메뉴 건너뛰기




Volumn 5, Issue 5, 2010, Pages 763-775

Cardiac regeneration using human embryonic stem cells: Producing cells for future therapy

Author keywords

cardiac regeneration; cardiomyocyte; human embryonic stem cell; myocardial repair

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CD133 ANTIGEN; CD135 ANTIGEN; STEM CELL FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; VASCULOTROPIN;

EID: 77957320317     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.10.52     Document Type: Review
Times cited : (46)

References (76)
  • 1
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2009 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D, Adams R, Carnethon M et al.: Heart disease and stroke statistics - 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 119(3), 480-486 (2009).
    • (2009) Circulation , vol.119 , Issue.3 , pp. 480-486
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3
  • 2
    • 57349194198 scopus 로고    scopus 로고
    • Cardiogenesis and the complex biology of regenerative cardiovascular medicine
    • Chien KR, Domian IJ, Parker KK: Cardiogenesis and the complex biology of regenerative cardiovascular medicine. Science 322(5907), 1494-1497 (2008).
    • (2008) Science , vol.322 , Issue.5907 , pp. 1494-1497
    • Chien, K.R.1    Domian, I.J.2    Parker, K.K.3
  • 3
    • 0034904645 scopus 로고    scopus 로고
    • Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
    • ••First comprehensive characterization of human embryonic stem cell hESC-derived cardiomyocytes CMs
    • Kehat I, Kenyagin-Karsenti D, Snir M et al.: Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J. Clin. Invest. 108(3), 407-414 (2001). ••First comprehensive characterization of human embryonic stem cell (hESC)-derived cardiomyocytes (CMs).
    • (2001) J. Clin. Invest. , vol.108 , Issue.3 , pp. 407-414
    • Kehat, I.1    Kenyagin-Karsenti, D.2    Snir, M.3
  • 4
    • 0037144701 scopus 로고    scopus 로고
    • Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu C, Police S, Rao N, Carpenter MK: Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ. Res. 91(6), 501-508 (2002).
    • (2002) Circ. Res. , vol.91 , Issue.6 , pp. 501-508
    • Xu, C.1    Police, S.2    Rao, N.3    Carpenter, M.K.4
  • 5
    • 0034136393 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
    • Itskovitz-Eldor J, Schuldiner M, Karsenti D et al.: Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol. Med. 6(2), 88-95 (2000).
    • (2000) Mol. Med. , vol.6 , Issue.2 , pp. 88-95
    • Itskovitz-Eldor, J.1    Schuldiner, M.2    Karsenti, D.3
  • 6
    • 0038300672 scopus 로고    scopus 로고
    • Human embryonic stem cells develop into multiple types of cardiac myocytes: Action potential characterization
    • ••First characterization of electrophysiological heterogeneity among cultures of hESC-derived CMs
    • He JQ, Ma Y, Lee Y, Thomson JA, Kamp TJ: Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ. Res. 93(1), 32-39 (2003). ••First characterization of electrophysiological heterogeneity among cultures of hESC-derived CMs.
    • (2003) Circ. Res. , vol.93 , Issue.1 , pp. 32-39
    • He, J.Q.1    Ma, Y.2    Lee, Y.3    Thomson, J.A.4    Kamp, T.J.5
  • 7
    • 0028154103 scopus 로고
    • Structural basis of end-stage failure in ischemic cardiomyopathy in humans
    • Beltrami CA, Finato N, Rocco M et al.: Structural basis of end-stage failure in ischemic cardiomyopathy in humans. Circulation 89(1), 151-163 (1994).
    • (1994) Circulation , vol.89 , Issue.1 , pp. 151-163
    • Beltrami, C.A.1    Finato, N.2    Rocco, M.3
  • 8
    • 0034856553 scopus 로고    scopus 로고
    • Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering
    • Fukuda K: Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering. Artif. Organs 25(3), 187-193 (2001).
    • (2001) Artif. Organs , vol.25 , Issue.3 , pp. 187-193
    • Fukuda, K.1
  • 9
    • 42149094990 scopus 로고    scopus 로고
    • Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK
    • Graichen R, Xu X, Braam SR et al.: Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK. Differentiation 76(4), 357-370 (2008).
