메뉴 건너뛰기




Volumn 97, Issue 1, 2010, Pages 92-100

Effects of acute low-dose combined treatment with rimonabant and sibutramine on appetite and weight gain in rats

Author keywords

Behavioural satiety sequence; Feeding behaviour; Food intake; Low doses; Monotherapy; Polytherapy; Rats; Rimonabant; Sibutramine

Indexed keywords

NALOXONE; RIMONABANT; SIBUTRAMINE;

EID: 77957752999     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2009.12.010     Document Type: Article
Times cited : (7)

References (92)
  • 3
    • 0025924980 scopus 로고
    • A peripheral 5-HT1D-like receptor involved in serotonergic induced hindlimb scratching in rats
    • Berendsen H.H.G., Broekkamp C.L.E. A peripheral 5-HT1D-like receptor involved in serotonergic induced hindlimb scratching in rats. Eur J Pharmacol 1991, 194:201-208.
    • (1991) Eur J Pharmacol , vol.194 , pp. 201-208
    • Berendsen, H.H.G.1    Broekkamp, C.L.E.2
  • 4
    • 0025072947 scopus 로고
    • Possible involvement of 5HT1D receptors in drug-induced hindlimb scratching in rats
    • Berendsen H.H.G., Broekkamp C.L.E., van Delft A.M.L. Possible involvement of 5HT1D receptors in drug-induced hindlimb scratching in rats. European Eur J Pharmacol 1990, 183:1924-2925.
    • (1990) European Eur J Pharmacol , vol.183 , pp. 1924-2925
    • Berendsen, H.H.G.1    Broekkamp, C.L.E.2    van Delft, A.M.L.3
  • 5
    • 70649087160 scopus 로고    scopus 로고
    • Synergy between amylin and cholecystokinin for inhibition of food intake in mice
    • Bhavsar S., Watkins J., Young A. Synergy between amylin and cholecystokinin for inhibition of food intake in mice. Physiol Behav 2004, 81:781-793.
    • (2004) Physiol Behav , vol.81 , pp. 781-793
    • Bhavsar, S.1    Watkins, J.2    Young, A.3
  • 6
    • 0031779626 scopus 로고    scopus 로고
    • Serotonin and appetite regulation: implications for the treatment of obesity
    • Blundell J.E., Halford J.C.G. Serotonin and appetite regulation: implications for the treatment of obesity. CNS Drugs 1998, 9:473-495.
    • (1998) CNS Drugs , vol.9 , pp. 473-495
    • Blundell, J.E.1    Halford, J.C.G.2
  • 7
    • 33846014230 scopus 로고    scopus 로고
    • 1A receptors are involved in the anxiolytic effect of Δ-9 tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats
    • 1A receptors are involved in the anxiolytic effect of Δ-9 tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats. Eur J Pharmacol 2007, 555:156-163.
    • (2007) Eur J Pharmacol , vol.555 , pp. 156-163
    • Braida, D.1    Limonta, V.2    Malabarba, L.3    Zani, A.4    Sala, M.5
  • 8
    • 34249821944 scopus 로고    scopus 로고
    • Pharmacological treatment of the overweight patient
    • Bray G.A., Greenway F.L. Pharmacological treatment of the overweight patient. Pharmacol Rev 2007, 59:151-184.
    • (2007) Pharmacol Rev , vol.59 , pp. 151-184
    • Bray, G.A.1    Greenway, F.L.2
  • 9
    • 0037388354 scopus 로고    scopus 로고
    • Sibutramine decreases body weight gain and increases energy expenditure in obese Zucker rats without changes in NPY and orexins
    • Casado A., Rodriguez V.M., Portillo M.P., Macarulla M.T., Abecia L.C., Echevarria E., et al. Sibutramine decreases body weight gain and increases energy expenditure in obese Zucker rats without changes in NPY and orexins. Nutr Neurosci 2003, 6:103-111.
