메뉴 건너뛰기




Volumn 13, Issue 6, 2004, Pages 967-975

O6-methylguanine-DNA methyltransferase gene: Epigenetic silencing and prognostic value in head and neck squamous cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

DNA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; GUANINE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

EID: 2942620221     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (71)

References (45)
  • 2
    • 0030240944 scopus 로고    scopus 로고
    • How cancer arises
    • Weinberg RA. How cancer arises. Sci Am 1996;275:62-70.
    • (1996) Sci Am , vol.275 , pp. 62-70
    • Weinberg, R.A.1
  • 3
    • 0034188505 scopus 로고    scopus 로고
    • Epidemiology of tobacco carcinogenesis
    • Shields PG. Epidemiology of tobacco carcinogenesis. Curr Oncol Rep 2000;2:257-62.
    • (2000) Curr Oncol Rep , vol.2 , pp. 257-262
    • Shields, P.G.1
  • 5
    • 0021287403 scopus 로고
    • 6 of guanine is only one of many chemical events that may initiate carcinogenesis
    • 6 of guanine is only one of many chemical events that may initiate carcinogenesis. Cancer Invest 1984;2:233-8.
    • (1984) Cancer Invest , vol.2 , pp. 233-238
    • Singer, B.1
  • 7
    • 0021894988 scopus 로고
    • 6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis
    • 6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis. Mutat Res 1985;145:1-16.
    • (1985) Mutat Res , vol.145 , pp. 1-16
    • Yarosh, D.B.1
  • 8
    • 0025195404 scopus 로고
    • 6-alkylguanine-DNA methyltransferase regulation and importance in response to alkylating carcinogenic and therapeutic agents
    • 6-alkylguanine-DNA methyltransferase regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 1990;50:6119-29.
    • (1990) Cancer Res , vol.50 , pp. 6119-6129
    • Pegg, A.E.1
  • 9
    • 0021074016 scopus 로고
    • Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations
    • Sukumar S, Notario V, Martin-Zanca D, Barbacid M. Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations. Nature 1983;306:658-61.
    • (1983) Nature , vol.306 , pp. 658-661
    • Sukumar, S.1    Notario, V.2    Martin-Zanca, D.3    Barbacid, M.4
  • 10
    • 0019947771 scopus 로고
    • Mechanism of activation of a human oncogene
    • Tabin CJ, Bradley SM, Bargmann CI, et al. Mechanism of activation of a human oncogene. Nature 1982;300:143-9.
    • (1982) Nature , vol.300 , pp. 143-149
    • Tabin, C.J.1    Bradley, S.M.2    Bargmann, C.I.3
  • 11
    • 0037227642 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase: Promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors
    • 6-methylguanine-DNA methyltransferase: promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors. Mol Carcinogenesis 2003;36:23-31.
    • (2003) Mol Carcinogenesis , vol.36 , pp. 23-31
    • Yin, D.1    Xie, D.2    Hofmann, W.K.3
  • 12
    • 0035874892 scopus 로고    scopus 로고
    • Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis
    • Esteller M, Risques RA, Toyota M, et al. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis. Cancer Res 2001;61:4689-92.
    • (2001) Cancer Res , vol.61 , pp. 4689-4692
    • Esteller, M.1    Risques, R.A.2    Toyota, M.3
  • 13
    • 0035890742 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer
    • 6-methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer. Cancer Res 2001;61:8113-7.
    • (2001) Cancer Res , vol.61 , pp. 8113-8117
    • Wolf, P.1    Hu, Y.C.2    Doffek, K.3    Sidransky, D.4    Ahrendt, S.A.5
  • 14
    • 0035575781 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma
    • 6-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma. Cancer 2001;92:2760-8.
    • (2001) Cancer , vol.92 , pp. 2760-2768
    • Park, T.J.1    Han, S.U.2    Cho, Y.K.3    Paik, W.K.4    Kim, Y.B.5    Lim, I.K.6
  • 15
    • 19244370208 scopus 로고    scopus 로고
    • 6methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
    • 6methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res 2000;60:2368-71.