    • (2008) Differentiation , vol.76 , Issue.4 , pp. 357-370
    • Graichen, R.1    Xu, X.2    Braam, S.R.3
  • 10
    • 77957294191 scopus 로고    scopus 로고
    • Timed inhibition of p38MAPK directs accelerated differentiation of human embryonic stem cells into cardiomyocytes
    • Epub ahead of print
    • Gaur M, Ritner C, Sievers RE et al.: Timed inhibition of p38MAPK directs accelerated differentiation of human embryonic stem cells into cardiomyocytes. Cytotherapy (2010) (Epub ahead of print).
    • (2010) Cytotherapy
    • Gaur, M.1    Ritner, C.2    Sievers, R.E.3
  • 11
    • 0026021502 scopus 로고
    • Visceralendoderm-like cell lines induce differentiation of murine P19 embryonal carcinoma cells
    • Mummery CL, van Achterberg TA, van den Eijnden-van Raaij AJ et al.: Visceralendoderm-like cell lines induce differentiation of murine P19 embryonal carcinoma cells. Differentiation 46(1), 51-60 (1991).
    • (1991) Differentiation , vol.46 , Issue.1 , pp. 51-60
    • Mummery, C.L.1    Van Achterberg, T.A.2    Van Den Eijnden-Van Raaij, A.J.3
  • 12
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells
    • Mummery C, Ward-van Oostwaard D, Doevendans P et al.: Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 107(21), 2733-2740 (2003).
    • (2003) Circulation , vol.107 , Issue.21 , pp. 2733-2740
    • Mummery, C.1    Oostwaard, D.W.-V.2    Doevendans, P.3
  • 13
    • 54249098708 scopus 로고    scopus 로고
    • Chemically defned medium supporting cardiomyocyte differentiation of human embryonic stem cells
    • Xu XQ, Graichen R, Soo SY et al.: Chemically defned medium supporting cardiomyocyte differentiation of human embryonic stem cells. Differentiation 76(9), 958-970 (2008).
    • (2008) Differentiation , vol.76 , Issue.9 , pp. 958-970
    • Xu, X.Q.1    Graichen, R.2    Soo, S.Y.3
  • 14
    • 0022529105 scopus 로고
    • Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors
    • Mummery CL, Feijen A, Moolenaar WH, van den Brink CE, de Laat SW: Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors. Exp. Cell Res. 165(1), 229-242 (1986).
    • (1986) Exp. Cell. Res. , vol.165 , Issue.1 , pp. 229-242
    • Mummery, C.L.1    Feijen, A.2    Moolenaar, W.H.3    Van Den Brink, C.E.4    De Laat, S.W.5
  • 15
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Lafamme MA, Chen KY, Naumova AV et al.: Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat. Biotechnol. 25(9), 1015-1024 (2007).
    • (2007) Nat. Biotechnol. , vol.25 , Issue.9 , pp. 1015-1024
    • Lafamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3
  • 16
    • 0028905441 scopus 로고
    • Activin-A and FGF-2 mimic the inductive effects of anterior endoderm on terminal cardiac myogenesis in vitro
    • Sugi Y, Lough J: Activin-A and FGF-2 mimic the inductive effects of anterior endoderm on terminal cardiac myogenesis in vitro. Dev. Biol. 168(2), 567-574 (1995).
    • (1995) Dev. Biol. , vol.168 , Issue.2 , pp. 567-574
    • Sugi, Y.1    Lough, J.2
  • 17
    • 0025324104 scopus 로고
    • Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A
    • Smith JC, Price BM, Van Nimmen K, Huylebroeck D: Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A. Nature 345(6277), 729-731 (1990).
    • (1990) Nature , vol.345 , Issue.6277 , pp. 729-731
    • Smith, J.C.1    Price, B.M.2    Van Nimmen, K.3    Huylebroeck, D.4
  • 18
    • 0037093110 scopus 로고    scopus 로고
    • Significance of bone morphogenetic protein-4 function in the initial myofibrillogenesis of chick cardiogenesis
    • Nakajima Y, Yamagishi T, Ando K, Nakamura H: Significance of bone morphogenetic protein-4 function in the initial myofibrillogenesis of chick cardiogenesis. Dev. Biol. 245(2), 291-303 (2002).