    • (2003) Nutr Neurosci , vol.6 , pp. 103-111
    • Casado, A.1    Rodriguez, V.M.2    Portillo, M.P.3    Macarulla, M.T.4    Abecia, L.C.5    Echevarria, E.6
  • 10
    • 0035338157 scopus 로고    scopus 로고
    • Pharmacotherapy of obesity: targets and perspectives
    • Chiesi M., Huppertz C., Hofbauer K.G. Pharmacotherapy of obesity: targets and perspectives. Trends Pharmacol Sci 2001, 22:247-254.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 247-254
    • Chiesi, M.1    Huppertz, C.2    Hofbauer, K.G.3
  • 11
    • 0035064737 scopus 로고    scopus 로고
    • Anti-obesity drugs: a critical review of current therapies and future opportunities
    • Clapham J.C., Arch J.R.S., Tadayyon M. Anti-obesity drugs: a critical review of current therapies and future opportunities. Pharmac Ther 2001, 89:81-121.
    • (2001) Pharmac Ther , vol.89 , pp. 81-121
    • Clapham, J.C.1    Arch, J.R.S.2    Tadayyon, M.3
  • 12
    • 0035144003 scopus 로고    scopus 로고
    • Drug treatment of obesity: from past failures to future successes?
    • Collins P., Williams G. Drug treatment of obesity: from past failures to future successes?. Br J Clin Pharmac 2001, 51:13-25.
    • (2001) Br J Clin Pharmac , vol.51 , pp. 13-25
    • Collins, P.1    Williams, G.2
  • 14
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • Cota D., Marsicano G., Tschop M., Grubler Y., Flachskamm C., Schubert M., et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 2003, 112:423-431.
    • (2003) J Clin Invest , vol.112 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschop, M.3    Grubler, Y.4    Flachskamm, C.5    Schubert, M.6
  • 15
    • 0033791204 scopus 로고    scopus 로고
    • Involvement of other neurotransmitters in behaviors induced by the cannabinoid CB1 receptor antagonist SR 141716A in naïve mice
    • Darmani N.A., Pandya D.K. Involvement of other neurotransmitters in behaviors induced by the cannabinoid CB1 receptor antagonist SR 141716A in naïve mice. J Neural Transm 2000, 107:931-945.
    • (2000) J Neural Transm , vol.107 , pp. 931-945
    • Darmani, N.A.1    Pandya, D.K.2
  • 16
    • 55849117700 scopus 로고    scopus 로고
    • CB1 receptor antagonism: biological basis for metabolic effects
    • DiMarzo V. CB1 receptor antagonism: biological basis for metabolic effects. Drug Discovery Today 2008, 13:1026-1041.
    • (2008) Drug Discovery Today , vol.13 , pp. 1026-1041
    • DiMarzo, V.1
  • 17
    • 0026477828 scopus 로고
    • Peripheral 5-carboxamidotryptamine induces hindlimb scratching by stimulating 5-HT1A receptors in rats
    • Eison A.S., Wright R.N., Freeman R. Peripheral 5-carboxamidotryptamine induces hindlimb scratching by stimulating 5-HT1A receptors in rats. Life Sci 1992, 51:95-99.
    • (1992) Life Sci , vol.51 , pp. 95-99
    • Eison, A.S.1    Wright, R.N.2    Freeman, R.3
  • 18
    • 0018610106 scopus 로고
    • Pruritis in polycythemia vera: treatment with aspirin and possibility of platelet involvement
    • Fjellner B., Hägermark Ö. Pruritis in polycythemia vera: treatment with aspirin and possibility of platelet involvement. Acta Derm Venereol 1979, 59:505-512.
    • (1979) Acta Derm Venereol , vol.59 , pp. 505-512
    • Fjellner, B.1    Hägermark, Ö.2
  • 20
    • 58149301316 scopus 로고    scopus 로고
    • Pharmacological targeting of the serotonergic system for the treatment of obesity
    • Garfield A.S., Heisler L.K. Pharmacological targeting of the serotonergic system for the treatment of obesity. J Physiol 2009, 587:49-60.
    • (2009) J Physiol , vol.587 , pp. 49-60
    • Garfield, A.S.1    Heisler, L.K.2
  • 21
    • 33744512931 scopus 로고    scopus 로고
    • Locomotion is the major determinant of sibutramine-induced increase in energy expenditure
    • Golozoubova V., Strauss F., Malmlöf K. Locomotion is the major determinant of sibutramine-induced increase in energy expenditure. Pharmacol Biochem Behav 2006, 83:517-527.
