-
1
-
-
0014684354
-
Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo
-
Fleisch H, Russell RG, Francis MD. Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science 1969; 165:1262-4.
-
(1969)
Science
, vol.165
, pp. 1262-1264
-
-
Fleisch, H.1
Russell, R.G.2
Francis, M.D.3
-
2
-
-
0030227986
-
Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones
-
Masarachia P, Weinreb M, Balena R, et al. Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones. Bone 1996; 19:281-90.
-
(1996)
Bone
, vol.19
, pp. 281-290
-
-
Masarachia, P.1
Weinreb, M.2
Balena, R.3
-
4
-
-
0029133135
-
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo
-
Hughes DE, Wright KR, Uy HL, et al. Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo. J Bone Miner Res 1995; 10:1478-87.
-
(1995)
J Bone Miner Res
, vol.10
, pp. 1478-1487
-
-
Hughes, D.E.1
Wright, K.R.2
Uy, H.L.3
-
5
-
-
0030601220
-
Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes
-
Rogers MJ, Brown RJ, Hodkin V, et al. Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes. Biochem Biophys Res Com-mun 1996; 224:863-9.
-
(1996)
Biochem Biophys Res Com-mun
, vol.224
, pp. 863-869
-
-
Rogers, M.J.1
Brown, R.J.2
Hodkin, V.3
-
6
-
-
0242503684
-
New insights into the molecular mechanisms of action of bisphosphonates
-
Rogers MJ. New insights into the molecular mechanisms of action of bisphosphonates. Curr Pharm Des 2003; 9:2643-58.
-
(2003)
Curr Pharm des
, vol.9
, pp. 2643-2658
-
-
Rogers, M.J.1
-
7
-
-
0031977199
-
Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
-
Luckman SP, Hughes DE, Coxon FP, et al. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res 1998; 13:581-9.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 581-589
-
-
Luckman, S.P.1
Hughes, D.E.2
Coxon, F.P.3
-
8
-
-
0033554651
-
Farnesyl pyrophosphate synthase is the mo-lecular target of nitrogen-containing bisphosphonates
-
van Beek E, Pieterman E, Cohen L, et al. Farnesyl pyrophosphate synthase is the mo-lecular target of nitrogen-containing bisphosphonates. Biochem Biophys Res Commun 1999; 264:108-11.
-
(1999)
Biochem Biophys Res Commun
, vol.264
, pp. 108-111
-
-
Van Beek, E.1
Pieterman, E.2
Cohen, L.3
-
9
-
-
13044283050
-
Alendronate mechanism of action: Geranyl-geraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
-
Fisher JE, Rogers MJ, Halasy JM, et al. Alendronate mechanism of action: geranyl-geraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro. Proc Natl Acad Sci USA 1999; 96:133-8.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 133-138
-
-
Fisher, J.E.1
Rogers, M.J.2
Halasy, J.M.3
-
10
-
-
0036148405
-
Development of bisphosphonates
-
Fleisch H. Development of bisphosphonates. Breast Cancer Res 2002; 4:30-4.
-
(2002)
Breast Cancer Res
, vol.4
, pp. 30-34
-
-
Fleisch, H.1
-
11
-
-
0035146537
-
Structure-activity relationships for inhibi-tion of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates
-
Dunford JE, Thompson K, Coxon FP, et al. Structure-activity relationships for inhibi-tion of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. J Pharmacol Exp Ther 2001; 296:235-42.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 235-242
-
-
Dunford, J.E.1
Thompson, K.2
Coxon, F.P.3
-
13
-
-
0034162528
-
Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: Long term follow-up of two randomized, placebo-controlled trials
-
Lipton A, Theriault RL, Hortobagyi GN, et al. Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebo-controlled trials. Cancer 2000; 88:1082-90.
-
(2000)
Cancer
, vol.88
, pp. 1082-1090
-
-
Lipton, A.1
Theriault, R.L.2
Hortobagyi, G.N.3
-
14
-
-
20644449488
-
Zoledronic acid significantly reduces skeletal com-plications compared with placebo in Japanese women with bone metastases from breast cancer: A randomized, placebo-controlled trial
-
Kohno N, Aogi K, Minami H, et al. Zoledronic acid significantly reduces skeletal com-plications compared with placebo in Japanese women with bone metastases from breast cancer: a randomized, placebo-controlled trial. J Clin Oncol 2005;23:3314-21.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3314-3321
-
-
Kohno, N.1
Aogi, K.2
Minami, H.3
-
15
-
-
17144447171
-
Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases
-
Body JJ, Diel IJ, Lichinitser MR, et al. Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases. Ann Oncol 2003; 14:1399-405.
