-
1
-
-
0017171175
-
Prolonged tumor dormancy by prevention of neovascularization in the vitreous
-
Brem S, Brem H, Folkman J, et al. Prolonged tumor dormancy by prevention of neovascularization in the vitreous. Cancer Res 1976; 36: 2807-12.
-
(1976)
Cancer Res
, vol.36
, pp. 2807-2812
-
-
Brem, S.1
Brem, H.2
Folkman, J.3
-
2
-
-
0022648938
-
How is blood vessel growth regulated in normal and neoplastic tissue?
-
Folkman J. How is blood vessel growth regulated in normal and neoplastic tissue? Cancer Res 1986; 46: 467-73.
-
(1986)
Cancer Res
, vol.46
, pp. 467-473
-
-
Folkman, J.1
-
3
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet P. Angiogenesis in health and disease. Nature Med 2003; 9: 653-60.
-
(2003)
Nature Med
, vol.9
, pp. 653-660
-
-
Carmeliet, P.1
-
4
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med 2003; 9: 677-84.
-
(2003)
Nat Med
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
5
-
-
3142628260
-
The relationship between hypoxia and angiogenesis
-
Moeller BJ, Cao Y, Vujaskovic Z, et al. The relationship between hypoxia and angiogenesis. Sem Radiat Oncol 2004; 14: 215-21.
-
(2004)
Sem Radiat Oncol
, vol.14
, pp. 215-221
-
-
Moeller, B.J.1
Cao, Y.2
Vujaskovic, Z.3
-
7
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Revs Cancer 2003; 3: 401-10.
-
(2003)
Nat Revs Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
8
-
-
12244292196
-
Differentiation and definition of vascular-targeted therapies
-
Siemann DW, Bibby MC, Dark GG, et al. Differentiation and definition of vascular-targeted therapies. Clin Cancer Res 2005; 11: 416-20.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 416-420
-
-
Siemann, D.W.1
Bibby, M.C.2
Dark, G.G.3
-
9
-
-
33748869678
-
Pathophysiological effects of vascular-targeting agents and the implications for combination with conventional therapies
-
Horsman MR, Siemann DW. Pathophysiological effects of vascular-targeting agents and the implications for combination with conventional therapies. Cancer Res 2006; 66: 11520-39.
-
(2006)
Cancer Res
, vol.66
, pp. 11520-11539
-
-
Horsman, M.R.1
Siemann, D.W.2
-
10
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
Kerbel R, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Revs Cancer 2002; 2: 727-39.
-
(2002)
Nat Revs Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
11
-
-
77951879926
-
Antiangiogenic drugs in oncology: A focus on drug safety and the elderly - A mini review
-
Boehm S, Rothermundt C, Hess D, et al. Antiangiogenic drugs in oncology: a focus on drug safety and the elderly - a mini review. Gerontology 2010; 56: 303-9.
-
(2010)
Gerontology
, vol.56
, pp. 303-309
-
-
Boehm, S.1
Rothermundt, C.2
Hess, D.3
-
12
-
-
0034306873
-
Targeting tumor blood vessels: An adjuvant strategy for radiation therapy
-
Siemann DW, Warrington KH, Horsman MR. Targeting tumor blood vessels: an adjuvant strategy for radiation therapy. Radiother Oncol 2000; 57: 5-12.
-
(2000)
Radiother Oncol
, vol.57
, pp. 5-12
-
-
Siemann, D.W.1
Warrington, K.H.2
Horsman, M.R.3
-
13
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
DOI 10.1126/science.1082504
-
Garcia-Barros M, Paris F, Cordon-Cardo C, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003; 300: 1155-9. (Pubitemid 36583102)
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1155-1159
-
-
Garcia-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
Lyden, D.4
Rafii, S.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Kolesnick, R.8
-
14
-
-
0842311621
-
Vascular targeting agents as cancer therapeutics
-
Thorpe PE. Vascular targeting agents as cancer therapeutics. Clin Cancer Res 2004; 10: 415-27.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 415-427
-
-
Thorpe, P.E.1
-
17
-
-
0034472914
-
Combretastatins novel vascular targeting drugs for improving anti-cancer therapy
-
Horsman MR, Murata R, Breidahl T, et al. Combretastatins novel vascular targeting drugs for improving anti-cancer therapy. Advances Exper Med Biol 2000; 476: 311-23.
-
(2000)
Advances Exper Med Biol
, vol.476
, pp. 311-323
-
-
Horsman, M.R.1
Murata, R.2
Breidahl, T.3
-
18
-
-
69349095364
-
Anticancer strategies involving the vasculature
-
Heath VL, Bicknell R. Anticancer strategies involving the vasculature. Nat Revs Clin Oncol 2009; 6: 395-404.