    • (2002) Dev. Biol. , vol.245 , Issue.2 , pp. 291-303
    • Nakajima, Y.1    Yamagishi, T.2    Ando, K.3    Nakamura, H.4
  • 19
    • 0030601359 scopus 로고    scopus 로고
    • Combined BMP-2 and FGF-4, but neither factor alone, induces cardiogenesis in non-precardiac embryonic mesoderm
    • Lough J, Barron M, Brogley M, Sugi Y, Bolender DL, Zhu X: Combined BMP-2 and FGF-4, but neither factor alone, induces cardiogenesis in non-precardiac embryonic mesoderm. Dev. Biol. 178(1), 198-202 (1996).
    • (1996) Dev. Biol. , vol.178 , Issue.1 , pp. 198-202
    • Lough, J.1    Barron, M.2    Brogley, M.3    Sugi, Y.4    Bolender, D.L.5    Zhu, X.6
  • 20
    • 0032535223 scopus 로고    scopus 로고
    • Regulation of avian cardiac myogenesis by activin/TGF-β and bone morphogenetic proteins
    • Ladd AN, Yatskievych TA, Antin PB: Regulation of avian cardiac myogenesis by activin/TGF-β and bone morphogenetic proteins. Dev. Biol. 204(2), 407-419 (1998).
    • (1998) Dev. Biol. , vol.204 , Issue.2 , pp. 407-419
    • Ladd, A.N.1    Yatskievych, T.A.2    Antin, P.B.3
  • 21
    • 0034093126 scopus 로고    scopus 로고
    • Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperative
    • Barron M, Gao M, Lough J: Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperative. Dev. Dyn. 218(2), 383-393 (2000).
    • (2000) Dev. Dyn , vol.218 , Issue.2 , pp. 383-393
    • Barron, M.1    Gao, M.2    Lough, J.3
  • 22
    • 33646474117 scopus 로고    scopus 로고
    • Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions
    • Yao S, Chen S, Clark J et al.: Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc. Natl Acad. Sci. USA 103(18), 6907-6912 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.18 , pp. 6907-6912
    • Yao, S.1    Chen, S.2    Clark, J.3
  • 23
    • 44349175948 scopus 로고    scopus 로고
    • + embryonic-stem-cellderived population
    • •Identification of a human cardiac progenitor derived from hESCs
    • + embryonic-stem-cellderived population. Nature 453(7194), 524-528 (2008). •Identification of a human cardiac progenitor derived from hESCs.
    • (2008) Nature , vol.453 , Issue.7194 , pp. 524-528
    • Yang, L.1    Soonpaa, M.H.2    Adler, E.D.3
  • 24
    • 0035252543 scopus 로고    scopus 로고
    • Wnt antagonism initiates cardiogenesis in Xenopus laevis
    • Schneider VA, Mercola M: Wnt antagonism initiates cardiogenesis in Xenopus laevis. Genes Dev. 15(3), 304-315 (2001).
    • (2001) Genes Dev. , vol.15 , Issue.3 , pp. 304-315
    • Schneider, V.A.1    Mercola, M.2
  • 25
    • 0035252357 scopus 로고    scopus 로고
    • Inhibition of Wnt activity induces heart formation from posterior mesoderm
    • Marvin MJ, Di Rocco G, Gardiner A, Bush SM, Lassar AB: Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev. 15(3), 316-327 (2001).
    • (2001) Genes Dev. , vol.15 , Issue.3 , pp. 316-327
    • Marvin, M.J.1    Di Rocco, G.2    Gardiner, A.3    Bush, S.M.4    Lassar, A.B.5
  • 26
    • 65349162225 scopus 로고    scopus 로고
    • Cardiomyogenic differentiation of embryoid bodies is promoted by rotary orbital suspension culture
    • Sargent CY, Berguig GY, McDevitt TC: Cardiomyogenic differentiation of embryoid bodies is promoted by rotary orbital suspension culture. Tissue Eng. Part A 15(2), 331-342 (2009).
    • (2009) Tissue Eng. Part A , vol.15 , Issue.2 , pp. 331-342
    • Sargent, C.Y.1    Berguig, G.Y.2    McDevitt, T.C.3
  • 27
    • 74849140306 scopus 로고    scopus 로고
    • Hydrodynamic modulation of embryonic stem cell differentiation by rotary orbital suspension culture
    • Sargent CY, Berguig GY, Kinney MA et al.: Hydrodynamic modulation of embryonic stem cell differentiation by rotary orbital suspension culture. Biotechnol. Bioeng. 105(3), 611-626 (2010).
