메뉴 건너뛰기




Volumn 11, Issue 10, 2010, Pages 1135-1142

Thyroid hormone receptor and lipid regulation

Author keywords

Cholesterol; dyslipidemia; lipid metabolism; lipoprotein; selective modulation; thyroid hormone receptor; triglyceride

Indexed keywords

3,5 DIIODOTHYROPROPIONIC ACID; ATORVASTATIN; CHOLESTEROL; EPROTIROME; EZETIMIBE; KB 141; KB 2115; LIOTHYRONINE; MB 07344; PLACEBO; QRX 43; SIMVASTATIN; SOBETIROME; THYROID HORMONE DERIVATIVE; THYROID HORMONE RECEPTOR; TITRACOL; UNCLASSIFIED DRUG;

EID: 77957577068     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (47)
  • 1
    • 64049099095 scopus 로고    scopus 로고
    • Thyroid hormone mimetics: Potential applications in atherosclerosis, obesity and type 2 diabetes
    • Baxter JD, Webb P: Thyroid hormone mimetics: Potential applications in atherosclerosis, obesity and type 2 diabetes. Nat Rev Drug Discov (2009) 8(4):308-320.
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.4 , pp. 308-320
    • Baxter, J.D.1    Webb, P.2
  • 2
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C, Kirby A, Sourjina T, Peto R, Collins R, Simes R: Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet (2005) 366(9493):1267-1278.
    • (2005) Lancet , vol.366 , Issue.9493 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3    Blackwell, L.4    Buck, G.5    Pollicino, C.6    Kirby, A.7    Sourjina, T.8    Peto, R.9    Collins, R.10    Simes, R.11
  • 3
    • 38049033935 scopus 로고    scopus 로고
    • Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis
    • Cholesterol Treatment Trialists' (CTT) Collaborators
    • Cholesterol Treatment Trialists' (CTT) Collaborators; Kearney PM, Blackwell L, Collins R, Keech A, Simes J, Peto R, Armitage J, Baigent C: Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis. Lancet (2008) 371(9607):117-125.
    • (2008) Lancet , vol.371 , Issue.9607 , pp. 117-125
    • Kearney, P.M.1    Blackwell, L.2    Collins, R.3    Keech, A.4    Simes, J.5    Peto, R.6    Armitage, J.7    Baigent, C.8
  • 5
    • 0037143688 scopus 로고    scopus 로고
    • ACC/AHA/NHLBI clinical advisory on the use and safety of statins
    • DOI 10.1161/01.CIR.0000032466.44170.44
    • Pasternak RC, Smith SC Jr, Bairey-Merz CN, Grundy SM, Cleeman JI, Lenfant C; American College of Cardiology; American Heart Association, National Heart, Lung and Blood Institute: ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins. Circulation (2002) 106(8):1024-1028. (Pubitemid 34925341)
    • (2002) Circulation , vol.106 , Issue.8 , pp. 1024-1028
    • Pasternak, R.C.1    Smith Jr., S.C.2    Bairey-Merz, C.N.3    Grundy, S.M.4    Cleeman, J.I.5    Lenfant, C.6
  • 6
    • 0034964207 scopus 로고    scopus 로고
    • Physiological and molecular basis of thyroid hormone action
    • Yen PM: Physiological and molecular basis of thyroid hormone action. Physiol Rev (2001) 81(3):1097-1142.
    • (2001) Physiol Rev , vol.81 , Issue.3 , pp. 1097-1142
    • Yen, P.M.1
  • 7
    • 77953639982 scopus 로고    scopus 로고
    • Molecular aspects of thyroid hormone actions
    • Cheng SY, Leonard JL, Davis PJ: Molecular aspects of thyroid hormone actions. Endocr Rev (2010) 31(2):139-170.
    • (2010) Endocr Rev , vol.31 , Issue.2 , pp. 139-170
    • Cheng, S.Y.1    Leonard, J.L.2    Davis, P.J.3
  • 8
    • 58949094415 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management
    • Vuppalanchi R, Chalasani N: Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management. Hepatology (2009) 49(1):306-317.