-
(2003)
Ann Oncol
, vol.14
, pp. 1399-1405
-
-
Body, J.J.1
Diel, I.J.2
Lichinitser, M.R.3
-
16
-
-
36248938315
-
Antitumor effect of zoledronic acid in previously untreated patients with multiple myeloma
-
Avilés A, Nambo MJ, Neri N, et al. Antitumor effect of zoledronic acid in previously untreated patients with multiple myeloma. Med Oncol 2007; 24:227-30.
-
(2007)
Med Oncol
, vol.24
, pp. 227-230
-
-
Avilés, A.1
Nambo, M.J.2
Neri, N.3
-
17
-
-
85206959867
-
Effect of zoledronic acid (Zol) compared with pamidronate (Pam) on disease progression in breast cancer (BC) patients with bone metastases stratified by baseline characteristics
-
abstract 678
-
Hei Y, Lipton A, Shirina N, et al. Effect of zoledronic acid (Zol) compared with pamidronate (Pam) on disease progression in breast cancer (BC) patients with bone metastases stratified by baseline characteristics. J Clin Oncol 2006; 24(18 suppl.):47s (abstract 678).
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 SUPPL.
-
-
Hei, Y.1
Lipton, A.2
Shirina, N.3
-
18
-
-
43249128301
-
Zoledronic acid and survival in patients with meta-static bone disease from lung cancer and elevated markers of osteoclast activity
-
Hirsh V, Major PP, Lipton A, et al. Zoledronic acid and survival in patients with meta-static bone disease from lung cancer and elevated markers of osteoclast activity J Thorac Oncol 2008; 3:228-36.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 228-236
-
-
Hirsh, V.1
Major, P.P.2
Lipton, A.3
-
19
-
-
0041386301
-
Zoledronic acid delays the onset of skeletal-related events and progression of skeletal disease in patients with advanced renal cell carcinoma
-
Lipton A, Zheng M, Seaman J. Zoledronic acid delays the onset of skeletal-related events and progression of skeletal disease in patients with advanced renal cell carcinoma. Cancer 2003; 98:962-9.
-
(2003)
Cancer
, vol.98
, pp. 962-969
-
-
Lipton, A.1
Zheng, M.2
Seaman, J.3
-
20
-
-
22344455489
-
Randomized, open label, prospective study on the effect of zoledronic acid on the prevention of bone metastases in patients with recurrent solid tumors that did not present with bone metastases at baseline
-
Mystakidou K, Katsouda E, Parpa E, et al. Randomized, open label, prospective study on the effect of zoledronic acid on the prevention of bone metastases in patients with recurrent solid tumors that did not present with bone metastases at baseline. Med Oncol 2005; 22:195-201.
-
(2005)
Med Oncol
, vol.22
, pp. 195-201
-
-
Mystakidou, K.1
Katsouda, E.2
Parpa, E.3
-
21
-
-
68949184892
-
A controlled prospective randomized placebo-controlled trial of zoledronic acid in bony metastatic bladder cancer patients
-
abstract 5033
-
Zaghloul MS, Boutrus R, El-Hosieny H, et al. A controlled prospective randomized placebo-controlled trial of zoledronic acid in bony metastatic bladder cancer patients. J Clin Oncol 2008; 26(15 suppl):257s (abstract 5033).
-
(2008)
J Clin Oncol
, vol.26
, Issue.15 SUPPL.
-
-
Zaghloul, M.S.1
Boutrus, R.2
El-Hosieny, H.3
-
23
-
-
60549097419
-
Endocrine therapy plus zoledronic acid in premenopausal breast cancer
-
Gnant M, Mlineritsch B, Schippinger W, et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N Engl J Med 2009; 36 0:679-91.
-
(2009)
N Engl J Med
, vol.36
, Issue.0
, pp. 679-691
-
-
Gnant, M.1
Mlineritsch, B.2
Schippinger, W.3
-
24
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002; 2:584-93.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
25
-
-
0030931858
-
Bisphosphonates induce apoptosis in human myeloma cell lines: A novel anti-tumour activity
-
Shipman CM, Rogers MJ, Apperley JF, et al. Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity. Br J Haematol 1997; 98:665-72.
-
(1997)
Br J Haematol
, vol.98
, pp. 665-672
-
-
Shipman, C.M.1
Rogers, M.J.2
Apperley, J.F.3
-
26
-
-
0034107048
-
Bisphosphonates induce apoptosis in human breast cancer cell lines
-
Senaratne SG, Pirianov G, Mansi JL, et al. Bisphosphonates induce apoptosis in human breast cancer cell lines. Br J Cancer 2000; 82:1459-68.
-
(2000)
Br J Cancer
, vol.82
, pp. 1459-1468
-
-
Senaratne, S.G.1
Pirianov, G.2
Mansi, J.L.3
-
27
-
-
0033783227
-
Bisphosphonates induce breast cancer cell death in vitro
-
Fromigue O, Lagneaux L, Body JJ. Bisphosphonates induce breast cancer cell death in vitro. J Bone Miner Res 2000; 15:2211-21.
