-
1
-
-
0033800091
-
Multicellular resistance: a paradigm for clinical resistance?
-
Desoize B., and Jardillier J. Multicellular resistance: a paradigm for clinical resistance?. Crit Rev Oncol Hematol 36 2-3 (2000) 193-207
-
(2000)
Crit Rev Oncol Hematol
, vol.36
, Issue.2-3
, pp. 193-207
-
-
Desoize, B.1
Jardillier, J.2
-
2
-
-
36849009670
-
Experimental anti-tumour therapy in 3-D: spheroids-old hat or new challenge?
-
Friedrich J., Ebner R., and Kunz-Schughart L.A. Experimental anti-tumour therapy in 3-D: spheroids-old hat or new challenge?. Int J Radiat Biol 83 11-12 (2007) 849-871
-
(2007)
Int J Radiat Biol
, vol.83
, Issue.11-12
, pp. 849-871
-
-
Friedrich, J.1
Ebner, R.2
Kunz-Schughart, L.A.3
-
3
-
-
0024281372
-
Cell and environment interactions in tumour microregions: the multicell spheroid model
-
Sutherland R.M. Cell and environment interactions in tumour microregions: the multicell spheroid model. Science 240 4849 (1988) 177-184
-
(1988)
Science
, vol.240
, Issue.4849
, pp. 177-184
-
-
Sutherland, R.M.1
-
4
-
-
25144506210
-
A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs
-
Mellor H.R., Ferguson D.J., and Callaghan R. A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs. Br J Cancer 93 3 (2005) 302-309
-
(2005)
Br J Cancer
, vol.93
, Issue.3
, pp. 302-309
-
-
Mellor, H.R.1
Ferguson, D.J.2
Callaghan, R.3
-
5
-
-
0034765511
-
Histone deacetylase inhibitors as new cancer drugs
-
Marks P.A., Richon V.M., Breslow R., and Rifkind R.A. Histone deacetylase inhibitors as new cancer drugs. Curr Opin Oncol 13 6 (2001) 477-483
-
(2001)
Curr Opin Oncol
, vol.13
, Issue.6
, pp. 477-483
-
-
Marks, P.A.1
Richon, V.M.2
Breslow, R.3
Rifkind, R.A.4
-
6
-
-
34547864236
-
Histone deacetylase inhibitors: molecular mechanisms of action
-
Xu W.S., Parmigiani R.B., and Marks P.A. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 26 37 (2007) 5541-5552
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5541-5552
-
-
Xu, W.S.1
Parmigiani, R.B.2
Marks, P.A.3
-
7
-
-
33847258674
-
Discovery and development of SAHA as an anticancer agent
-
Marks P.A. Discovery and development of SAHA as an anticancer agent. Oncogene 26 9 (2007) 1351-1356
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1351-1356
-
-
Marks, P.A.1
-
8
-
-
3042785975
-
A review of depsipeptide and other histone deacetylase inhibitors in clinical trials
-
Piekarz R., and Bates S. A review of depsipeptide and other histone deacetylase inhibitors in clinical trials. Curr Pharm Des 10 19 (2004) 2289-2298
-
(2004)
Curr Pharm Des
, vol.10
, Issue.19
, pp. 2289-2298
-
-
Piekarz, R.1
Bates, S.2
-
9
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
-
Duvic M., Talpur R., Ni X., et al. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 109 1 (2007) 31-39
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
-
10
-
-
34249937594
-
Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumours: a clinical and translational study
-
Munster P., Marchion D., Bicaku E., et al. Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumours: a clinical and translational study. J Clin Oncol 25 15 (2007) 1979-1985
-
(2007)
J Clin Oncol
, vol.25
, Issue.15
, pp. 1979-1985
-
-
Munster, P.1
Marchion, D.2
Bicaku, E.3
-
11
-
-
33747836834
-
Activation of mitochondrial pathway is crucial for tumour selective induction of apoptosis by LAQ824
-
Wang S., Yan-Neale Y., Cai R., Alimov I., and Cohen D. Activation of mitochondrial pathway is crucial for tumour selective induction of apoptosis by LAQ824. Cell Cycle 5 15 (2006) 1662-1668
-
(2006)
Cell Cycle
, vol.5
, Issue.15
, pp. 1662-1668
-
-
Wang, S.1
Yan-Neale, Y.2
Cai, R.3
Alimov, I.4
Cohen, D.5
-
12
-
-
33646851955
-
Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation
-
Takada Y., Gillenwater A., Ichikawa H., and Aggarwal B.B. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation. J Biol Chem 281 9 (2006) 5612-5622
-
(2006)
J Biol Chem
, vol.281
, Issue.9
, pp. 5612-5622
-
-
Takada, Y.1