-
(2009)
Nat Revs Clin Oncol
, vol.6
, pp. 395-404
-
-
Heath, V.L.1
Bicknell, R.2
-
19
-
-
77951227230
-
Regulation of tumor angiogenesis by the local environment
-
Hall K, Ran S. Regulation of tumor angiogenesis by the local environment. Frontiers in Bioscience 2010; 15: 195-212.
-
(2010)
Frontiers in Bioscience
, vol.15
, pp. 195-212
-
-
Hall, K.1
Ran, S.2
-
20
-
-
33845524204
-
Role of tumor-associated macrophages in tumor progression and invasion
-
DOI 10.1007/s10555-006-9001-7, Special Issue on Pro-inflammatory Cytokines in Cancer
-
Mantovani A, Schioppa T, Porta C, et al. Role of tumor-associated macrophages in tumor progression and invasion. Cancer Mets Rev 2006; 25: 315-22. (Pubitemid 44922352)
-
(2006)
Cancer and Metastasis Reviews
, vol.25
, Issue.3
, pp. 315-322
-
-
Mantovani, A.1
Schioppa, T.2
Porta, C.3
Allavena, P.4
Sica, A.5
-
21
-
-
65549145501
-
Neutrophils: Key mediators of tumour angiogenesis
-
Tazzyman S, Lewis CE, Murdoch C. Neutrophils: key mediators of tumour angiogenesis. Int J Exp Pathol 2009; 90: 222-31.
-
(2009)
Int J Exp Pathol
, vol.90
, pp. 222-231
-
-
Tazzyman, S.1
Lewis, C.E.2
Murdoch, C.3
-
22
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic micro-environment of human tumors: a review. Cancer Res 1989; 49: 6449-65. (Pubitemid 20008770)
-
(1989)
Cancer Research
, vol.49
, Issue.23
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
23
-
-
33750727425
-
Tumour hypoxia - A characteristic feature with a complex molecular background
-
Eriksen JG, Horsman MR. Tumour hypoxia - a characteristic feature with a complex molecular background. Radiother Oncol 2006; 81: 119-21.
-
(2006)
Radiother Oncol
, vol.81
, pp. 119-121
-
-
Eriksen, J.G.1
Horsman, M.R.2
-
24
-
-
33749005405
-
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
-
DOI 10.1126/science.1127592
-
Shaked Y, Ciarrocchi A, Franco M, et al. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science 2006; 313: 1785-7. (Pubitemid 44454154)
-
(2006)
Science
, vol.313
, Issue.5794
, pp. 1785-1787
-
-
Shaked, Y.1
Ciarrocchi, A.2
Franco, M.3
Lee, C.R.4
Man, S.5
Cheung, A.M.6
Hicklin, D.J.7
Chaplin, D.8
Foster, F.S.9
Benezra, R.10
Kerbel, R.S.11
-
25
-
-
39849100541
-
Matrix-metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: Role of bone marrow-derived myelomonocytic cells
-
Ahn G-O, Brown JM. Matrix-metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell 2008; 13: 193-205.
-
(2008)
Cancer Cell
, vol.13
, pp. 193-205
-
-
Ahn, G.-O.1
Brown, J.M.2
-
26
-
-
0034796595
-
Normalizing tumor vasculature with antiangiogenic therapy: A new paradigm for combination therapy
-
Jain RK. Normalizing tumor vasculature with antiangiogenic therapy: a new paradigm for combination therapy. Nat Med 2001; 7: 987-9.
-
(2001)
Nat Med
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
27
-
-
19944422751
-
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
-
DOI 10.1016/j.ccr.2004.10.011, PII S1535610804003058
-
Winkler F, Kozin SV, Tong RT, et al. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell 2004; 6: 553-63. (Pubitemid 40017699)
-
(2004)
Cancer Cell
, vol.6
, Issue.6
, pp. 553-563
-
-
Winkler, F.1
Kozin, S.V.2
Tong, R.T.3
Chae, S.-S.4
Booth, M.F.5
Garkavtsev, I.6
Xu, L.7
Hicklin, D.J.8
Fukumura, D.9
Di Tomaso, E.10
Munn, L.L.11
Jain, R.K.12
-
28
-
-
69249150466
-
Biological mechanisms of bevacizumab-associated adverse events
-
Higa GM, Abraham J. Biological mechanisms of bevacizumab-associated adverse events. Expert Rev Anticancer Ther 2009; 9: 999-1007.
