Investigation of 4-piperidinols as novel H3 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 21, 2010, Pages 6246-6249

  Anderson, James T ^a   Campbell, Michael ^a   Wang, Jianmin ^a   Brunden, Kurt R ^a   Harrington, John J ^a   Stricker Krongrad, Alain ^a   Song, Jianping ^a   Doucette, Chris ^a   Murphy, Steven ^a   Bennani, Youssef L ^a  

^a ATHERSYS INC   (United States)

Author keywords

Antagonist; CNS; G protein coupled receptor; H3; Histamine; Piperidinol

Indexed keywords

CLOBENPROPIT; HISTAMINE H3 RECEPTOR ANTAGONIST; JNJ 5207852; PIPERIDONE DERIVATIVE; POTASSIUM CHANNEL HERG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG BINDING; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; ETHER-A-GO-GO POTASSIUM CHANNELS; HISTAMINE H3 ANTAGONISTS; HUMANS; INDICATORS AND REAGENTS; MICE; MODELS, MOLECULAR; PIPERIDINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77957867641     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.08.099     Document Type: Article

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