    • (2009) Hepatology , vol.49 , Issue.1 , pp. 306-317
    • Vuppalanchi, R.1    Chalasani, N.2
  • 9
    • 84942483136 scopus 로고
    • Dintrophenol and desiccated thyroid in the treatment of obesity
    • Simpkins S: Dintrophenol and desiccated thyroid in the treatment of obesity. J Am Med Assoc (1937) 108:2110-2119.
    • (1937) J Am Med Assoc , vol.108 , pp. 2110-2119
    • Simpkins, S.1
  • 10
    • 0017330636 scopus 로고
    • The coronary drug project - Findings with regard to estrogen, dextrothyroxine, clofibrate and niacin
    • Stamler J: The Coronary Drug Project - Findings with regard to estrogen, dextrothyroxine, clofibrate and niacin. Adv Exp Med Biol (1977) 82:52-75.
    • (1977) Adv Exp Med Biol , vol.82 , pp. 52-75
    • Stamler, J.1
  • 11
    • 9744257146 scopus 로고
    • The metabolic effects of the acetic and propionic acid analogs of thyroxine and triiodothyronine
    • Hill SR Jr, Barker SB, McNeil JH, Tingley JO, Hibbett LL: The metabolic effects of the acetic and propionic acid analogs of thyroxine and triiodothyronine. J Clin Invest (1960) 39(3):523-533.
    • (1960) J Clin Invest , vol.39 , Issue.3 , pp. 523-533
    • Hill Jr., S.R.1    Barker, S.B.2    McNeil, J.H.3    Tingley, J.O.4    Hibbett, L.L.5
  • 13
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass CK, Rosenfeld MG: The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev (2000) 14(2):121-141.
    • (2000) Genes Dev , vol.14 , Issue.2 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 16
    • 33749431724 scopus 로고    scopus 로고
    • Deiodinases: Implications of the local control of thyroid hormone action
    • Bianco AC, Kim BW: Deiodinases: Implications of the local control of thyroid hormone action. J Clin Invest (2006) 116(10):2571-2579.
    • (2006) J Clin Invest , vol.116 , Issue.10 , pp. 2571-2579
    • Bianco, A.C.1    Kim, B.W.2
  • 17
    • 0025251742 scopus 로고
    • Effect of thyroid hormone on hepatic cholesterol 7a hydroxylase, LDL receptor, HMG-coa reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats
    • Ness GC, Pendleton LC, Li YC, Chiang JY: Effect of thyroid hormone on hepatic cholesterol 7a hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats. Biochem Biophys Res Commun (1990) 172(3):1150-1156.
    • (1990) Biochem Biophys Res Commun , vol.172 , Issue.3 , pp. 1150-1156
    • Ness, G.C.1    Pendleton, L.C.2    Li, Y.C.3    Chiang, J.Y.4
  • 18
    • 0033650847 scopus 로고    scopus 로고
    • Thyroid hormone receptor β-deficient mice show complete loss of the normal cholesterol 7α-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol
    • Gullberg H, Rudling M, Forrest D, Angelin B, Vennström B: Thyroid hormone receptor β-deficient mice show complete loss of the normal cholesterol 7α-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol. Mol Endocrinol (2000) 14(11):1739-1749.
    • (2000) Mol Endocrinol , vol.14 , Issue.11 , pp. 1739-1749
    • Gullberg, H.1    Rudling, M.2    Forrest, D.3    Angelin, B.4    Vennström, B.5
  • 19
    • 22644432001 scopus 로고    scopus 로고
    • Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice
    • Johansson L, Rudling M, Scanlan TS, Lundåsen T, Webb P, Baxter J, Angelin B, Parini P: Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice. Proc Natl Acad Sci USA (2005) 102(29):10297-10302.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.29 , pp. 10297-10302