    • (2006) Pharmacol Biochem Behav , vol.83 , pp. 517-527
    • Golozoubova, V.1    Strauss, F.2    Malmlöf, K.3
  • 23
    • 0032793450 scopus 로고    scopus 로고
    • Studies on the role of serotonin receptor subtypes in the effect of sibutramine in various feeding paradigms in rats
    • Grignaschi G., Fanelli E., Scagnol I., Samanin R. Studies on the role of serotonin receptor subtypes in the effect of sibutramine in various feeding paradigms in rats. Brit J Pharmacol 1999, 127:1190-1194.
    • (1999) Brit J Pharmacol , vol.127 , pp. 1190-1194
    • Grignaschi, G.1    Fanelli, E.2    Scagnol, I.3    Samanin, R.4
  • 25
    • 0001612783 scopus 로고
    • Effects in the rat of sibutramine on food intake and the behavioural satiety sequence
    • Halford J.C.G., Heal D.J., Blundell J.E. Effects in the rat of sibutramine on food intake and the behavioural satiety sequence. Brit J Pharmacol 1995, 114:387P.
    • (1995) Brit J Pharmacol , vol.114
    • Halford, J.C.G.1    Heal, D.J.2    Blundell, J.E.3
  • 26
    • 0032189856 scopus 로고    scopus 로고
    • Behavioral satiety sequence (BSS) for the diagnosis of drug action on food intake
    • Halford J.C.G., Wanninayake S.C.D., Blundell J.E. Behavioral satiety sequence (BSS) for the diagnosis of drug action on food intake. Pharmacol Biochem Behav 1998, 61:159-168.
    • (1998) Pharmacol Biochem Behav , vol.61 , pp. 159-168
    • Halford, J.C.G.1    Wanninayake, S.C.D.2    Blundell, J.E.3
  • 27
    • 34247860697 scopus 로고    scopus 로고
    • Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice
    • Haring M., Marsicano G., Lutz B. Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice. Neuroscience 2007, 146:1212-1219.
    • (2007) Neuroscience , vol.146 , pp. 1212-1219
    • Haring, M.1    Marsicano, G.2    Lutz, B.3
  • 28
    • 0037074929 scopus 로고    scopus 로고
    • Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain
    • Hermann H., Marsicano G., Lutz B. Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain. Neuroscience 2002, 109:451-460.
    • (2002) Neuroscience , vol.109 , pp. 451-460
    • Hermann, H.1    Marsicano, G.2    Lutz, B.3
  • 29
    • 0036125176 scopus 로고    scopus 로고
    • Serotonin 2C receptor agonists and the behavioural satiety sequence in mice
    • Hewitt K.N., Lee M.D., Dourish C.T., Clifton P.T. Serotonin 2C receptor agonists and the behavioural satiety sequence in mice. Pharmacol Biochem Behav 2002, 71:691-700.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 691-700
    • Hewitt, K.N.1    Lee, M.D.2    Dourish, C.T.3    Clifton, P.T.4
  • 30
    • 26044433145 scopus 로고    scopus 로고
    • Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?
    • Hill M.N., Gorzalka B.B. Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?. Behav Pharmacol 2005, 16:333-352.
    • (2005) Behav Pharmacol , vol.16 , pp. 333-352
    • Hill, M.N.1    Gorzalka, B.B.2
  • 31
    • 0038094446 scopus 로고    scopus 로고
    • Effects of systematic variation in presatiation and fasting on the behavioural satiety sequence in male rats
    • Ishii Y., Blundell J.E., Halford J.C.G., Rodgers R.J. Effects of systematic variation in presatiation and fasting on the behavioural satiety sequence in male rats. Physiol Behav 2003, 79:227-238.
    • (2003) Physiol Behav , vol.79 , pp. 227-238
    • Ishii, Y.1    Blundell, J.E.2    Halford, J.C.G.3    Rodgers, R.J.4
  • 32
    • 0030860731 scopus 로고    scopus 로고
    • Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat
    • Jackson H.C., Needham A.M., Hutchins L.J., Mazurkiewicz S.E., Heal D.J. Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat. Brit J Pharmacol 1997, 121:1758-1762.
    • (1997) Brit J Pharmacol , vol.121 , pp. 1758-1762
    • Jackson, H.C.1    Needham, A.M.2    Hutchins, L.J.3    Mazurkiewicz, S.E.4    Heal, D.J.5
  • 34
    • 33751363581 scopus 로고    scopus 로고
    • Effects of CB1R agonist WIN-55, 212-2 and the CB1R antagonists SR-141716 and AM-1387: open-field examination in rats
    • Jarbe T.U.C., Ross T., DiPatrizion N.V., Pandarinathan L., Makriyannis A. Effects of CB1R agonist WIN-55, 212-2 and the CB1R antagonists SR-141716 and AM-1387: open-field examination in rats. Pharmacol Biochem Behav 2006, 85:243-252.