    • (2010) Biotechnol. Bioeng , vol.105 , Issue.3 , pp. 611-626
    • Sargent, C.Y.1    Berguig, G.Y.2    Kinney, M.A.3
  • 28
    • 70350131483 scopus 로고    scopus 로고
    • Generation of functional ventricular heart muscle from mouse ventricular progenitor cells
    • Domian IJ, Chiravuri M, van der Meer P et al.: Generation of functional ventricular heart muscle from mouse ventricular progenitor cells. Science 326(5951), 426-429 (2009).
    • (2009) Science , vol.326 , Issue.5951 , pp. 426-429
    • Domian, I.J.1    Chiravuri, M.2    Van Der Meer, P.3
  • 29
    • 13944282215 scopus 로고    scopus 로고
    • Microarray ana lysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P et al.: Microarray ana lysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433(7027), 769-773 (2005).
    • (2005) Nature , vol.433 , Issue.7027 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3
  • 30
    • 33847323881 scopus 로고    scopus 로고
    • DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
    • Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R: DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Genet. 39(3), 380-385 (2007).
    • (2007) Nat. Genet. , vol.39 , Issue.3 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3    Jaenisch, R.4    Blelloch, R.5
  • 32
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • Kanellopoulou C, Muljo SA, Kung AL et al.: Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19(4), 489-501 (2005).
    • (2005) Genes Dev. , vol.19 , Issue.4 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3
  • 33
    • 0242266620 scopus 로고    scopus 로고
    • Dicer is essential for mouse development
    • Bernstein E, Kim SY, Carmell MA et al.: Dicer is essential for mouse development. Nat. Genet. 35(3), 215-217 (2003).
    • (2003) Nat. Genet. , vol.35 , Issue.3 , pp. 215-217
    • Bernstein, E.1    Kim, S.Y.2    Carmell, M.A.3
  • 34
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Zhao Y, Samal E, Srivastava D: Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436(7048), 214-220 (2005).
    • (2005) Nature , vol.436 , Issue.7048 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 35
    • 34147153781 scopus 로고    scopus 로고
    • Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
    • Zhao Y, Ransom JF, Li A et al.: Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129(2), 303-317 (2007).
    • (2007) Cell. , vol.129 , Issue.2 , pp. 303-317
    • Zhao, Y.1    Ransom, J.F.2    Li, A.3
  • 36
    • 33847038668 scopus 로고    scopus 로고
    • MicroRNAs play an essential role in the development of cardiac hypertrophy
    • Sayed D, Hong C, Chen IY, Lypowy J, Abdellatif M: MicroRNAs play an essential role in the development of cardiac hypertrophy Circ. Res. 100(3), 416-424 (2007).
    • (2007) Circ. Res. , vol.100 , Issue.3 , pp. 416-424
    • Sayed, D.1    Hong, C.2    Chen, I.Y.3    Lypowy, J.4    Abdellatif, M.5
  • 37
    • 34249279050 scopus 로고    scopus 로고
    • MicroRNA-133 controls cardiac hypertrophy
    • Care A, Catalucci D, Felicetti F et al.: MicroRNA-133 controls cardiac hypertrophy Nat. Med. 13(5), 613-618 (2007).
    • (2007) Nat. Med. , vol.13 , Issue.5 , pp. 613-618
    • Care, A.1    Catalucci, D.2    Felicetti, F.3
  • 38
    • 39749140336 scopus 로고    scopus 로고
    • MicroRNA regulation of cell lineages in mouse and human embryonic stem cells
    • ••First demonstration that miRNAs control hESC differentiation
    • Ivey KN, Muth A, Arnold J et al.: MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell 2(3), 219-229 (2008). ••First demonstration that miRNAs control hESC differentiation.
    • (2008) Cell. Stem Cell. , vol.2 , Issue.3 , pp. 219-229
    • Ivey, K.N.1    Muth, A.2    Arnold, J.3
  • 39
    • 21244431578 scopus 로고    scopus 로고
    • Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes
    • Kawamura T, Ono K, Morimoto T et al.: Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes. J. Biol. Chem. 280(20), 19682-19688 (2005).
    • (2005) J. Biol. Chem. , vol.280 , Issue.20 , pp. 19682-19688
    • Kawamura, T.1    Ono, K.2    Morimoto, T.3
  • 40
    • 66649127942 scopus 로고    scopus 로고
    • Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
    • ••Determined a role for chromatin remodeling in directing cardiac differentiation
    • Takeuchi JK, Bruneau BG: Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature 459(7247), 708-711 (2009). ••Determined a role for chromatin remodeling in directing cardiac differentiation.
