Acute Myocardial Rescue with Endogenous Endothelial Progenitor Cell Therapy

Heart Lung and Circulation

Volumn 19, Issue 11, 2010, Pages 644-654

  Atluri, Pavan ^a   Panlilio, Corinna M ^a   Liao, George P ^a   Hiesinger, William ^a   Harris, David Andrew ^a   McCormick, Ryan C ^a   Cohen, Jeffrey E ^a   Jin, Tao ^a   Feng, Wei ^a   Levit, Rebecca D ^a   Dong, Nianguo ^a   Woo, Y Joseph ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Endothelial progenitor cell; Granulocyte macrophage colony stimulating factor; Ischaemia; Stromal cell derived factor; Vasculogenesis

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; SODIUM CHLORIDE; STROMAL CELL DERIVED FACTOR 1ALPHA;

ACUTE HEART INFARCTION; ANGIOCARDIOGRAPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; FLOW CYTOMETRY; HEART EJECTION FRACTION; HEART HEMODYNAMICS; HEART MUSCLE PERFUSION; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE SIZE; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LEWIS RAT; LYMPHOCYTE COUNT; MALE; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL TRANSPLANTATION; UPREGULATION;

ANIMALS; APOPTOSIS; CHEMOKINE CXCL12; ECHOCARDIOGRAPHY; ENDOTHELIAL CELLS; FLOW CYTOMETRY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEART; HEART VENTRICLES; HEMATOPOIETIC STEM CELLS; HEMODYNAMICS; MALE; MODELS, ANIMAL; MYOCARDIAL INFARCTION; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, INBRED LEW; UP-REGULATION; VENTRICULAR FUNCTION, LEFT;

EID: 77957861502     PISSN: 14439506     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hlc.2010.06.1056     Document Type: Article

References (47)