    • (2006) Pharmacol Biochem Behav , vol.85 , pp. 243-252
    • Jarbe, T.U.C.1    Ross, T.2    DiPatrizion, N.V.3    Pandarinathan, L.4    Makriyannis, A.5
  • 35
    • 13844321589 scopus 로고    scopus 로고
    • Efficacy of sibutramine, orlistat and combination therapy on short-term weight management in obese patients
    • Kaya A., Aydin N., Topsever O., Filiz M., Ozturk A., Dagar A., et al. Efficacy of sibutramine, orlistat and combination therapy on short-term weight management in obese patients. Biomed Pharmacother 2004, 58:582-587.
    • (2004) Biomed Pharmacother , vol.58 , pp. 582-587
    • Kaya, A.1    Aydin, N.2    Topsever, O.3    Filiz, M.4    Ozturk, A.5    Dagar, A.6
  • 36
    • 33748704061 scopus 로고    scopus 로고
    • Cannabinoid-serotonin interactions in alcohol-preferring vs. alcohol-avoiding mice
    • Kelaï S., Hanoun N., Aufrère G., Beaugé F., Hamon M., Lanfumey L. Cannabinoid-serotonin interactions in alcohol-preferring vs. alcohol-avoiding mice. J Neurochem 2006, 99:308-320.
    • (2006) J Neurochem , vol.99 , pp. 308-320
    • Kelaï, S.1    Hanoun, N.2    Aufrère, G.3    Beaugé, F.4    Hamon, M.5    Lanfumey, L.6
  • 38
    • 0000022561 scopus 로고    scopus 로고
    • Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor
    • Kimura T., Ohta T., Watanabe K., Yoshimura H., Yamamoto I. Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. Biol Pharm Bull 1998, 21:224-226.
    • (1998) Biol Pharm Bull , vol.21 , pp. 224-226
    • Kimura, T.1    Ohta, T.2    Watanabe, K.3    Yoshimura, H.4    Yamamoto, I.5
  • 39
    • 67651065803 scopus 로고    scopus 로고
    • Cannabinoids and appetite: food craving and food pleasure
    • Kirkham T.C. Cannabinoids and appetite: food craving and food pleasure. Int Rev Psychiat 2009, 21:163-171.
    • (2009) Int Rev Psychiat , vol.21 , pp. 163-171
    • Kirkham, T.C.1
  • 40
    • 0035142565 scopus 로고    scopus 로고
    • Synergistic effects of opioid and cannabinoid antagonists on food intake
    • Kirkham T.C., Williams C.M. Synergistic effects of opioid and cannabinoid antagonists on food intake. Psychopharmacology 2001, 153:267-270.
    • (2001) Psychopharmacology , vol.153 , pp. 267-270
    • Kirkham, T.C.1    Williams, C.M.2
  • 41
    • 2942655401 scopus 로고    scopus 로고
    • Pharmacological approaches to weight reduction: therapeutic targets
    • Korner J., Aronne L.J. Pharmacological approaches to weight reduction: therapeutic targets. J Clin Endocr Metab 2004, 89:2616-2621.
    • (2004) J Clin Endocr Metab , vol.89 , pp. 2616-2621
    • Korner, J.1    Aronne, L.J.2
  • 42
    • 55549087935 scopus 로고    scopus 로고
    • Intracisternal, but not intrathecal, injection of naloxone inhibits cutaneous itch-related response in mice
    • Kuraishi Y., Yageta Y., Konno M., Andoh T., Yamaguchi-Miyamoto T., Nojima H. Intracisternal, but not intrathecal, injection of naloxone inhibits cutaneous itch-related response in mice. Biol Pharmaceut Bull 2008, 31:2143-2145.
    • (2008) Biol Pharmaceut Bull , vol.31 , pp. 2143-2145
    • Kuraishi, Y.1    Yageta, Y.2    Konno, M.3    Andoh, T.4    Yamaguchi-Miyamoto, T.5    Nojima, H.6
  • 43
    • 37349082417 scopus 로고    scopus 로고
    • 1 receptor is expressed on serotonergic and dopaminergic neurons
    • 1 receptor is expressed on serotonergic and dopaminergic neurons. Eur J Pharmacol 2008, 578:137-141.