    • (2009) Nature , vol.459 , Issue.7247 , pp. 708-711
    • Takeuchi, J.K.1    Bruneau, B.G.2
  • 41
    • 33751002976 scopus 로고    scopus 로고
    • Cardiac bodies: A novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu C, Police S, Hassanipour M, Gold JD: Cardiac bodies: a novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells. Stem Cells Dev. 15(5), 631-639 (2006).
    • (2006) Stem Cells Dev. , vol.15 , Issue.5 , pp. 631-639
    • Xu, C.1    Police, S.2    Hassanipour, M.3    Gold, J.D.4
  • 42
    • 74049156859 scopus 로고    scopus 로고
    • Nongenetic method for purifying stem cell-derived cardiomyocytes
    • Hattori F, Chen H, Yamashita H et al.: Nongenetic method for purifying stem cell-derived cardiomyocytes. Nat. Methods 7(1), 61-66 (2010).
    • (2010) Nat. Methods , vol.7 , Issue.1 , pp. 61-66
    • Hattori, F.1    Chen, H.2    Yamashita, H.3
  • 43
    • 34547823031 scopus 로고    scopus 로고
    • Identification and selection of cardiomyocytes during human embryonic stem cell differentiation
    • Huber I, Itzhaki I, Caspi O et al.: Identification and selection of cardiomyocytes during human embryonic stem cell differentiation. FASEB J. 21(10), 2551-2563 (2007).
    • (2007) FASEB J. , vol.21 , Issue.10 , pp. 2551-2563
    • Huber, I.1    Itzhaki, I.2    Caspi, O.3
  • 44
    • 47249107353 scopus 로고    scopus 로고
    • Highly enriched cardiomyocytes from human embryonic stem cells
    • Xu XQ, Zweigerdt R, Soo SY et al.: Highly enriched cardiomyocytes from human embryonic stem cells. Cytotherapy 10(4), 376-389 (2008).
    • (2008) Cytotherapy , vol.10 , Issue.4 , pp. 376-389
    • Xu, X.Q.1    Zweigerdt, R.2    Soo, S.Y.3
  • 45
    • 65249179464 scopus 로고    scopus 로고
    • Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes
    • Kita-Matsuo H, Barcova M, Prigozhina N et al.: Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS ONE 4(4), e5046 (2009).
    • (2009) PLoS ONE , vol.4 , Issue.4
    • Kita-Matsuo, H.1    Barcova, M.2    Prigozhina, N.3
  • 46
    • 35549006752 scopus 로고    scopus 로고
    • Transgenic enrichment of cardiomyocytes from human embryonic stem cells
    • Anderson D, Self T, Mellor IR, Goh G, Hill SJ, Denning C: Transgenic enrichment of cardiomyocytes from human embryonic stem cells. Mol. Ther. 15(11), 2027-2036 (2007).
    • (2007) Mol. Ther. , vol.15 , Issue.11 , pp. 2027-2036
    • Anderson, D.1    Self, T.2    Mellor, I.R.3    Goh, G.4    Hill, S.J.5    Denning, C.6
  • 47
    • 33645158637 scopus 로고    scopus 로고
    • Nanostructured probes for RNA detection in living cells
    • Santangelo P, Nitin N, Bao G: Nanostructured probes for RNA detection in living cells. Ann. Biomed. Eng. 34(1), 39-50 (2006).
    • (2006) Ann. Biomed. Eng , vol.34 , Issue.1 , pp. 39-50
    • Santangelo, P.1    Nitin, N.2    Bao, G.3
  • 48
    • 33845442108 scopus 로고    scopus 로고
    • Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart
    • Wu SM, Fujiwara Y, Cibulsky SM et al.: Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 127(6), 1137-1150 (2006).