    • (2000) Cancer Res , vol.60 , pp. 2368-2371
    • Esteller, M.1    Toyota, M.2    Sanchez-Cespedes, M.3
  • 16
    • 0034095131 scopus 로고    scopus 로고
    • Promoter-region hypermethylation and gene silencing in human cancer
    • PA Jones, Vogt PK, editors. New York: Springer-Verlag
    • Herman JG, Baylin SB. Promoter-region hypermethylation and gene silencing in human cancer. In: PA Jones, Vogt PK, editors. DNA methylation and cancer. New York: Springer-Verlag; 2000. p. 35-50.
    • (2000) DNA Methylation and Cancer , pp. 35-50
    • Herman, J.G.1    Baylin, S.B.2
  • 17
    • 0037461896 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours
    • Honorio S, Agathanggelou A, Wernert N, Rothe M, Maher ER, Latif F. Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours. Oncogene 2003;22:461-6.
    • (2003) Oncogene , vol.22 , pp. 461-466
    • Honorio, S.1    Agathanggelou, A.2    Wernert, N.3    Rothe, M.4    Maher, E.R.5    Latif, F.6
  • 18
    • 0035870280 scopus 로고    scopus 로고
    • Epigenetic patterns in the progression of esophageal adenocarcinoma
    • Eads CA, Lord RV, Wickramasinghe K, et al. Epigenetic patterns in the progression of esophageal adenocarcinoma. Cancer Res 2001;61:3410-8.
    • (2001) Cancer Res , vol.61 , pp. 3410-3418
    • Eads, C.A.1    Lord, R.V.2    Wickramasinghe, K.3
  • 19
    • 0037392737 scopus 로고    scopus 로고
    • Profile of aberrant CpG island methylation along multistep gastric carcinogenesis
    • Kang GH, Lee S, Kim JS, Jung HY. Profile of aberrant CpG island methylation along multistep gastric carcinogenesis. Lab Invest 2003;83:519-26.
    • (2003) Lab Invest , vol.83 , pp. 519-526
    • Kang, G.H.1    Lee, S.2    Kim, J.S.3    Jung, H.Y.4
  • 20
    • 0037463277 scopus 로고    scopus 로고
    • CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection
    • Matsukura S, Soejima H, Nakagawachi T, et al. CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection. Br J Cancer 2003;88:521-9.
    • (2003) Br J Cancer , vol.88 , pp. 521-529
    • Matsukura, S.1    Soejima, H.2    Nakagawachi, T.3
  • 21
    • 0037328351 scopus 로고    scopus 로고
    • Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas
    • House MG, Guo M, Iacobuzio-Donahue C, Herman JG. Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas. Carcinogenesis 2003;24:193-8.
    • (2003) Carcinogenesis , vol.24 , pp. 193-198
    • House, M.G.1    Guo, M.2    Iacobuzio-Donahue, C.3    Herman, J.G.4
  • 22
    • 0036184623 scopus 로고    scopus 로고
    • Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features
    • Maruyama R, Toyooka S, Toyooka KO, et al. Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features. Clin Cancer Res 2002;8:514-9.
    • (2002) Clin Cancer Res , vol.8 , pp. 514-519
    • Maruyama, R.1    Toyooka, S.2    Toyooka, K.O.3
  • 23
    • 0037005988 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma
    • 6-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J Natl Cancer Inst 2002;94:26-32.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 26-32
    • Esteller, M.1    Gaidano, G.2    Goodman, S.N.3
  • 24
    • 0033557903 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
    • 6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res 1999;59:793-7.