    • Johansson, L.1    Rudling, M.2    Scanlan, T.S.3    Lundåsen, T.4    Webb, P.5    Baxter, J.6    Angelin, B.7    Parini, P.8
  • 20
    • 33747591214 scopus 로고    scopus 로고
    • Mouse sterol response element binding protein-1c gene expression is negatively regulated by thyroid hormone
    • Hashimoto K, Yamada M, Matsumoto S, Monden T, Satoh T, Mori M: Mouse sterol response element binding protein-1c gene expression is negatively regulated by thyroid hormone. Endocrinology (2006) 147(9):4292-4302.
    • (2006) Endocrinology , vol.147 , Issue.9 , pp. 4292-4302
    • Hashimoto, K.1    Yamada, M.2    Matsumoto, S.3    Monden, T.4    Satoh, T.5    Mori, M.6
  • 21
    • 0034611678 scopus 로고    scopus 로고
    • Towards a molecular understanding of adaptive thermogenesis
    • Lowell BB, Spiegelman BM: Towards a molecular understanding of adaptive thermogenesis. Nature (2000) 404(6778):652-660.
    • (2000) Nature , vol.404 , Issue.6778 , pp. 652-660
    • Lowell, B.B.1    Spiegelman, B.M.2
  • 22
    • 0015386126 scopus 로고
    • Plasma triglyceride metabolism in thyroid disease
    • Nikkilä EA, Kekki M: Plasma triglyceride metabolism in thyroid disease. J Clin Invest (1972) 51(8):2103-2114.
    • (1972) J Clin Invest , vol.51 , Issue.8 , pp. 2103-2114
    • Nikkilä, E.A.1    Kekki, M.2
  • 24
    • 0033950142 scopus 로고    scopus 로고
    • Functions of thyroid hormone receptors in mice
    • Forrest D, Vennström B: Functions of thyroid hormone receptors in mice. Thyroid (2000) 10(1):41-52.
    • (2000) Thyroid , vol.10 , Issue.1 , pp. 41-52
    • Forrest, D.1    Vennström, B.2
  • 25
    • 77953233697 scopus 로고    scopus 로고
    • Sobetirome: A case history of bench-to-clinic drug discovery and development
    • Scanlan TS: Sobetirome: A case history of bench-to-clinic drug discovery and development. Heart Fail Rev (2010) 15(2): 177-182.
    • (2010) Heart Fail Rev , vol.15 , Issue.2 , pp. 177-182
    • Scanlan, T.S.1
  • 32
    • 1642505721 scopus 로고    scopus 로고
    • Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: Selective actions relative to 3,5,3'-triiodo-L-thyronine
    • Grover GJ, Egan DM, Sleph PG, Beehler BC, Chiellini G, Nguyen NH, Baxter JD, Scanlan TS: Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: Selective actions relative to 3,5,3'-triiodo-L-thyronine. Endocrinology (2004) 145(4): 1656-1661.
    • (2004) Endocrinology , vol.145 , Issue.4 , pp. 1656-1661
    • Grover, G.J.1    Egan, D.M.2    Sleph, P.G.3    Beehler, B.C.4    Chiellini, G.5    Nguyen, N.H.6    Baxter, J.D.7    Scanlan, T.S.8
  • 35
    • 65449134288 scopus 로고    scopus 로고
    • Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype
    • Perra A, Kowalik MA, Pibiri M, Ledda-Columbano GM, Columbano A: Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype. Hepatology (2009) 49(4):1287-1296.
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1287-1296
    • Perra, A.1    Kowalik, M.A.2    Pibiri, M.3    Ledda-Columbano, G.M.4    Columbano, A.5
  • 37
    • 61949147670 scopus 로고    scopus 로고
    • Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist
    • Cable EE, Finn PD, Stebbins JW, Hou J, Ito BR, van Poelje PD, Linemeyer DL, Erion MD: Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist. Hepatology (2009) 49(2):407-417.
    • (2009) Hepatology , vol.49 , Issue.2 , pp. 407-417
    • Cable, E.E.1    Finn, P.D.2    Stebbins, J.W.3    Hou, J.4    Ito, B.R.5    Van Poelje, P.D.6    Linemeyer, D.L.7    Erion, M.D.8
  • 38
    • 77957606439 scopus 로고    scopus 로고
