Suberoylanilide hydroxamic acid induces apoptosis and sub-G1 arrest of 320 HSR colon cancer cells

Journal of Biomedical Science

Volumn 17, Issue 1, 2010, Pages

  Sun, Pei Chang ^a   Tzao, Ching ^a   Chen, Ban Hen ^a   Liu, Chen Wei ^a   Yu, Cheng Ping ^a   Jin, Jong Shiaw ^a  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; KI 67 ANTIGEN; PROTEIN BCL XL; PROTEIN P21; PROTEIN P53; SURVIVIN; VORINOSTAT; ANTINEOPLASTIC AGENT; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; VASCULOTROPIN A;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CHEMOSENSITIVITY; COLON ADENOCARCINOMA; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; FLUORESCENCE ACTIVATED CELL SORTING; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; ADJUVANT CHEMOTHERAPY; CELL SEPARATION; DRUG EFFECT; FLOW CYTOMETRY; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SEPARATION; CHEMOTHERAPY, ADJUVANT; FLOW CYTOMETRY; G1 PHASE; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77957737244     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-17-76     Document Type: Article

References (24)

1. Histone acetylation and histone deacetylation. K Ito IM Adcock, Mol Biotechnol 2002 20 99 106 10.1385/MB:20:1:099 11876304
2. Roles of histone acetyltransferases and deacetylases in gene regulation. MH Kuo CD Allis, Bioassays 1998 20 615 626 10.1002/(SICI)1521-1878(199808)20: 8<615::AID-BIES4>3.0.CO;2-H
3. Histone deacetylase inhibitors as new cancer drugs. PA Marks VM Richon R Breslow RA Rifkind, Curr Opin Oncol 2001 13 477 483 10.1097/00001622-200111000- 00010 11673688
4. Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents. DH Kim M Kim HJ Kwon, J Biochem Mol Biol 2003 36 110 119 12542981
5. Estrogen and antiestrogen-dependent regulation of breast cancer cell proliferation in multicellular spheroids: Influence of cell microenvironment. I Truchet S Jozan S Baron C Frongia P Balaguer H Richard-Foy A Valette, Int J Oncol 2008 32 1033 1039 18425329
6. Antitumor activity of suberoylanilide hydroxamic acid against thyroid cancer cell lines in vitro and in vivo. QT Luong J O'Kelly GD Braunstein JM Hershman HP Koeffler, Clin Cancer Res 2006 12 5570 5577 10.1158/1078-0432.CCR- 06-0367 17000694
7. Cell cycle and apoptotic effects of SAHA are regulated by the cellular microenvironment in HCT116 multicellular tumour spheroids. V Lobjois C Frongia S Jozan I Truchet A Valette, Eur J Cancer 2009 45 2402 2411 10.1016/j.ejca.2009. 05.026 19553104
8. Targeted therapy for advanced colorectal cancer-more is not always better. RJ Mayer, N Engl J Med 2009 360 623 625 10.1056/NEJMe0809343 19196680
9. Functional outcome following restorative rectal cancer surgery. AP Zbar PJ Kennedy V Singh, Acta Chir Iugosl 2009 56 9 16 10.2298/ACI0902009Z 19780324
10. Inhibitors of histone deacetylase as new anticancer agents. M Jung, Curr Med Chem 2001 8 1505 1511 11562279
11. Histone-deacetylase inhibitors for the treatment of cancer. RK Lindemann B Gabrielli RW Johnstone, Cell Cycle 2004 3 779 788 15153801
12. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation. Y Takada A Gillenwater H Ichikawa BB Aggarwal, J Biol Chem 2006 281 5612 5622 10.1074/jbc.M507213200 16377638 (Pubitemid 43847658)
13. Activation of mitochondrial pathway is crucial for tumor selective induction of apoptosis by LAQ824. S Wang Y Yan-Neale R Cai I Alimov D Cohen, Cell Cycle 2006 5 1662 1668 16861932
14. Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. VM Richon TW Sandhoff RA Rifkind PA Marks, Proc Natl Acad Sci USA 2000 97 10014 10019 10.1073/pnas.180316197 10954755
15. Induction of polyploidy by histone deacetylase inhibitor: a pathway for antitumor effects. WS Xu G Perez L Ngo CY Gui PA Marks, Cancer Res 2005 65 7832 7839 10.1158/0008-5472.CAN-04-4313 16140952
16. Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells. DM Nguyen WD Schrump GA Chen W Tsai P Nguyen JB Trepel DS Schrump, Clin Cancer Res 2004 10 1813 1825 10.1158/1078-0432.CCR-0901-3 15014036
17. Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer. WK Kelly OA O'Connor LM Krug JH Chiao M Heaney T Curley B MacGregore-Cortelli W Tong JP Secrist L Schwartz S Richardson E Chu S Olgac PA Marks H Scher VM Richon, J Clin Oncol 2005 23 3923 3931 10.1200/JCO.2005.14.167 15897550
18. Histone deacetylase inhibitors profoundly decrease proliferation of human lymphoid cancer cell lines. S Sakajiri T Kumagai N Kawamata T Saitoh JW Said HP Koeffler, Exp Hematol 2005 33 53 61 10.1016/j.exphem.2004.09.008 15661398
19. Activity of suberoylanilide hydroxamic acid against human breast cancer cells with amplification of Her-2. P Bali M Pranpat R Swaby W Fiskus H Yamaguchi M Balasis K Rocha HG Wang V Richon K Bhalla, Clin Cancer Res 2005 11 6382 6389 10.1158/1078-0432.CCR-05-0344 16144943
20. Suberoylanilide hydroxamic acid combined with gemcitabine enhances apoptosis in non-small cell lung cancer. BK Rundall CE Denlinger DR Jones, Surgery 2005 138 360 367 10.1016/j.surg.2005.06.016 16153448
21. Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells. N Takai JC Desmond T Kumagai D Gui JW Said S Whittaker I Miyakawa HP Koeffler, Clin Cancer Res 2004 10 1141 1149 10.1158/1078-0432. CCR-03-0100 14871994
22. Human ovarian carcinoma cells: histone deacetylase inhibitors exhibit antiproliferative activity and potently induce apoptosis. N Takai N Kawamata D Gui JW Said I Miyakawa HP Koeffler, Cancer 2004 101 2760 2770 10.1002/cncr.20709 15536623
23. An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner. EJ Noh DS Lim G Jeong JS Lee, Biochem Biophys Res Commun 2009 378 326 331 10.1016/j.bbrc.2008.11.057 19038231
24. The case for survivin as a regulator of microtubule dynamics and cell-death decisions. DC Altieri, Curr Opin Cell Biol 2006 18 609 615 10.1016/j.ceb.2006.08.015 16934447