    • (1999) Cancer Res , vol.59 , pp. 793-797
    • Esteller, K.1    Hamilton, S.R.2    Burger, P.C.3    Baylin, S.B.4    Herman, J.G.5
  • 25
    • 0034652596 scopus 로고    scopus 로고
    • Gene promoter hypermethylation in tumors and serum of head and neck cancer patients
    • Sanchez-Cespedes M, Esteller M, Wu L, et al. Gene promoter hypermethylation in tumors and serum of head and neck cancer patients. Cancer Res 2000;60:892-5.
    • (2000) Cancer Res , vol.60 , pp. 892-895
    • Sanchez-Cespedes, M.1    Esteller, M.2    Wu, L.3
  • 26
    • 0035116695 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients
    • 6-methylguanine-DNA methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. Cancer Res 2001;61:939-42.
    • (2001) Cancer Res , vol.61 , pp. 939-942
    • Rosas, S.L.B.1    Koch, W.2    Carvalho, M.D.C.3
  • 28
    • 0642378532 scopus 로고    scopus 로고
    • Differential gene methylation in undifferentiated nasopharyngeal carcinoma
    • Wong TS, Tang KC, Kwong DL, et al. Differential gene methylation in undifferentiated nasopharyngeal carcinoma. Int J Oncol 2003;22:869-74.
    • (2003) Int J Oncol , vol.22 , pp. 869-874
    • Wong, T.S.1    Tang, K.C.2    Kwong, D.L.3
  • 29
    • 0345269743 scopus 로고    scopus 로고
    • Promoter hypermethylation profile of tumor-associated genes p16, p15, hMLH1, MGMT and E-cadherin in oral squamous cell carcinoma
    • Viswanathan M, Tsuchida N, Shanmugam G. Promoter hypermethylation profile of tumor-associated genes p16, p15, hMLH1, MGMT and E-cadherin in oral squamous cell carcinoma. Int J Cancer 2003;105:41-6.
    • (2003) Int J Cancer , vol.105 , pp. 41-46
    • Viswanathan, M.1    Tsuchida, N.2    Shanmugam, G.3
  • 30
    • 0037287135 scopus 로고    scopus 로고
    • Promoter hypermethylation and inactivation of hMLH1, a DNA mismatch repair gene, in head and neck squamous cell carcinoma
    • Liu K, Zuo C, Luo QK, Suen JY, Hanna E, Fan CY. Promoter hypermethylation and inactivation of hMLH1, a DNA mismatch repair gene, in head and neck squamous cell carcinoma. Diagn Mol Pathol 2003;12:50-6.
    • (2003) Diagn Mol Pathol , vol.12 , pp. 50-56
    • Liu, K.1    Zuo, C.2    Luo, Q.K.3    Suen, J.Y.4    Hanna, E.5    Fan, C.Y.6
  • 31
    • 0034780112 scopus 로고    scopus 로고
    • Frequent allelic imbalance and loss of protein expression of the DNA repair gene hOGG1 in head and neck squamous cell carcinoma
    • Fan C, Liu KL, Huang HY, et al. Frequent allelic imbalance and loss of protein expression of the DNA repair gene hOGG1 in head and neck squamous cell carcinoma. Lab Invest 2001;81:1429-38.
    • (2001) Lab Invest , vol.81 , pp. 1429-1438
    • Fan, C.1    Liu, K.L.2    Huang, H.Y.3
  • 32
    • 0036560975 scopus 로고    scopus 로고
    • Promoter hypermethylation: An important epigenetic mechanism for hMLH1 gene inactivation in head and neck squamous cell carcinoma
    • Liu KL, Huang HY, Mukunyadzi P, Suen J, Hanna E, Fan CY. Promoter hypermethylation: an important epigenetic mechanism for hMLH1 gene inactivation in head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg 2002;126:548-53.
    • (2002) Otolaryngol Head Neck Surg , vol.126 , pp. 548-553
    • Liu, K.L.1    Huang, H.Y.2    Mukunyadzi, P.3    Suen, J.4    Hanna, E.5    Fan, C.Y.6
  • 34
    • 0028169360 scopus 로고
    • 6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas
    • 6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas. Cancer Res 1994;54:4648-52.
