NOC chemistry for tuberculosis - Further investigations on the structure-activity relationships of antitubercular isoxazole-3-carboxylic acid ester derivatives

ChemMedChem

Volumn 5, Issue 10, 2010, Pages 1667-1672

  Pieroni, Marco ^a   Lilienkampf, Annamaria ^a,b   Wang, Yuehong ^a   Wan, Baojie ^a   Cho, Sanghyun ^a   Franzblau, Scott G ^a   Kozikowski, Alan P ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Drug design; Drug discovery; Isoxazole derivatives; Tuberculosis

Indexed keywords

5 [[[N 2,8 BIS(TRIFLUOROMETHYL) 4 QUINOLINYL]AMINO]METHYL] 3 ISOXAZOLECARBOXYLIC ACID; ISOXAZOLE 3 CARBOXYLIC ACID ESTER DERIVATIVE; NITRILE OXIDE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CYCLOADDITION; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TUBERCULOSIS;

ANIMALS; ANTITUBERCULAR AGENTS; CARBOXYLIC ACIDS; CERCOPITHECUS AETHIOPS; DRUG DESIGN; HUMANS; MYCOBACTERIUM TUBERCULOSIS; OXAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCULOSIS; VERO CELLS;

EID: 77957671760     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201000169     Document Type: Article

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