Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms

BMC Structural Biology

Volumn 8, Issue , 2008, Pages

  Bleicher, Lucas ^a   Aparicio, Ricardo ^b   Nunes, Fabio M ^a   Martinez, Leandro ^b   Gomes Dias, Sandra M ^c   Figueira, Ana Carolina Migliorini ^a   Santos, Maria Auxiliadora Morim ^a   Venturelli, Walter H ^a   Da Silva, Rosangela ^d   Donate, Paulo Marcos ^a   Neves, Francisco A R ^e   Simeoni, Luiz A ^e   Baxter, John D ^f   Webb, Paul ^f   Skaf, Munir S ^b   Polikarpov, Igor ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c Department of Obstetrics Gynecology   (United States)

^d UNIVERSIDADE DE FRANCA   (Brazil)

^e UNIVERSITY OF BRASILIA   (Brazil)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DIMETHYL 4 (4' HYDROXY 3' ISOPROPYLBENZYL)PHENOXY ACETIC ACID; ARGININE; ASPARAGINE; ISOPROTEIN; PHENOXYACETIC ACID; SERINE; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; ACETIC ACID DERIVATIVE; GC 1 COMPOUND; LIGAND; PHENOL DERIVATIVE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SIMULATION; X RAY CRYSTALLOGRAPHY; BINDING SITE; BIOLOGICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; HELA CELL; METABOLISM;

ACETIC ACIDS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HELA CELLS; HUMANS; LIGANDS; MODELS, BIOLOGICAL; PHENOLS; PROTEIN ISOFORMS; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA;

EID: 43049106192     PISSN: None     EISSN: 14726807     Source Type: Journal    
DOI: 10.1186/1472-6807-8-8     Document Type: Article

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