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Volumn 177, Issue 4, 2010, Pages 1765-1778

Tuberin regulates E-cadherin localization: Implications in epithelial-mesenchymal transition

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; OCCLUDIN; PROTEIN KINASE B; RAPAMYCIN; SMOOTH MUSCLE ACTIN; TRANSCRIPTION FACTOR SNAIL; TUBERIN; UVOMORULIN;

EID: 77957329131     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090233     Document Type: Article
Times cited : (53)

References (45)
  • 2
    • 0043127125 scopus 로고    scopus 로고
    • Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
    • Inoki K, Li Y, Xu T, Guan KL: Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev 2003, 17:1829-1834
    • (2003) Genes Dev , vol.17 , pp. 1829-1834
    • Inoki, K.1    Li, Y.2    Xu, T.3    Guan, K.L.4
  • 3
    • 11244297916 scopus 로고    scopus 로고
    • Dysregulation of the TSC-mTOR pathway in human disease
    • Inoki K, Corradetti MN, Guan KL: Dysregulation of the TSC-mTOR pathway in human disease. Nat Genet 2005, 37:19-24
    • (2005) Nat Genet , vol.37 , pp. 19-24
    • Inoki, K.1    Corradetti, M.N.2    Guan, K.L.3
  • 8
    • 1642345487 scopus 로고    scopus 로고
    • The LAM cell: What is it, where does it come from, and why does it grow?
    • Finlay G: The LAM cell: what is it, where does it come from, and why does it grow? Am J Physiol Lung Cell Mol Physiol 2004, 286:L690-L693
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286
    • Finlay, G.1
  • 9
    • 0042261552 scopus 로고    scopus 로고
    • Neoplasms with perivascular epitheloid cell differentiation (PEComas)
    • World Health Organization Classification of Tumors. Edited by CDM Fletcher, KK Unni, F Mertens. Lyon, France, IARC Press
    • Folpe AL: Neoplasms with perivascular epitheloid cell differentiation (PEComas). World Health Organization Classification of Tumors. Pathology & Genetics: Tumors of Soft Tissue and Bone. Edited by CDM Fletcher, KK Unni, F Mertens. Lyon, France, IARC Press, 2002, pp. 221-222
    • (2002) Pathology & Genetics: Tumors of Soft Tissue and Bone , pp. 221-222
    • Folpe, A.L.1
  • 10
    • 0344155279 scopus 로고    scopus 로고
    • Metastasis of benign tumor cells in tuberous sclerosis complex
    • Henske EP: Metastasis of benign tumor cells in tuberous sclerosis complex. Genes Chromosomes Cancer 2003, 38:376-381
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 376-381
    • Henske, E.P.1
  • 14
    • 0037255952 scopus 로고    scopus 로고
    • Recurrence of lymphangioleiomyomatosis after single lung transplantation: New insights into pathogenesis
    • Bittmann I, Rolf B, Amann G, Lohrs U: Recurrence of lymphangioleiomyomatosis after single lung transplantation: new insights into pathogenesis. Hum Pathol 2003, 34:95-98
    • (2003) Hum Pathol , vol.34 , pp. 95-98
    • Bittmann, I.1    Rolf, B.2    Amann, G.3    Lohrs, U.4
  • 16
    • 37849033529 scopus 로고    scopus 로고
    • Smooth muscle like cells in pulmonary lymphangioleiomyomatosis
    • Krymskaya VP: Smooth muscle like cells in pulmonary lymphangioleiomyomatosis. Proc Am Thorac Soc 2008, 5:119-126
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 119-126
    • Krymskaya, V.P.1
  • 17
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: New insights in signaling, development, and disease
    • Lee JM, Dedhar S, Kalluri R, Thompson EW: The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 2006, 172:973-981
    • (2006) J Cell Biol , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 20
    • 0029814436 scopus 로고    scopus 로고
    • Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region
    • Jin F, Wienecke R, Xiao GH, Maize JC Jr, DeClue JE, Yeung RS: Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region. Proc Natl Acad Sci USA 1996, 93:9154-9159
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9154-9159
    • Jin, F.1    Wienecke, R.2    Xiao, G.H.3    Maize Jr., J.C.4    DeClue, J.E.5    Yeung, R.S.6
  • 21
    • 33744919546 scopus 로고    scopus 로고
    • Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway
    • Jiang X, Yeung RS: Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway. Cancer Res 2006, 66:5258-5269
    • (2006) Cancer Res , vol.66 , pp. 5258-5269
    • Jiang, X.1    Yeung, R.S.2
  • 23
    • 1542299041 scopus 로고    scopus 로고
    • Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin
    • Wendeler MW, Praus M, Jung R, Hecking M, Metzig C, Gessner R: Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin. Exp Cell Res 2004, 294:345-355
    • (2004) Exp Cell Res , vol.294 , pp. 345-355