    • Quatrx Pharmaceuticals, Ann Arbor, Michigan, MI, USA
    • Clinical portfolio - Soberitome: Quatrx Pharmaceuticals, Ann Arbor, Michigan, MI, USA (2008). www.quatrx.com/clinical/431.htm
    • (2008) Clinical Portfolio - Soberitome
  • 40
    • 1042286477 scopus 로고    scopus 로고
    • Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: Effects on lipid homeostasis, inflammation, and atherosclerosis
    • Ricote M, Valledor AF, Glass CK: Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: Effects on lipid homeostasis, inflammation, and atherosclerosis. Arterioscler Thromb Vasc Biol (2004) 24(2):230-239.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , Issue.2 , pp. 230-239
    • Ricote, M.1    Valledor, A.F.2    Glass, C.K.3
  • 41
    • 0842269844 scopus 로고    scopus 로고
    • Regulation of the human cholesterol 7α-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice
    • Drover VA, Agellon LB: Regulation of the human cholesterol 7α-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice. Endocrinology (2004) 145(2):574-581.
    • (2004) Endocrinology , vol.145 , Issue.2 , pp. 574-581
    • Drover, V.A.1    Agellon, L.B.2
  • 42
    • 0036137808 scopus 로고    scopus 로고
    • A distinct thyroid hormone response element mediates repression of the human cholesterol 7α-hydroxylase (CYP7A1) gene promoter
    • Drover VA, Wong NC, Agellon LB: A distinct thyroid hormone response element mediates repression of the human cholesterol 7α-hydroxylase (CYP7A1) gene promoter. Mol Endocrinol (2002) 16(1):14-23.
    • (2002) Mol Endocrinol , vol.16 , Issue.1 , pp. 14-23
    • Drover, V.A.1    Wong, N.C.2    Agellon, L.B.3
  • 43
    • 41549144021 scopus 로고    scopus 로고
    • Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone
    • Gälman C, Bonde Y, Matasconi M, Angelin B, Rudling M: Dramatically increased intestinal absorption of cholesterol following hypophysectomy is normalized by thyroid hormone. Gastroenterology (2008) 134(4):1127-1136.
    • (2008) Gastroenterology , vol.134 , Issue.4 , pp. 1127-1136
    • Gälman, C.1    Bonde, Y.2    Matasconi, M.3    Angelin, B.4    Rudling, M.5
  • 44
    • 77957561470 scopus 로고    scopus 로고
    • Karo Bio AB. Novum, Huddinge, Sweden
    • Research & Development - Eprotirome: Karo Bio AB. Novum, Huddinge, Sweden (2009). www.karobio.com/en/Research-Development/Our-RD-Portfolio2/KB2115/
    • (2009) Research & Development - Eprotirome
  • 45
    • 77953699732 scopus 로고    scopus 로고
    • NPC1L1 and cholesterol transport
    • Betters JL, Yu L: NPC1L1 and cholesterol transport. FEBS Lett (2010) 584(13):2740-7274.
    • (2010) FEBS Lett , vol.584 , Issue.13 , pp. 2740-7274
    • Betters, J.L.1    Yu, L.2
  • 46
    • 2342570322 scopus 로고    scopus 로고
    • Primary hypercholesterolemia: Genetic causes and treatment of five monogenic disorders
    • Pullinger CR, Kane JP, Malloy MJ: Primary hypercholesterolemia: Genetic causes and treatment of five monogenic disorders. Expert Rev Cardiovasc Ther (2003) 1(1):107-119.
    • (2003) Expert Rev Cardiovasc Ther , vol.1 , Issue.1 , pp. 107-119
    • Pullinger, C.R.1    Kane, J.P.2    Malloy, M.J.3
  • 47
    • 34548433987 scopus 로고    scopus 로고
    • Clinical practice. Hypertriglyceridemia
    • Brunzell JD: Clinical practice. Hypertriglyceridemia. N Engl J Med (2007) 357(10):1009-1017.
    • (2007) N Engl J Med , vol.357 , Issue.10 , pp. 1009-1017
    • Brunzell, J.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.