Legionnaires disease in cannabis smokers

Chest

Volumn 138, Issue 4, 2010, Pages 989-991

  Nguyen, Lan Tien ^a   Picard Bernard, Valérie ^b   Perriot, Jean ^c  

^a Service de Pneumologie   (France)

^b Service de Psychiatrie Adultes   (France)

^c Dispensaire Emile Roux   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABIS; DRONABINOL; LEVOFLOXACIN; OFLOXACIN; RIFAMPICIN;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; CANNABIS ADDICTION; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; HUMAN; IMMUNE RESPONSE; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; MALE; PRIORITY JOURNAL; RISK FACTOR; SMOKING;

EID: 77957842566     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.10-0410     Document Type: Article

References (20)

1. Ruiz M, Ewig S, Marcos MA, et al. Etiology of community-acquired pneumonia: impact of age, comorbidity, and severity. Am J Respir Crit Care Med. 1999;160(2):397-405. (Pubitemid 29380648)
2. Den Boer JW, Nijhof J, Friesema I. Risk factors for sporadic community-acquired Legionnaires' disease. A 3-year national case-control study. Public Health. 2006;120(6):566-571. (Pubitemid 43869386)
3. Che D, Campese C, Santa-Olalla P, et al. Sporadic community-acquired Legionnaires' disease in France: a 2-year national matched case-control study. Epidemiol Infect. 2008;136(12):1684-1690.
4. Bagaitkar J, Demuth DR, Scott DA. Tobacco use increases susceptibility to bacterial infection. Tob Induc Dis. 2008;4:12-22.
5. Klein TW, Newton C, Larsen K, et al. The cannabinoid system and immune modulation. J Leukoc Biol. 2003;74(4):486-496.
6. Barbers RG, Gong H Jr, Tashkin DP, Oishi J, Wallace JM. Differential examination of bronchoalveolar lavage cells in tobacco cigarette and marijuana smokers. Am Rev Respir Dis. 1987;135(6):1271-1275. (Pubitemid 18021520)
7. Baldwin GC, Tashkin DP, Buckley DM, Park AN, Dubinett SM, Roth MD. Marijuana and cocaine impair alveolar macrophage function and cytokine production. Am J Respir Crit Care Med. 1997;156(5):1606-1613.
8. Roth MD, Baldwin GC, Tashkin DP. Effects of delta-9-tetrahydrocannabinol on human immune function and host defense. Chem Phys Lipids. 2002;121(1-2):229-239.
9. Shay AH, Choi R, Whittaker K, et al. Impairment of antimicrobial activity and nitric oxide production in alveolar macrophages from smokers of marijuana and cocaine. J Infect Dis. 2003;187(4):700-704. (Pubitemid 36250038)
10. Tang JL, Lancz G, Specter S, Bullock H. Marijuana and immunity: tetrahydrocannabinol-mediated inhibition of growth and phagocytic activity of the murine macrophage cell line, P388D1. Int J Immunopharmacol. 1992;14(2):253-262.
11. Springs AE, Karmaus PW, Crawford RB, Kaplan BL, Kaminski NE. Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by Delta9-tetrahydrocannabinol. J Leukoc Biol. 2008;84(6):1574-1584.
12. Schatz AR, Koh WS, Kaminski NE. Delta-9-tetrahydrocannabinol selectively inhibits T-cell dependent humoral immune responses through direct inhibition of accessory T-cell function. Immunopharmacology. 1993;26(2):129-137.
13. Klein TW, Newton C, Friedman H. Inhibition of natural killer cell function by marijuana components. J Toxicol Environ Health. 1987;20(4):321-332. (Pubitemid 17059975)
14. McKallip RJ, Lombard C, Martin BR, Nagarkatti M, Nagarkatti PS. Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo. J Pharmacol Exp Ther. 2002;302(2):451-465. (Pubitemid 34787207)
15. Newton CA, Klein TW, Friedman H. Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection. Infect Immun. 1994;62(9):4015-4020. (Pubitemid 24264350)
16. Klein TW, Newton CA, Nakachi N, Friedman H. Delta 9-tetrahydrocannabinol treatment suppresses immunity and early IFN-gamma, IL-12, and IL-12 receptor beta 2 responses to Legionella pneumophila infection. J Immunol. 2000;164(12):6461-6466. (Pubitemid 30408829)
17. Lu T, Newton C, Perkins I, Friedman H, Klein TW. Cannabinoid treatment suppresses the T-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection. J Pharmacol Exp Ther. 2006;319(1):269-276. (Pubitemid 44455132)
18. Pacifici R, Zuccaro P, Pichini S, et al. Modulation of the immune system in cannabis users. JAMA. 2003;289(15):1929-1931. (Pubitemid 37430223)
19. Blander SJ, Horwitz MA. Vaccination with Legionella pneumophila membranes induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. Protective immunity independent of the major secretory protein of Legionella pneumophila. J Clin Invest. 1991;87(3):1054-1059.
20. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol. 1989;7:145-173.