Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor β1

Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2003, Pages 1580-1588

  Ye, Liu ^a   Li, Yi Lin ^a   Mellström, Karin ^a   Mellin, Charlotta ^a   Bladh, Lars Göran ^a   Koehler, Konrad ^a   Garg, Neeraj ^a   Garcia Collazo, Ana Maria ^a   Litten, Chris ^a   Husman, Bolette ^a   Persson, Karina ^a   Ljunggren, Jan ^a   Grover, Gary ^b   Sleph, Paul G ^b   George, Rocco ^b   Malm, Johan ^a  

^a Karo Bio   (Sweden)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DIBROMO 4 [(4 HYDROXY 3 ISOPROPYLPHENOXY)PHENYL]ACETIC ACID; 3,5 DICHLORO 4 [(4 HYDROXY 3 ISOPROPYLPHENOXY)PHENYL]ACETIC ACID; ACETIC ACID; ALKALINE PHOSPHATASE; CHOLESTEROL; FORMIC ACID; HORMONE RECEPTOR STIMULATING AGENT; LIGAND; LIOTHYRONINE; PHENYLACETIC ACID DERIVATIVE; PROPIONIC ACID; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR AGONIST; THYROID HORMONE RECEPTOR ALPHA1; THYROID HORMONE RECEPTOR BETA1; THYROTROPIN; THYROXINE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BRAIN FUNCTION; CARDIOTOXICITY; CHOLESTEROL BLOOD LEVEL; DRUG SELECTIVITY; GENE EXPRESSION REGULATION; GROWTH REGULATION; HEART MUSCLE; HEART RATE; HOMEOSTASIS; HUMAN; HYDROGEN BOND; HYPERLIPIDEMIA; HYPERTHYROIDISM; INTESTINE CELL; LIGAND BINDING; LIVER; METABOLIC RATE; OBESITY; PROTEIN DOMAIN; RECEPTOR BINDING; REPORTER GENE; SKELETAL MUSCLE; STATISTICAL SIGNIFICANCE; STRUCTURE ACTIVITY RELATION; TACHYCARDIA; THYROID GLAND; X RAY CRYSTALLOGRAPHY;

ALKALINE PHOSPHATASE; ANIMALS; BINDING SITES; CHO CELLS; CHOLESTEROL; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; GENES, REPORTER; HEART RATE; HUMANS; LIGANDS; MALE; PHENYLACETATES; PROTEIN ISOFORMS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA; THYROTROPIN; TRIIODOTHYRONINE;

EID: 0037464499     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm021080f     Document Type: Article

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