Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 37, 2006, Pages 13866-13871

  Yoshimoto, Ryo ^a   Miyamoto, Yasuhisa ^a   Shimamura, Ken ^a   Ishihara, Akane ^a   Takahashi, Kazuhiko ^a   Kotani, Hidehito ^a   Chen, Airu S ^b   Chen, Howard Y ^b   MacNeil, Douglas J ^b   Kanatani, Akio ^a   Tokita, Shigeru ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Appetite regulation; Autoreceptor; Heteroreceptor

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 5 HYDROXYINDOLEACETIC ACID; ALPHA FLUOROMETHYLHISTIDINE; ANTIDIABETIC AGENT; ANTIOBESITY AGENT; DOPAMINE; HISTAMINE H3 RECEPTOR AGONIST; HISTAMINE SYNTHESIS INHIBITOR; HOMOVANILLIC ACID; IMETIT; INSULIN DERIVATIVE; LEPTIN; LIGAND; MELANOCORTIN; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; NORADRENALIN; NORMETADRENALIN; SEROTONIN; THIOPERAMIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APPETITE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY BALANCE; FOOD INTAKE; HISTAMINE METABOLISM; HISTAMINE RELEASE; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TREATMENT RESPONSE;

ANIMALS; APPETITE; BODY WEIGHT; DIABETES MELLITUS; HISTAMINE AGONISTS; IMIDAZOLES; INSULIN; LEPTIN; MICE; MICE, KNOCKOUT; OBESITY; PIPERIDINES; RECEPTORS, HISTAMINE H3; THIOUREA;

EID: 33748793665     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0506104103     Document Type: Article

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