    • (2006) Cell. , vol.127 , Issue.6 , pp. 1137-1150
    • Wu, S.M.1    Fujiwara, Y.2    Cibulsky, S.M.3
  • 49
    • 24944570013 scopus 로고    scopus 로고
    • Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation
    • Kouskoff V, Lacaud G, Schwantz S, Fehling HJ, Keller G: Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation. Proc. Natl Acad. Sci. USA 102(37), 13170-13175 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , Issue.37 , pp. 13170-13175
    • Kouskoff, V.1    Lacaud, G.2    Schwantz, S.3    Fehling, H.J.4    Keller, G.5
  • 50
    • 0041827036 scopus 로고    scopus 로고
    • Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation
    • Fehling HJ, Lacaud G, Kubo A et al.: Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development 130(17), 4217-4227 (2003).
    • (2003) Development , vol.130 , Issue.17 , pp. 4217-4227
    • Fehling, H.J.1    Lacaud, G.2    Kubo, A.3
  • 51
    • 33750456216 scopus 로고    scopus 로고
    • + cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages
    • •Among the first studies to demonstrate that major cardiac lineages may arise from a common progenitor
    • + cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev. Cell 11(5), 723-732 (2006). •Among the first studies to demonstrate that major cardiac lineages may arise from a common progenitor.
    • (2006) Dev. Cell. , vol.11 , Issue.5 , pp. 723-732
    • Kattman, S.J.1    Huber, T.L.2    Keller, G.M.3
  • 52
    • 33845457194 scopus 로고    scopus 로고
    • + progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification
    • •Among the first studies to demonstrate that major cardiac lineages may arise from a common progenitor
    • + progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127(6), 1151-1165 (2006). •Among the first studies to demonstrate that major cardiac lineages may arise from a common progenitor.
    • (2006) Cell. , vol.127 , Issue.6 , pp. 1151-1165
    • Moretti, A.1    Caron, L.2    Nakano, A.3
  • 53
    • 67650071028 scopus 로고    scopus 로고
    • Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages
    • •Identification of human cardiac progenitors derived from hESCs
    • Bu L, Jiang X, Martin-Puig S et al.: Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature 460(7251), 113-117 (2009). •Identification of human cardiac progenitors derived from hESCs.
    • (2009) Nature , vol.460 , Issue.7251 , pp. 113-117
    • Bu, L.1    Jiang, X.2    Martin-Puig, S.3
  • 54
    • 0033836865 scopus 로고    scopus 로고
    • MesP1 and MesP2 are essential for the development of cardiac mesoderm
    • Kitajima S, Takagi A, Inoue T, Saga Y: MesP1 and MesP2 are essential for the development of cardiac mesoderm. Development 127(15), 3215-3226 (2000).
    • (2000) Development , vol.127 , Issue.15 , pp. 3215-3226
    • Kitajima, S.1    Takagi, A.2    Inoue, T.3    Saga, Y.4
  • 55
    • 0029839904 scopus 로고    scopus 로고
    • MesP1: A novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation
    • Saga Y, Hata N, Kobayashi S, Magnuson T, Seldin MF, Taketo MM: MesP1: a novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation. Development 122(9), 2769-2778 (1996).
    • (1996) Development , vol.122 , Issue.9 , pp. 2769-2778
    • Saga, Y.1    Hata, N.2    Kobayashi, S.3    Magnuson, T.4    Seldin, M.F.5    Taketo, M.M.6
  • 56
    • 0034449141 scopus 로고    scopus 로고
    • Mesp1 expression is the earliest sign of cardiovascular development
    • Saga Y, Kitajima S, Miyagawa-Tomita S: Mesp1 expression is the earliest sign of cardiovascular development. Trends Cardiovasc. Med. 10(8), 345-352 (2000).
    • (2000) Trends Cardiovasc. Med. , vol.10 , Issue.8 , pp. 345-352
    • Saga, Y.1    Kitajima, S.2    Miyagawa-Tomita, S.3
  • 57
    • 0032841613 scopus 로고    scopus 로고
    • MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube
    • Saga Y, Miyagawa-Tomita S, Takagi A, Kitajima S, Miyazaki J, Inoue T: MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube. Development 126(15), 3437-3447 (1999).
    • (1999) Development , vol.126 , Issue.15 , pp. 3437-3447
    • Saga, Y.1    Miyagawa-Tomita, S.2    Takagi, A.3    Kitajima, S.4    Miyazaki, J.5    Inoue, T.6
  • 58
    • 48649087364 scopus 로고    scopus 로고
    • Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification
    • Bondue A, Lapouge G, Paulissen C et al.: Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification. Cell Stem Cell 3(1), 69-84 (2008).
