Inhibitors of Bcl-2 protein family deplete ER Ca2+ stores in pancreatic acinar cells

Pflugers Archiv European Journal of Physiology

Volumn 460, Issue 5, 2010, Pages 891-900

  Gerasimenko, Julia ^c,d   Ferdek, Pawel ^c   Fischer, Lars ^a,b   Gukovskaya, Anna S ^a,b   Pandol, Stephen J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Acetylcholine; Cell death; Pancreas; Pancreatic acinar cell; Signal transduction; Transport

Indexed keywords

3 IODO 5 CHLORO N [2 CHLORO 5 (4 CHLOROPHENYL)SULPHONYL]PHENYL 2 HYDROXYBENZAMIDE; CALCIUM ION; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN INHIBITOR; RYANODINE RECEPTOR; UNCLASSIFIED DRUG;

ACINAR CELL; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM INDUCED CALCIUM RELEASE; CALCIUM TRANSPORT; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROFLUOROMETRY; GENE OVEREXPRESSION; MICROFLUOROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; RAT;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BENZAMIDES; BENZOPYRANS; CALCIUM; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; MICE; NITRILES; PANCREAS, EXOCRINE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 77957916106     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-010-0859-4     Document Type: Article

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