Gillenwater, A.2
Ichikawa, H.3
Aggarwal, B.B.4
-
13
-
-
20044390016
-
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors
-
Ungerstedt J.S., Sowa Y., Xu W.S., et al. Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors. Proc Natl Acad Sci USA 102 3 (2005) 673-678
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.3
, pp. 673-678
-
-
Ungerstedt, J.S.1
Sowa, Y.2
Xu, W.S.3
-
14
-
-
0042090495
-
Novel mechanisms of apoptosis induced by histone deacetylase inhibitors
-
Peart M.J., Tainton K.M., Ruefli A.A., et al. Novel mechanisms of apoptosis induced by histone deacetylase inhibitors. Cancer Res 63 15 (2003) 4460-4471
-
(2003)
Cancer Res
, vol.63
, Issue.15
, pp. 4460-4471
-
-
Peart, M.J.1
Tainton, K.M.2
Ruefli, A.A.3
-
15
-
-
13944284147
-
Specific and redundant functions of histone deacetylases in regulation of cell cycle and apoptosis
-
Zhu P., Huber E., Kiefer F., and Gottlicher M. Specific and redundant functions of histone deacetylases in regulation of cell cycle and apoptosis. Cell cycle 3 10 (2004) 1240-1242
-
(2004)
Cell cycle
, vol.3
, Issue.10
, pp. 1240-1242
-
-
Zhu, P.1
Huber, E.2
Kiefer, F.3
Gottlicher, M.4
-
16
-
-
2942753983
-
Spheroid preparation from hanging drops: characterization of a model of brain tumour invasion
-
Del Duca D., Werbowetski T., and Del Maestro R.F. Spheroid preparation from hanging drops: characterization of a model of brain tumour invasion. J Neurooncol 67 3 (2004) 295-303
-
(2004)
J Neurooncol
, vol.67
, Issue.3
, pp. 295-303
-
-
Del Duca, D.1
Werbowetski, T.2
Del Maestro, R.F.3
-
17
-
-
45849129851
-
Estrogen and antiestrogen-dependent regulation of breast cancer cell proliferation in multicellular spheroids: influence of cell microenvironment
-
Truchet I., Jozan S., Baron S., et al. Estrogen and antiestrogen-dependent regulation of breast cancer cell proliferation in multicellular spheroids: influence of cell microenvironment. Int J Oncol 32 5 (2008) 1033-1039
-
(2008)
Int J Oncol
, vol.32
, Issue.5
, pp. 1033-1039
-
-
Truchet, I.1
Jozan, S.2
Baron, S.3
-
18
-
-
0035511646
-
Activation of p90RSK and growth stimulation of multicellular tumour spheroids are dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
-
Sauer H., Klimm B., Hescheler J., and Wartenberg M. Activation of p90RSK and growth stimulation of multicellular tumour spheroids are dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP. Faseb J 15 13 (2001) 2539-2541
-
(2001)
Faseb J
, vol.15
, Issue.13
, pp. 2539-2541
-
-
Sauer, H.1
Klimm, B.2
Hescheler, J.3
Wartenberg, M.4
-
20
-
-
0034730127
-
Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
-
Richon V.M., Sandhoff T.W., Rifkind R.A., and Marks P.A. Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. Proc Natl Acad Sci USA 97 18 (2000) 10014-10019
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.18
, pp. 10014-10019
-
-
Richon, V.M.1
Sandhoff, T.W.2
Rifkind, R.A.3
Marks, P.A.4
-
21
-
-
33750611276
-
The case for survivin as a regulator of microtubule dynamics and cell-death decisions
-
Altieri D.C. The case for survivin as a regulator of microtubule dynamics and cell-death decisions. Curr Opin Cell Biol 18 6 (2006) 609-615
-
(2006)
Curr Opin Cell Biol
, vol.18
, Issue.6
, pp. 609-615
-
-
Altieri, D.C.1
-
22
-
-
57749189353
-
An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner
-
Noh E.J., Lim D.S., Jeong G., and Lee J.S. An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner. Biochem Biophys Res Commun 378 3 (2009) 326-331
-
(2009)
Biochem Biophys Res Commun
, vol.378
, Issue.3
, pp. 326-331
-
-
Noh, E.J.1
Lim, D.S.2
Jeong, G.3
Lee, J.S.4
-
23
-
-
0037434409
-
Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma
-
Grabowski P., Kuhnel T., Muhr-Wilkenshoff F., et al. Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma. Br J Cancer 88 1 (2003) 115-119
-
(2003)
Br J Cancer
, vol.88
, Issue.1
, pp. 115-119
-
-
Grabowski, P.1
Kuhnel, T.2
Muhr-Wilkenshoff, F.3
-
24
-
-
0035845541
-