1. Boodhwani M., Sodha N.R., Laham R.J., Sellke F.W. The future of therapeutic myocardial angiogenesis. Shock 2006, 26(4):332-341.
2. Assmus B., Schachinger V., Teupe C., Britten M., Lehmann R., Dobert N., Grunwald F., Aicher A., Urbich C., Martin H., Hoelzer D., Dimmeler S., Zeiher A.M. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 2002, 24(106):3009-3017.
3. Woo Y.J., Grand T.J., Berry M.F., Atluri P., Moise M.A., Hsu V.M., Cohen J., Fisher O., Burdick J., Taylor M., Zentko S., Liao G., Smith M., Kolakowski S., Jayasankar V., Gardner T.J., Sweeney H.L. Stromal cell-derived factor and granulocyte-monocyte colony-stimulating factor form a combined neovasculogenic therapy for ischemic cardiomyopathy. The Journal of Thoracic and Cardiovascular Surgery 2005, 130(August (2)):321-329.
4. Numaguchi Y., Sone T., Okumura K., Ishii M., Morita Y., Kubota R., Yokouchi K., Imai H., Harada M., Osanai H., Kondo T., Murohara T. The impact of the capability of circulating progenitor cell to differentiate on myocardial salvage in patients with primary acute myocardial infarction. Circulation 2006, 114(1 Suppl.):I114-119.
5. Simons M. Angiogenesis: where do we stand now?. Circulation 2005, 111(12):1556-1566.
6. Kocher A.A., Schuster M.D., Szabolcs M.J., Takuma S., Burkhoff D., Wang J., Homma S., Edwards N.M., Itescu S. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nature Medicine 2001, 7(April (4)):430-436.
7. Ceradini D.J., Kulkarni A.R., Callaghan M.J., Tepper O.M., Bastidas N., Kleinman M.E., Capla J.M., Galiano R.D., Levine J.P., Gurtner G.C. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nature Medicine 2004, 10(August (8)):858-864.
8. Toyota E., Warltier D.C., Brock T., Ritman E., Kolz C., O'Malley P., Rocic P., Focardi M., Chilian W.M. Vascular endothelial growth factor is required for coronary collateral growth in the rat. Circulation 2005, 112(14):2108-2113.
9. Atluri P., Woo Y.J. Pro-angiogenic cytokines as cardiovascular therapeutics: assessing the potential. BioDrugs 2008, 22(4):209-222.
10. Assmus B., Honold J., Schachinger V., Britten M.B., Fischer-Rasokat U., Lehmann R., Teupe C., Pistorius K., Martin H., Abolmaali N.D., Tonn T., Dimmeler S., Zeiher A.M. Transcoronary transplantation of progenitor cells after myocardial infarction. The New England Journal of Medicine 2006, 355(12):1222-1232.
11. Huusko J., Merentie M., Dijkstra M.H., Ryhanen M.M., Karvinen H., Rissanen T.T., Vanwildemeersch M., Hedman M., Lipponen J., Heinonen S.E., Eriksson U., Shibuya M., Yla-Herttuala S. The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice. Cardiovascular Research 2009.
12. Zhu X.Y., Zhang X.Z., Xu L., Zhong X.Y., Ding Q., Chen Y.X. Transplantation of adipose-derived stem cells overexpressing hHGF into cardiac tissue. Biochemical and Biophysical Research Communications 2009, 379(4):1084-1090.
13. Elmadbouh I., Haider H., Jiang S., Idris N.M., Lu G., Ashraf M. Ex vivo delivered stromal cell-derived factor-1alpha promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium. Journal of Molecular and Cellular Cardiology 2007, 42(April (4)):792-803.
14. Mirshahi F., Pourtau J., Li H., Muraine M., Trochon V., Legrand E., Vannier J., Soria J., Vasse M., Soria C. SDF-1 activity on microvascular endothelial cells: consequences on angiogenesis in in vitro and in vivo models. Thrombosis Research 2000, 99(6):587-594.
15. Heeschen C., Lehmann R., Honold J., Assmus B., Aicher A., Walter D.H., Martin H., Zeiher A.M., Dimmeler S. Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation 2004, 109(13):1615-1622.
16. Schuh A., Liehn E.A., Sasse A., Hristov M., Sobota R., Kelm M., Merx M.W., Weber C. Transplantation of endothelial progenitor cells improves neovascularization and left ventricular function after myocardial infarction in a rat model. Basic Research in Cardiology 2008, 103(January (1)):69-77.
17. Li M., Yu J., Li Y., Li D., Yan D., Qu Z., Ruan Q. CXCR4 positive bone mesenchymal stem cells migrate to human endothelial cell stimulated by ox-LDL via SDF-1alpha/CXCR4 signaling axis. Experimental and Molecular Pathology 2009.
18. Yamaguchi J., Kusano K.F., Masuo O., Kawamoto A., Silver M., Murasawa S., Bosch-Marce M., Masuda H., Losordo D.W., Isner J.M., Asahara T. Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation 2003, 107(9):1322-1328.
19. Atluri P., Liao G.P., Panlilio C.M., Hsu V.M., Leskowitz M.J., Morine K.J., Cohen J.E., Berry M.F., Suarez E.E., Murphy D.A., Lee W.M., Gardner T.J., Sweeney H.L., Woo Y.J. Neovasculogenic therapy to augment perfusion and preserve viability in ischemic cardiomyopathy. The Annals of Thoracic Surgery 2006, 81(May (5)):1728-1736.
20. Abbott J.D., Huang Y., Liu D., Hickey R., Krause D.S., Giordano F.J. Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 2004, 110(21):3300-3305.
21. Jayasankar V., Pirolli T.J., Bish L.T., Berry M.F., Burdick J., Grand T., Woo Y.J. Targeted overexpression of growth hormone by adenoviral gene transfer preserves myocardial function and ventricular geometry in ischemic cardiomyopathy. Journal of Molecular and Cellular Cardiology 2004, 36(April (4)):531-538.
22. Liu Y.H., Yang X.P., Nass O., Sabbah H.N., Peterson E., Carretero O.A. Chronic heart failure induced by coronary artery ligation in Lewis inbred rats. The American Journal of Physiology 1997, 272(2 Pt 2):H722-727.
23. Jayasankar V., Woo Y.J., Bish L.T., Pirolli T.J., Chatterjee S., Berry M.F., Burdick J., Gardner T.J., Sweeney H.L. Gene transfer of hepatocyte growth factor attenuates postinfarction heart failure. Circulation 2003, 108(Suppl. 1):II230-236.
24. Woo Y.J., Panlilio C.M., Cheng R.K., Liao G.P., Atluri P., Hsu V.M., Cohen J.E., Chaudhry H.W. Therapeutic delivery of cyclin A2 induces myocardial regeneration and enhances cardiac function in ischemic heart failure. Circulation 2006, 114(1 Suppl.):I206-213.
