메뉴 건너뛰기




Volumn 10, Issue 4, 2008, Pages 376-389

Highly enriched cardiomyocytes from human embryonic stem cells

Author keywords

Arrhythmia; Cardiomyocytes; Cell therapy; Differentiation; Human embryonic stem cells (hESC); QT interval; Safety pharmacology; Selection; Teratoma; Transgenic lines

Indexed keywords

MYOSIN HEAVY CHAIN ALPHA; NEOMYCIN;

EID: 47249107353     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.1080/14653240802105307     Document Type: Article
Times cited : (90)

References (45)
  • 1
    • 30944432553 scopus 로고    scopus 로고
    • Cell-based cardiac repair: Reflections at the 10-year point
    • Murry, CE, Field, LJ and Menasche, P. (2005) Cell-based cardiac repair: reflections at the 10-year point. Circulation, 112, pp. 3174-3183.
    • (2005) Circulation , vol.112 , pp. 3174-3183
    • Murry, C.E.1    Field, L.J.2    Menasche, P.3
  • 2
    • 0037934446 scopus 로고    scopus 로고
    • Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host
    • Leobon, B., Garcin, I. Menasche, P. et al. (2003) Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host. Proc Natl Acad Sci USA, 100, pp. 7808-7811.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7808-7811
    • Leobon, B.1    Garcin, I.2    Menasche, P.3
  • 3
    • 1942517003 scopus 로고    scopus 로고
    • Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
    • Balsam, LB, Wagers, AJ Christensen, JL et al. (2004) Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature, 428, pp. 668-673.
    • (2004) Nature , vol.428 , pp. 668-673
    • Balsam, L.B.1    Wagers, A.J.2    Christensen, J.L.3
  • 4
    • 11144356049 scopus 로고    scopus 로고
    • Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
    • Murry, CE, Soonpaa, MH Reinecke, H. et al. (2004) Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature, 428, pp. 664-668.
    • (2004) Nature , vol.428 , pp. 664-668
    • Murry, C.E.1    Soonpaa, M.H.2    Reinecke, H.3
  • 5
    • 2442675144 scopus 로고    scopus 로고
    • Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation
    • Nygren, JM, Jovinge, S. Breitbach, M. et al. (2004) Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med, 10, pp. 494-501.
    • (2004) Nat Med , vol.10 , pp. 494-501
    • Nygren, J.M.1    Jovinge, S.2    Breitbach, M.3
  • 6
    • 33644821605 scopus 로고    scopus 로고
    • Differentiation and lineage selection of mouse embryonic stem cells in a stirred bench scale bioreactor with automated process control
    • Schroeder, M., Niebruegge, S. Werner, A. et al. (2005) Differentiation and lineage selection of mouse embryonic stem cells in a stirred bench scale bioreactor with automated process control. Biotechnol Bioeng, 92, pp. 920-933.
    • (2005) Biotechnol Bioeng , vol.92 , pp. 920-933
    • Schroeder, M.1    Niebruegge, S.2    Werner, A.3
  • 7
    • 5044221669 scopus 로고    scopus 로고
    • Electromechanical integration of cardiomyocytes derived from human embryonic stem cells
    • Kehat, I., Khimovich, L. Caspi, O. et al. (2004) Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol, 22, pp. 1282-1289.
    • (2004) Nat Biotechnol , vol.22 , pp. 1282-1289
    • Kehat, I.1    Khimovich, L.2    Caspi, O.3
  • 8
    • 0030016231 scopus 로고    scopus 로고
    • Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts
    • Klug, MG, Soonpaa, MH, Koh, GY and Field, LJ. (1996) Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts. J Clin Invest, 98, pp. 216-224.
    • (1996) J Clin Invest , vol.98 , pp. 216-224
    • Klug, M.G.1    Soonpaa, M.H.2    Koh, G.Y.3    Field, L.J.4
  • 9
    • 33749367585 scopus 로고    scopus 로고
    • Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium
    • Kolossov, E., Bostani, T. Roell, W. et al. (2006) Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium. J Exp Med, 203, pp. 2315-2327.
    • (2006) J Exp Med , vol.203 , pp. 2315-2327
    • Kolossov, E.1    Bostani, T.2    Roell, W.3
  • 10
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme, MA, Chen, KY Naumova, AV et al. (2007) Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nature Biotechnol, 25, pp. 1015-1024.
    • (2007) Nature Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3
  • 11
    • 36249025247 scopus 로고    scopus 로고
    • Human embryonicstem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction
    • van Laake, LW, Passier, R. Monshouwer-Kloots, J. et al. (2007) Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Res, 1, pp. 9-24.
    • (2007) Stem Cell Res , vol.1 , pp. 9-24
    • van Laake, L.W.1    Passier, R.2    Monshouwer-Kloots, J.3
  • 12
    • 0038300672 scopus 로고    scopus 로고
    • Human embryonic stem cells develop into multiple types of cardiac myocytes: Action Potential characterization
    • He, JQ, Ma, Y. Lee, Y. et al. (2003) Human embryonic stem cells develop into multiple types of cardiac myocytes: Action potential characterization. Circ Res, 93, pp. 32-39.
    • (2003) Circ Res , vol.93 , pp. 32-39
    • He, J.Q.1    Ma, Y.2    Lee, Y.3
  • 13
    • 0034904645 scopus 로고    scopus 로고
    • Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
    • Kehat, I., Kenyagin-Karsenti, D. Snir, M. et al. (2001) Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest, 108, pp. 407-414.
    • (2001) J Clin Invest , vol.108 , pp. 407-414
    • Kehat, I.1    Kenyagin-Karsenti, D.2    Snir, M.3
  • 14
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells
    • Mummery, C., Ward-van Oostwaard, D Doevendans, P. et al. (2003) Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells. Circulation, 107, pp. 2733-2740.
    • (2003) Circulation , vol.107 , pp. 2733-2740
    • Mummery, C.1    Ward-van Oostwaard, D.2    Doevendans, P.3
  • 15
    • 0037144701 scopus 로고    scopus 로고
    • Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu, C., Police, S., Rao, N. and Carpenter, MK. (2002) Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ Res, 91, pp. 501-508.
    • (2002) Circ Res , vol.91 , pp. 501-508
    • Xu, C.1    Police, S.2    Rao, N.3    Carpenter, M.K.4
  • 16
    • 42149094990 scopus 로고    scopus 로고
    • Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK
    • Graichen, R., Xu, QX Braam, SR et al. (2008) Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK. Differentiation, 76, pp. 357-370.
    • (2008) Differentiation , vol.76 , pp. 357-370
    • Graichen, R.1    Xu, Q.X.2    Braam, S.R.3
  • 17
    • 20344372655 scopus 로고    scopus 로고
    • Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures
    • Passier, R., Oostwaard, DW Snapper, J. et al. (2005) Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures. Stem Cells, 23, pp. 772-780.
    • (2005) Stem Cells , vol.23 , pp. 772-780
    • Passier, R.1    Oostwaard, D.W.2    Snapper, J.3
  • 19
    • 34247647982 scopus 로고    scopus 로고
    • Transplantation of undifferentiated murine embryonic stem cells in the heart: Teratoma formation and immune response
    • Nussbaum, J., Minami, E. Laflamme, MA et al. (2007) Transplantation of undifferentiated murine embryonic stem cells in the heart: Teratoma formation and immune response. FASEB J, 21, pp. 1345-1357.
    • (2007) FASEB J , vol.21 , pp. 1345-1357
    • Nussbaum, J.1    Minami, E.2    Laflamme, M.A.3
  • 20
    • 0033664460 scopus 로고    scopus 로고
    • Selection of ventricular-like cardiomyocytes from ES cells in vitro
    • Muller, M., Fleischmann, BK Selbert, S. et al. (2000) Selection of ventricular-like cardiomyocytes from ES cells in vitro. FASEB J, 14, pp. 2540-2548.
    • (2000) FASEB J , vol.14 , pp. 2540-2548
    • Muller, M.1    Fleischmann, B.K.2    Selbert, S.3
  • 21
    • 34547823031 scopus 로고    scopus 로고
    • Identification and selection of cardiomyocytes during human embryonic stem cell differentiation
    • Huber, I., Itzhaki, I. Caspi, O. et al. (2007) Identification and selection of cardiomyocytes during human embryonic stem cell differentiation. FASEB J, 21, pp. 2551-2563.
    • (2007) FASEB J , vol.21 , pp. 2551-2563
    • Huber, I.1    Itzhaki, I.2    Caspi, O.3
  • 22
    • 35549006752 scopus 로고    scopus 로고
    • Transgenic enrichment of cardiomyocytes from human embryonic stem cells
    • Anderson, D., Self, T. Mellor, IR et al. (2007) Transgenic enrichment of cardiomyocytes from human embryonic stem cells. Mol Ther, 15, pp. 2027-2036.
    • (2007) Mol Ther , vol.15 , pp. 2027-2036
    • Anderson, D.1    Self, T.2    Mellor, I.R.3
  • 23
    • 84879070030 scopus 로고    scopus 로고
    • Cardiomyocyte production in mass suspension culture: Embryonic stem cells as a source for great amounts of functional cardiomyocytes
    • Tissue Engineering