    • (2008) Eur J Pharmacol , vol.578 , pp. 137-141
    • Lau, T.1    Schloss, P.2
  • 44
    • 0037066583 scopus 로고    scopus 로고
    • The discovery and status of sibutramine as an anti-obesity drug
    • Luque C.A., Rey J.A. The discovery and status of sibutramine as an anti-obesity drug. Eur J Pharmacol 2002, 440:119-128.
    • (2002) Eur J Pharmacol , vol.440 , pp. 119-128
    • Luque, C.A.1    Rey, J.A.2
  • 45
    • 0031595233 scopus 로고    scopus 로고
    • 9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat
    • 9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat. Brit J Pharmacol 1998, 124:1419-1424.
    • (1998) Brit J Pharmacol , vol.124 , pp. 1419-1424
    • Malone, D.T.1    Taylor, D.A.2
  • 46
    • 0034864983 scopus 로고    scopus 로고
    • 9-tetrahydrocannabinol-induced hypothermia in the rat
    • 9-tetrahydrocannabinol-induced hypothermia in the rat. Pharmacol Biochem Behav 2001, 69:595-601.
    • (2001) Pharmacol Biochem Behav , vol.69 , pp. 595-601
    • Malone, D.T.1    Taylor, D.A.2
  • 47
    • 1242339741 scopus 로고    scopus 로고
    • Involvement of 5-HT1A receptors in behavioural effects of the cannabinoid receptor agonist CP 55, 940 in male rats
    • Marco E.M., Pérez-Alvarez L., Borcel E., Rubio M., Guaza C., Ambrosio E., et al. Involvement of 5-HT1A receptors in behavioural effects of the cannabinoid receptor agonist CP 55, 940 in male rats. Behav Pharmacol 2004, 15:21-27.
    • (2004) Behav Pharmacol , vol.15 , pp. 21-27
    • Marco, E.M.1    Pérez-Alvarez, L.2    Borcel, E.3    Rubio, M.4    Guaza, C.5    Ambrosio, E.6
  • 49
    • 0032434821 scopus 로고    scopus 로고
    • Sibutramine. A review of its contribution to the management of obesity
    • McNeely W., Goa K.L. Sibutramine. A review of its contribution to the management of obesity. Drugs 1998, 56:1093-1124.
    • (1998) Drugs , vol.56 , pp. 1093-1124
    • McNeely, W.1    Goa, K.L.2
  • 52
    • 28744440285 scopus 로고    scopus 로고
    • Ethanol desensitizes cannabinoid CB1 receptors modulating monoamine synthesis in the rat brain in vivo
    • Moranta D., Esteban S., Garcia-Sevilla J.A. Ethanol desensitizes cannabinoid CB1 receptors modulating monoamine synthesis in the rat brain in vivo. Neurosci Letts 2006, 392:58-61.
    • (2006) Neurosci Letts , vol.392 , pp. 58-61
    • Moranta, D.1    Esteban, S.2    Garcia-Sevilla, J.A.3
  • 54
    • 0003968789 scopus 로고    scopus 로고
    • Auditor General, HMSO, Norwich, UK National Audit Office, National Audit Office
    • National Audit Office Tackling obesity in England 2001, Auditor General, HMSO, Norwich, UK National Audit Office.
    • (2001) Tackling obesity in England
  • 56
    • 77957752763 scopus 로고    scopus 로고
    • NIH Obesity Research Task Force
    • NIH Obesity Research Task Force 2004. http://www.obesityresearch.nih.gov.
    • (2004)
  • 57
    • 0034289861 scopus 로고    scopus 로고
    • An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action
    • Nisoli E., Carruba M.O. An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action. Obesity Revs 2000, 1:127-139.
    • (2000) Obesity Revs , vol.1 , pp. 127-139
    • Nisoli, E.1    Carruba, M.O.2
  • 58
    • 41649090426 scopus 로고    scopus 로고
    • Effect of rimonabant on progression of athersclerosis in patients with abdominal obesity and coronary heart disease: the STRADIVARIUS randomised controlled trial
    • Nissen S.E., Nicholls S.J., Wolski K., Rodes-Cabau J., Cannon C.P., Deanfield J.E., et al. Effect of rimonabant on progression of athersclerosis in patients with abdominal obesity and coronary heart disease: the STRADIVARIUS randomised controlled trial. JAMA 2008, 299:1547-1560.
