., et al. American society of clinical oncology guideline on the role of bisphosphonates in breast cancer. J. Clin. Oncol. 18 (2000) 1378-1391
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1378-1391
    • Hillner, B.E.1    Ingle, J.N.2    Berenson, J.R.3    Janjan, N.A.4    Albain, K.S.5    Lipton, A.6
  • 134
    • 24744468646 scopus 로고    scopus 로고
    • Interference with the microenvironmental support impairs the de novo formation of bone metastases in vivo
    • van der Pluijm G., Que I., Sijmons B., Buijs J.T., Lowik C.W., Wetterwald A., et al. Interference with the microenvironmental support impairs the de novo formation of bone metastases in vivo. Cancer Res. 65 (2005) 7682-7690
    • (2005) Cancer Res. , vol.65 , pp. 7682-7690
    • van der Pluijm, G.1    Que, I.2    Sijmons, B.3    Buijs, J.T.4    Lowik, C.W.5    Wetterwald, A.6
  • 135
    • 28844466044 scopus 로고    scopus 로고
    • HTLV-1 Tax transgenic mice develop spontaneous osteolytic bone metastases prevented by osteoclast inhibition
    • Gao L., Deng H., Zhao H., Hirbe A., Harding J., Ratner L., and Weilbaecher K. HTLV-1 Tax transgenic mice develop spontaneous osteolytic bone metastases prevented by osteoclast inhibition. Blood 106 (2005) 4294-4302
    • (2005) Blood , vol.106 , pp. 4294-4302
    • Gao, L.1    Deng, H.2    Zhao, H.3    Hirbe, A.4    Harding, J.5    Ratner, L.6    Weilbaecher, K.7
  • 136
    • 0037687355 scopus 로고    scopus 로고
    • Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of intergroup trial C9741/Cancer and leukemia group B trial 9741
    • Citron M.L., Berry D.A., Cirrincione C., Hudis C., Winer E.P., Gradishar W.J., et al. Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of intergroup trial C9741/Cancer and leukemia group B trial 9741. J. Clin. Oncol. 21 (2003) 1431-1439
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1431-1439
    • Citron, M.L.1    Berry, D.A.2    Cirrincione, C.3    Hudis, C.4    Winer, E.P.5    Gradishar, W.J.6
  • 137
    • 0034214362 scopus 로고    scopus 로고
    • Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
    • Boissier S., Ferreras M., Peyruchaud O., Magnetto S., Ebetino F.H., Colombel M., et al. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. Cancer Res. 60 (2000) 2949-2954
    • (2000) Cancer Res. , vol.60 , pp. 2949-2954
    • Boissier, S.1    Ferreras, M.2    Peyruchaud, O.3    Magnetto, S.4    Ebetino, F.H.5    Colombel, M.6
  • 138
    • 85056023563 scopus 로고    scopus 로고
    • The direct antitumour activity of bisphosphonates in vivo depends on their bone mineral affinity
    • Fournier P., Daubiné F., Lundy M.W., Ebetino F.H., and Clézardin P. The direct antitumour activity of bisphosphonates in vivo depends on their bone mineral affinity. Bone 38 (2006) S45
    • (2006) Bone , vol.38
    • Fournier, P.1    Daubiné, F.2    Lundy, M.W.3    Ebetino, F.H.4    Clézardin, P.5
  • 139
    • 33746926292 scopus 로고    scopus 로고
    • Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach
    • Zeisberger S.M., Odermatt B., Marty C., Zehnder-Fjällman A.H.M., Ballmer-Hofer K., and Schwendener R.A. Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach. Br. J. Cancer 95 (2006) 272-281
    • (2006) Br. J. Cancer , vol.95 , pp. 272-281
    • Zeisberger, S.M.1    Odermatt, B.2    Marty, C.3    Zehnder-Fjällman, A.H.M.4    Ballmer-Hofer, K.5    Schwendener, R.A.6
  • 140
    • 16544379650 scopus 로고    scopus 로고
    • Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid
    • Vogt U., Bielawski K.P., Bosse U., and Schlotter C.M. Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid. Oncol. Rep. 12 (2004) 1109-1114
    • (2004) Oncol. Rep. , vol.12 , pp. 1109-1114
    • Vogt, U.1    Bielawski, K.P.2    Bosse, U.3    Schlotter, C.M.4
  • 141
    • 27144522528 scopus 로고    scopus 로고
    • Additive/synergistic antitumoral effects on prostate cancer cells in vitro following treatment with a combination of docetaxel and zoledronic acid
    • Ullen A., Lennartsson L., Harmenberg U., Hjelm-Eriksson M., Kalkner K.M., Lennernas B., and Nilsson S. Additive/synergistic antitumoral effects on prostate cancer cells in vitro following treatment with a combination of docetaxel and zoledronic acid. Acta Oncol. 44 (2005) 644-650
    • (2005) Acta Oncol. , vol.44 , pp. 644-650
    • Ullen, A.1    Lennartsson, L.2    Harmenberg, U.3    Hjelm-Eriksson, M.4    Kalkner, K.M.5    Lennernas, B.6    Nilsson, S.7
  • 142
    • 33646783320 scopus 로고    scopus 로고
    • Zoledronic acid (Zometa) enhances the cytotoxic effect of gemcitabine and fluvastatin: in vitro isobologram studies with conventional and nonconventional cytotoxic agents
    • Budman D.R., and Calabro A. Zoledronic acid (Zometa) enhances the cytotoxic effect of gemcitabine and fluvastatin: in vitro isobologram studies with conventional and nonconventional cytotoxic agents. Oncology 70 (2006) 147-153
    • (2006) Oncology , vol.70 , pp. 147-153
    • Budman, D.R.1    Calabro, A.2
  • 143
    • 0034055664 scopus 로고    scopus 로고
    • Growth inhibition and synergistic induction of apoptosis by zoledronate and dexamethasone in human myeloma cell lines
    • Tassone P., Forciniti S., Galea E., Morrone G., Turco M.C., Martinelli V., Tagliaferri P., and Venuta S. Growth inhibition and synergistic induction of apoptosis by zoledronate and dexamethasone in human myeloma cell lines. Leukemia 14 (2000) 841-844
    • (2000) Leukemia , vol.14 , pp. 841-844
    • Tassone, P.1    Forciniti, S.2    Galea, E.3    Morrone, G.4    Turco, M.C.5    Martinelli, V.6    Tagliaferri, P.7    Venuta, S.8


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