-
(2000)
J Bone Miner Res
, vol.15
, pp. 2211-2221
-
-
Fromigue, O.1
Lagneaux, L.2
Body, J.J.3
-
28
-
-
3242771333
-
Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenyl-ation
-
Coxon JP, Oades GM, Kirby RS, et al. Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenyl-ation. BJU Int 2004; 94:164-70.
-
(2004)
BJU Int
, vol.94
, pp. 164-170
-
-
Coxon, J.P.1
Oades, G.M.2
Kirby, R.S.3
-
29
-
-
0034214362
-
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
-
Boissier S, Ferreras M, Peyruchaud O, et al. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases. Cancer Res 2000; 60:2949-54.
-
(2000)
Cancer Res
, vol.60
, pp. 2949-2954
-
-
Boissier, S.1
Ferreras, M.2
Peyruchaud, O.3
-
30
-
-
0038792653
-
New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and-independent effects
-
Denoyelle C, Hong L, Vannier JP, et al. New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and-independent effects. Br J Cancer 2003; 88:1631-40.
-
(2003)
Br J Cancer
, vol.88
, pp. 1631-1640
-
-
Denoyelle, C.1
Hong, L.2
Vannier, J.P.3
-
31
-
-
0018645854
-
Effects of disodium dichloromethylene diphosphonate on Paget's disease of bone
-
Meunier PJ, Chapuy MC, Alexandre C, et al. Effects of disodium dichloromethylene diphosphonate on Paget's disease of bone. Lancet 1979; 2:489-92.
-
(1979)
Lancet
, vol.2
, pp. 489-492
-
-
Meunier, P.J.1
Chapuy, M.C.2
Alexandre, C.3
-
32
-
-
0037112368
-
Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats
-
Fournier P, Boissier S, Filleur S, et al. Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats. Cancer Res 2002; 62:6538-44.
-
(2002)
Cancer Res
, vol.62
, pp. 6538-6544
-
-
Fournier, P.1
Boissier, S.2
Filleur, S.3
-
33
-
-
0036721078
-
Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid
-
Wood J, Bonjean K, Ruetz S, et al. Novel antiangiogenic effects of the bisphosphonate compound zoledronic acid. J Pharmacol Exp Ther 2002; 302:1055-61.
-
(2002)
J Pharmacol Exp Ther
, vol.302
, pp. 1055-1061
-
-
Wood, J.1
Bonjean, K.2
Ruetz, S.3
-
34
-
-
0029101805
-
Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice
-
Sasaki A, Boyce BF, Story B, et al. Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice. Cancer Res 1995; 55:3551-7.
-
(1995)
Cancer Res
, vol.55
, pp. 3551-3557
-
-
Sasaki, A.1
Boyce, B.F.2
Story, B.3
-
35
-
-
0034980406
-
Hiraga T Preclinical studies with zoledronic acid and other bisphosphonates: Impact on the bone microenvironment
-
Mundy GR, Yoneda T, Hiraga T Preclinical studies with zoledronic acid and other bisphosphonates: impact on the bone microenvironment. Semin Oncol 2001; 28(suppl 6):35-44.
-
(2001)
Semin Oncol
, vol.28
, Issue.SUPPL. 6
, pp. 35-44
-
-
Mundy, G.R.1
Yoneda, T.2
-
36
-
-
0036777368
-
The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs
-
Michigami T, Hiraga T, Williams PJ, et al. The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs. Breast Cancer Res Treat 2002; 75:249-58.
-
(2002)
Breast Cancer Res Treat
, vol.75
, pp. 249-258
-
-
Michigami, T.1
Hiraga, T.2
Williams, P.J.3
-
37
-
-
3042729728
-
Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model
-
Hiraga T, Williams PJ, Ueda A, et al. Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model. Clin Cancer Res 2004; 10:4559-67.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4559-4567
-
-
Hiraga, T.1
Williams, P.J.2
Ueda, A.3
-
38
-
-
33847771427
-
Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis
-
Daubine F, Le Gall C, Gasser J, et al. Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis. J Natl Cancer Inst 2007; 99:322-30.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 322-330
-
-
Daubine, F.1
Le Gall, C.2
Gasser, J.3
-
39
-
-
27144522528
-
Additive/synergistic antitumoral effects on prostate cancer cells in vitro following treatment with a combination of docetaxel and zoledronic acid
-
Ullen A, Lennartsson L, Harmenberg U, et al. Additive/synergistic antitumoral effects on prostate cancer cells in vitro following treatment with a combination of docetaxel and zoledronic acid. Acta Oncol 2005; 44:644-50.
-
(2005)
Acta Oncol
, vol.44
, pp. 644-650
-
-
Ullen, A.1
Lennartsson, L.2
Harmenberg, U.3
-
40
-
-
38049155886
-
Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
-
Brunsvig PF, Andersen A, Aamdal S, et al. Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy. BMC Cancer 2007; 7:197.
