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Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 19, 2010, Pages 5732-5734

Design, synthesis and docking studies on phenoxy-3-piperazin-1-yl-propan-2- ol derivatives as protein tyrosine phosphatase 1B inhibitors

(5) Gupta, Swati a Pandey, Gyanendra a Rahuja, Neha a Srivastava, Arvind K a Saxena, Anil K a

a CENTRAL DRUG RESEARCH INSTITUTE (India)

Author keywords

Docking; Protein tyrosine phosphatases 1B

Indexed keywords

1 (4 CHLOROPHENOXY) 3 [4 (4 NITROPHENYL)PIPERAZIN 1 YL]PROPAN 2 OL; 4 [2 HYDROXY 3 (3 METHYL 4 4 TOLYL PIPERAZIN 1 YL) PROPOXY]BENZONITRILE; ANTIDIABETIC AGENT; ARGININE; GLUCOSE; METFORMIN; PIPERAZINE DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; STREPTOZOCIN; SUGAR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); DRUG DESIGN; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; HYDROGEN BOND; IN VITRO STUDY; MOLECULAR DOCKING; MOUSE; NONHUMAN;

ANIMALS; BINDING SITES; CATALYTIC DOMAIN; COMPUTER SIMULATION; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DRUG DESIGN; ENZYME INHIBITORS; HYPOGLYCEMIC AGENTS; PIPERAZINES; PROPANOLS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RATS;

EID: 77957553514 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.08.008 Document Type: Article

Times cited : (16)

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