    • (2008) JAMA , vol.299 , pp. 1547-1560
    • Nissen, S.E.1    Nicholls, S.J.2    Wolski, K.3    Rodes-Cabau, J.4    Cannon, C.P.5    Deanfield, J.E.6
  • 59
    • 0346250180 scopus 로고    scopus 로고
    • Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized control trials
    • Padwal R.S., Li S.K., Lau D.C.W. Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized control trials. Int J Obesity 2003, 27:1437-1446.
    • (2003) Int J Obesity , vol.27 , pp. 1437-1446
    • Padwal, R.S.1    Li, S.K.2    Lau, D.C.W.3
  • 60
    • 33845874637 scopus 로고    scopus 로고
    • Drug treatments for obesity: orlistat, sibutramine and rimonabant
    • Padwal R.S., Majumdar S.R. Drug treatments for obesity: orlistat, sibutramine and rimonabant. Lancet 2007, 369:71-77.
    • (2007) Lancet , vol.369 , pp. 71-77
    • Padwal, R.S.1    Majumdar, S.R.2
  • 61
    • 0027437262 scopus 로고
    • Medical hazards of obesity
    • Pi-Sunyer F.X. Medical hazards of obesity. Ann Intern Med 1993, 119:655-660.
    • (1993) Ann Intern Med , vol.119 , pp. 655-660
    • Pi-Sunyer, F.X.1
  • 63
    • 12444327152 scopus 로고    scopus 로고
    • Prevalence of obesity in Great Britain
    • Rennie K.L., Jebb S.A. Prevalence of obesity in Great Britain. Obesity Revs 2005, 6:11-12.
    • (2005) Obesity Revs , vol.6 , pp. 11-12
    • Rennie, K.L.1    Jebb, S.A.2
  • 64
    • 0035055943 scopus 로고    scopus 로고
    • SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats. Eur J Neurosci
    • Rodgers RJ, Halford JCG, Nunes de Souza RL, Canto de Souza AL, Piper DC, Arch JRS, et al. SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats. Eur J Neurosci 2001;13:1444-52.
    • (2001) , vol.13 , pp. 1444-52
    • Rodgers, R.J.1    Halford, J.C.G.2    Nunes de Souza, R.L.3    Canto de Souza, A.L.4    Piper, D.C.5    Arch, J.R.S.6
  • 66
    • 0033047023 scopus 로고    scopus 로고
    • Anorectic efficacy of the fenfluramine/phenteramine combination in rats: additivity or synergy
    • Roth J.D., Rowland N.E. Anorectic efficacy of the fenfluramine/phenteramine combination in rats: additivity or synergy. Eur J Pharmacol 1999, 373:127-134.
    • (1999) Eur J Pharmacol , vol.373 , pp. 127-134
    • Roth, J.D.1    Rowland, N.E.2
  • 67
    • 49449114438 scopus 로고    scopus 로고
    • Antiobesity effects of the beta-cell hormone amylin in combination with phenteramine or sibutramine in diety-induced obese rats
    • Roth J.D., Trevaskis J.L., Wilson J., Lei C., Athanacio J., Mack C., et al. Antiobesity effects of the beta-cell hormone amylin in combination with phenteramine or sibutramine in diety-induced obese rats. Int J Obesity 2008, 32:1201-1210.
    • (2008) Int J Obesity , vol.32 , pp. 1201-1210
    • Roth, J.D.1    Trevaskis, J.L.2    Wilson, J.3    Lei, C.4    Athanacio, J.5    Mack, C.6
  • 68
    • 0036136039 scopus 로고    scopus 로고
    • Effects of the cannabinoid receptor antagonist SR141716, alone and in combination with dexfenfluramine or naloxone, on food intake in rats
    • Rowland N.E., Mukherjee M., Robertson K. Effects of the cannabinoid receptor antagonist SR141716, alone and in combination with dexfenfluramine or naloxone, on food intake in rats. Psychopharmacology 2001, 159:111-116.
    • (2001) Psychopharmacology , vol.159 , pp. 111-116
    • Rowland, N.E.1    Mukherjee, M.2    Robertson, K.3
  • 69
    • 7144227374 scopus 로고    scopus 로고
    • Serotonergic control of the organization of feeding and satiety
    • Simansky K.J. Serotonergic control of the organization of feeding and satiety. Behav Brain Res 1996, 73:37-42.