-
(2009)
Expert Rev Anticancer Ther
, vol.9
, pp. 999-1007
-
-
Higa, G.M.1
Abraham, J.2
-
29
-
-
70350724766
-
Thrombotic events in patients with cancer receiving antiangiogenesis agents
-
Zangari M, Fink LM, Elice F, et al. Thrombotic events in patients with cancer receiving antiangiogenesis agents. J Clin Oncol 2009; 27: 4865-73.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4865-4873
-
-
Zangari, M.1
Fink, L.M.2
Elice, F.3
-
30
-
-
4544277194
-
Combretastatin A4 phosphate: Background and current clinical status
-
Young SL, Chaplin DJ. Combretastatin A4 phosphate: background and current clinical status. Expert Opin Investig Drugs 2004; 13: 1171-82.
-
(2004)
Expert Opin Investig Drugs
, vol.13
, pp. 1171-1182
-
-
Young, S.L.1
Chaplin, D.J.2
-
32
-
-
77957741523
-
Physiological changes induced by combretastatin and their significance for the therapeutic application
-
Horsman MR, Schmidt AB, Nielsen T, et al. Physiological changes induced by combretastatin and their significance for the therapeutic application. Mol Cancer Ther 2007; 6: 3435S.
-
(2007)
Mol Cancer Ther
, vol.6
-
-
Horsman, M.R.1
Schmidt, A.B.2
Nielsen, T.3
-
33
-
-
70449109160
-
Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats
-
Ke Q, Bodyak N, Rigor DL, et al. Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats. Vasc Pharmacol 2009; 51: 337-43.
-
(2009)
Vasc Pharmacol
, vol.51
, pp. 337-343
-
-
Ke, Q.1
Bodyak, N.2
Rigor, D.L.3
-
34
-
-
70349338935
-
AVE8062: A new combretastatin derivative vascular disrupting agent
-
Delmonte A, Sessa C. AVE8062: a new combretastatin derivative vascular disrupting agent. Expert Opin Invest Drugs 2009; 18: 1541-8.
-
(2009)
Expert Opin Invest Drugs
, vol.18
, pp. 1541-1548
-
-
Delmonte, A.1
Sessa, C.2
-
35
-
-
74549118938
-
The development of the tumor vascular-disrupting agent ASA404 (vadimezan, DMXAA): Current status and future opportunities
-
Head M, Jameson MB. The development of the tumor vascular-disrupting agent ASA404 (vadimezan, DMXAA): current status and future opportunities. Expert Opin Invest Drugs 2009; 19: 295-304.
-
(2009)
Expert Opin Invest Drugs
, vol.19
, pp. 295-304
-
-
Head, M.1
Jameson, M.B.2
-
36
-
-
68049108414
-
Vascular disrupting agents: A novel mechanism of action in the battle against non-small cell lung cancer
-
Gridelli C, Rossi A, Maione P, et al. Vascular disrupting agents: a novel mechanism of action in the battle against non-small cell lung cancer. The Oncologist 2009; 14: 612-20.
-
(2009)
The Oncologist
, vol.14
, pp. 612-620
-
-
Gridelli, C.1
Rossi, A.2
Maione, P.3
-
37
-
-
40549125995
-
Phase I clinical evaluation of ZD6126, a novel vascular-targeting agent, in patients with solid tumors
-
LoRusso PM, Gadgeel SM, Wozniak A, et al. Phase I clinical evaluation of ZD6126, a novel vascular-targeting agent, in patients with solid tumors. Invest New Drugs 2008; 26: 159-67.
-
(2008)
Invest New Drugs
, vol.26
, pp. 159-167
-
-
LoRusso, P.M.1
Gadgeel, S.M.2
Wozniak, A.3
-
38
-
-
77956624019
-
A dose escalation, safety, and tolerability study of MN-029 in patients with advanced solid tumors
-
Traynor AM, Gordon MS, Alberti D, et al. A dose escalation, safety, and tolerability study of MN-029 in patients with advanced solid tumors. Invest New Drugs 2009; 28: 509-15.
-
(2009)
Invest New Drugs
, vol.28
, pp. 509-515
-
-
Traynor, A.M.1
Gordon, M.S.2
Alberti, D.3
-
39
-
-
0034759198
-
Improved tumor response by combining radiation and the vascular-damaging drug 5,6-dimethylxanthenone-4-acetic acid
-
Murata M, Siemann DW, Overgaard J, et al. Improved tumor response by combining radiation and the vascular-damaging drug 5,6-dimethylxanthenone-4- acetic acid. Radiat Res 2001; 156: 503-9. (Pubitemid 33027519)
-
(2001)
Radiation Research
, vol.156
, Issue.5 I
, pp. 503-509
-
-
Murata, R.1
Siemann, D.W.2
Overgaard, J.3
Horsman, M.R.4
-
40
-
-
0036891440
-
Combination of vascular targeting agents with thermal or radiation therapy
-
Horsman MR, Murata M. Combination of vascular targeting agents with thermal or radiation therapy. Int J Radiat Oncol Biol Phys 2002; 54: 1518-23.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1518-1523
-
-
Horsman, M.R.1
Murata, M.2
|