-
(2007)
BMC Cancer
, vol.7
, pp. 197
-
-
Brunsvig, P.F.1
Andersen, A.2
Aamdal, S.3
-
41
-
-
29144521942
-
Zoledronic acid cooperates with a cyclooxy-genase-2 inhibitor and gefitinib in inhibiting breast and prostate cancer
-
Melisi D, Caputo R, Damiano V, et al. Zoledronic acid cooperates with a cyclooxy-genase-2 inhibitor and gefitinib in inhibiting breast and prostate cancer. Endocr Relat Cancer 2005; 12:1051-8.
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 1051-1058
-
-
Melisi, D.1
Caputo, R.2
Damiano, V.3
-
42
-
-
16544379650
-
Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/methotrexate/5-fluorouracil, epirubicin/cyclo-phosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid
-
Vogt U, Bielawski KP, Bosse U, et al. Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/methotrexate/5-fluorouracil, epirubicin/cyclo-phosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid. Oncol Rep 2004; 12:1109-14.
-
(2004)
Oncol Rep
, vol.12
, pp. 1109-1114
-
-
Vogt, U.1
Bielawski, K.P.2
Bosse, U.3
-
43
-
-
51049114468
-
Antitumor effects of doxorubicin fol-lowed by zoledronic acid in a mouse model of breast cancer
-
Ottewell PD, Monkkonen H, Jones M, et al. Antitumor effects of doxorubicin fol-lowed by zoledronic acid in a mouse model of breast cancer. J Natl Cancer Inst 2008; 100:1167-78.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1167-1178
-
-
Ottewell, P.D.1
Monkkonen, H.2
Jones, M.3
-
44
-
-
6844252283
-
Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group
-
Berenson JR, Lichtenstein A, Porter L, et al. Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group. J Clin Oncol 1998; 16:593-602.
-
(1998)
J Clin Oncol
, vol.16
, pp. 593-602
-
-
Berenson, J.R.1
Lichtenstein, A.2
Porter, L.3
-
45
-
-
0027169349
-
Rapid generation of antiplasma cell activity in the bone marrow of myeloma patients by CD3-activated T cells
-
Massaia M, Attisano C, Peola S, et al. Rapid generation of antiplasma cell activity in the bone marrow of myeloma patients by CD3-activated T cells. Blood 1993; 82:1787-97.
-
(1993)
Blood
, vol.82
, pp. 1787-1797
-
-
Massaia, M.1
Attisano, C.2
Peola, S.3
-
46
-
-
0034660687
-
Stimulation of gamma delta T cells by amino-bisphosphonates and induction of antiplasma cell activity in multiple myeloma
-
Kunzmann V, Bauer E, Feurle J, et al. Stimulation of gamma delta T cells by amino-bisphosphonates and induction of antiplasma cell activity in multiple myeloma. Blood 2000; 96:384-92.
-
(2000)
Blood
, vol.96
, pp. 384-392
-
-
Kunzmann, V.1
Bauer, E.2
Feurle, J.3
-
47
-
-
20444445149
-
Cytotoxic effects of gamma delta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy
-
Sato K, Kimura S, Segawa H, et al. Cytotoxic effects of gamma delta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy Int J Cancer 2005; 116:94-9.
-
(2005)
Int J Cancer
, vol.116
, pp. 94-99
-
-
Sato, K.1
Kimura, S.2
Segawa, H.3
-
48
-
-
59449106667
-
Intravesical administration of gamma delta T cells suc-cessfully prevents the growth of bladder cancer in the murine model
-
Yuasa T, Sato K, Ashihara E, et al. Intravesical administration of gamma delta T cells suc-cessfully prevents the growth of bladder cancer in the murine model. Cancer Immunol Immunother 2009; 58:493-502
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 493-502
-
-
Yuasa, T.1
Sato, K.2
Ashihara, E.3
-
49
-
-
34547962875
-
Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acid
-
Fiore F, Castella B, Nuschak B, et al. Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acid. Blood 2007; 110:921-7.
