Hepatic gene expression profiling reveals key pathways involved in leptin-mediated weight loss in ob/ob mice

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Sharma, Ashok ^a   Bartell, Shoshana M ^b   Baile, Clifton A ^b   Chen, Bo ^a   Podolsky, Robert H ^a   McIndoe, Richard A ^a   She, Jin Xiong ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; ACYL COENZYME A DESATURASE; ADENOSYLHOMOCYSTEINASE; CARBOXYLIC ACID; CARRIER PROTEIN; COMPLEMENT COMPONENT C1; CYTOCHROME P450 17; DIMETHYLGLYCINE DEHYDROGENASE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUTATHIONE TRANSFERASE; HEPCIDIN; HLA ANTIGEN CLASS 2; IRON DERIVATIVE; LEPTIN; LIPOPROTEIN LIPASE; LYSOZYME; METHIONINE ADENOSYLTRANSFERASE; NICOTINAMIDE METHYLTRANSFERASE; PALMITOYL COENZYME A HYDROLASE; PHOSPHOLIPASE A2; RETINOL DEHYDROGENASE; RIBOSOME PROTEIN; RIBOSOME PROTEIN S11; SARCOSINE DEHYDROGENASE; SELENIUM BINDING PROTEIN; SIGMA OPIATE RECEPTOR; SMALL NUCLEOLAR RNA; SOLUTE CARRIER FAMILY 40 MEMBER 1; SOMATOMEDIN BINDING PROTEIN 2; UNCLASSIFIED DRUG; INSULIN; IRON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATABOLISM; CELL VACUOLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DECREASED APPETITE; DOWN REGULATION; ENDOPLASMIC RETICULUM; FEMALE; FOOD INTAKE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE LOCATION; GENE OVEREXPRESSION; HYPOTHALAMUS FUNCTION; INFLAMMATION; LIPID METABOLISM; LIPOGENESIS; LIVER; LIVER LYSOSOME; MICROARRAY ANALYSIS; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NEUROTRANSMISSION; NONHUMAN; OBESITY; SIGNAL TRANSDUCTION; UPREGULATION; WEIGHT REDUCTION; ADIPOCYTE; ANIMAL; BLOOD; BODY WEIGHT; CELL DIFFERENTIATION; CELL PROLIFERATION; CLUSTER ANALYSIS; DNA MICROARRAY; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; EATING; GENETICS; HYPOTHALAMUS; IMMUNOLOGY; LYSOSOME; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

MUS;

ADIPOCYTES; ANIMALS; BODY WEIGHT; CARBOXYLIC ACIDS; CELL DIFFERENTIATION; CELL PROLIFERATION; CLUSTER ANALYSIS; DOWN-REGULATION; DRUG ADMINISTRATION ROUTES; EATING; FEMALE; GENE EXPRESSION PROFILING; GLUTATHIONE TRANSFERASE; HYPOTHALAMUS; INFLAMMATION; INSULIN; IRON; LEPTIN; LIPID METABOLISM; LIVER; LYSOSOMES; MICE; MITOCHONDRIA; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; WEIGHT LOSS;

EID: 77957910018     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012147     Document Type: Article

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