Functional consequences of adenovirus-mediated murine pancreatic gene transfer

Human Gene Therapy

Volumn 8, Issue 6, 1997, Pages 739-746

  McClane, Steven J ^a   Hamilton, Thomas E ^a   Burke, Charlotte V ^a   Raper, Steven E ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; BETA GALACTOSIDE; PSORALEN;

ADENOVIRUS; ANIMAL EXPERIMENT; ARTICLE; CELL DESTRUCTION; CLONING VECTOR; CYSTIC FIBROSIS; DIABETES MELLITUS; EDEMA; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE EXPRESSION; GENE TRANSFER; HUMAN CELL; INFLAMMATION; MOUSE; NONHUMAN; PANCREAS CELL; PANCREAS DISEASE; PANCREATITIS; TISSUE INJURY; TRANSGENE;

EID: 0030983596     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.6-739     Document Type: Article

References (27)

1. ADESANYA, M.R., REDMAN, R.S., BAUM, B.J., and O'CONNELL, B. (1996). Immediate inflammatory responses to adenovirus-mediated gene transfer in rat salivary glands. Hum. Gene Ther. 7, 1085-1093.
2. ADLER, G., HUPP, T., and KERN, H.F. (1982). Alteration of membrane fusion as a cause of acute pancreatitis in the rat. Dig. Dis. Sci. 27, 993-1002.
3. COTTEN, M., WAGNER, E., ZATLOUKAL, K., PHILLIPS, S., CURIEL, D.T., and BIRNSTIEL, M.L. (1992). High-efficiency receptor-mediated delivery of small and large (48 kilobase) gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. Proc. Natl. Acad. Sci. USA 89, 6094-6098.
4. ENGELHARDT, J.F., LITZKY, L., and WILSON, J.M. (1994a). Prolonged transgene expression in cotton rat lung with recombinant adenoviruses defective in E2a. Hum. Gene Ther. 5, 1217-1229.
5. ENGELHARDT, J.F., YE, X., DORANZ, B., and WILSON, J.M. (1994b). Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc. Natl. Acad. Sci. USA 91, 6196-6200.
6. HANSON, C.V. (1992). Photochemical inactivation of viruses with psoralens: An overview. Blood Cells 18, 7-25.
7. JAFFE, H.A., DANEL, C., LONGNECKER, G., METZGER, M., SETOGUCHI, Y., ROSENFELD, M.A., GANT, T.W., THORGEIRSSON, S.S., STRATFORD-PERRICAUDET, L.D., PERRICAUDET, M., PAVIRANI, A., LECOCQ, J.P., and CRYSTAL, R.G. (1992). Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nature Genet. 1, 372-378.
8. KOZARSKY, K., GROSSMAN, M., and WILSON, J.M. (1993). Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia. Somat. Cell Mol. Genet. 19, 449-458.
9. KUCHARCZUK, J.C., RAPER, S.E., ELSHAMI, A.A., AMIN, K.M., STERMAN, D.H., WHEELDON, E.B., WILSON, J.M., LITZSKY, L.A., KAISER, L.R., and ALBELDA, S.M. (1996). Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in non-human primates. Hum. Gene Ther. 7, 2225-2233.
10. LE GAL LA SALLE, G., ROBERT, J.J., BERNARD, S., RIDOUX, V., STRATFORD-PERRICAUDET, L.D., PERRICAUDET, M., and MALLET, J. (1993). An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259, 988-990.
11. LEVITT, M.D., and ECKFELDT, J.H. (1993). Diagnosis of acute pancreatitis. In The Pancreas Biology, Pathobiology, and Disease. V. Liang, W. Go, E. Dimagno, J.D. Gardner, E. Lebenthal, H.A. Reber, and G.A. Scheele, eds (Raven Press, New York) pp. 613-636.
12. MCCLANE, S., HAMILTON, T.E., DEMATTEO, R.P., BURKE, C.V., and RAPER, S.E. (1997). The effect of adenoviral early genes and the host immune system on in vivo pancreatic gene transfer in the mouse. Pancreas (in press).