    • (1996) Behav Brain Res , vol.73 , pp. 37-42
    • Simansky, K.J.1
  • 70
    • 58549094969 scopus 로고    scopus 로고
    • Treatment of chronic pruritus with the selective serotonin re-uptake inhibitors paroxetine and fluvoxamine: results of an open-labelled, two-arm proof-of-concept study
    • Ständer S., Böckenholt B., Schürmeyer-Horst F., Weishaupt C., Heuft G., Luger T.A., et al. Treatment of chronic pruritus with the selective serotonin re-uptake inhibitors paroxetine and fluvoxamine: results of an open-labelled, two-arm proof-of-concept study. Acta Derm Venereol 2009, 89:45-51.
    • (2009) Acta Derm Venereol , vol.89 , pp. 45-51
    • Ständer, S.1    Böckenholt, B.2    Schürmeyer-Horst, F.3    Weishaupt, C.4    Heuft, G.5    Luger, T.A.6
  • 71
    • 47549085721 scopus 로고    scopus 로고
    • 1 receptor antagonist and selective serotonin reuptake inhibitor in antidepressant behavioral tests
    • 1 receptor antagonist and selective serotonin reuptake inhibitor in antidepressant behavioral tests. Eur J Pharmacol 2008, 589:149-156.
    • (2008) Eur J Pharmacol , vol.589 , pp. 149-156
    • Takahashi, E.1    Katayama, M.2    Niimi, K.3    Itakura, C.4
  • 72
    • 34948844053 scopus 로고    scopus 로고
    • Acute anorectic response to cannabinoid receptor antagonist/inverse agonist AM 251 in rat: indirect behavioural mediation
    • Tallett A.J., Blundell J.E., Rodgers R.J. Acute anorectic response to cannabinoid receptor antagonist/inverse agonist AM 251 in rat: indirect behavioural mediation. Behav Pharmacol 2007, 18:591-600.
    • (2007) Behav Pharmacol , vol.18 , pp. 591-600
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 73
    • 34948850289 scopus 로고    scopus 로고
    • Grooming, scratching and feeding: role of response competition in acute anorectic response to rimonabant in male rats
    • Tallett A.J., Blundell J.E., Rodgers R.J. Grooming, scratching and feeding: role of response competition in acute anorectic response to rimonabant in male rats. Psychopharmacology 2007, 195:27-39.
    • (2007) Psychopharmacology , vol.195 , pp. 27-39
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 74
    • 38049095527 scopus 로고    scopus 로고
    • Behaviourally-selective hypophagic effects of naloxone in non-deprived male rats presented with palatable food
    • Tallett A.J., Blundell J.E., Rodgers R.J. Behaviourally-selective hypophagic effects of naloxone in non-deprived male rats presented with palatable food. Behav Brain Res 2008, 187:417-427.
    • (2008) Behav Brain Res , vol.187 , pp. 417-427
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 75
    • 43549107263 scopus 로고    scopus 로고
    • Endogenous opioids and cannabinoids: system interactions in the regulation of appetite, grooming and scratching
    • Tallett A.J., Blundell J.E., Rodgers R.J. Endogenous opioids and cannabinoids: system interactions in the regulation of appetite, grooming and scratching. Physiol Behav 2008, 94:422-431.
    • (2008) Physiol Behav , vol.94 , pp. 422-431
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 76
    • 57449096564 scopus 로고    scopus 로고
    • Effects of acute low-dose combined treatment with naloxone and AM 251 on food intake, feeding behaviour and weight gain in rats
    • Tallett A.J., Blundell J.E., Rodgers R.J. Effects of acute low-dose combined treatment with naloxone and AM 251 on food intake, feeding behaviour and weight gain in rats. Pharmacol Biochem Behav 2009, 91:358-366.
    • (2009) Pharmacol Biochem Behav , vol.91 , pp. 358-366
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 77
    • 62749111306 scopus 로고    scopus 로고
    • Night & day: diurnal differences in the behavioural satiety sequence in male rats
    • Tallett A.J., Blundell J.E., Rodgers R.J. Night & day: diurnal differences in the behavioural satiety sequence in male rats. Physiol Behav 2009, 97:125-130.
