Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice

European Journal of Pharmacology

Volumn 648, Issue 1-3, 2010, Pages 179-187

  Yamabe, Noriko ^a   Noh, Jeong Sook ^a   Park, Chan Hum ^a   Kang, Ki Sung ^a   Shibahara, Naotoshi ^a   Tanaka, Takashi ^b   Yokozawa, Takako ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Advanced glycation endproducts; Db db mice; Dyslipidemia; Hyperglycemia; Loganin; Oxidative stress

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; BIOLOGICAL MARKER; CHOLESTEROL; CYCLOOXYGENASE 2; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; LOGANIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; REACTIVE OXYGEN METABOLITE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR RELA; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DYSLIPIDEMIA; FLUID INTAKE; FOOD INTAKE; GENE EXPRESSION; HYPERGLYCEMIA; KIDNEY INJURY; LIPID LIVER LEVEL; LIPID METABOLISM; LIPOGENESIS; LIVER INJURY; LIVER PROTECTION; LIVER WEIGHT; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WEIGHT GAIN;

ANIMALS; BIOLOGICAL MARKERS; BODY WEIGHT; CHOLESTEROL; CORNUS; CYCLOOXYGENASE 2; DIABETES MELLITUS, TYPE 2; DRINKING; FATTY ACIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; GLYCOSYLATION END PRODUCTS, ADVANCED; HEMATOLOGIC TESTS; INFLAMMATION; IRIDOIDS; KIDNEY; LIPID METABOLISM; LIVER; LYSINE; MALE; MICE; NITRIC OXIDE SYNTHASE TYPE II; ORGAN SIZE; OXIDATIVE STRESS; PPAR ALPHA; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTOR RELA; TRIGLYCERIDES;

EID: 77957749279     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.08.044     Document Type: Article

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