13. MERRIAM, L.T., WILCOCKSON, D., SAMUEL, I., and JOEHL, RJ. (1996). Ligation-induced acute pancreatitis increases pancreatic and circulating trypsinogen activation peptides. J. Surg. Res. 60, 417-421.
14. OHSHIO, G., SALUJA, A., and STEER, M.L. (1991). Effects of short-term pancreatic duct obstruction in rats. Gastroenterology 100, 196-202.
15. RAPER, S.E., and DEMATTEO, R.P. (1996). Adenovirus-mediated in vivo gene transfer and expression in normal rat pancreas. Pancreas 12, 401-410.
16. ROSENFELD, M.A., YOSHIMURA, K., TRAPNELL, B.C., YONEYAMA, K., ROSENTHAL, E.R., DALEMANS, W., FUKAYAMA, M., BARGON, J., STIER, L.E., STRATFORD-PERRICAUDET, L.D., PERRICAUDET, M., GUGGINO, W.B., PAIRANI, A., LECOCQ, J., and CRYSTAL, R.G. (1992). In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell 68, 143-155.
17. SALUJA, A., SAITO, I., SALUJA, M., HOULIHAN, M.J., POWERS, R.E., MELDOLESI, J., and STEER, M. (1985). In vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein. Am. J. Physiol. (Gastrointest. Liver Physiol.) 12, G702-G710.
18. SAMBROOK, J., FRITSCH, E.F., and MANIATIS, T. (1989). Commonly used techniques in molecular cloning. In Molecular Cloning: A Laboratory Manual, 2nd ed. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York) pp E.5-E.7.
19. SAMUEL, I., and JOEHL, R.J. (1996). Bile-pancreatic juice replacement not cholinergic- and cholecystokinin-receptor blockade reverses acinar cell hyperstimulation after bile-pancreatic duct ligation. Am. J. Surg. 171, 207-211.
20. SAMUEL, I., TORIUMI, Y., WILCOCKSON, D.P., TURKELSON, C.M., SOLOMON, T.E., and JOEHL, R.J. (1995). Bile and pancreatic juice replacement ameliorates early ligation-induced acute pancreatitis in rats. Am. J. Surg. 169, 391-399.
21. SCHEELE, G., ADLER, G., and KERN, H. (1987). Exocytosis occurs at the lateral plasma membrane of the pancreatic acinar cell during supramaximal secretagogue stimulation. Gastroenterology 92, 345-353.
22. STRATFORD-PERRICAUDET, L.D., MAKEH, I., PERRICAUDET, M., and BRIAND, P. (1990). Widespread long-term gene transfer to mouse skeletal muscles and heart. J. Clin. Invest. 90, 626-630.
23. TARTAKOFF, A., and JAMIESON, J.E. (1974). Fractionation of guinea pig pancreas. Methods Enzymol. 31, 41-59.
24. YANG, Y., NUNES, F., BERENCSCI, K., FURTH, E., GONCZOL, E., and WILSON, J. (1994). Cellular immunity to viral antigens limits El-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA 91, 4407-4411.
25. YANG, Y., LI, Q., ERTL, H., and WILSON, J. (1995). Cellular and humoral immune responses to viral antigens create barriers to lung directed gene therapy with recombinant adenoviruses. J. Virol. 69, 2004-2015.
26. YEI, S., MITTEREDER, N., TANG, K., O'SULLIVAN, C., and TRAPNELL, B.C. (1994). Adenovirus-mediated gene transfer for cystic fibrosis: quantitative evaluation of repeated in vivo vector administration to the lung. Gene Ther. 1, 192-2000.
27. ZHANG, W-W., ALEMANY, R., WANG, J., KOCH, P.E., ORDONEZ, N.G., and ROTH, J.A. (1995). Safety evaluation of Ad5CMV-p53 in vitro and in vivo. Hum. Gene Ther. 6, 155-164.