-
(2007)
Blood
, vol.110
, pp. 921-927
-
-
Fiore, F.1
Castella, B.2
Nuschak, B.3
-
50
-
-
0036093899
-
Pamidronate induces modifications of circulat-ing angiogenetic factors in cancer patients
-
Santini D, Vincenzi B, Avvisati G, et al. Pamidronate induces modifications of circulat-ing angiogenetic factors in cancer patients. Clin Cancer Res 2002; 8:1080-4.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1080-1084
-
-
Santini, D.1
Vincenzi, B.2
Avvisati, G.3
-
51
-
-
10744227993
-
Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients
-
Santini D, Vincenzi B, Dicuonzo G, et al. Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients. Clin Cancer Res 2003; 9:2893-7.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2893-2897
-
-
Santini, D.1
Vincenzi, B.2
Dicuonzo, G.3
-
52
-
-
54849441655
-
In vivo effects of zoledronic acid on peripheral gamma delta T lymphocytes in early breast cancer patients
-
Santini D, Martini F, Fratto ME, et al. In vivo effects of zoledronic acid on peripheral gamma delta T lymphocytes in early breast cancer patients. Cancer Immunol Immunother 2009; 58:31-8.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 31-38
-
-
Santini, D.1
Martini, F.2
Fratto, M.E.3
-
53
-
-
33846813974
-
Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: A pilot study
-
Kobayashi H, Tanaka Y, Yagi J, et al. Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study Cancer Immunol Immunother 2007; 56:469-76.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 469-476
-
-
Kobayashi, H.1
Tanaka, Y.2
Yagi, J.3
-
54
-
-
34247521438
-
Priming the "soil" for breast cancer metastasis: The premetastatic niche
-
Psaila B, Kaplan RN, Port ER, et al. Priming the "soil" for breast cancer metastasis: the premetastatic niche. Breast Dis 2006-2007; 26:65-74.
-
(2006)
Breast Dis
, vol.26
, pp. 65-74
-
-
Psaila, B.1
Kaplan, R.N.2
Port, E.R.3
-
55
-
-
43749115751
-
The bone marrow niche: Habitat to he-matopoietic and mesenchymal stem cells, and unwitting host to molecular parasites
-
Shiozawa Y, Havens AM, Pienta KJ, et al. The bone marrow niche: habitat to he-matopoietic and mesenchymal stem cells, and unwitting host to molecular parasites. Leukemia 2008; 22:941-50.
-
(2008)
Leukemia
, vol.22
, pp. 941-950
-
-
Shiozawa, Y.1
Havens, A.M.2
Pienta, K.J.3
-
56
-
-
34247541322
-
New insights into the pathogenesis of breast cancer metastasis
-
Tarin D. New insights into the pathogenesis of breast cancer metastasis. Breast Dis 2006-2007; 26:13-25.
-
(2006)
Breast Dis
, vol.26
, pp. 13-25
-
-
Tarin, D.1
-
57
-
-
50349096764
-
Disseminated tumor cells of breast cancer patients: A strong prognostic factor for distant and local relapse
-
Bidard FC, Vincent-Salomon A, Gomme S, et al. Disseminated tumor cells of breast cancer patients: a strong prognostic factor for distant and local relapse. Clin Cancer Res 2008; 14:3306-11.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3306-3311
-
-
Bidard, F.C.1
Vincent-Salomon, A.2
Gomme, S.3
-
58
-
-
23944466427
-
A pooled analysis of bone marrow micrometastasis in breast cancer
-
DOI 10.1056/NEJMoa050434
-
Braun S, Vogl FD, Naume B, et al. A pooled analysis of bone marrow micrometastasis in breast cancer. N Engl J Med 2005; 353:793-802. (Pubitemid 41215488)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.8
, pp. 793-802
-
-
Braun, S.1
Vogl, F.D.2
Naume, B.3
Janni, W.4
Osborne, M.P.5
Coombes, R.C.6
Schlimok, G.7
Diel, I.J.8
Gerber, B.9
Gebauer, G.10
Pierga, J.-Y.11
Marth, C.12
Oruzio, D.13
Wiedswang, G.14
Solomayer, E.-F.15
Kundt, G.16
Strobl, B.17
Fehm, T.18
Wong, G.Y.C.19
Bliss, J.20
Vincent-Salomon, A.21
Pantel, K.22
more..
-
59
-
-
77953455150
-
Effect of zoledronic acid on bone marrow micro-metastases in women undergoing neoadjuvant chemotherapy for breast cancer [poster]
-
May 30-June 3 Chicago, IL. Abstract 1021
-
Aft R, Naughton M, Ylagan L, et al. Effect of zoledronic acid on bone marrow micro-metastases in women undergoing neoadjuvant chemotherapy for breast cancer [poster]. Presented at: the 44th Annual Meeting of the American Society of Clinical Oncology; May 30-June 3, 2008; Chicago, IL. Abstract 1021.
-
(2008)
Presented At: The 44th Annual Meeting of the American Society of Clinical Oncology
-
-
Aft, R.1
Naughton, M.2
Ylagan, L.3
-
60
-
-
73549100990
-
Zoledronic acid as adjuvant therapy for women with early stage breast cancer and occult tumor cells in bone marrow [poster]
-
December 13-16 San Antonio, TX. Abstract 510
-
Lin A, Park J, Melisko M, et al. Zoledronic acid as adjuvant therapy for women with early stage breast cancer and occult tumor cells in bone marrow [poster]. Presented at: the 30th Annual San Antonio Breast Cancer Symposium; December 13-16, 2007; San Antonio, TX. Abstract 510.