    • Niebruegge, S., Nehring, A. Baer, H. et al. Cardiomyocyte production in mass suspension culture: Embryonic stem cells as a source for great amounts of functional cardiomyocytes. Tissue Engineering
    • Niebruegge, S.1    Nehring, A.2    Baer, H.3
  • 24
    • 34248569914 scopus 로고    scopus 로고
    • A method for genetic modification of human embryonic stem cells using electroporation
    • Costa, M., Dottori, M. Sourris, K. et al. (2007) A method for genetic modification of human embryonic stem cells using electroporation. Nat Protoc, 2, pp. 792-796.
    • (2007) Nat Protoc , vol.2 , pp. 792-796
    • Costa, M.1    Dottori, M.2    Sourris, K.3
  • 25
    • 0037336820 scopus 로고    scopus 로고
    • Homologous recombination in human embryonic stem cells
    • Zwaka, TP and Thomson, JA. (2003) Homologous recombination in human embryonic stem cells. Nat Biotechnol, 21, pp. 319-321.
    • (2003) Nat Biotechnol , vol.21 , pp. 319-321
    • Zwaka, T.P.1    Thomson, J.A.2
  • 26
    • 0242468552 scopus 로고    scopus 로고
    • Generation of confluent cardiomyocyte monolayers derived from embryonic stem cells in suspension: A cell source for new therapies and screening strategies
    • Zweigerdt, R., Burg, M. Willbold, E. et al. (2003) Generation of confluent cardiomyocyte monolayers derived from embryonic stem cells in suspension: A cell source for new therapies and screening strategies. Cytotherapy, 5, pp. 399-413.
    • (2003) Cytotherapy , vol.5 , pp. 399-413
    • Zweigerdt, R.1    Burg, M.2    Willbold, E.3
  • 27
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro
    • Reubinoff, BE, Pera, MF Fong, CY et al. (2000) Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro. Nat Biotechnol, 18, pp. 399-404.
    • (2000) Nat Biotechnol , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3
  • 28
    • 18744411285 scopus 로고    scopus 로고
    • The hESC line Envy expresses high levels of GFP in all differentiated progeny
    • Costa, M., Dottori, M. Ng, E. et al. (2005) The hESC line Envy expresses high levels of GFP in all differentiated progeny. Nat Methods, 2, pp. 259-260.
    • (2005) Nat Methods , vol.2 , pp. 259-260
    • Costa, M.1    Dottori, M.2    Ng, E.3
  • 29
    • 33745158972 scopus 로고    scopus 로고
    • Patterning the heart, a template for human cardiomyocyte development
    • Chuva de Sousa Lopes, SM, Hassink, RJ Feijen, A. et al. (2006) Patterning the heart, a template for human cardiomyocyte development. Dev Dyn, 235, pp. 1994-2002.
    • (2006) Dev Dyn , vol.235 , pp. 1994-2002
    • Chuva de Sousa Lopes, S.M.1    Hassink, R.J.2    Feijen, A.3
  • 30
    • 0346056964 scopus 로고    scopus 로고
    • Molecular regulation of cardiac chamber-specific gene expression
    • Small, EM and Krieg, PA. (2004) Molecular regulation of cardiac chamber-specific gene expression. Trends Cardiovasc Med, 14, pp. 13-18.
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 13-18
    • Small, E.M.1    Krieg, P.A.2
  • 31
    • 4544254897 scopus 로고    scopus 로고
    • Micro-electrode arrays in cardiac safety pharmacology: A novel tool to study QT interval prolongation
    • Meyer, T., Boven, KH, Gunther, E. and Fejtl, M. (2004) Micro-electrode arrays in cardiac safety pharmacology: A novel tool to study QT interval prolongation. Drug Saf, 27, pp. 763-772.
    • (2004) Drug Saf , vol.27 , pp. 763-772
    • Meyer, T.1    Boven, K.H.2    Gunther, E.3    Fejtl, M.4
  • 32
    • 0026319641 scopus 로고
    • Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: Comparison between quinidine, lidocaine, flecainide, propranolol and sotalol
    • Weissenburger, J., Davy, JM Chezalviel, F. et al. (1991) Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: Comparison between quinidine, lidocaine, flecainide, propranolol and sotalol. J Pharmacol Exp Ther, 259, pp. 871-883.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 871-883
    • Weissenburger, J.1    Davy, J.M.2    Chezalviel, F.3
  • 33
    • 4444267925 scopus 로고    scopus 로고
    • Beta-adrenergic and muscarinic modulation of human embryonic stem cell-derived cardiomyocytes
    • Reppel, M., Boettinger, C. and Hescheler, J. (2004) Beta-adrenergic and muscarinic modulation of human embryonic stem cell-derived cardiomyocytes. Cell Physiol Biochem, 14, pp. 187-196.
    • (2004) Cell Physiol Biochem , vol.14 , pp. 187-196
