SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML

Oncogene

Volumn 29, Issue 40, 2010, Pages 5511-5522

  Wimmer, P ^a   Schreiner, S ^a   Everett, R D ^b   Sirma, H ^c   Groitl, P ^a   Dobner, T ^a  

^a LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^b INSTITUTE OF VIROLOGY   (United Kingdom)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

HAdV5 E1B 55K; PML isoforms; SUMO

Indexed keywords

E1B PROTEIN; ONCOPROTEIN; ONCOPROTEIN 55K; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN P53; SUMO 1 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; ISOPROTEIN; NUCLEAR PROTEIN; PML PROTEIN, HUMAN; PROTEIN BINDING; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ADENOVIRUS 5; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL TRANSFORMATION; CONTROLLED STUDY; DNA REPAIR; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; SUMOYLATION; VIRUS INFECTION; ANIMAL; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; IMMUNOBLOTTING; IMMUNOPRECIPITATION; METABOLISM; PHYSIOLOGY; RAT; VIRUS CELL TRANSFORMATION;

ADENOVIRUS E1B PROTEINS; ANIMALS; CELL LINE; CELL TRANSFORMATION, VIRAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PROTEIN BINDING; PROTEIN ISOFORMS; RATS; SUMO-1 PROTEIN; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

ADENOVIRIDAE; HUMAN ADENOVIRUS; MAMMALIA;

EID: 77957808656     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.284     Document Type: Article

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