-
(2007)
Presented At: The 30th Annual San Antonio Breast Cancer Symposium
-
-
Lin, A.1
Park, J.2
Melisko, M.3
-
61
-
-
66349135597
-
Effect of zoledronate on persisting isolated tumor cells in the bone marrow of patients without recurrence of early breast cancer [poster]
-
December 13-16 San Antonio, TX. Abstract 511
-
Rack BK, Jueckstock J, Genss E-M, et al. Effect of zoledronate on persisting isolated tumor cells in the bone marrow of patients without recurrence of early breast cancer [poster]. Presented at: the 30th Annual San Antonio Breast Cancer Symposium; December 13-16, 2007; San Antonio, TX. Abstract 511.
-
(2007)
Presented At: The 30th Annual San Antonio Breast Cancer Symposium
-
-
Rack, B.K.1
Jueckstock, J.2
Genss, E.-M.3
-
62
-
-
78649267109
-
Influence of zoledronic acid on disseminated tumor cells (DTC) in primary breast cancer patients [poster]
-
December 10-14 San Antonio, TX. Abstract 2048
-
Solomayer EF, Gebauer G, Hirnle P, et al. Influence of zoledronic acid on disseminated tumor cells (DTC) in primary breast cancer patients [poster]. Presented at: the 31st Annual San Antonio Breast Cancer Symposium; December 10-14, 2008; San Antonio, TX. Abstract 2048.
-
(2008)
Presented At: The 31st Annual San Antonio Breast Cancer Symposium
-
-
Solomayer, E.F.1
Gebauer, G.2
Hirnle, P.3
-
63
-
-
33744828376
-
Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer
-
Powles T, Paterson A, McCloskey E, et al. Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer. Breast Cancer Res 2006; 8:R13.
-
(2006)
Breast Cancer Res
, vol.8
-
-
Powles, T.1
Paterson, A.2
McCloskey, E.3
-
64
-
-
0032491037
-
Reduction in new metastases in breast cancer with adjuvant clodronate treatment
-
Diel IJ, Solomayer EF, Costa SD, et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med 1998; 339:357-63.
-
(1998)
N Engl J Med
, vol.339
, pp. 357-363
-
-
Diel, I.J.1
Solomayer, E.F.2
Costa, S.D.3
-
65
-
-
5444270251
-
Adjuvant clodronate treatment improves the overall survival of primary breast cancer patients with micrometastases to bone marrow-a longtime follow-up
-
abstract 529
-
Jaschke A, Bastert G, Solomayer EF, et al. Adjuvant clodronate treatment improves the overall survival of primary breast cancer patients with micrometastases to bone marrow-a longtime follow-up. J Clin Oncol 2004; 22(14 suppl):9 (abstract 529).
-
(2004)
J Clin Oncol
, vol.22
, Issue.14 SUPPL.
, pp. 9
-
-
Jaschke, A.1
Bastert, G.2
Solomayer, E.F.3
-
66
-
-
56749165071
-
Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow a long-term follow-up
-
Diel IJ, Jaschke A, Solomayer EF, et al. Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow a long-term follow-up. Ann Oncol 2008; 19:2007-11.
-
(2008)
Ann Oncol
, vol.19
, pp. 2007-2011
-
-
Diel, I.J.1
Jaschke, A.2
Solomayer, E.F.3
-
67
-
-
9444254706
-
Ten-year follow-up of a randomized con-trolled trial of adjuvant clodronate treatment in node-positive breast cancer patients
-
Saarto T, Vehmanen L, Virkkunen P, et al. Ten-year follow-up of a randomized con-trolled trial of adjuvant clodronate treatment in node-positive breast cancer patients. Acta Oncol 2004; 43:650-6.
-
(2004)
Acta Oncol
, vol.43
, pp. 650-656
-
-
Saarto, T.1
Vehmanen, L.2
Virkkunen, P.3
-
68
-
-
34250326616
-
Meta-analysis of clodronate and breast cancer survival
-
Ha TC, Li H. Meta-analysis of clodronate and breast cancer survival. Br J Cancer 2007; 96:1796-801.
-
(2007)
Br J Cancer
, vol.96
, pp. 1796-1801
-
-
Ha, T.C.1
Li, H.2
-
69
-
-
10544228130
-
Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group
-
Hortobagyi GN, Theriault RL, Porter L, et al. Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group. N Engl J Med 1996; 335:1785-91.
-
(1996)
N Engl J Med
, vol.335
, pp. 1785-1791
-
-
Hortobagyi, G.N.1
Theriault, R.L.2
Porter, L.3
-
70
-
-
33646873043
-
Benefit of taxanes as adjuvant chemotherapy for early breast cancer: Pooled analysis of 15,500 patients
-
Bria E, Nistico C, Cuppone F, et al. Benefit of taxanes as adjuvant chemotherapy for early breast cancer: pooled analysis of 15,500 patients. Cancer 2006; 106:2337-44.