    • Reppel, M.1    Boettinger, C.2    Hescheler, J.3
  • 34
    • 11244249952 scopus 로고    scopus 로고
    • Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell-based pacemakers
    • Xue, T., Cho, HC Akar, FG et al. (2005) Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell-based pacemakers. Circulation, 111, pp. 11-20.
    • (2005) Circulation , vol.111 , pp. 11-20
    • Xue, T.1    Cho, H.C.2    Akar, F.G.3
  • 36
    • 0037390873 scopus 로고    scopus 로고
    • Chamber-specific differentiation of Nkx2
    • Hidaka, K., Lee, JK Kim, HS et al. (2003) Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells. FASEB J, 17, pp. 740-742.
    • (2003) FASEB J , vol.17 , pp. 740-742
    • Hidaka, K.1    Lee, J.K.2    Kim, H.S.3
  • 37
    • 33751002976 scopus 로고    scopus 로고
    • Cardiac bodies: A novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells
    • Xu, C., Police, S., Hassanipour, M. and Gold, JD. (2006) Cardiac bodies: a novel culture method for enrichment of cardiomyocytes derived from human embryonic stem cells. Stem Cells Dev, 15, pp. 631-639.
    • (2006) Stem Cells Dev , vol.15 , pp. 631-639
    • Xu, C.1    Police, S.2    Hassanipour, M.3    Gold, J.D.4
  • 38
    • 34648847052 scopus 로고    scopus 로고
    • Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts
    • Dai, W., Field, LJ Rubart, M. et al. (2007) Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts. J Mol Cell Cardiol, 43, pp. 504-516.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 504-516
    • Dai, W.1    Field, L.J.2    Rubart, M.3
  • 39
    • 34848923726 scopus 로고    scopus 로고
    • Human embryonic stem cell transplantation to repair the infarcted myocardium
    • Leor, J., Gerecht, S. Cohen, S. et al. (2007) Human embryonic stem cell transplantation to repair the infarcted myocardium. Heart (Br Card Soc), 93, pp. 1278-1284.
    • (2007) Heart (Br Card Soc) , vol.93 , pp. 1278-1284
    • Leor, J.1    Gerecht, S.2    Cohen, S.3
  • 40
    • 38349082689 scopus 로고    scopus 로고
    • Creation of engineered human embryonic stem cell lines using phiC31 integrase
    • Thyagarajan, B., Liu, Y. Shin, S. et al. (2008) Creation of engineered human embryonic stem cell lines using phiC31 integrase. Stem Cells, 26, pp. 119-126.
    • (2008) Stem Cells , vol.26 , pp. 119-126
    • Thyagarajan, B.1    Liu, Y.2    Shin, S.3
  • 41
    • 0038471102 scopus 로고    scopus 로고
    • The impact of drug-induced QT interval prolongation on drug discovery and development
    • Fermini, B. and Fossa, AA. (2003) The impact of drug-induced QT interval prolongation on drug discovery and development. Nat Rev Drug Discov, 2, pp. 439-447.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 439-447
    • Fermini, B.1    Fossa, A.A.2
  • 42
    • 27744472015 scopus 로고    scopus 로고
    • Use of preclinical assays to predict risk of drug-induced torsades de pointes
    • Belardinelli, L., Shryock, JC, Wu, L. and Song, Y. (2005) Use of preclinical assays to predict risk of drug-induced torsades de pointes. Heart Rhythm, 2, p. S16.
    • (2005) Heart Rhythm , vol.2
    • Belardinelli, L.1    Shryock, J.C.2    Wu, L.3    Song, Y.4
  • 43
    • 33645737594 scopus 로고    scopus 로고
    • Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
    • Zimmermann, WH, Melnychenko, I. Wasmeier, G. et al. (2006) Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med, 12, pp. 452-458.
    • (2006) Nat Med , vol.12 , pp. 452-458
    • Zimmermann, W.H.1    Melnychenko, I.2    Wasmeier, G.3
  • 44
    • 33846818621 scopus 로고    scopus 로고
    • Tissue engineering of vascularized cardiac muscle from human embryonic stem cells
    • Caspi, O., Lesman, A. Basevitch, Y. et al. (2007) Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ Res, 100, pp. 263-272.
    • (2007) Circ Res , vol.100 , pp. 263-272
    • Caspi, O.1    Lesman, A.2    Basevitch, Y.3
  • 45
    • 33646771766 scopus 로고    scopus 로고
    • Creation of engineered cardiac tissue in vitro from mouse embryonic stem cells
    • Guo, XM, Zhao, YS Chang, HX et al. (2006) Creation of engineered cardiac tissue in vitro from mouse embryonic stem cells. Circulation, 113, pp. 2229-2237.
    • (2006) Circulation , vol.113 , pp. 2229-2237
    • Guo, X.M.1    Zhao, Y.S.2    Chang, H.X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.