25. Jayasankar V., Bish L.T., Pirolli T.J., Berry M.F., Burdick J., Woo Y.J. Local myocardial overexpression of growth hormone attenuates postinfarction remodeling and preserves cardiac function. The Annals of Thoracic Surgery 2004, 77(June (6)):2122-2129. [discussion 2129].
26. Morgan E.E., Faulx M.D., McElfresh T.A., Kung T.A., Zawaneh M.S., Stanley W.C., Chandler M.P., Hoit B.D. Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction. American Journal of Physiology-Heart and Circulatory Physiology 2004, 287(November (5)):H2049-2053.
27. Brown L., Fenning A., Chan V., Loch D., Wilson K., Anderson B., Burstow D. Echocardiographic assessment of cardiac structure and function in rats. Heart, Lung & Circulation 2002, 11(3):167-173.
28. Gee M.S., Procopio W.N., Makonnen S., Feldman M.D., Yeilding N.M., Lee W.M. Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy. The American Journal of Physiology 2003, 162(1):183-193.
29. Hristov M., Erl W., Weber P.C. Endothelial progenitor cells: mobilization, differentiation, and homing. Arteriosclerosis, Thrombosis, and Vascular Biology 2003, 23(7):1185-1189.
30. Rothe G., Barlage S., Schmitz G., Kloushe M. Flow cytometric assessment of haematopoietic stem and progenitor cells. Journal of Laboratory Medicine 2003, 27:175-181.
31. Marsboom G., Pokreisz P., Gheysens O., Vermeersch P., Gillijns H., Pellens M., Liu X., Collen D., Janssens S. Sustained endothelial progenitor cell dysfunction after chronic hypoxia-induced pulmonary hypertension. Stem Cells (Dayton, OH) 2008, 26(4):1017-1026.
32. Fazel S., Cimini M., Chen L., Li S., Angoulvant D., Fedak P., Verma S., Weisel R.D., Keating A., Li R.K. Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. The Journal of Clinical Investigation 2006, 116(July (7)):1865-1877.
33. Bagley R.G., Rouleau C., St Martin T., Boutin P., Weber W., Ruzek M., Honma N., Nacht M., Shankara S., Kataoka S., Ishida I., Roberts B.L., Teicher B.A. Human endothelial precursor cells express tumor endothelial marker 1/endosialin/CD248. Molecular Cancer Therapeutics 2008, 7(August (8)):2536-2546.
34. Braunwald E., Bristow M.R. Congestive heart failure: fifty years of progress. Circulation 2000, 102(20 Suppl. 4):IV14-23.
35. Benjamin I.J., Schneider M.D. Learning from failure: congestive heart failure in the postgenomic age. The Journal of Clinical Investigation 2005, 115(March (3)):495-499.
36. Canty J.M., Suzuki G., Banas M.D., Verheyen F., Borgers M., Fallavollita J.A. Hibernating myocardium: chronically adapted to ischemia but vulnerable to sudden death. Circulation Research 2004, 94(8):1142-1149.
37. Erbs S., Linke A., Adams V., Lenk K., Thiele H., Diederich K.W., Emmrich F., Kluge R., Kendziorra K., Sabri O., Schuler G., Hambrecht R. Transplantation of blood-derived progenitor cells after recanalization of chronic coronary artery occlusion: first randomized and placebo-controlled study. Circulation Research 2005, 97(8):756-762.
38. Perin E.C., Dohmann H.F., Borojevic R., Silva S.A., Sousa A.L., Mesquita C.T., Rossi M.I., Carvalho A.C., Dutra H.S., Dohmann H.J., Silva G.V., Belem L., Vivacqua R., Rangel F.O., Esporcatte R., Geng Y.J., Vaughn W.K., Assad J.A., Mesquita E.T., Willerson J.T. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation 2003, 107(18):2294-2302.
39. Britten M.B., Abolmaali N.D., Assmus B., Lehmann R., Honold J., Schmitt J., Vogl T.J., Martin H., Schachinger V., Dimmeler S., Zeiher A.M. Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging. Circulation 2003, 108(18):2212-2218.
40. Kawamoto A., Iwasaki H., Kusano K., Murayama T., Oyamada A., Silver M., Hulbert C., Gavin M., Hanley A., Ma H., Kearney M., Zak V., Asahara T., Losordo D.W. CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cells. Circulation 2006, 114(20):2163-2169.
41. Schachinger V., Erbs S., Elsasser A., Haberbosch W., Hambrecht R., Holschermann H., Yu J., Corti R., Mathey D.G., Hamm C.W., Suselbeck T., Assmus B., Tonn T., Dimmeler S., Zeiher A.M. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. The New England Journal of Medicine 2006, 355(12):1210-1221.
42. Powell T.M., Paul J.D., Hill J.M., Thompson M., Benjamin M., Rodrigo M., McCoy J.P., Read E.J., Khuu H.M., Leitman S.F., Finkel T., Cannon R.O. Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology 2005, 25(February (2)):296-301.
43. Schmidt-Lucke C., Rossig L., Fichtlscherer S., Vasa M., Britten M., Kamper U., Dimmeler S., Zeiher A.M. Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair. Circulation 2005, 111(22):2981-2987.
44. Hill J.M., Zalos G., Halcox J.P., Schenke W.H., Waclawiw M.A., Quyyumi A.A., Finkel T. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. The New England Journal of Medicine 2003, 348(7):593-600.
45. Walter D.H., Haendeler J., Reinhold J., Rochwalsky U., Seeger F., Honold J., Hoffmann J., Urbich C., Lehmann R., Arenzana-Seisdesdos F., Aicher A., Heeschen C., Fichtlscherer S., Zeiher A.M., Dimmeler S. Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease. Circulation Research 2005, 97(11):1142-1151.
46. Zhuo Y., Li S.H., Chen M.S., Wu J., McDonald Kinkaid H.Y., Fazel S., Weisel R.D., Li R.K. Aging impairs the angiogenic response to ischemic injury and the activity of implanted cells: combined consequences for cell therapy in older recipients. The Journal of Thoracic and Cardiovascular Surgery 2009.
47. Sodha N.R., Clements R.T., Boodhwani M., Xu S.H., Laham R.J., Bianchi C., Sellke F.W. Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation. American Journal of Physiology-Heart and Circulatory Physiology 2009, 296(February (2)):H428-434.