-
(2006)
Cancer
, vol.106
, pp. 2337-2344
-
-
Bria, E.1
Nistico, C.2
Cuppone, F.3
-
71
-
-
77953376340
-
The effect of zoledronic acid on aroma-tase inhibitor (AI) associated bone loss (AIBL) in postmenopausal women (PMW) with early breast cancer (EBC) receiving adjuvant letrozole: 24 months (mos) integrated follow-up of the Z-FAST/ZO-FAST trials
-
abstract 185PD
-
Frassoldati A, Brufsky A, Bundred N, et al. The effect of zoledronic acid on aroma-tase inhibitor (AI) associated bone loss (AIBL) in postmenopausal women (PMW) with early breast cancer (EBC) receiving adjuvant letrozole: 24 months (mos) integrated follow-up of the Z-FAST/ZO-FAST trials. Ann Oncol 2008; 19(suppl 8):viii78 (abstract 185PD).
-
(2008)
Ann Oncol
, vol.19
, Issue.SUPPL. 8
-
-
Frassoldati, A.1
Brufsky, A.2
Bundred, N.3
-
72
-
-
67649804881
-
Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST Study 36-month follow-up results
-
Brufsky AM, Bosserman LD, Caradonna RR, et al. Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST Study 36-month follow-up results. Clin Breast Cancer 2009; 9:77-85.
-
(2009)
Clin Breast Cancer
, vol.9
, pp. 77-85
-
-
Brufsky, A.M.1
Bosserman, L.D.2
Caradonna, R.R.3
-
73
-
-
69249218221
-
The addition of zoledronic acid to neoadjuvant chemotherapy may influence pathological response-exploratory evidence for direct anti-tumor activity in breast cancer [poster]
-
December 10-14 San Antonio, TX Abstract 5101
-
Winter MC, Thorpe HC, Burkinshaw R, et al. The addition of zoledronic acid to neoadjuvant chemotherapy may influence pathological response-exploratory evidence for direct anti-tumor activity in breast cancer [poster]. Presented at the 31st Annual San Antonio Breast Cancer Symposium; December 10-14, 2008; San Antonio, TX Abstract 5101.
-
(2008)
Presented at the 31st Annual San Antonio Breast Cancer Symposium
-
-
Winter, M.C.1
Thorpe, H.C.2
Burkinshaw, R.3
-
74
-
-
85206960124
-
ICE Study: Ibandronate with or without capecitabine in elderly patients with early breast cancer
-
abstract 0155
-
Reimer T, Nitz U, Potenberg J, et al. ICE Study: Ibandronate with or without capecitabine in elderly patients with early breast cancer. Breast 2009; 18(suppl 1):S58 (abstract 0155).
-
(2009)
Breast
, vol.18
, Issue.SUPPL. 1
-
-
Reimer, T.1
Nitz, U.2
Potenberg, J.3
-
76
-
-
40149083563
-
Guidance on the use of bisphosphonates in solid tumours: Recommendations of an international expert panel
-
Aapro M, Abrahamsson PA, Body JJ, et al. Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel. Ann Oncol 2008; 19:420-32.
-
(2008)
Ann Oncol
, vol.19
, pp. 420-432
-
-
Aapro, M.1
Abrahamsson, P.A.2
Body, J.J.3
-
77
-
-
78650923720
-
Zoledronic acid in the prevention of aromatase inhibitor-associated bone loss in postmenopausal women receiving letrozole as adjuvant therapy for early breast cancer (E-ZO-FAST Trial) [poster]
-
Abstract 2.044 Barcelona Spain September 23-27
-
Llombart A. Zoledronic acid in the prevention of aromatase inhibitor-associated bone loss in postmenopausal women receiving letrozole as adjuvant therapy for early breast cancer (E-ZO-FAST Trial) [poster]. Presented at: the European Cancer Conference 14; Barcelona, Spain; September 23-27, 2007. Abstract 2.044.
-
(2007)
Presented At: The European Cancer Conference 14
-
-
Llombart, A.1
-
79
-
-
78649675975
-
A double-blind randomized study of denosumab versus zoledronic acid for the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma [oral presentation]
-
Abstract 20LBA Berlin Germany; September 20-24
-
Henry D, von Moos R, Vadhan-Raj S, et al. A double-blind, randomized study of denosumab versus zoledronic acid for the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma [oral presentation]. Presented at: the European Cancer Conference 15-34th European Society for Medical Oncology Multidisciplinary Congress; Berlin, Germany; September 20-24, 2009. Abstract 20LBA
-
(2009)
Presented At: The European Cancer Conference 15-34th European Society for Medical Oncology Multidisciplinary Congress
-
-
Henry, D.1
Von Moos, R.2
Vadhan-Raj, S.3
-
80
-
-
44449153039
-
Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates
-
Hoff AO, Toth BB, Altundag K, et al. Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates. J Bone Miner Res 2008; 23:826-36.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 826-836
-
-
Hoff, A.O.1
Toth, B.B.2
Altundag, K.3
-
81
-
-
50649114676
-
Osteonecrosis of the maxilla and mandible in patients with advanced cancer treated with bisphosphonate therapy
-
Estilo CL, Van Poznak CH, Wiliams T, et al. Osteonecrosis of the maxilla and mandible in patients with advanced cancer treated with bisphosphonate therapy Oncologist 2008; 13:911-20.