    • (2009) Physiol Behav , vol.97 , pp. 125-130
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 78
    • 59649089219 scopus 로고    scopus 로고
    • Sibutramine-induced anorexia: potent, dose-dependent and behaviourally-selective profile in male rats
    • Tallett A.J., Blundell J.E., Rodgers R.J. Sibutramine-induced anorexia: potent, dose-dependent and behaviourally-selective profile in male rats. Behav Brain Res 2009, 198:359-365.
    • (2009) Behav Brain Res , vol.198 , pp. 359-365
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 79
    • 70649091995 scopus 로고    scopus 로고
    • Sibutramine & naloxone: infra-additive interaction in the regulation of appetite? Behav Brain Res.
    • Tallett AJ, Blundell JE, Rodgers RJ. Sibutramine & naloxone: infra-additive interaction in the regulation of appetite? Behav Brain Res. 2010;174-81.
    • (2010) , pp. 174-81
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 81
    • 29244443673 scopus 로고    scopus 로고
    • Effects of amylin on feeding of goldfish: interactions with CCK
    • Thavanathan R., Volkoff H. Effects of amylin on feeding of goldfish: interactions with CCK. Regulat Peptides 2006, 133:90-96.
    • (2006) Regulat Peptides , vol.133 , pp. 90-96
    • Thavanathan, R.1    Volkoff, H.2
  • 82
    • 0037294538 scopus 로고    scopus 로고
    • 1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions
    • 1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions. Brit J Pharmacol 2003, 138:544-553.
    • (2003) Brit J Pharmacol , vol.138 , pp. 544-553
    • Tzavara, E.T.1    Davis, R.J.2    Perry, K.W.3    Li, X.4    Salhoff, C.5    Bymaster, F.P.6
  • 84
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Van Gaal L.F., Rissanen A.M., Scheen A.J., Ziegler O., Rossner S. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005, 365:1389-1397.
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 85
    • 40949112752 scopus 로고    scopus 로고
    • Therapeutic targeting of the endocannabinoid signaling system: drugs for obesity and the metabolic syndrome
    • Vemuri V.K., Janero D.R., Makriyannis A. Therapeutic targeting of the endocannabinoid signaling system: drugs for obesity and the metabolic syndrome. Physiol Behav 2008, 93:671-686.
    • (2008) Physiol Behav , vol.93 , pp. 671-686
    • Vemuri, V.K.1    Janero, D.R.2    Makriyannis, A.3
  • 86
  • 87
    • 0028893275 scopus 로고
    • Isobolographic assessment of the effects of combinations of phenylpropanolamine and fenfluramine on food intake in rats
    • Wellman P.J., Tow S., McMahon L. Isobolographic assessment of the effects of combinations of phenylpropanolamine and fenfluramine on food intake in rats. Pharamcol Biochem Behav 1995, 50:287-291.
    • (1995) Pharamcol Biochem Behav , vol.50 , pp. 287-291
    • Wellman, P.J.1    Tow, S.2    McMahon, L.3
  • 88
    • 77957750858 scopus 로고
    • Pharmacological and behavioural examination of the defensive reactions of laboratory mice to the calls of the Tawny owl. PhD thesis, School of Psychology, University of Leeds.
    • Weiss SM. Pharmacological and behavioural examination of the defensive reactions of laboratory mice to the calls of the Tawny owl. PhD thesis, 1995, School of Psychology, University of Leeds.
    • (1995)
    • Weiss, S.M.1
  • 89
  • 90
    • 0022504236 scopus 로고
    • Approaches to the study of drug interactions in behavioral pharmacology
    • Wessinger W.D. Approaches to the study of drug interactions in behavioral pharmacology. Neurosci Biobehav Revs 1986, 10:103-113.
    • (1986) Neurosci Biobehav Revs , vol.10 , pp. 103-113
    • Wessinger, W.D.1
  • 91
    • 0036361973 scopus 로고    scopus 로고
    • 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine
    • 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine. Pharmacol Biochem Behav 2002, 71:341-348.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 341-348
    • Williams, C.M.1    Kirkham, T.C.2
  • 92
    • 0004318660 scopus 로고    scopus 로고
    • Obesity: preventing and managing the global epidemic
    • ISBN 92 4 120894 5, World Health Organisation
    • World Health Organisation Obesity: preventing and managing the global epidemic. Report of a WHO consultation. WHO Technical Report Series No. 84 2000, ISBN 92 4 120894
    • (2000) Report of a WHO consultation. WHO Technical Report Series No. 84


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.