    • Wendeler, M.W.1    Praus, M.2    Jung, R.3    Hecking, M.4    Metzig, C.5    Gessner, R.6
  • 25
    • 1842861671 scopus 로고    scopus 로고
    • Tuberin is a component of lipid rafts and mediates caveolin-1 localization: Role of TSC2 in post-Golgi transport
    • Jones KA, Jiang X, Yamamoto Y, Yeung RS: Tuberin is a component of lipid rafts and mediates caveolin-1 localization: role of TSC2 in post-Golgi transport. Exp Cell Res 2004, 295:512-524
    • (2004) Exp Cell Res , vol.295 , pp. 512-524
    • Jones, K.A.1    Jiang, X.2    Yamamoto, Y.3    Yeung, R.S.4
  • 26
    • 44849114657 scopus 로고    scopus 로고
    • The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake
    • Jiang X, Kenerson H, Aicher L, Miyaoka R, Eary J, Bissler J, Yeung RS: The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake. Am J Pathol 2008, 172:1748-1756
    • (2008) Am J Pathol , vol.172 , pp. 1748-1756
    • Jiang, X.1    Kenerson, H.2    Aicher, L.3    Miyaoka, R.4    Eary, J.5    Bissler, J.6    Yeung, R.S.7
  • 27
    • 0345736990 scopus 로고    scopus 로고
    • Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
    • Lu Z, Ghosh S, Wang Z, Hunter T: Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion. Cancer Cell 2003, 4:499-515
    • (2003) Cancer Cell , vol.4 , pp. 499-515
    • Lu, Z.1    Ghosh, S.2    Wang, Z.3    Hunter, T.4
  • 28
    • 33947538050 scopus 로고    scopus 로고
    • Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism
    • Wan X, Harkavy B, Shen N, Grohar P, Helman LJ: Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism. Oncogene 2007, 26:1932-1940
    • (2007) Oncogene , vol.26 , pp. 1932-1940
    • Wan, X.1    Harkavy, B.2    Shen, N.3    Grohar, P.4    Helman, L.J.5
  • 30
    • 8644274532 scopus 로고    scopus 로고
    • The tuberous sclerosis complex genes in tumor development
    • Mak BC, Yeung RS: The tuberous sclerosis complex genes in tumor development. Cancer Invest 2004, 22:588-603
    • (2004) Cancer Invest , vol.22 , pp. 588-603
    • Mak, B.C.1    Yeung, R.S.2
  • 32
    • 0037458733 scopus 로고    scopus 로고
    • The tuberin-hamartin complex negatively regulates β-catenin signaling activity
    • Mak BC, Takemaru K, Kenerson HL, Moon RT, Yeung RS: The tuberin-hamartin complex negatively regulates β-catenin signaling activity. J Biol Chem 2003, 278:5947-5951
    • (2003) J Biol Chem , vol.278 , pp. 5947-5951
    • Mak, B.C.1    Takemaru, K.2    Kenerson, H.L.3    Moon, R.T.4    Yeung, R.S.5
  • 34
    • 77957377778 scopus 로고    scopus 로고
    • The loss of tuberin promotes cell invasion through the β-catenin pathway
    • DOI: 10.1165/rcmb.2008-0335OC
    • Barnes EA, Kenerson HL, Mak BC, Yeung RS. The loss of tuberin promotes cell invasion through the β-catenin pathway. Am J Respir Cell Mol Biol 2009, DOI: 10.1165/rcmb.2008-0335OC
    • (2009) Am J Respir Cell Mol Biol
    • Barnes, E.A.1    Kenerson, H.L.2    Mak, B.C.3    Yeung, R.S.4
  • 38
    • 41549162752 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states in development and disease
    • Baum B, Settleman J, Quinlan MP: Transitions between epithelial and mesenchymal states in development and disease. Semin Cell Dev Biol 2008, 19:294-308
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 294-308
    • Baum, B.1    Settleman, J.2    Quinlan, M.P.3
  • 39
    • 16844368863 scopus 로고    scopus 로고
    • Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
    • Elloul S, Elstrand MB, Nesland JM, Trope CG, Kvalheim G, Goldberg I, Reich R, Davidson B: Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer 2005, 103:1631-1643
    • (2005) Cancer , vol.103 , pp. 1631-1643
    • Elloul, S.1    Elstrand, M.B.2    Nesland, J.M.3    Trope, C.G.4    Kvalheim, G.5    Goldberg, I.6    Reich, R.7    Davidson, B.8
  • 40
    • 33745086313 scopus 로고    scopus 로고
    • Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
    • Shioiri M, Shida T, Koda K, Oda K, Seike K, Nishimura M, Takano S, Miyazaki M: Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients. Br J Cancer 2006, 94:1816-1822
    • (2006) Br J Cancer , vol.94 , pp. 1816-1822
    • Shioiri, M.1    Shida, T.2    Koda, K.3    Oda, K.4    Seike, K.5    Nishimura, M.6    Takano, S.7    Miyazaki, M.8
  • 44
    • 33750433893 scopus 로고    scopus 로고
    • Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis
    • Neef M, Ledermann M, Saegesser H, Schneider V, Reichen J: Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis. J Hepatol 2006, 45:786-796
    • (2006) J Hepatol , vol.45 , pp. 786-796
    • Neef, M.1    Ledermann, M.2    Saegesser, H.3    Schneider, V.4    Reichen, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.