    • (1994) Cancer Res , vol.54 , pp. 4648-4652
    • Liu, L.1    Allay, E.2    Dumenco, L.L.3    Gerson, S.L.4
  • 36
    • 0031427721 scopus 로고    scopus 로고
    • High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase
    • Iwakuma T, Sakumi K, Nakatsuru Y, et al. High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase. Carcinogenesis 1997;18:1631-5.
    • (1997) Carcinogenesis , vol.18 , pp. 1631-1635
    • Iwakuma, T.1    Sakumi, K.2    Nakatsuru, Y.3
  • 37
    • 0035665415 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in hepatocellular, gastric, and breast cancers
    • 6-methylguanine-DNA methyltransferase in hepatocellular, gastric, and breast cancers. Ann Surg Oncol 2001;8:808-16.
    • (2001) Ann Surg Oncol , vol.8 , pp. 808-816
    • Matsukura, S.1    Miyazaki, K.2    Yakushiji, H.3
  • 38
    • 0037987700 scopus 로고    scopus 로고
    • Tumour suppressor gene expression correlates with gastric cancer prognosis
    • Lee HS, Lee HK, Kim HS, Yang HK, Kim WH. Tumour suppressor gene expression correlates with gastric cancer prognosis. J Pathol 2003;200:39-46.
    • (2003) J Pathol , vol.200 , pp. 39-46
    • Lee, H.S.1    Lee, H.K.2    Kim, H.S.3    Yang, H.K.4    Kim, W.H.5
  • 39
    • 0036834864 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyl transferase gene expression and prognosis in breast carcinoma
    • 6-methylguanine-DNA methyl transferase gene expression and prognosis in breast carcinoma. Int J Oncol 2002;21:1125-31.
    • (2002) Int J Oncol , vol.21 , pp. 1125-1131
    • Cayre, A.1    Penault-Llorca, F.2    De Latour, M.3
  • 40
    • 12244297095 scopus 로고    scopus 로고
    • 6-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: Associations with clinical outcome
    • 6-methylguanine DNA methyltransferase methylation analysis in curatively resected non-small cell lung cancer: associations with clinical outcome. Clin Cancer Res 2003;9:223-7.
    • (2003) Clin Cancer Res , vol.9 , pp. 223-227
    • Brabender, J.1    Usadel, H.2    Metzger, R.3
  • 41
    • 0037393981 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase is an independent predictor of shortened progression free survival in patients with low-grade diffuse astrocytomas
    • 6-methylguanine-DNA methyltransferase is an independent predictor of shortened progression free survival in patients with low-grade diffuse astrocytomas. Brain Pathol 2003;13:176-84.
    • (2003) Brain Pathol , vol.13 , pp. 176-184
    • Komine, C.1    Watanabe, T.2    Katayama, Y.3    Yoshino, A.4    Yokoyama, T.5    Fukushima, T.6
  • 42
    • 0036570062 scopus 로고    scopus 로고
    • Clinical relevance of MGMT in the treatment of cancer
    • Gerson SL. Clinical relevance of MGMT in the treatment of cancer. J Clin Oncol 2002;20:2388-99.
    • (2002) J Clin Oncol , vol.20 , pp. 2388-2399
    • Gerson, S.L.1
  • 43
    • 0032574814 scopus 로고    scopus 로고
    • Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes
    • Kawate H, Sakumi K, Tsuzuki T, et al. Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc Natl Acad Sci USA 1998;95:5116-29.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5116-5129
    • Kawate, H.1    Sakumi, K.2    Tsuzuki, T.3
  • 44
    • 0031595389 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: A Southwest Oncology Group study
    • 6-methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group study. J Clin Oncol 1998;16:3310-5.
    • (1998) J Clin Oncol , vol.16 , pp. 3310-3315
    • Jaeckle, K.A.1    Eyre, H.J.2    Townsend, J.J.3
  • 45
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 2000;343:1350-4.
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.