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
-
Ruefli A.A., Ausserlechner M.J., Bernhard D., et al. The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc Natl Acad Sci USA 98 19 (2001) 10833-10838
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.19
, pp. 10833-10838
-
-
Ruefli, A.A.1
Ausserlechner, M.J.2
Bernhard, D.3
-
25
-
-
36148966966
-
R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoural activity against solid and haematological malignancies
-
Arts J., Angibaud P., Marien A., et al. R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoural activity against solid and haematological malignancies. Br J Cancer 97 10 (2007) 1344-1353
-
(2007)
Br J Cancer
, vol.97
, Issue.10
, pp. 1344-1353
-
-
Arts, J.1
Angibaud, P.2
Marien, A.3
-
26
-
-
24744434639
-
Induction of polyploidy by histone deacetylase inhibitor: a pathway for antitumour effects
-
Xu W.S., Perez G., Ngo L., Gui C.Y., and Marks P.A. Induction of polyploidy by histone deacetylase inhibitor: a pathway for antitumour effects. Cancer Res 65 17 (2005) 7832-7839
-
(2005)
Cancer Res
, vol.65
, Issue.17
, pp. 7832-7839
-
-
Xu, W.S.1
Perez, G.2
Ngo, L.3
Gui, C.Y.4
Marks, P.A.5
-
27
-
-
0038677606
-
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation
-
Shin H.J., Baek K.H., Jeon A.H., et al. Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. Oncogene 22 25 (2003) 3853-3858
-
(2003)
Oncogene
, vol.22
, Issue.25
, pp. 3853-3858
-
-
Shin, H.J.1
Baek, K.H.2
Jeon, A.H.3
-
28
-
-
0042704723
-
Tumour cell-selective cytotoxicity by targeting cell cycle checkpoints
-
Warrener R., Beamish H., Burgess A., et al. Tumour cell-selective cytotoxicity by targeting cell cycle checkpoints. Faseb J 17 11 (2003) 1550-1552
-
(2003)
Faseb J
, vol.17
, Issue.11
, pp. 1550-1552
-
-
Warrener, R.1
Beamish, H.2
Burgess, A.3
-
29
-
-
0035147369
-
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases
-
Taddei A., Maison C., Roche D., and Almouzni G. Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. Nat Cell Biol 3 2 (2001) 114-120
-
(2001)
Nat Cell Biol
, vol.3
, Issue.2
, pp. 114-120
-
-
Taddei, A.1
Maison, C.2
Roche, D.3
Almouzni, G.4
-
30
-
-
0038079767
-
The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1
-
Rosato R.R., Almenara J.A., and Grant S. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1. Cancer Res 63 13 (2003) 3637-3645
-
(2003)
Cancer Res
, vol.63
, Issue.13
, pp. 3637-3645
-
-
Rosato, R.R.1
Almenara, J.A.2
Grant, S.3
-
31
-
-
4644304383
-
Histone deacetylase inhibitors specifically kill nonproliferating tumour cells
-
Burgess A., Ruefli A., Beamish H., et al. Histone deacetylase inhibitors specifically kill nonproliferating tumour cells. Oncogene 23 40 (2004) 6693-6701
-
(2004)
Oncogene
, vol.23
, Issue.40
, pp. 6693-6701
-
-
Burgess, A.1
Ruefli, A.2
Beamish, H.3
-
32
-
-
0034802325
-
Up-regulation of p21(WAF1/CIP1) by histone deacetylase inhibitors reduces their cytotoxicity
-
Burgess A.J., Pavey S., Warrener R., et al. Up-regulation of p21(WAF1/CIP1) by histone deacetylase inhibitors reduces their cytotoxicity. Mol Pharmacol 60 4 (2001) 828-837
-
(2001)
Mol Pharmacol
, vol.60
, Issue.4
, pp. 828-837
-
-
Burgess, A.J.1
Pavey, S.2
Warrener, R.3
-
33
-
-
3142602957
-
Analysis of the horseradish peroxidase/indole-3-acetic acid combination in a three-dimensional tumour model
-
Tupper J., Greco O., Tozer G.M., and Dachs G.U. Analysis of the horseradish peroxidase/indole-3-acetic acid combination in a three-dimensional tumour model. Cancer Gene Ther 11 7 (2004) 508-513
-
(2004)
Cancer Gene Ther
, vol.11
, Issue.7
, pp. 508-513
-
-
Tupper, J.1
Greco, O.2
Tozer, G.M.3
Dachs, G.U.4
-
34
-
-
1842481018
-
Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells
-
Nguyen D.M., Schrump W.D., Chen G.A., et al. Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells. Clin Cancer Res 10 5 (2004) 1813-1825
-
(2004)
Clin Cancer Res
, vol.10
, Issue.5
, pp. 1813-1825
-
-
Nguyen, D.M.1
Schrump, W.D.2
Chen, G.A.3
|