    • (2008) Cell. Stem Cell. , vol.3 , Issue.1 , pp. 69-84
    • Bondue, A.1    Lapouge, G.2    Paulissen, C.3
  • 59
    • 48649106835 scopus 로고    scopus 로고
    • Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs
    • Lindsley RC, Gill JG, Murphy TL et al.: Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs. Cell Stem Cell 3(1), 55-68 (2008).
    • (2008) Cell. Stem Cell. , vol.3 , Issue.1 , pp. 55-68
    • Lindsley, R.C.1    Gill, J.G.2    Murphy, T.L.3
  • 60
    • 40249093060 scopus 로고    scopus 로고
    • MesP1 drives vertebrate cardiovascular differentiation through DKK-1-mediated blockade of Wnt-signalling
    • David R, Brenner C, Stieber J et al.: MesP1 drives vertebrate cardiovascular differentiation through DKK-1-mediated blockade of Wnt-signalling. Nat. Cell Biol. 10(3), 338-345 (2008).
    • (2008) Nat. Cell. Biol. , vol.10 , Issue.3 , pp. 338-345
    • David, R.1    Brenner, C.2    Stieber, J.3
  • 61
    • 0942276446 scopus 로고    scopus 로고
    • Properties of four human embryonic stem cell lines maintained in a feeder-free culture system
    • Carpenter MK, Rosler ES, Fisk GJ et al.: Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Dev. Dyn. 229(2), 243-258 (2004).
    • (2004) Dev. Dyn , vol.229 , Issue.2 , pp. 243-258
    • Carpenter, M.K.1    Rosler, E.S.2    Fisk, G.J.3
  • 62
    • 72849142382 scopus 로고    scopus 로고
    • Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures
    • ••Determined that undifferentiated hESC cultures contain stem cell populations with predetermined fates
    • King FW, Ritner C, Liszewski W et al.: Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures. Stem Cells Dev. 18(10), 1441-1450 (2009). ••Determined that undifferentiated hESC cultures contain stem cell populations with predetermined fates.
    • (2009) Stem Cells Dev. , vol.18 , Issue.10 , pp. 1441-1450
    • King, F.W.1    Ritner, C.2    Liszewski, W.3
  • 63
    • 24044551612 scopus 로고    scopus 로고
    • Formation of human myocardium in the rat heart from human embryonic stem cells
    • Laflamme MA, Gold J, Xu C et al.: Formation of human myocardium in the rat heart from human embryonic stem cells. Am. J. Pathol. 167(3), 663-671 (2005).
    • (2005) Am. J. Pathol. , vol.167 , Issue.3 , pp. 663-671
    • Laflamme, M.A.1    Gold, J.2    Xu, C.3
  • 64
    • 36249025247 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction
    • van Laake LW, Passier R, Monshouwer-Kloots J et al.: Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Res. 1(1), 9-24 (2007).
    • (2007) Stem Cell. Res. , vol.1 , Issue.1 , pp. 9-24
    • Van Laake, L.W.1    Passier, R.2    Monshouwer-Kloots, J.3
  • 65
    • 38449111775 scopus 로고    scopus 로고
    • Monitoring of cell therapy and assessment of cardiac function using magnetic resonance imaging in a mouse model of myocardial infarction
    • van Laake LW, Passier R, Monshouwer-Kloots J et al.: Monitoring of cell therapy and assessment of cardiac function using magnetic resonance imaging in a mouse model of myocardial infarction. Nat. Protoc. 2(10), 2551-2567 (2007).
    • (2007) Nat. Protoc. , vol.2 , Issue.10 , pp. 2551-2567
    • Van Laake, L.W.1    Passier, R.2    Monshouwer-Kloots, J.3
  • 66
    • 43449126812 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents
    • •Extended the assessment of cardiac function in mice to 12 weeks following hESC-derived CM transplantation, underscoring the importance of long-term ana lysis and the challenges to using rodents as a preclinical model for myocardial therapy
    • van Laake LW, Passier R, Doevendans PA, Mummery CL: Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents. Circ. Res. 102(9), 1008-1010 (2008). •Extended the assessment of cardiac function in mice to 12 weeks following hESC-derived CM transplantation, underscoring the importance of long-term ana lysis and the challenges to using rodents as a preclinical model for myocardial therapy.