-
(2008)
Oncologist
, vol.13
, pp. 911-920
-
-
Estilo, C.L.1
Van Poznak, C.H.2
Wiliams, T.3
-
82
-
-
58949093771
-
Decreased occurrence of osteonecro-sis of the jaw after implementation of dental preventive measures in solid tumour patients with bone metastases treated with bisphosphonates
-
The experience of the National Cancer Institute of Milan
-
Ripamonti CI, Maniezzo M, Campa T, et al. Decreased occurrence of osteonecro-sis of the jaw after implementation of dental preventive measures in solid tumour patients with bone metastases treated with bisphosphonates. The experience of the National Cancer Institute of Milan. Ann Oncol 2009; 20:137-45.
-
(2009)
Ann Oncol
, vol.20
, pp. 137-145
-
-
Ripamonti, C.I.1
Maniezzo, M.2
Campa, T.3
-
83
-
-
34848841461
-
Bisphosphonate-associated osteonecrosis of the jaw: Report of a task force of the American Society for Bone and Mineral Research
-
Khosla S, Burr D, Cauley J, et al. Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2007; 22:1479-91.
-
(2007)
J Bone Miner Res
, vol.22
, pp. 1479-1491
-
-
Khosla, S.1
Burr, D.2
Cauley, J.3
-
84
-
-
34147095972
-
Critical review: Updated recommenda-tions for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients-May 2006
-
Weitzman R, Sauter N, Eriksen EF, et al. Critical review: updated recommenda-tions for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in cancer patients-May 2006. Crit Rev Oncol Hematol 2007; 62:148-52.
-
(2007)
Crit Rev Oncol Hematol
, vol.62
, pp. 148-152
-
-
Weitzman, R.1
Sauter, N.2
Eriksen, E.F.3
-
85
-
-
45749089797
-
Integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole
-
Brufsky A, Bundred N, Coleman R, et al. Integrated analysis of zoledronic acid for prevention of aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole. Oncologist 2008; 13:503-14.
-
(2008)
Oncologist
, vol.13
, pp. 503-514
-
-
Brufsky, A.1
Bundred, N.2
Coleman, R.3
-
86
-
-
54449084015
-
Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer
-
Ellis GK, Bone HG, Chlebowski R, et al. Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer. J Clin Oncol 2008; 26:4875-82.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4875-4882
-
-
Ellis, G.K.1
Bone, H.G.2
Chlebowski, R.3
-
87
-
-
77950616066
-
SRC kinase inhibition: Targeting bone metastases and tumor growth in prostate and breast cancer
-
Saad F, Lipton A. SRC kinase inhibition: targeting bone metastases and tumor growth in prostate and breast cancer. Cancer Treat Rev 2010; 36:177-84.
-
(2010)
Cancer Treat Rev
, vol.36
, pp. 177-184
-
-
Saad, F.1
Lipton, A.2
-
88
-
-
67649846431
-
Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells
-
Pichot CS, Hartig SM, Xia L, et al. Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells. Br J Cancer 2009; 101:38-47.
-
(2009)
Br J Cancer
, vol.101
, pp. 38-47
-
-
Pichot, C.S.1
Hartig, S.M.2
Xia, L.3
-
89
-
-
59249108004
-
Dasatinib in patients with hormone-refractory progressive prostate cancer: A phase II study
-
abstract 5156
-
Yu EY, Wilding G, Posadas E, et al. Dasatinib in patients with hormone-refractory progressive prostate cancer: a phase II study. J Clin Oncol 2008; 26(15 suppl):288s (abstract 5156).
-
(2008)
J Clin Oncol
, vol.26
, Issue.15 SUPPL.
-
-
Yu, E.Y.1
Wilding, G.2
Posadas, E.3
-
90
-
-
77953433829
-
Effects of the Src kinase inhibitor saraca-tinib (AZD0530) on bone turnover in healthy men: A randomized, double-blind, placebo-controlled, multiple ascending dose phase i trial
-
Hannon RA, Clack G, Rimmer M, et al. Effects of the Src kinase inhibitor saraca-tinib (AZD0530) on bone turnover in healthy men: a randomized, double-blind, placebo-controlled, multiple ascending dose phase I trial. J Bone Miner Res 2010; 25:463-71.
-
(2010)
J Bone Miner Res
, vol.25
, pp. 463-471
-
-
Hannon, R.A.1
Clack, G.2
Rimmer, M.3
|