    • (2008) Circ. Res. , vol.102 , Issue.9 , pp. 1008-1010
    • Van Laake, L.W.1    Passier, R.2    Doevendans, P.A.3    Mummery, C.L.4
  • 67
    • 34848923726 scopus 로고    scopus 로고
    • Human embryonic stem cell transplantation to repair the infarcted myocardium
    • Leor J, Gerecht S, Cohen S et al.: Human embryonic stem cell transplantation to repair the infarcted myocardium. Heart 93(10), 1278-1284 (2007).
    • (2007) Heart , vol.93 , Issue.10 , pp. 1278-1284
    • Leor, J.1    Gerecht, S.2    Cohen, S.3
  • 68
    • 29244488216 scopus 로고    scopus 로고
    • Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury
    • Kofidis T, Lebl DR, Swijnenburg RJ, Greeve JM, Klima U, Robbins RC: Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury. Eur. J. Cardiothorac. Surg. 29(1), 50-55 (2006).
    • (2006) Eur. J. Cardiothorac. Surg. , vol.29 , Issue.1 , pp. 50-55
    • Kofidis, T.1    Lebl, D.R.2    Swijnenburg, R.J.3    Greeve, J.M.4    Klima, U.5    Robbins, R.C.6
  • 69
    • 35548974727 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts
    • Caspi O, Huber I, Kehat I et al.: Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts. J. Am. Coll. Cardiol. 50(19), 1884-1893 (2007).
    • (2007) J. Am. Coll. Cardiol. , vol.50 , Issue.19 , pp. 1884-1893
    • Caspi, O.1    Huber, I.2    Kehat, I.3
  • 70
    • 68349084601 scopus 로고    scopus 로고
    • Left ventricular remodeling after myocardial infarction: Characterization of a swine model on β-blocker therapy
    • Angeli FS, Shapiro M, Amabile N et al.: Left ventricular remodeling after myocardial infarction: characterization of a swine model on β-blocker therapy. Comp. Med. 59(3), 272-279 (2009).
    • (2009) Comp. Med. , vol.59 , Issue.3 , pp. 272-279
    • Angeli, F.S.1    Shapiro, M.2    Amabile, N.3
  • 71
    • 24944577389 scopus 로고    scopus 로고
    • Mechanisms of ventricular fibrillation in canine models of congestive heart failure and ischemia assessed by in vivo noncontact mapping
    • Everett TH 4th, Wilson EE, Foreman S, Olgin JE: Mechanisms of ventricular fibrillation in canine models of congestive heart failure and ischemia assessed by in vivo noncontact mapping. Circulation 112(11), 1532-1541 (2005).
    • (2005) Circulation , vol.112 , Issue.11 , pp. 1532-1541
    • Everett IV, T.H.1    Wilson, E.E.2    Foreman, S.3    Olgin, J.E.4
  • 73
    • 33646692132 scopus 로고    scopus 로고
    • Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells
    • Drukker M, Katchman H, Katz G et al.: Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells. Stem Cells 24(2), 221-229 (2006).
    • (2006) Stem Cells , vol.24 , Issue.2 , pp. 221-229
    • Drukker, M.1    Katchman, H.2    Katz, G.3
  • 74
    • 54349128090 scopus 로고    scopus 로고
    • Cardiomyocytes from embryonic stem cells: Towards human therapy
    • Foldes G, Harding SE, Ali NN: Cardiomyocytes from embryonic stem cells: towards human therapy. Expert Opin. Biol. Ther. 8(10), 1473-1483 (2008).
    • (2008) Expert Opin. Biol. Ther. , vol.8 , Issue.10 , pp. 1473-1483
    • Foldes, G.1    Harding, S.E.2    Ali, N.N.3
  • 75
    • 41449094683 scopus 로고    scopus 로고
    • Lives of a heart cell: Tracing the origins of cardiac progenitors
    • Martin-Puig S, Wang Z, Chien KR: Lives of a heart cell: tracing the origins of cardiac progenitors. Cell Stem Cell 2(4), 320-331 (2008).
    • (2008) Cell. Stem Cell. , vol.2 , Issue.4 , pp. 320-331
    • Martin-Puig, S.1    Wang, Z.2    Chien, K.R.3
  • 76
    • 39349106325 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
    • Murry CE, Keller G: Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132(4), 661-680 (2008).
    • (2008) Cell. , vol.132 , Issue.4 , pp. 661-680
    • Murry, C.E.1    Keller, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.